# /usr/local/bin/fasta34_t -T 8 -b50 -d10 -E0.01 -H -O./tmp/as00090.fasta.nr -Q ../query/FLJ00090.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00090, 770 aa vs /cdna2/lib/nr/nr library 2693465022 residues in 7827732 sequences statistics sampled from 60000 to 7813114 sequences Expectation_n fit: rho(ln(x))= 6.9975+/-0.000209; mu= 5.7463+/- 0.012 mean_var=152.2773+/-29.447, 0's: 30 Z-trim: 60 B-trim: 360 in 1/65 Lambda= 0.103934 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 38, opt: 26, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7827732) gi|18676424|dbj|BAB84864.1| FLJ00090 protein [Homo ( 770) 5177 788.4 0 gi|122937241|ref|NP_001073889.1| SH3 and multiple (1747) 5177 788.8 0 gi|194305995|dbj|BAG55459.1| SH3 and multiple anky (1731) 5111 778.9 0 gi|194680947|ref|XP_589942.4| PREDICTED: similar t (1986) 4888 745.5 4.6e-212 gi|71725080|dbj|BAE16756.1| Shank3 [Mus musculus] (1730) 4866 742.1 4.1e-211 gi|148841191|sp|Q4ACU6.2|SHAN3_MOUSE RecName: Full (1805) 4866 742.1 4.3e-211 gi|149017576|gb|EDL76580.1| rCG59239, isoform CRA_ (1203) 4849 739.4 1.9e-210 gi|5262748|emb|CAB45688.1| Proline rich synapse as (1806) 4849 739.6 2.5e-210 gi|22001983|sp|Q9JLU4.2|SHAN3_RAT RecName: Full=SH (1815) 4170 637.8 1.1e-179 gi|7381056|gb|AAF61375.1|AF133301_1 Shank postsyna (1740) 4129 631.6 7.7e-178 gi|148887434|sp|Q9BYB0.2|SHAN3_HUMAN RecName: Full (1741) 3933 602.2 5.4e-169 gi|119593992|gb|EAW73586.1| hCG1987869, isoform CR (1709) 3856 590.7 1.6e-165 gi|194227028|ref|XP_001914989.1| PREDICTED: SH3 an (1519) 3641 558.4 7.4e-156 gi|119593991|gb|EAW73585.1| hCG1987869, isoform CR ( 538) 3597 551.4 3.4e-154 gi|149017575|gb|EDL76579.1| rCG59239, isoform CRA_ (1023) 3574 548.2 5.9e-153 gi|126339033|ref|XP_001366729.1| PREDICTED: simila (2020) 2656 410.8 2.6e-111 gi|38649051|gb|AAH62987.1| SHANK3 protein [Homo sa ( 395) 2257 350.3 8.2e-94 gi|149435862|ref|XP_001520873.1| PREDICTED: simila ( 964) 2102 327.4 1.6e-86 gi|73968799|ref|XP_848271.1| PREDICTED: similar to (1541) 1635 257.6 2.6e-65 gi|47216040|emb|CAG11371.1| unnamed protein produc (1125) 1283 204.7 1.6e-49 gi|220678846|emb|CAK11335.2| novel protein similar (1352) 1064 171.9 1.4e-39 gi|94734035|emb|CAK11480.1| novel protein similar (1466) 1063 171.8 1.7e-39 gi|5381428|gb|AAD42976.1|AF159047_1 SPANK-2 [Rattu ( 905) 996 161.6 1.2e-36 gi|123231811|emb|CAI20675.2| novel protein similar (1601) 890 145.9 1.1e-31 gi|189518059|ref|XP_001919745.1| PREDICTED: simila (1631) 890 145.9 1.2e-31 gi|126343432|ref|XP_001381030.1| PREDICTED: simila (1086) 659 111.1 2.3e-21 gi|194679933|ref|XP_876072.3| PREDICTED: similar t (1837) 658 111.2 3.8e-21 gi|149061805|gb|EDM12228.1| rCG47889, isoform CRA_ ( 853) 641 108.3 1.3e-20 gi|118091441|ref|XP_426415.2| PREDICTED: similar t (1770) 638 108.2 2.9e-20 gi|114639034|ref|XP_522093.2| PREDICTED: SH3 and m (1091) 630 106.8 4.7e-20 gi|114639032|ref|XP_001174048.1| PREDICTED: SH3 an (1254) 630 106.8 5.2e-20 gi|119595178|gb|EAW74772.1| SH3 and multiple ankyr (1088) 628 106.5 5.8e-20 gi|119595181|gb|EAW74775.1| SH3 and multiple ankyr (1153) 628 106.5 6.1e-20 gi|22001987|sp|Q9UPX8.2|SHAN2_HUMAN RecName: Full= (1253) 628 106.5 6.4e-20 gi|195934811|gb|AAI68372.1| SH3 and multiple ankyr (1254) 628 106.5 6.4e-20 gi|119595177|gb|EAW74771.1| SH3 and multiple ankyr (1657) 628 106.6 7.9e-20 gi|109105111|ref|XP_001099714.1| PREDICTED: simila (1248) 625 106.1 8.8e-20 gi|109105109|ref|XP_001099919.1| PREDICTED: simila (1254) 625 106.1 8.8e-20 gi|109105113|ref|XP_001099818.1| PREDICTED: simila (1269) 625 106.1 8.9e-20 gi|149409600|ref|XP_001507367.1| PREDICTED: simila (1367) 622 105.7 1.3e-19 gi|73983555|ref|XP_540798.2| PREDICTED: similar to (1938) 622 105.8 1.6e-19 gi|148686297|gb|EDL18244.1| mCG142121 [Mus musculu (1652) 605 103.2 8.6e-19 gi|47210708|emb|CAF90000.1| unnamed protein produc (1448) 604 103.0 8.7e-19 gi|189442053|gb|AAI67171.1| SH3/ankyrin domain gen (1262) 603 102.8 8.7e-19 gi|164607122|ref|NP_001074839.2| SH3/ankyrin domai (1262) 602 102.6 9.7e-19 gi|149061807|gb|EDM12230.1| rCG47889, isoform CRA_ (1009) 600 102.2 1e-18 gi|149061806|gb|EDM12229.1| rCG47889, isoform CRA_ (1025) 600 102.3 1e-18 gi|169403965|ref|NP_001106844.2| SH3/ankyrin domai (1472) 602 102.7 1.1e-18 gi|81895462|sp|Q80Z38.1|SHAN2_MOUSE RecName: Full= (1476) 602 102.7 1.1e-18 gi|4995819|emb|CAB44314.1| proline rich synapse as (1250) 600 102.3 1.2e-18 >>gi|18676424|dbj|BAB84864.1| FLJ00090 protein [Homo sap (770 aa) initn: 5177 init1: 5177 opt: 5177 Z-score: 4202.9 bits: 788.4 E(): 0 Smith-Waterman score: 5177; 100.000% identity (100.000% similar) in 770 aa overlap (1-770:1-770) 10 20 