# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh01540.fasta.huge -Q ../query/FLJ00277.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00277, 357 aa vs ./tmplib.10216 library 2210637 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 8.6853+/-0.00759; mu= -1.6853+/- 0.509 mean_var=358.5674+/-80.567, 0's: 0 Z-trim: 0 B-trim: 0 in 0/40 Lambda= 0.067731 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1810 ( 579 res) fk03376 ( 579) 149 27.8 2.2 KIAA1818 ( 1157 res) hg00622 (1157) 155 28.8 2.2 KIAA1096 ( 1919 res) pf00402 (1919) 155 29.1 2.9 KIAA0669 ( 825 res) hk02346 ( 825) 140 27.1 4.9 KIAA1071 ( 675 res) hj05664s2 ( 675) 138 26.8 5 KIAA0079 ( 1102 res) ha03543 (1102) 140 27.3 5.8 KIAA1020 ( 638 res) fg00473s1 ( 638) 132 26.2 7.2 KIAA0269 ( 567 res) ha06751 ( 567) 129 25.8 8.2 FLJ00353 ( 1766 res) sh01144 (1766) 136 27.2 10 FLJ00198 ( 677 res) sj03504 ( 677) 127 25.8 10 KIAA1887 ( 967 res) fk02232 ( 967) 130 26.3 11 KIAA0574 ( 405 res) hj00204 ( 405) 119 24.7 13 KIAA1522 ( 1044 res) fh14706(revised) (1044) 127 26.0 13 KIAA0921 ( 1658 res) ah00573 (1658) 131 26.7 14 KIAA0495 ( 209 res) hg00106 ( 209) 113 23.7 14 KIAA0616 ( 634 res) hg03623 ( 634) 122 25.2 14 KIAA1814 ( 1285 res) ph00952 (1285) 128 26.2 14 FLJ00221 ( 298 res) sj06160 ( 298) 114 24.0 16 KIAA2032 ( 952 res) eh00720 ( 952) 123 25.6 17 KIAA1555 ( 2414 res) fh17482s2 (2414) 129 26.7 19 KIAA1306 ( 1154 res) fh05845 (1154) 122 25.6 20 KIAA0689 ( 547 res) hk03417 ( 547) 115 24.5 21 KIAA1760 ( 2219 res) af00030 (2219) 127 26.5 21 KIAA1086 ( 902 res) hj08218 ( 902) 119 25.1 21 KIAA1025 ( 1917 res) fg00971s1 (1917) 125 26.2 22 KIAA0284 ( 1573 res) pf09542 (1573) 122 25.8 24 KIAA0450 ( 1182 res) hj05822 (1182) 119 25.3 25 KIAA0429 ( 666 res) hk07754 ( 666) 114 24.5 25 KIAA1298 ( 738 res) fg04206 ( 738) 114 24.5 26 KIAA0023 ( 2111 res) ha00512 (2111) 122 25.9 28 KIAA0314 ( 1899 res) af02425 (1899) 121 25.8 29 KIAA0522 ( 1555 res) hg01393 (1555) 119 25.5 29 KIAA1741 ( 1777 res) fh23254 (1777) 120 25.6 29 KIAA1802 ( 821 res) fj21631 ( 821) 113 24.5 30 FLJ00090 ( 770 res) as00090 ( 770) 112 24.4 31 KIAA1138 ( 1239 res) hj05928 (1239) 116 25.0 31 KIAA1650 ( 797 res) hk02174 ( 797) 112 24.4 32 FLJ00139 ( 585 res) sh03241 ( 585) 109 23.9 32 KIAA0596 ( 1531 res) hg01605 (1531) 117 25.3 33 KIAA1375 ( 546 res) fj04426 ( 546) 108 23.8 33 KIAA0774 ( 1381 res) bh00283 (1381) 116 25.1 33 KIAA1608 ( 872 res) fj20142 ( 872) 112 24.4 33 KIAA1587 ( 991 res) fj08327 ( 991) 113 24.6 34 KIAA1994 ( 1117 res) bh00052 (1117) 114 24.8 34 FLJ00224 ( 896 res) sj06244 ( 896) 112 24.5 34 KIAA1509 ( 1365 res) fh14721 (1365) 115 25.0 35 KIAA0907 ( 569 res) hk10396 ( 569) 107 23.7 36 FLJ00091 ( 170 res) as00091 ( 170) 96 21.9 38 KIAA1311 ( 889 res) fh11512 ( 889) 110 24.3 39 FLJ00084 ( 641 res) as00084 ( 641) 107 23.8 39 >>KIAA1810 ( 579 res) fk03376 (579 aa) initn: 84 init1: 84 opt: 149 Z-score: 100.4 bits: 27.8 E(): 2.2 Smith-Waterman score: 149; 31.707% identity (46.341% similar) in 123 aa overlap (203-323:314-435) 180 190 200 210 220 230 FLJ002 LFIQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPDDMNNNSGA-PATAPD :.:: .: : ::. : .: : : KIAA18 QRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPG 290 300 310 320 330 340 240 250 260 270 280 290 FLJ002 SAGQPPALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAAGGDLGWMAETAAIITDASFL : .:: : . :.:: : :: . ..:: . . ::: : .. KIAA18 MFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSGAATTTAAGTSATAASATASGPG 350 360 370 380 390 400 300 310 320 330 340 350 FLJ002 SGLSASLLERRPASPLGPAG-GLPHAPQDSVPPSDSAASDTTPLGAAVGGPSPASMAPTE :: :: :. :. : :.: : . :: KIAA18 SG-SAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHL 410 420 430 440 450 460 FLJ002 APSEVGS KIAA18 EARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIP 470 480 490 500 510 520 >>KIAA1818 ( 1157 res) hg00622 (1157 aa) initn: 83 init1: 83 opt: 155 Z-score: 100.4 bits: 28.8 E(): 2.2 Smith-Waterman score: 155; 28.571% identity (55.495% similar) in 182 aa overlap (189-357:535-705) 160 170 180 190 200 210 FLJ002 FNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPDD ::. : : : :: : ::. KIAA18 PLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQP---QPPPPPQQPPPPLPQP 510 520 530 540 550 560 220 230 240 250 260 270 FLJ002 MNNNS----GAPATAPDSAGQPPALG-PVSPGASGSPGPVAAAPSSLVAAAASVAAAAGG . .: : ::. :. :: . ::. :...:. .... :. : :.. ....: KIAA18 QAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPA-ITTGGSAAVLAGTIKTSVTGT 570 580 590 600 610 620 280 290 300 310 320 330 FLJ002 DLGWMAETAAIITDASFLSGLSASLLE---RRPASPLGPAGGLPHAPQDSVPPSDSAASD .. : .. .:... ..:. :. .. .: :::..: :.: .: :.: . . KIAA18 SMPTGAVSGNVIVNT--IAGVPAATFQSINKRLASPVAP-GALT-TPGGSAP---AQVVH 630 640 650 660 670 340 350 FLJ002 TTPLGAAVGGPSPA-----SMAPTEAPSEVGS : : :::.:. : ::: :.. : : KIAA18 TQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQA 680 690 700 710 720 730 KIAA18 TGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQ 740 750 760 770 780 790 >>KIAA1096 ( 1919 res) pf00402 (1919 aa) initn: 135 init1: 88 opt: 155 Z-score: 98.1 bits: 29.1 E(): 2.9 Smith-Waterman score: 170; 26.946% identity (59.880% similar) in 167 aa overlap (193-354:803-958) 170 180 190 200 210 FLJ002 YSSLALVTSWLFIQHSMIYFFHHYELPAILQQVRIQEMLLQA--PPLG--PGTPTALPDD : . ::. .: :::. : :..: KIAA10 EQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTLAP- 780 790 800 810 820 830 220 230 240 250 260 270 FLJ002 MNNNSGAPATAPDSAGQPPALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAAGGDLGWM .. .... :..: :.. . .:... .: :. :. :.. :::. :.... . KIAA10 VSASASVSASVPASTSAAAITSSSAPASAPAPTPILAS----VSTPASVTILASASIPIL 840 850 860 870 880 280 290 300 310 320 330 FLJ002 AETAAIITDASFLSGLSASLLERRPASPLGPAGGLP-HAPQDSVPPSDSAASDTTPLGAA : .:. . .. . .:: ::.:. : .: :: ::: . ..:: .: . KIAA10 A--SALASTSAPTPAPAAS----SPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTP 890 900 910 920 930 940 340 350 FLJ002 VGGPSPASMAPTEAPSEVGS :..:.:: ::... .. KIAA10 VSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSI 950 960 970 980 990 1000 >>KIAA0669 ( 825 res) hk02346 (825 aa) initn: 185 init1: 120 opt: 140 Z-score: 94.0 bits: 27.1 E(): 4.9 Smith-Waterman score: 140; 25.373% identity (55.224% similar) in 134 aa overlap (203-332:490-623) 180 190 200 210 220 230 FLJ002 LFIQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPDDMNNNSGAPATAPDS :. ..: ::..: .. : .: . KIAA06 TGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAG 460 470 480 490 500 510 240 250 260 270 280 290 FLJ002 AGQPPALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAAGG-DLGWMAETAAIITDASFL :::: .. : . :.:: . : ..: ..: .. .: ::. . .. .. :.. . .. KIAA06 AGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAP 520 530 540 550 560 570 300 310 320 330 340 FLJ002 SGLSASLLERRP---ASPLGPAGGLPHAPQDSVPPSDSAASDTTPLGAAVGGPSPASMAP . : .: . : .: . ::: :: :.. :: . KIAA06 LAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDT 580 590 600 610 620 630 350 FLJ002 TEAPSEVGS KIAA06 RRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPVDGDEDRN 640 650 660 670 680 690 >>KIAA1071 ( 675 res) hj05664s2 (675 aa) initn: 209 init1: 101 opt: 138 Z-score: 93.9 bits: 26.8 E(): 5 Smith-Waterman score: 161; 27.333% identity (62.000% similar) in 150 aa overlap (212-355:471-618) 190 200 210 220 230 FLJ002 FFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPDDMNNNSGAPATAPDSAGQPPAL-- : ..: . . : : . .: .. KIAA10 LLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVA 450 460 470 480 490 500 240 250 260 270 280 290 FLJ002 -GPVSPGASGSPGPVAA-APSSLVAAAASVAAAAGGDLGWMAETAAIITDASFLSGLSAS .::. .:...:. .:: .:.. .:.::.:. ::.:.. : .:. . : :. .:. KIAA10 AAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP--SAAAAA 510 520 530 540 550 300 310 320 330 340 350 FLJ002 LLERRPASPLG-PAGGLPHAPQDSVPPSDSAASDTTPLGAAVGGPSPA-SMAPTEAPSEV .. ::.: :: .: .: .. ... :. .: .: . .:.:: . .:. : .:: KIAA10 AVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEV 560 570 580 590 600 610 FLJ002 GS KIAA10 PASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMVEYLI 620 630 640 650 660 670 >>KIAA0079 ( 1102 res) ha03543 (1102 aa) initn: 153 init1: 73 opt: 140 Z-score: 92.7 bits: 27.3 E(): 5.8 Smith-Waterman score: 153; 34.328% identity (57.463% similar) in 134 aa overlap (224-354:119-242) 200 210 220 230 240 250 FLJ002 QVRIQEMLLQAPPLGPGTPTALPDDMNNNSGAPATAPDSAGQPPALGPVSPGASGSPGPV :.: :: ..:::.: : .: ... : KIAA00 AAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSP-LAP-VGNQPPVLQPYGPPPTSA--QV 90 100 110 120 130 140 260 270 280 290 300 310 FLJ002 AAAPSSLVAAAASVAAAAGGDLGWMAETAAIITDASFL-SGLSASLLERRPASPLGPAGG :. :.. ..: . : .. ::. :. ...:: ::: .: . : ::. : : KIAA00 ATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGLYGSY-PQGQAPPLSQAQG 150 160 170 180 190 200 320 330 340 350 FLJ002 LP--HAPQDSVPPSDSAASDTTPLGAAVGGPSPASMAPTEAPSEVGS : ..:: :.: : ::. :: : ::: ::. :.. KIAA00 HPGIQTPQRSAP---SQASSFTP--PASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSP 210 220 230 240 250 KIAA00 PQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQP 260 270 280 290 300 310 >>KIAA1020 ( 638 res) fg00473s1 (638 aa) initn: 114 init1: 77 opt: 132 Z-score: 91.0 bits: 26.2 E(): 7.2 Smith-Waterman score: 132; 28.571% identity (47.619% similar) in 147 aa overlap (203-343:275-417) 180 190 200 210 220 230 FLJ002 LFIQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTA--LPDDMNNNSGAPATAP ..::: :.:: ::: . : . .: KIAA10 GGEAGLGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSP 250 260 270 280 290 300 240 250 260 270 280 FLJ002 DSAGQPPALGPVSPGASGSP-GPVAAAPSSLVAAAA---SVAAAAGGDLGWMAETAAIIT .:. :: :. .:: : : . : .: .: :. : ::. . .. KIAA10 PAASAPP----VANSASYSELGGTPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKK 310 320 330 340 350 360 290 300 310 320 330 340 FLJ002 DASFLSGLSASLLERRPASPLGPAGGLPHAPQDSVPPSDSAASDTTPLGAAVGGPSPASM . . ...: .::: :.: :: : . :. :: . : : : : KIAA10 EWGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKE 370 380 390 400 410 