# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/as00081.fasta.huge -Q ../query/FLJ00081.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00081, 333 aa vs ./tmplib.10216 library 2210661 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 4.5066+/-0.00345; mu= 13.4556+/- 0.232 mean_var=76.4940+/-17.071, 0's: 0 Z-trim: 2 B-trim: 0 in 0/40 Lambda= 0.146643 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1177 ( 755 res) hf00837a ( 755) 2130 460.2 1.8e-130 KIAA1179 ( 1090 res) hh05402a (1090) 108 32.6 0.13 FLJ00025 ( 955 res) as00025 ( 955) 94 29.6 0.95 KIAA0185 ( 1884 res) ha02717 (1884) 92 29.5 2 KIAA1980 ( 660 res) fj10323s1 ( 660) 83 27.1 3.8 KIAA0733 ( 698 res) hk03729s1 ( 698) 82 26.9 4.5 KIAA1961 ( 943 res) hk07733 ( 943) 82 27.1 5.5 KIAA0251 ( 820 res) ha07028 ( 820) 81 26.8 5.8 KIAA1874 ( 579 res) hk07257s1 ( 579) 79 26.2 6.2 KIAA1767 ( 1960 res) eg01735 (1960) 84 27.8 6.6 KIAA1930 ( 664 res) fj11193 ( 664) 79 26.3 6.8 FLJ00074 ( 191 res) as00074 ( 191) 72 24.2 8.3 KIAA0207 ( 605 res) ha02795 ( 605) 77 25.8 8.5 KIAA1876 ( 803 res) pf01162s1 ( 803) 78 26.1 8.9 KIAA0473 ( 937 res) hh00220 ( 937) 78 26.2 9.8 KIAA0414 ( 492 res) hh00161 ( 492) 75 25.3 10 KIAA1992 ( 853 res) bg00166 ( 853) 77 26.0 11 KIAA1258 ( 479 res) hh15704 ( 479) 74 25.0 11 KIAA1379 ( 457 res) fj05092s1 ( 457) 73 24.8 13 FLJ00347 ( 1752 res) sg00014 (1752) 79 26.7 13 FLJ00055 ( 977 res) as00055 ( 977) 76 25.8 14 KIAA1420 ( 1349 res) hk03917(revised) (1349) 77 26.2 14 KIAA1184 ( 380 res) hg01696a ( 380) 71 24.3 15 KIAA1832 ( 694 res) fg02852(revised) ( 694) 73 25.0 17 KIAA2000 ( 699 res) bf00135 ( 699) 73 25.0 17 KIAA1114 ( 1458 res) fj15925 (1458) 76 26.0 18 KIAA0026 ( 288 res) ha00640 ( 288) 68 23.5 20 KIAA0594 ( 1120 res) hj02896s1 (1120) 74 25.5 20 KIAA1011 ( 3541 res) ff02850 (3541) 79 27.1 20 KIAA0674 ( 1234 res) hk02519 (1234) 74 25.5 21 KIAA0305 ( 1547 res) hg00042 (1547) 74 25.6 25 KIAA0897 ( 419 res) hk09524 ( 419) 68 23.7 25 FLJ00045 ( 272 res) as00045 ( 272) 66 23.1 25 KIAA0894 ( 553 res) hk08775 ( 553) 69 24.1 26 FLJ00335 ( 157 res) sj05150 ( 157) 63 22.2 27 KIAA0283 ( 1471 res) ha06139s1 (1471) 73 25.4 27 KIAA0531 ( 999 res) hg03072 ( 999) 71 24.8 28 KIAA1666 ( 1003 res) fg02554 (1003) 71 24.8 29 KIAA0254 ( 1009 res) ha07011 (1009) 71 24.8 29 KIAA1565 ( 1313 res) bf00184 (1313) 72 25.1 29 KIAA1500 ( 2240 res) hh12031s1 (2240) 74 25.8 31 KIAA1491 ( 757 res) fj08187 ( 757) 69 24.2 32 FLJ00126 ( 878 res) sh01242 ( 878) 69 24.3 35 KIAA1194 ( 575 res) fg00908 ( 575) 67 23.6 36 KIAA0072 ( 503 res) ha01357 ( 503) 66 23.4 38 KIAA1212 ( 802 res) fh00638s1 ( 802) 68 24.0 38 KIAA0847 ( 645 res) hk05395 ( 645) 67 23.7 38 KIAA0870 ( 1019 res) hk06970(revised) (1019) 69 24.4 39 KIAA0882 ( 1291 res) hk07544s1 (1291) 70 24.7 39 KIAA1102 ( 1101 res) bh00035 (1101) 69 24.4 41 >>KIAA1177 ( 755 res) hf00837a (755 aa) initn: 2129 init1: 2129 opt: 2130 Z-score: 2435.8 bits: 460.2 E(): 1.8e-130 Smith-Waterman score: 2130; 99.080% identity (99.387% similar) in 326 aa overlap (10-333:119-444) 10 20 30 FLJ000 DSPPLPHALQLWHELCDLISQNPDKVQSLNVDAIIRGGL :::::::::::::::::::::::::::::: KIAA11 SSDRLDEAAQRLATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGL 90 100 110 120 130 140 40 50 60 70 80 90 FLJ000 TRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA11 TRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIA 150 160 170 180 190 200 100 110 120 130 140 150 FLJ000 AKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA11 AKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQ 210 220 230 240 250 260 160 170 180 190 200 210 FLJ000 GRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA11 GRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQ 270 280 290 300 310 320 220 230 240 250 260 270 FLJ000 VDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA11 VDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWS 330 340 350 360 370 380 280 290 300 310 320 330 FLJ000 MLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKV--RG :::::::::::::::::::::::::::::::::::::::::::::::::::. :: KIAA11 MLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISLF 390 400 410 420 430 440 KIAA11 KWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGL 450 460 470 480 490 500 >>KIAA1179 ( 1090 res) hh05402a (1090 aa) initn: 104 init1: 77 opt: 108 Z-score: 122.1 bits: 32.6 E(): 0.13 Smith-Waterman score: 113; 22.559% identity (48.822% similar) in 297 aa overlap (51-328:223-502) 30 40 50 60 70 80 FLJ000 QNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTV ::. : . . .: .. :. KIAA11 EVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTA 200 210 220 230 240 250 90 100 110 120 130 FLJ000 -RDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQ-----LISRRPL . . : . ::...: :: .. : : . .: .:. . .:.:: . :: KIAA11 SKYYPLVAQHYASLQEYEIAEELYTK---GDRTKDAIDMYTQAGRWEQAHKLAMKCMRPE 260 270 280 290 300 140 150 160 170 180 190 FLJ000 LLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAK .. . . : ..: .: ::. :: :. .:: : . : : :. . . KIAA11 DVSVLYITQ----AQEMEK-----QGKYREAERLYV-TVQEPDLAITMYKKHKLYDDMIR 310 320 330 340 350 200 210 220 230 240 FLJ000 FYEDNGQ--LDDARVILEKATKVNFK-QVDDL----ASVWCQCGELELRHENYDEALRLL . . :.:... : : ... . : . :. : .. ..:: :. KIAA11 LVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVA 360 370 380 390 400 410 250 260 270 280 290 300 FLJ000 RKATALPARR------AEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRI : . :.. :. . : : :. ..: . .: . .:. . . .: KIAA11 RTQGGANAHKHVAYLWAKSLGGEAAV--RLLNKLGLLEAAVDHAADNCSFEFAFEL-SR- 420 430 440 450 460 470 310 320 330 FLJ000 LDLRIATPQIVINYAMFLEEHKYFEESFKVRG : :. ::.. ..::::::.. :::. KIAA11 LALKHKTPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAH 480 490 500 510 520 530 >>FLJ00025 ( 955 res) as00025 (955 aa) initn: 111 init1: 55 opt: 94 Z-score: 106.7 bits: 29.6 E(): 0.95 Smith-Waterman score: 94; 23.585% identity (59.434% similar) in 106 aa overlap (116-214:725-825) 90 100 110 120 130 140 FLJ000 VFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQ-- ::. . .:: . :.:::: .. :.. FLJ000 NIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLD 700 710 720 730 740 750 150 160 170 180 190 FLJ000 NPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHT-----LWVAFAKFYED .: .. : . :..: . ... ..:. : : : :. : ... .:.. . FLJ000 SPGYAAETY----LKMGDLKSLVQLHVET-QRWDEAFALGEKHPEFKDDIYMPYAQWLAE 760 770 780 790 800 200 210 220 230 240 250 FLJ000 NGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRA : ....:. ..:: . FLJ000 NDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCLDIAQDPAQ 810 820 830 840 850 860 >>KIAA0185 ( 1884 res) ha02717 (1884 aa) initn: 128 init1: 72 opt: 92 Z-score: 100.9 bits: 29.5 E(): 2 Smith-Waterman score: 132; 21.182% identity (54.187% similar) in 203 aa overlap (143-331:1576-1760) 120 130 140 150 160 170 FLJ000 EDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHH--VHEWHKRVALHQGRPREIINTYT ..::. ... .:. :.. . .. .. KIAA01 LSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIE 1550 1560 1570 1580 1590 1600 180 190 200 210 FLJ000 EAV-------QTVDPFK--ATGKPHT--LWVAFAKFYEDNGQLDDARVILEKATK-VNFK ::. ...: : . ..:.. ::. . :. . ... ::.. :.: : ..:. KIAA01 EALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFR 1610 1620 1630 1640 1650 1660 220 230 240 250 260 270 FLJ000 QVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVW . .. .:: .:: . . . .....:. .: .:: :::. KIAA01 EEQEKLNVWVALLNLENMYGSQESLTKVFERAV-------QY---NEP--------LKVF 1670 1680 1690 1700 280 290 300 310 320 330 FLJ000 SMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKVRG :::. . :: . .:.:.: . :.:. :: ... : .: KIAA01 LHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALEC 1710 1720 1730 1740 1750 1760 KIAA01 LPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDV 1770 1780 1790 1800 1810 1820 >>KIAA1980 ( 660 res) fj10323s1 (660 aa) initn: 44 init1: 44 opt: 83 Z-score: 96.1 bits: 27.1 E(): 3.8 Smith-Waterman score: 83; 25.166% identity (50.993% similar) in 151 aa overlap (160-305:211-349) 130 140 150 160 170 180 FLJ000 SRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREIINTYTEAVQTVDPFKATGKPHTLW :: . .: :..:.. .: .. . KIAA19 EDDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALE-IDKQNVEA-----L 190 200 210 220 230 190 200 210 220 230 240 FLJ000 VAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQC-----GELELRHENYDEAL :: . .: .:.:. : .: : . : . . :: :.:: ..:.. .: KIAA19 VARGALYATKGSLNKAIEDFELALE-NCPTHRNARKYLCQTLVERGGQLE-EEEKFLNAE 240 250 260 270 280 290 250 260 270 280 290 300 FLJ000 RLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDL .:: :: . :. . ... . :::.. :. ::. :.:: . : KIAA19 SYYKKALALDETFKDAEDALQKLHKYMQKSLELREKQAEKEEK----QKTKKIETSAEKL 300 310 320 330 340 310 320 330 FLJ000 RIATPQIVINYAMFLEEHKYFEESFKVRG : KIAA19 RKLLKEEKRLKKKRRKSTSSSSVSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRR 350 360 370 380 390 400 >>KIAA0733 ( 698 res) hk03729s1 (698 aa) initn: 36 init1: 36 opt: 82 Z-score: 94.6 bits: 26.9 E(): 4.5 Smith-Waterman score: 82; 19.892% identity (51.075% similar) in 186 aa overlap (55-228:500-675) 30 40 50 60 70 80 FLJ000 KVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFT :.:... .... : . . .: .. KIAA07 KITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLS 470 480 490 500 510 520 90 100 110 120 130 140 FLJ000 QVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLR-- . :. : . ..... . .: :: ::.. ....: :. . :.. : KIAA07 MGSDD-AAYTQALLVHQKARMERLQRE------LEIQKKKLDKLKSEVNEMENNLTRRRL 530 540 550 560 570 580 150 160 170 180 190 200 FLJ000 QNPHHVHEWHKRVALHQGRP--REIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNG . . . . . ..: : :.. .. .: :.: : :: :. .::.. : KIAA07 KRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARG-PHFNPSAIHNFYDNIG 590 600 610 620 630 640 210 220 230 240 250 FLJ000 -------QLDDARVILEKATKVNFKQVDDLASVW-CQCGELELRHENYDEALRLLRKATA . : : :. :. :.. . :: .. : : KIAA07 FVGPVPPKPKDQRSII-KTPKTQDTE-DDEGAQWNCTACTFLNHPALIRCEQCEMPRHF 650 660 670 680 690 260 270 280 290 300 310 FLJ000 LPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIV >>KIAA1961 ( 943 res) hk07733 (943 aa) initn: 36 init1: 36 opt: 82 Z-score: 93.1 bits: 27.1 E(): 5.5 Smith-Waterman score: 82; 25.000% identity (53.448% similar) in 116 aa overlap (133-244:230-339) 110 120 130 140 150 160 FLJ000 ETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRP : :...:: .:. : : . .:.: KIAA19 SGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLT----NHL-AWVPTV-MPNGQP 