30 40 50 60 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 DAQERAALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAFGGPGPAKDRRLE 10 20 30 40 50 60 70 80 90 100 110 120 FLJ000 ERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTGPTAGRDLLLPSPVSALKPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 ERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTGPTAGRDLLLPSPVSALKPLV 70 80 90 100 110 120 130 140 150 160 170 180 FLJ000 SGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDADRPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 SGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDADRPGP 130 140 150 160 170 180 190 200 210 220 230 240 FLJ000 LFVDVQARDPERGSLASPAFSPRSPAWIPVPARREAEKVPREERKSPEDKKSMILSVLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 LFVDVQARDPERGSLASPAFSPRSPAWIPVPARREAEKVPREERKSPEDKKSMILSVLDT 190 200 210 220 230 240 250 260 270 280 290 300 FLJ000 SLQRPAGLIVVHATSNGQEPSRLGGAEEERPGTPELAPAPMQSAAVAEPLPSPRAQPPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 SLQRPAGLIVVHATSNGQEPSRLGGAEEERPGTPELAPAPMQSAAVAEPLPSPRAQPPGG 250 260 270 280 290 300 310 320 330 340 350 360 FLJ000 TPADAGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 TPADAGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLAT 310 320 330 340 350 360 370 380 390 400 410 420 FLJ000 PLAGPGPSPTTVPSPASGKPSSEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 PLAGPGPSPTTVPSPASGKPSSEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSS 370 380 390 400 410 420 430 440 450 460 470 480 FLJ000 MSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 MSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSE 430 440 450 460 470 480 490 500 510 520 530 540 FLJ000 LMAQQHHAASAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVISELSSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 LMAQQHHAASAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVISELSSRL 490 500 510 520 530 540 550 560 570 580 590 600 FLJ000 QQLNKDTRSLGEEPVGGLGSLLDPAKKSPIAAARLFSSLGELSSISAQRSPGGPGGGASY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 QQLNKDTRSLGEEPVGGLGSLLDPAKKSPIAAARLFSSLGELSSISAQRSPGGPGGGASY 550 560 570 580 590 600 610 620 630 640 650 660 FLJ000 SVRPSGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 SVRPSGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPK 610 620 630 640 650 660 670 680 690 700 710 720 FLJ000 EVRFVVRSVSARSRSPSPSPLPSPASGPGPGAPGPRRPFQQKPLQLWSKFDVGDWLESIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 EVRFVVRSVSARSRSPSPSPLPSPASGPGPGAPGPRRPFQQKPLQLWSKFDVGDWLESIH 670 680 690 700 710 720 730 740 750 760 770 FLJ000 LGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVGHRMNIERALRQLDGS :::::::::::::::::::::::::::::::::::::::::::::::::: gi|186 LGEHRDRFEDHEIEGAHLPALTKDDFVELGVTRVGHRMNIERALRQLDGS 730 740 750 760 770 >>gi|122937241|ref|NP_001073889.1| SH3 and multiple anky (1747 aa) initn: 5177 init1: 5177 opt: 5177 Z-score: 4198.3 bits: 788.8 E(): 0 Smith-Waterman score: 5177; 100.000% identity (100.000% similar) in 770 aa overlap (1-770:978-1747) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG :::::::::::::::::::::::::::::: gi|122 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPGGGSFAREPSPTHRG 950 960 970 980 990 1000 40 50 60 70 80 90 FLJ000 PRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 PRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSR 1010 1020 1030 1040 1050 1060 100 110 120 130 140 150 FLJ000 SIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 SIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALA 1070 1080 1090 1100 1110 1120 160 170 180 190 200 210 FLJ000 LAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 LAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPV 1130 1140 1150 1160 1170 1180 220 230 240 250 260 270 FLJ000 PARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 PARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEEER 1190 1200 1210 1220 1230 1240 280 290 300 310 320 330 FLJ000 PGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 PGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQLS 1250 1260 1270 1280 1290 1300 340 350 360 370 380 390 FLJ000 SSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 SSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAPES 1310 1320 1330 1340 1350 1360 400 410 420 430 440 450 FLJ000 AADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 AADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPP 1370 1380 1390 1400 1410 1420 460 470 480 490 500 510 FLJ000 VPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQRRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 VPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQRRS 1430 1440 1450 1460 1470 1480 520 530 540 550 560 570 FLJ000 KLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 KLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPI 1490 1500 1510 1520 1530 1540 580 590 600 610 620 630 FLJ000 AAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 AAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLG 1550 1560 1570 1580 1590 1600 640 650 660 670 680 690 FLJ000 AGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 AGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGPGP 1610 1620 1630 1640 1650 1660 700 710 720 730 740 750 FLJ000 GAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|122 GAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELG 1670 1680 1690 1700 1710 1720 760 770 FLJ000 VTRVGHRMNIERALRQLDGS :::::::::::::::::::: gi|122 VTRVGHRMNIERALRQLDGS 1730 1740 >>gi|194305995|dbj|BAG55459.1| SH3 and multiple ankyrin (1731 aa) initn: 3367 init1: 3367 opt: 5111 Z-score: 4144.9 bits: 778.9 E(): 0 Smith-Waterman score: 5111; 98.831% identity (99.740% similar) in 770 aa overlap (1-770:963-1731) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG :::::::::::::::::::::::::::::: gi|194 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPGGGSFAREPSPTHRG 940 950 960 970 980 990 40 50 60 70 80 90 FLJ000 PRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSR :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: gi|194 PRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPSADLPSLQPSR 1000 1010 1020 1030 1040 1050 100 110 120 130 140 150 FLJ000 SIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALA :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: gi|194 SIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPTLGPSGSTFIHPLTGKPLDPSSPLALA 1060 1070 1080 1090 1100 1110 160 170 180 190 200 210 FLJ000 LAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 LAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPV 1120 1130 1140 1150 1160 1170 220 230 240 250 260 270 FLJ000 PARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEEER ::::::::.::::::::::::::::::::::::::::::::::::::::::::: ::::: gi|194 PARREAEKAPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLG-AEEER 1180 1190 1200 1210 1220 1230 280 290 300 310 320 330 FLJ000 PGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQLS :::::::::::::::::::::::::::::.:::. ::::::::::::::::::::::::: gi|194 PGTPELAPAPMQSAAVAEPLPSPRAQPPGSTPAEPGPGQGSSEEEPELVFAVNLPPAQLS 1240 1250 1260 1270 1280 1290 340 350 360 370 380 390 FLJ000 SSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 SSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAPES 1300 1310 1320 1330 1340 1350 400 410 420 430 440 450 FLJ000 AADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 AADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPP 1360 1370 1380 1390 1400 1410 460 470 480 490 500 510 FLJ000 VPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQRRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 VPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQRRS 1420 1430 1440 1450 1460 1470 520 530 540 550 560 570 FLJ000 KLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPI :::::::::::::::::::::::::::::::::::::::::::::::::.::::.::::: gi|194 KLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGGLLDPVKKSPI 1480 1490 1500 1510 1520 1530 580 590 600 610 620 630 FLJ000 AAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 AAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLG 1540 1550 1560 1570 1580 1590 640 650 660 670 680 690 FLJ000 AGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 AGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGPGP 1600 1610 1620 1630 1640 1650 700 710 720 730 740 750 FLJ000 GAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 GAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVELG 1660 1670 1680 1690 1700 1710 760 770 FLJ000 VTRVGHRMNIERALRQLDGS :::::::::::::::::::: gi|194 VTRVGHRMNIERALRQLDGS 1720 1730 >>gi|194680947|ref|XP_589942.4| PREDICTED: similar to pr (1986 aa) initn: 2596 init1: 2523 opt: 4888 Z-score: 3963.4 bits: 745.5 E(): 4.6e-212 Smith-Waterman score: 4888; 94.560% identity (97.668% similar) in 772 aa overlap (1-770:1216-1986) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: ::::::::::::: gi|194 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVVGSFAREPSPTHRG 1190 1200 1210 1220 1230 1240 40 50 60 70 80 90 FLJ000 PRPGGLDYGAGDGPGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSR :::.::::: :::::::::::.:.::::::::::::::::::::::..:.::.::::::: gi|194 PRPSGLDYGPGDGPGLAFGGPAPSKDRRLEERRRSTVFLSVGAIEGASPSADMPSLQPSR 1250 1260 1270 1280 1290 1300 100 110 