420 350 FLJ002 APTEAPSEVGS KIAA10 EEENGKDASEDSAQSGSEGGSGHASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQL 430 440 450 460 470 480 >>KIAA0269 ( 567 res) ha06751 (567 aa) initn: 116 init1: 64 opt: 129 Z-score: 89.9 bits: 25.8 E(): 8.2 Smith-Waterman score: 143; 28.571% identity (45.238% similar) in 168 aa overlap (188-355:339-486) 160 170 180 190 200 210 FLJ002 RFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPD ::. :. .. . ..:: : .: : KIAA02 TGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPP--PPVPPP-PP 310 320 330 340 350 360 220 230 240 250 260 270 FLJ002 DMNNNSGAPATAPDSAGQPPALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAAGGDLGW . :::. : ::: ..::. :.: :: :: . :: :: KIAA02 PPATALQAPAVPP-----PPAPLQIAPGVL-HPAPPPIAPP-LVQPSPPVARAAP----- 370 380 390 400 410 280 290 300 310 320 330 FLJ002 MAETAAIITDASFLSGLSASLLERRPASPLGPAGGLPHAPQDSVPPSDSAASDTTPLGAA . ::. . . .: .: : :: : : : .: .: : : .. KIAA02 VCETVPV---HPLPQGEVQGLPPPPPPPPLPPPGIRPSSPV-TVTALAHPPSGLHPTPST 420 430 440 450 460 340 350 FLJ002 VGGPSPASMAPTEAPSEVGS . :: : :. ::.: KIAA02 APGPHVPLMPPSP-PSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQ 470 480 490 500 510 520 >>FLJ00353 ( 1766 res) sh01144 (1766 aa) initn: 100 init1: 72 opt: 136 Z-score: 88.4 bits: 27.2 E(): 10 Smith-Waterman score: 141; 30.769% identity (53.846% similar) in 143 aa overlap (205-334:192-330) 180 190 200 210 220 230 FLJ002 IQHSMIYFFHHYELPAILQQVRIQEMLLQAPPLGPGT--PTALPDDMNNNSGAPATAP-- :: : . : ..: .... . :. : FLJ003 PVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPS 170 180 190 200 210 220 240 250 260 270 280 FLJ002 -DSAGQPPALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAAGGDLGWMAE-TAAIITDA .::: ::.: : : .: .: :: : :. : : . ::: . : FLJ003 LSSAGPPPVLPPPSL-SSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPA 230 240 250 260 270 280 290 300 310 320 330 340 FLJ002 SFLSGLSASLLER-RPA---SPLGPAGGLP---HAPQDSVPPSDSAASDTTPLGAAVGGP : :. :... :. ::: .:.. ... : : : .:. ::... : . :: FLJ003 S--SSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKA-PLSKSALPY 290 300 310 320 330 350 FLJ002 SPASMAPTEAPSEVGS FLJ003 SSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDL 340 350 360 370 380 390 >>FLJ00198 ( 677 res) sj03504 (677 aa) initn: 147 init1: 65 opt: 127 Z-score: 88.1 bits: 25.8 E(): 10 Smith-Waterman score: 127; 30.282% identity (52.113% similar) in 142 aa overlap (209-342:540-674) 180 190 200 210 220 230 FLJ002 MIYFFHHYELPAILQQVRIQEMLLQAPPLGPGTPTALPDDMNNNSGAPATAPDSAG--QP :: .. : . :: :. : .:: :: FLJ001 PRHLAIANPHFWAECDAGGREGSFAGAAAAPGGAAGEP--AGPCPGAAAAEPAGAGAQQP 510 520 530 540 550 560 240 250 260 270 280 290 FLJ002 PALGPVSPGASGSPGPVAAAPSSLVAAAASVAAAA--GGD----LGWMAETAAIITDASF :: : : :: :: ::: . :........: ::: : . . : :. FLJ001 PAGREVCAGDSG-PG---AAPEAGGAGGGGAGGTAVPGGDPRAAAGPASGPQGPGTAAAA 570 580 590 600 610 620 300 310 320 330 340 350 FLJ002 LSGLSASLLERRPASPLGPAGGLPHAPQDSVPPSDSAASDTTPLGAAVGGPSPASMAPTE .: . . : : : .: .: .. :. .::. . :.. :::. FLJ001 AGGRARGTAGAAP-RPQGQHAGTGAGPPGAAGPARAAAGPAGQRGGTGGGPAGRA 630 640 650 660 670 FLJ002 APSEVGS 357 residues in 1 query sequences 2210637 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:50:47 2009 done: Fri Feb 27 10:50:47 2009 Total Scan time: 0.480 Total Display time: 0.080 Function used was FASTA [version 34.26.5 April 26, 2007]