200 210 220 230 240 250 170 180 190 200 210 220 FLJ000 REIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQ-LDDARVILEKATKVNFKQVD : .. :.:: . : . ::. .. .: :. . ::... . ... KIAA19 PIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLL 260 270 280 290 300 310 230 240 250 260 270 FLJ000 DLASVWCQCGELELRH--EN-YDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVW . . . .:.::. : :: :::. KIAA19 YFLTYFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLL 320 330 340 350 360 370 >>KIAA0251 ( 820 res) ha07028 (820 aa) initn: 76 init1: 50 opt: 81 Z-score: 92.7 bits: 26.8 E(): 5.8 Smith-Waterman score: 81; 28.889% identity (56.667% similar) in 90 aa overlap (102-188:638-720) 80 90 100 110 120 130 FLJ000 EAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELGREEEDDVDLELRLARFEQLISR .:. .:. :. .....::. : :.: KIAA02 VGMASDNVDAAELVETIAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERL--- 610 620 630 640 650 660 140 150 160 170 180 FLJ000 RPLLLNSVLLRQNP--HHVHEWHKRV-ALHQGRPREIINTYTEAVQTVDPFKATGKPHTL :. .::: : : .: . : ::..:: .. :... . .:: : :: KIAA02 ----LEEGVLRQIPVVGSVLNWFSPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTL 670 680 690 700 710 720 190 200 210 220 230 240 FLJ000 WVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEALRLLR KIAA02 PPTPSGSRTKQRLPGQKPFKRSLRGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASS 730 740 750 760 770 780 >>KIAA1874 ( 579 res) hk07257s1 (579 aa) initn: 42 init1: 42 opt: 79 Z-score: 92.2 bits: 26.2 E(): 6.2 Smith-Waterman score: 79; 26.357% identity (51.938% similar) in 129 aa overlap (197-322:115-230) 170 180 190 200 210 220 FLJ000 NTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDAR--VILEKATKVNFKQVDDLA :. :.:: :. :.:: :.. .:. KIAA18 TEEGEVAALRLTARSQETVTFKDVAMDFTPEEWGKLDPAQRDVMLE-----NYR---NLV 90 100 110 120 130 230 240 250 260 270 280 FLJ000 SVWCQCGELELRH-ENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLAD :.: .. : .. :: : :.: ::: : .. : : :.. :.. .: . KIAA18 SLWLPVSKPESHNLENGKEPLKLERKA---P--KSSYSDMETRPQSKDSTSVQDFSKAES 140 150 160 170 180 190 290 300 310 320 330 FLJ000 LEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKVRG . .. . ..::: :. . . . : :.: KIAA18 CKVAIIDRLTRNSVYDSNLEAALECENWLENQQGNQERHLREMFTHMNSLSEETDHKHDV 200 210 220 230 240 250 KIAA18 YWKSFNQKSVLITEDRVPKGSYAFHTLEKSLKQKSNLMKKQRTYKEKKPHKCNDCGELFT 260 270 280 290 300 310 >>KIAA1767 ( 1960 res) eg01735 (1960 aa) initn: 60 init1: 60 opt: 84 Z-score: 91.6 bits: 27.8 E(): 6.6 Smith-Waterman score: 84; 31.034% identity (52.874% similar) in 87 aa overlap (97-175:1681-1761) 70 80 90 100 110 120 FLJ000 RDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASELG-REEEDDVDLELRLARF .:::... .: :: . : ::: KIAA17 NERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVV 1660 1670 1680 1690 1700 1710 130 140 150 160 170 FLJ000 EQLISRRPLLLNSVLLRQNPHHVHE-------WHKRVALHQGRPREIINTYTEAVQTVDP : : : ::.:. ::: . : :. ..: :.. . . .. ::.: : KIAA17 EVLTSTTPLFLT------NPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMS 1720 1730 1740 1750 1760 180 190 200 210 220 230 FLJ000 FKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHE KIAA17 QENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILLGWLLGESDDLVACV 1770 1780 1790 1800 1810 1820 333 residues in 1 query sequences 2210661 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:32:49 2009 done: Fri Feb 27 10:32:50 2009 Total Scan time: 0.470 Total Display time: 0.080 Function used was FASTA [version 34.26.5 April 26, 2007]