120 130 140 FLJ000 SIDERLLGTGPT-AGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLAL :::::::: : : .:::::::::::::::::::::::::::::::::::::::::::::: gi|194 SIDERLLGPGATITGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLAL 1310 1320 1330 1340 1350 1360 150 160 170 180 190 200 FLJ000 ALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIP :::::::::::::::::::::::::.:::::::::::::: ::: :::::::::::::.: gi|194 ALAARERALASQAPSRSPTPVHSPDTDRPGPLFVDVQARDSERGPLASPAFSPRSPAWVP 1370 1380 1390 1400 1410 1420 210 220 230 240 250 260 FLJ000 VPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEEE :::::: :::::::::::::::::::::::::::::::::::::::::.::: :: :::. gi|194 VPARREPEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGHEPSGLG-AEEQ 1430 1440 1450 1460 1470 1480 270 280 290 300 310 320 FLJ000 RPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQL ::::::::::: :::.::::::::::::::..:.: :::::::::::::::::::::::: gi|194 RPGTPELAPAPTQSAVVAEPLPSPRAQPPGSAPTDPGPGQGSSEEEPELVFAVNLPPAQL 1490 1500 1510 1520 1530 1540 330 340 350 360 370 380 FLJ000 SSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAPE ::::::::::::::::::::::::::::::::: ::::::::::.::::::::::::::: gi|194 SSSDEETREELARIGLVPPPEEFANGVLLATPLPGPGPSPTTVPGPASGKPSSEPPPAPE 1550 1560 1570 1580 1590 1600 390 400 410 420 430 440 FLJ000 SAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 SAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKP 1610 1620 1630 1640 1650 1660 450 460 470 480 490 500 FLJ000 PVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQRR ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: gi|194 PVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAATAGLASAAGPARPRYLFQRR 1670 1680 1690 1700 1710 1720 510 520 530 540 550 560 FLJ000 SKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSP ::::::::::::::::::::::::.::::::::::::::::::::.::::.::::::::: gi|194 SKLWGDPVESRGLPGPEDDKPTVITELSSRLQQLNKDTRSLGEEPAGGLGGLLDPAKKSP 1730 1740 1750 1760 1770 1780 570 580 590 600 610 620 FLJ000 IAAARLFSSLGELSSISAQ-RSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG ::::::::::::::.:::: :::::::::::: :::.::::::::::::::::::::::: gi|194 IAAARLFSSLGELSTISAQQRSPGGPGGGASYPVRPGGRYPVARRAPSPVKPASLERVEG 1790 1800 1810 1820 1830 1840 630 640 650 660 670 680 FLJ000 LGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGP ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: :: gi|194 LGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSLSPLPSPAPGP 1850 1860 1870 1880 1890 1900 690 700 710 720 730 740 FLJ000 GPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVE :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 GPGAPSPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVE 1910 1920 1930 1940 1950 1960 750 760 770 FLJ000 LGVTRVGHRMNIERALRQLDGS :::::::::::::::::::::: gi|194 LGVTRVGHRMNIERALRQLDGS 1970 1980 >>gi|71725080|dbj|BAE16756.1| Shank3 [Mus musculus] (1730 aa) initn: 4207 init1: 2734 opt: 4866 Z-score: 3946.3 bits: 742.1 E(): 4.1e-211 Smith-Waterman score: 4866; 94.560% identity (97.539% similar) in 772 aa overlap (1-770:961-1730) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: :::::::::::::: gi|717 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVGGSFAREPSPTHRG 940 950 960 970 980 990 40 50 60 70 80 FLJ000 PRPGGLDYGAGDGPGLAFGGP--GPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQP ::::.:::..:.: ::.:::: ::.:.::::::::::::::::::::: :.:::::::: gi|717 PRPGSLDYSSGEGLGLTFGGPSPGPVKERRLEERRRSTVFLSVGAIEGSPPSADLPSLQP 1000 1010 1020 1030 1040 1050 90 100 110 120 130 140 FLJ000 SRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLA :::::::::::: :.:::::::::::::::::.::::::::::::::::::::::::::: gi|717 SRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLA 1060 1070 1080 1090 1100 1110 150 160 170 180 190 200 FLJ000 LALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWI :::::::::::::.::::::::::::::::::::::::.:: ::: :::::::::::::: gi|717 LALAARERALASQTPSRSPTPVHSPDADRPGPLFVDVQTRDSERGPLASPAFSPRSPAWI 1120 1130 1140 1150 1160 1170 210 220 230 240 250 260 FLJ000 PVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEE :::::::::: ::::::::::::::::::::::::::::::::::::::::::::: ::: gi|717 PVPARREAEKPPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLG-AEE 1180 1190 1200 1210 1220 270 280 290 300 310 320 FLJ000 ERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQ ::::::::::::::.::::::.:::::::::. ::: ::::::::::::::::::::::: gi|717 ERPGTPELAPAPMQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQ 1230 1240 1250 1260 1270 1280 330 340 350 360 370 380 FLJ000 LSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAP :::::::::::::::::::::::::::.::.:: :::: ::::::::::::::: :::: gi|717 