# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh00608.fasta.huge -Q ../query/FLJ00352.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00352, 289 aa vs ./tmplib.10216 library 2210705 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 3.4482+/-0.00417; mu= 20.7614+/- 0.286 mean_var=103.8980+/-24.484, 0's: 0 Z-trim: 7 B-trim: 125 in 1/39 Lambda= 0.125826 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 36, opt: 24, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA0496 ( 218 res) hg00144 ( 218) 1137 216.0 1.4e-57 KIAA0222 ( 1204 res) ha02586 (1204) 125 33.7 0.06 KIAA1095 ( 1098 res) hk06736 (1098) 116 32.0 0.18 KIAA1588 ( 613 res) fj08823 ( 613) 112 30.8 0.23 KIAA1015 ( 841 res) hk03609(revised) ( 841) 112 31.1 0.26 KIAA1339 ( 409 res) fj00071 ( 409) 107 29.6 0.36 KIAA0426 ( 613 res) hh01274 ( 613) 108 30.1 0.38 KIAA1508 ( 573 res) hk06576 ( 573) 106 29.7 0.48 KIAA1285 ( 785 res) hh11563(revised) ( 785) 106 29.9 0.55 KIAA0326 ( 927 res) hg00579 ( 927) 106 30.1 0.59 KIAA1782 ( 545 res) aj00273 ( 545) 104 29.3 0.6 KIAA1198 ( 553 res) fg01911 ( 553) 101 28.7 0.88 KIAA2003 ( 460 res) ah02593 ( 460) 100 28.4 0.92 KIAA1948 ( 487 res) fh24556 ( 487) 98 28.1 1.2 KIAA1349 ( 752 res) fj00940 ( 752) 99 28.6 1.3 KIAA0628 ( 540 res) hh01433 ( 540) 95 27.6 1.9 KIAA1396 ( 551 res) hj08221 ( 551) 94 27.5 2.1 KIAA1956 ( 680 res) fk08713 ( 680) 94 27.6 2.3 KIAA1947 ( 608 res) fh23660 ( 608) 93 27.4 2.5 FLJ00284 ( 366 res) sh02281 ( 366) 91 26.6 2.6 KIAA1871 ( 821 res) hj05256s1 ( 821) 93 27.6 2.9 KIAA1874 ( 579 res) hk07257s1 ( 579) 91 27.0 3.2 KIAA0462 ( 2276 res) hg00891 (2276) 95 28.8 3.5 KIAA1559 ( 544 res) fh19195 ( 544) 90 26.7 3.5 KIAA0489 ( 192 res) hg01128 ( 192) 86 25.1 3.7 KIAA0760 ( 1224 res) hk04642s1 (1224) 92 27.7 3.9 KIAA0961 ( 530 res) hj05830 ( 530) 89 26.5 3.9 KIAA0798 ( 682 res) hk06584 ( 682) 89 26.7 4.4 KIAA1962 ( 746 res) hm00158 ( 746) 88 26.6 5.2 KIAA1615 ( 484 res) fj13419 ( 484) 86 25.9 5.5 KIAA0789 ( 620 res) pj01253 ( 620) 86 26.1 6.1 KIAA1710 ( 515 res) fj18457 ( 515) 85 25.8 6.4 KIAA1806 ( 481 res) fk00438 ( 481) 84 25.5 7 FLJ00107 ( 1234 res) as00107 (1234) 86 26.7 8.2 KIAA0680 ( 635 res) hk02746 ( 635) 83 25.6 9 KIAA0296 ( 1838 res) hf00260 (1838) 86 27.0 9.8 KIAA0412 ( 720 res) hg03242 ( 720) 82 25.5 11 KIAA0391 ( 571 res) hj00118 ( 571) 81 25.1 11 KIAA1084 ( 778 res) hj07515 ( 778) 82 25.6 11 KIAA1954 ( 468 res) fk02322 ( 468) 80 24.8 12 KIAA1675 ( 1286 res) ae00102 (1286) 83 26.2 12 FLJ00334 ( 645 res) sj04320 ( 645) 80 25.0 13 KIAA2007 ( 580 res) fj01689 ( 580) 79 24.8 14 KIAA0048 ( 627 res) ha01311 ( 627) 79 24.8 15 KIAA1141 ( 914 res) hk01833 ( 914) 80 25.3 15 KIAA0183 ( 1111 res) ha02726 (1111) 80 25.5 17 KIAA0065 ( 848 res) ha00946 ( 848) 78 24.9 19 KIAA0898 ( 979 res) hk09541 ( 979) 78 25.0 20 KIAA0557 ( 493 res) hh01334 ( 493) 75 23.9 22 KIAA0161 ( 326 res) ha02800 ( 326) 73 23.2 24 >>KIAA0496 ( 218 res) hg00144 (218 aa) initn: 1137 