LSSSDEETREELARIGLVPPPEEFANGILLTTPPPGPGPLPTTVPSPASGKPSSELPPAP 1290 1300 1310 1320 1330 1340 390 400 410 420 430 440 FLJ000 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|717 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK 1350 1360 1370 1380 1390 1400 450 460 470 480 490 500 FLJ000 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQR ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: gi|717 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASTGLASAAGPARPRYLFQR 1410 1420 1430 1440 1450 1460 510 520 530 540 550 560 FLJ000 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|717 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 1470 1480 1490 1500 1510 1520 570 580 590 600 610 620 FLJ000 PIAAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: gi|717 PIAAARLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG 1530 1540 1550 1560 1570 1580 630 640 650 660 670 680 FLJ000 LGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGP ::::.:::::::::::::::::::::::::::::::::::::::::::::::::::. : gi|717 LGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPSPGS 1590 1600 1610 1620 1630 1640 690 700 710 720 730 740 FLJ000 GPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVE ::.: ::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|717 GPSA-GPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKEDFVE 1650 1660 1670 1680 1690 1700 750 760 770 FLJ000 LGVTRVGHRMNIERALRQLDGS :::::::::::::::::::::: gi|717 LGVTRVGHRMNIERALRQLDGS 1710 1720 1730 >>gi|148841191|sp|Q4ACU6.2|SHAN3_MOUSE RecName: Full=SH3 (1805 aa) initn: 4207 init1: 2734 opt: 4866 Z-score: 3946.1 bits: 742.1 E(): 4.3e-211 Smith-Waterman score: 4866; 94.560% identity (97.539% similar) in 772 aa overlap (1-770:1036-1805) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: :::::::::::::: gi|148 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVGGSFAREPSPTHRG 1010 1020 1030 1040 1050 1060 40 50 60 70 80 FLJ000 PRPGGLDYGAGDGPGLAFGGP--GPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQP ::::.:::..:.: ::.:::: ::.:.::::::::::::::::::::: :.:::::::: gi|148 PRPGSLDYSSGEGLGLTFGGPSPGPVKERRLEERRRSTVFLSVGAIEGSPPSADLPSLQP 1070 1080 1090 1100 1110 1120 90 100 110 120 130 140 FLJ000 SRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLA :::::::::::: :.:::::::::::::::::.::::::::::::::::::::::::::: gi|148 SRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLA 1130 1140 1150 1160 1170 1180 150 160 170 180 190 200 FLJ000 LALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWI :::::::::::::.::::::::::::::::::::::::.:: ::: :::::::::::::: gi|148 LALAARERALASQTPSRSPTPVHSPDADRPGPLFVDVQTRDSERGPLASPAFSPRSPAWI 1190 1200 1210 1220 1230 1240 210 220 230 240 250 260 FLJ000 PVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEE :::::::::: ::::::::::::::::::::::::::::::::::::::::::::: ::: gi|148 PVPARREAEKPPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLG-AEE 1250 1260 1270 1280 1290 1300 270 280 290 300 310 320 FLJ000 ERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQ ::::::::::::::.::::::.:::::::::. ::: ::::::::::::::::::::::: gi|148 ERPGTPELAPAPMQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQ 1310 1320 1330 1340 1350 1360 330 340 350 360 370 380 FLJ000 LSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAP :::::::::::::::::::::::::::.::.:: :::: ::::::::::::::: :::: gi|148 LSSSDEETREELARIGLVPPPEEFANGILLTTPPPGPGPLPTTVPSPASGKPSSELPPAP 1370 1380 1390 1400 1410 1420 390 400 410 420 430 440 FLJ000 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK 1430 1440 1450 1460 1470 1480 450 460 470 480 490 500 FLJ000 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQR ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: gi|148 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASTGLASAAGPARPRYLFQR 1490 1500 1510 1520 1530 1540 510 520 530 540 550 560 FLJ000 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 1550 1560 1570 1580 1590 1600 570 580 590 600 610 620 FLJ000 PIAAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: gi|148 PIAAARLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG 1610 1620 1630 1640 1650 1660 630 640 650 660 670 680 FLJ000 LGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGP ::::.:::::::::::::::::::::::::::::::::::::::::::::::::::. : gi|148 LGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPSPGS 1670 1680 1690 1700 1710 1720 690 700 710 720 730 740 FLJ000 GPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVE ::.: ::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|148 GPSA-GPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKEDFVE 1730 1740 1750 1760 1770 1780 750 760 770 FLJ000 LGVTRVGHRMNIERALRQLDGS :::::::::::::::::::::: gi|148 LGVTRVGHRMNIERALRQLDGS 1790 1800 >>gi|149017576|gb|EDL76580.1| rCG59239, isoform CRA_b [R (1203 aa) initn: 4182 init1: 2724 opt: 4849 Z-score: 3934.6 bits: 739.4 E(): 1.9e-210 Smith-Waterman score: 4849; 94.171% identity (97.409% similar) in 772 aa overlap (1-770:434-1203) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: :::::::::::::: gi|149 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVGGSFAREPSPTHRG 410 420 430 440 450 460 40 50 60 70 80 FLJ000 PRPGGLDYGAGDGPGLAFGGP--GPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQP ::::::::..:.: ::.:::: ::.:.::::::::::::::::::::: :.:::::::: gi|149 PRPGGLDYSSGEGLGLTFGGPSPGPVKERRLEERRRSTVFLSVGAIEGSPPSADLPSLQP 470 480 490 500 510 520 90 100 110 120 130 140 FLJ000 SRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLA :::::::::::: :.:::::::::::::::::.::::::::::::::::::::::::::: gi|149 SRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLA 530 540 550 560 570 580 150 160 170 180 190 200 FLJ000 LALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWI :::::::::::::.::::::::::::::::::::::::.:: ::: :::::::::::::: gi|149 LALAARERALASQTPSRSPTPVHSPDADRPGPLFVDVQTRDSERGPLASPAFSPRSPAWI 590 600 610 620 630 640 210 220 230 240 250 260 FLJ000 PVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEE :::::::::: ::::::::::::::::::::::::::::::::::::::::.::: ::: gi|149 PVPARREAEKPTREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPNRLG-AEE 650 660 670 680 690 700 270 280 290 300 310 320 FLJ000 ERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQ ::::::::::.:::.::::::.:::::::::. ::: ::::::::::::::::::::::: gi|149 ERPGTPELAPTPMQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQ 710 720 730 740 750 760 330 340 350 360 370 380 FLJ000 LSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAP :::::::::::::::::::::::::::.::::: :::: ::::::::::::::: :::: gi|149 LSSSDEETREELARIGLVPPPEEFANGILLATPPPGPGPLPTTVPSPASGKPSSELPPAP 770 780 790 800 810 820 390 400 410 420 430 440 FLJ000 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK 830 840 850 860 870 880 450 460 470 480 490 500 FLJ000 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQR ::::::::::::::::::::::::::::::::::::::::.:.::.:::::::::::::: gi|149 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHATSTGLTSAAGPARPRYLFQR 890 900 910 920 930 940 510 520 530 540 550 560 FLJ000 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 950 960 970 980 990 1000 570 580 590 600 610 620 FLJ000 PIAAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: gi|149 PIAAARLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG 1010 1020 1030 1040 1050 1060 630 640 650 660 670 680 FLJ000 LGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGP ::::.:::::::::::::::::::::::::::::::::::::::::::::::::::. : gi|149 LGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPSPGS 1070 1080 1090 1100 1110 1120 690 700 710 720 730 740 FLJ000 GPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVE ::.: ::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|149 GPSA-GPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKEDFVE 1130 1140 1150 1160 1170 1180 750 760 770 FLJ000 LGVTRVGHRMNIERALRQLDGS :::::::::::::::::::::: gi|149 LGVTRVGHRMNIERALRQLDGS 1190 1200 >>gi|5262748|emb|CAB45688.1| Proline rich synapse associ (1806 aa) initn: 4182 init1: 2724 opt: 4849 Z-score: 3932.3 bits: 739.6 E(): 2.5e-210 Smith-Waterman score: 4849; 94.171% identity (97.409% similar) in 772 aa overlap (1-770:1037-1806) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: :::::::::::::: gi|526 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVGGSFAREPSPTHRG 1010 1020 1030 1040 1050 1060 40 50 60 70 80 FLJ000 PRPGGLDYGAGDGPGLAFGGP--GPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQP ::::::::..:.: ::.:::: ::.:.::::::::::::::::::::: :.:::::::: gi|526 PRPGGLDYSSGEGLGLTFGGPSPGPVKERRLEERRRSTVFLSVGAIEGSPPSADLPSLQP 1070 1080 1090 1100 1110 1120 90 100 110 120 130 140 FLJ000 SRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLA :::::::::::: :.:::::::::::::::::.::::::::::::::::::::::::::: gi|526 SRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLA 1130 1140 1150 1160 1170 1180 150 160 170 180 190 200 FLJ000 LALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWI :::::::::::::.::::::::::::::::::::::::.:: ::: :::::::::::::: gi|526 LALAARERALASQTPSRSPTPVHSPDADRPGPLFVDVQTRDSERGPLASPAFSPRSPAWI 1190 1200 1210 1220 1230 1240 210 220 230 240 250 260 FLJ000 PVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEE :::::::::: ::::::::::::::::::::::::::::::::::::::::.::: ::: gi|526 PVPARREAEKPTREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPNRLG-AEE 1250 1260 1270 1280 1290 1300 270 280 290 300 310 320 FLJ000 ERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQ ::::::::::.:::.::::::.:::::::::. ::: ::::::::::::::::::::::: gi|526 ERPGTPELAPTPMQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQ 1310 1320 1330 1340 1350 1360 330 340 350 360 370 380 FLJ000 LSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAP :::::::::::::::::::::::::::.::::: :::: ::::::::::::::: :::: gi|526 LSSSDEETREELARIGLVPPPEEFANGILLATPPPGPGPLPTTVPSPASGKPSSELPPAP 1370 1380 1390 1400 1410 1420 390 400 410 420 430 440 FLJ000 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|526 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK 1430 1440 1450 1460 1470 1480 450 460 470 480 490 500 FLJ000 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQR ::::::::::::::::::::::::::::::::::::::::.:.::.:::::::::::::: gi|526 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHATSTGLTSAAGPARPRYLFQR 1490 1500 1510 1520 1530 1540 510 520 530 540 550 560 FLJ000 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|526 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 1550 1560 1570 1580 1590 1600 570 580 590 600 610 620 FLJ000 PIAAARLFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: gi|526 PIAAARLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEG 1610 1620 1630 1640 1650 1660 630 640 650 660 670 680 FLJ000 LGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPASGP ::::.:::::::::::::::::::::::::::::::::::::::::::::::::::. : gi|526 LGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLPSPSPGS 1670 1680 1690 1700 1710 1720 690 700 710 720 730 740 FLJ000 GPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKDDFVE ::.: ::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|526 GPSA-GPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLPALTKEDFVE 1730 1740 1750 1760 1770 1780 750 760 770 FLJ000 LGVTRVGHRMNIERALRQLDGS :::::::::::::::::::::: gi|526 LGVTRVGHRMNIERALRQLDGS 1790 1800 >>gi|22001983|sp|Q9JLU4.2|SHAN3_RAT RecName: Full=SH3 an (1815 aa) initn: 3635 init1: 1973 opt: 4170 Z-score: 3382.0 bits: 637.8 E(): 1.1e-179 Smith-Waterman score: 4821; 93.086% identity (96.287% similar) in 781 aa overlap (1-770:1037-1815) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: :::::::::::::: gi|220 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVGGSFAREPSPTHRG 1010 1020 1030 1040 1050 1060 40 50 60 70 80 FLJ000 PRPGGLDYGAGDGPGLAFGGP--GPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQP ::::::::..:.: ::.:::: ::.:.::::::::::::::::::::: :.:::::::: gi|220 PRPGGLDYSSGEGLGLTFGGPSPGPVKERRLEERRRSTVFLSVGAIEGSPPSADLPSLQP 1070 1080 1090 1100 1110 1120 90 100 110 120 130 140 FLJ000 SRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLA :::::::::::: :.:::::::::::::::::.::::::::::::::::::::::::::: gi|220 SRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPSLGPSGSTFIHPLTGKPLDPSSPLA 1130 1140 1150 1160 1170 1180 150 160 170 180 190 200 FLJ000 LALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWI :::::::::::::.::::::::::::::::::::::::.:: ::: :::::::::::::: gi|220 LALAARERALASQTPSRSPTPVHSPDADRPGPLFVDVQTRDSERGPLASPAFSPRSPAWI 1190 1200 1210 1220 1230 1240 210 220 230 240 250 260 FLJ000 PVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEE :::::::::: ::::::::::::::::::::::::::::::::::::::::.::: ::: gi|220 PVPARREAEKPTREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPNRLG-AEE 1250 1260 1270 1280 1290 1300 270 280 290 300 310 320 FLJ000 ERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQ ::::::::::.:::.::::::.:::::::::. ::: ::::::::::::::::::::::: gi|220 ERPGTPELAPTPMQAAAVAEPMPSPRAQPPGSIPADPGPGQGSSEEEPELVFAVNLPPAQ 1310 1320 1330 1340 1350 1360 330 340 350 360 370 380 FLJ000 LSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAP :::::::::::::::::::::::::::.::::: :::: ::::::::::::::: :::: gi|220 LSSSDEETREELARIGLVPPPEEFANGILLATPPPGPGPLPTTVPSPASGKPSSELPPAP 1370 1380 1390 1400 1410 1420 390 400 410 420 430 440 FLJ000 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK 1430 1440 1450 1460 1470 1480 450 460 470 480 490 500 FLJ000 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQR ::::::::::::::::::::::::::::::::::::::::.:.::.:::::::::::::: gi|220 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHATSTGLTSAAGPARPRYLFQR 1490 1500 1510 1520 1530 1540 510 520 530 540 550 560 FLJ000 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|220 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 1550 1560 1570 1580 1590 1600 570 580 590 600 610 FLJ000 PIAAAR---------LFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVK :::::: :::::::::.::::::::::::::::::::::::::::::::::: gi|220 PIAAARCAVVPSAGWLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVK 1610 1620 1630 1640 1650 1660 620 630 640 650 660 670 FLJ000 PASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPS :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: gi|220 PASLERVEGLGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPS 1670 1680 1690 1700 1710 1720 680 690 700 710 720 730 FLJ000 PLPSPASGPGPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLP :::::. : ::.: :::::::::::::::::::::::::::::::::::::::::::::: gi|220 PLPSPSPGSGPSA-GPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLP 1730 1740 1750 1760 1770 1780 740 750 760 770 FLJ000 ALTKDDFVELGVTRVGHRMNIERALRQLDGS ::::.:::::::::::::::::::::::::: gi|220 ALTKEDFVELGVTRVGHRMNIERALRQLDGS 1790 1800 1810 >>gi|7381056|gb|AAF61375.1|AF133301_1 Shank postsynaptic (1740 aa) initn: 3590 init1: 1943 opt: 4129 Z-score: 3349.0 bits: 631.6 E(): 7.7e-178 Smith-Waterman score: 4770; 91.933% identity (96.159% similar) in 781 aa overlap (1-770:962-1740) 10 20 30 FLJ000 DAQERAALAVGSPGPGGGSFAREPSPTHRG ::::::::::::::: :::::::::::::: gi|738 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPVGGSFAREPSPTHRG 940 950 960 970 980 990 40 50 60 70 80 FLJ000 PRPGGLDYGAGDGPGLAFGGP--GPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQP ::::::::..:.: ::.:::: ::.:.::::::::::::::::::::. :.:::::::: gi|738 PRPGGLDYSSGEGLGLTFGGPSPGPVKERRLEERRRSTVFLSVGAIEGNPPSADLPSLQP 1000 1010 1020 1030 1040 1050 90 100 110 120 130 140 FLJ000 SRSIDERLLGTGPTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLA :::::::::::: :.:::::::::::::::::.::.::::.::::::::::::::::::: gi|738 SRSIDERLLGTGATTGRDLLLPSPVSALKPLVGGPNLGPSSSTFIHPLTGKPLDPSSPLA 1060 1070 1080 1090 1100 1110 150 160 170 180 190 200 FLJ000 LALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWI :::::::::::::.::::::::::::::::::::::::.:: ::: :::::::::::::: gi|738 LALAARERALASQTPSRSPTPVHSPDADRPGPLFVDVQTRDSERGPLASPAFSPRSPAWI 1120 1130 1140 1150 1160 1170 210 220 230 240 250 260 FLJ000 PVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEE :::::::::: ::::::::::::::::::::::::::::::::::::::::.::: ::: gi|738 PVPARREAEKPTREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPNRLG-AEE 1180 1190 1200 1210 1220 1230 270 280 290 300 310 320 FLJ000 ERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPPAQ ::::::::::.:::.::::::.:::::::::. ::: ::.::.:::::.::::::::::: gi|738 ERPGTPELAPTPMQAAAVAEPMPSPRAQPPGNIPADPGPSQGNSEEEPKLVFAVNLPPAQ 1240 1250 1260 1270 1280 1290 330 340 350 360 370 380 FLJ000 LSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAP :::.:::::::::::::::::::::::.::::: :::: ::::::::::::::: :::: gi|738 LSSNDEETREELARIGLVPPPEEFANGILLATPPPGPGPLPTTVPSPASGKPSSELPPAP 1300 1310 1320 1330 1340 1350 390 400 410 420 430 440 FLJ000 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|738 ESAADSGVEEADTRSSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEK 1360 1370 1380 1390 1400 1410 450 460 470 480 490 500 FLJ000 PPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAGPARPRYLFQR ::::::::::::::::::::: ::::::::::::::::::.:.::.:::::::::::::: gi|738 PPVPPKPKLKSPLGKGPVTFRGPLLKQSSDSELMAQQHHATSTGLTSAAGPARPRYLFQR 1420 1430 1440 1450 1460 1470 510 520 530 540 550 560 FLJ000 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|738 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 1480 1490 1500 1510 1520 1530 570 580 590 600 610 FLJ000 PIAAAR---------LFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVK :::::: :::::::::.::::::::::::::::::::::::::::::::::: gi|738 PIAAARCAVVPSAGWLFSSLGELSTISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVK 1540 1550 1560 1570 1580 1590 620 630 640 650 660 670 FLJ000 PASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPS :::::::::::::.:::::::::::::::::::::::::::::::::::.:::::::::: gi|738 PASLERVEGLGAGVGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSASARSRSPSPS 1600 1610 1620 1630 1640 1650 680 690 700 710 720 730 FLJ000 PLPSPASGPGPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLP :::::. : ::.: :::::::::::::::::::::::::::::::::::::::::::::: gi|738 PLPSPSPGSGPSA-GPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIEGAHLP 1660 1670 1680 1690 1700 740 750 760 770 FLJ000 ALTKDDFVELGVTRVGHRMNIERALRQLDGS ::::.:::::::::::::::::::::::::: gi|738 ALTKEDFVELGVTRVGHRMNIERALRQLDGS 1710 1720 1730 1740 770 residues in 1 query sequences 2693465022 residues in 7827732 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 21:24:20 2009 done: Fri Feb 27 21:32:39 2009 Total Scan time: 1092.610 Total Display time: 0.470 Function used was FASTA [version 34.26.5 April 26, 2007]