init1: 1137 opt: 1137 Z-score: 1126.9 bits: 216.0 E(): 1.4e-57 Smith-Waterman score: 1137; 100.000% identity (100.000% similar) in 159 aa overlap (1-159:1-159) 10 20 30 40 50 60 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVS 10 20 30 40 50 60 70 80 90 100 110 120 FLJ003 ELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 ELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPT 70 80 90 100 110 120 130 140 150 160 170 180 FLJ003 KTGSELMEILDGMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETP ::::::::::::::::::::::::::::::::::::::: KIAA04 KTGSELMEILDGMDQSHRKEMQLYNSIFSLLSFEKIGYTGEAPRRLLHATQVWVGGLAAR 130 140 150 160 170 180 190 200 210 220 230 240 FLJ003 RFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRI KIAA04 SLGAAGSGHWALTAPDSRALDKLPVDRWTPRSRRQAGD 190 200 210 >>KIAA0222 ( 1204 res) ha02586 (1204 aa) initn: 79 init1: 50 opt: 125 Z-score: 128.3 bits: 33.7 E(): 0.06 Smith-Waterman score: 125; 28.182% identity (60.000% similar) in 110 aa overlap (33-136:70-175) 10 20 30 40 50 FLJ003 SPFPSSQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRN-LA--VEKAV ..::: .: : .::. .. :. ..: . KIAA02 LRMDRNREAEMELRRGPSPTRAGRGHEVDGDKATCHTC-CICGKSFPFQSSLSQHMRKHT 40 50 60 70 80 90 60 70 80 90 100 110 FLJ003 SELPSECGFC-LRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEA--AC .: : .: .: : .. :. : . . . : . . : ..:. :. . :. :: KIAA02 GEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAG---EAPLGEMRASEGLDAC 100 110 120 130 140 150 120 130 140 150 160 170 FLJ003 AHPTKTGSELMEILDGMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLY : :::..: ..:.: .:. KIAA02 ASPTKSASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAV 160 170 180 190 200 210 >>KIAA1095 ( 1098 res) hk06736 (1098 aa) initn: 81 init1: 59 opt: 116 Z-score: 119.8 bits: 32.0 E(): 0.18 Smith-Waterman score: 116; 24.167% identity (55.000% similar) in 120 aa overlap (7-119:62-170) 10 20 30 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEEQAT .. : ::..:::: . .. .... KIAA10 TMGFELDRFDGDVDPDLKCALCHKVLEDPLTTPC--GHVFCAGCVLPWVV------QEGS 40 50 60 70 80 40 50 60 70 80 90 FLJ003 CPN-CRCEISKSLCCRNLAVEKAVSELPSECGF----CLRQFPRSLLERHQKEECQDRVT :: :: ..: . . : ... . .: .:.. : : . : .: :.:. . KIAA10 CPARCRGRLSAKELNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHL-ERCDFAPA 90 100 110 120 130 140 100 110 120 130 140 FLJ003 QCKYKRIGCPWHGPFHELTVH-EAAC-AHPTKTGSELMEILDGMDQSHRKEMQLYNSIFS .:.. :: ... .: . :: :.: KIAA10 RCRH--AGCGQVLLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRA 150 160 170 180 190 200 >>KIAA1588 ( 613 res) fj08823 (613 aa) initn: 52 init1: 52 opt: 112 Z-score: 117.8 bits: 30.8 E(): 0.23 Smith-Waterman score: 112; 24.528% identity (52.830% similar) in 106 aa overlap (4-107:295-396) 10 20 30 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEE :: ::: :. .. ::. .. :. KIAA15 EKPYECSDCGKAFNDPSALRSHARTHLKEKPFDCSQCGNAFRTLSALKIHM--RVHTGER 270 280 290 300 310 320 40 50 60 70 80 90 FLJ003 QATCPNCRCEISKSLCCRNLAVEKA-VSELPSECGFCLRQFPR-SLLERHQKEECQDRVT : .: ..: :. .: ... ..: : :: : . : . : :..: ... .. KIAA15 PYKCDQCGKAYGRS--CHLIAHKRTHTGERPYECHDCGKAFQHPSHLKEHVRNHTGEKPY 330 340 350 360 370 380 100 110 120 130 140 150 FLJ003 QCKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFSLL : . :.. :. KIAA15 ACTQCGKAFRWKSNFNLHKKNHMVEKTYECKECGKSFGDLVSRRKHMRIHIVKKPVECRQ 390 400 410 420 430 440 >>KIAA1015 ( 841 res) hk03609(revised) (841 aa) initn: 50 init1: 50 opt: 112 Z-score: 116.7 bits: 31.1 E(): 0.26 Smith-Waterman score: 112; 24.779% identity (49.558% similar) in 113 aa overlap (4-113:718-826) 10 20 30 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEE :. . : .. . . . : . . : KIAA10 QKNEKNGICEEAYSWNLTVIEDKKIELQEQPYQCDICGKAFGYSSDLIQHYRTHTAEKPY 690 700 710 720 730 740 40 50 60 70 80 90 FLJ003 QATCPNCRCEISKSLCCRNLAVEKAVSELPS-ECGFCLRQFP-RSLLERHQKEECQDRVT : : :: .... : .. .: : : .: : : : .: :..::. . .. KIAA10 Q--CDICRENVGQ--CSHTKQHQKIYSSTKSHQCHECGRGFTLKSHLNQHQRIHTGEKPF 750 760 770 780 790 800 100 110 120 130 140 150 FLJ003 QCKYKRIGCPWHGP-FHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFSL ::: .. : :..: :: KIAA10 QCKECGMNFSWSCSLFKHLRSHERTDPINTLSVEGSLL 810 820 830 840 >>KIAA1339 ( 409 res) fj00071 (409 aa) initn: 42 init1: 42 opt: 107 Z-score: 114.3 bits: 29.6 E(): 0.36 Smith-Waterman score: 109; 28.000% identity (51.000% similar) in 100 aa overlap (7-93:126-224) 10 20 30 FLJ003 ASSPFPSSQCTNG--H-LMCAGCFIHLLADARLK-- . ::... : : :: : :. .: :. KIAA13 LGSYPLPPPVGEQVFSCHHCGKNLSQDMLLTHQCSHATEHPLPCAQCPKHFTPQADLSST 100 110 120 130 140 150 40 50 60 70 80 FLJ003 ------EEQATCPNC-RCEISKSLCCRNLAVEKAVSELPSECGFCLRQFP-RSLLERHQK : :::.: : : .: :... .: : : : ..: .. : :.. KIAA13 SQDHASETPPTCPHCARTFTHPSRLTYHLRVHNS-TERPFPCPDCPKRFADQARLTSHRR 160 170 180 190 200 210 90 100 110 120 130 140 FLJ003 EECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQL . ..: .: KIAA13 AHASERPFRCAQCGRSFSLKISLLLHQRGHAQERPFSCPQCGIDFNGHSALIRHQMIHTG 220 230 240 250 260 270 >>KIAA0426 ( 613 res) hh01274 (613 aa) initn: 44 init1: 44 opt: 108 Z-score: 113.9 bits: 30.1 E(): 0.38 Smith-Waterman score: 108; 27.174% identity (55.435% similar) in 92 aa overlap (5-94:367-454) 10 20 30 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEEQ . ..: .. . :: : :. .: : : KIAA04 KPYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQ 340 350 360 370 380 390 40 50 60 70 80 90 FLJ003 ATCPNCRCEISK-SLCCRNLAVEKAVSELPSECGFCLRQFPR-SLLERHQKEECQDRVTQ : .: .:. :. .. .:. ... : ::. : . : : : ::. . ... : KIAA04 --CTQCNKSFSRRSILTQHQGVHTGAK--PYECNECGKAFVYNSSLVSHQEIHHKEKCYQ 400 410 420 430 440 450 100 110 120 130 140 150 FLJ003 CKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFSLLS :: KIAA04 CKECGKSFSQSGLIQHQRIHTGEKPYKCDVCEKAFIQRTSLTEHQRIHTGERPYKCDKCG 460 470 480 490 500 510 >>KIAA1508 ( 573 res) hk06576 (573 aa) initn: 42 init1: 42 opt: 106 Z-score: 112.1 bits: 29.7 E(): 0.48 Smith-Waterman score: 130; 29.787% identity (56.383% similar) in 94 aa overlap (4-93:408-495) 10 20 30 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEE :. :.: . . .: : : : .. : KIAA15 ERPYVCSECGKSFGQKSVLIQHQRVHTGERPYECSECGKVFSQSSGLFRHRRAHTKTKPY 380 390 400 410 420 430 40 50 60 70 80 FLJ003 QATCPNCRCEISKSLCCR-NLAVEKAV--SELPSECGFCLRQFPRSL-LERHQKEECQDR . : .:. ::. :. .: ...: .: : ::. : ..: :. : ::: . ..: KIAA15 E--CSECE----KSFSCKTDLIRHQTVHTGERPYECSVCGKSFIRKTHLIRHQTVHTNER 440 450 460 470 480 490 90 100 110 120 130 140 FLJ003 VTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFS .: KIAA15 PYECDECGKSYSQSSALLQHRRVHTGERPYECRECGKSFTRKNHLIQHKTVHTGERPYEC 500 510 520 530 540 550 >>KIAA1285 ( 785 res) hh11563(revised) (785 aa) initn: 66 init1: 44 opt: 106 Z-score: 111.1 bits: 29.9 E(): 0.55 Smith-Waterman score: 106; 27.368% identity (52.632% similar) in 95 aa overlap (4-93:660-749) 10 20 30 FLJ003 ASSPFPSSQCTNGHLMCAGCFIHLLADARLKEE :. .: .. .. : . .. :. KIAA12 PERGPTFNPKHALKPRPKSPSSGSGGGGPKPYKCPECDSSFSHKSSLTKHQI--THTGER 630 640 650 660 670 680 40 50 60 70 80 FLJ003 QATCPNC----RCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPR-SLLERHQKEECQD :::.: : .:: . : : .. :: . :..: ..: : : : :::. . . KIAA12 PYTCPECKKSFRLHISLVIHQRVHAGKHEVSFI---CSLCGKSFSRPSHLLRHQRTHTGE 690 700 710 720 730 740 90 100 110 120 130 140 FLJ003 RVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIF : .: KIAA12 RPFKCPECEKSFSEKSKLTNHCRVHSRERPPPRWSSSFCSL 750 760 770 780 >>KIAA0326 ( 927 res) hg00579 (927 aa) initn: 88 init1: 63 opt: 106 Z-score: 110.5 bits: 30.1 E(): 0.59 Smith-Waterman score: 106; 24.413% identity (50.704% similar) in 213 aa overlap (17-211:269-470) 10 20 30 40 FLJ003 ASSPFPSSQCTNGHLMCAGCFI---HLLADARLK--EEQATCPNCR :. :: .:. : . :. : .:. KIAA03 SECGKSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECE 240 250 260 270 280 290 50 60 70 80 90 FLJ003 CEISKSLCCRNLAVEKA--VSELPSECGFCLRQFPRSL-LERHQKEECQDRVTQCKY--K ...: :: .. ..: : .:: : : : :: : .:: . .. .: : KIAA03 KAFTQST---NLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGK 300 310 320 330 340 350 100 110 120 130 140 150 FLJ003 RIGCPWHGPFHELTVHEAACAHP-TKTGSELMEI--LDGMDQSHRKEMQLYNSIFSLLSF :.: :. ... .: . . :. :. ... : ...: : . :. . :: KIAA03 RFG-QNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGE-KPYECLECGKSF 360 370 380 390 400 410 160 170 180 190 200 FLJ003 EKIGYTEVQFRPYRT----DDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLS-CKR :.. . .. :: : : . .: :: :. : . . :.. .:: . : . KIAA03 ---GHSSTLIKHQRTHLREDPFKCPVCGKT--FT-LSATLLRHQRTHTGERPYKCPECGK 420 430 440 450 460 210 220 230 240 250 260 FLJ003 TLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVE ..: KIAA03 SFSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIR 470 480 490 500 510 520 289 residues in 1 query sequences 2210705 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 11:01:40 2009 done: Fri Feb 27 11:01:41 2009 Total Scan time: 0.440 Total Display time: 0.040 Function used was FASTA [version 34.26.5 April 26, 2007]