# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh03991.fasta.huge -Q ../query/FLJ00359.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00359, 1056 aa vs ./tmplib.10216 library 2209938 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 4.6734+/-0.00416; mu= 19.6846+/- 0.281 mean_var=102.0456+/-22.443, 0's: 0 Z-trim: 9 B-trim: 0 in 0/40 Lambda= 0.126963 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 39, opt: 27, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) FLJ00206 ( 702 res) sj04644 ( 702) 3092 577.5 2.6e-165 FLJ00255 ( 733 res) sj09579 ( 733) 3020 564.3 2.5e-161 KIAA0926 ( 1447 res) hh02962 (1447) 231 53.9 2.3e-07 FLJ00180 ( 499 res) sj01466 ( 499) 152 38.8 0.0028 FLJ00398 ( 660 res) sj06617 ( 660) 134 35.6 0.032 FLJ00348 ( 778 res) sg00015 ( 778) 134 35.7 0.036 FLJ00240 ( 383 res) sj07454 ( 383) 119 32.6 0.16 KIAA1234 ( 727 res) fh08618 ( 727) 120 33.1 0.2 KIAA1835 ( 623 res) fh08795s1 ( 623) 119 32.8 0.21 KIAA0980 ( 1406 res) hj07083 (1406) 115 32.6 0.56 FLJ00330 ( 246 res) sj03258 ( 246) 104 29.6 0.81 FLJ00276 ( 426 res) sh00612 ( 426) 103 29.7 1.3 KIAA0159 ( 1406 res) ha03574 (1406) 106 30.9 1.8 KIAA1185 ( 403 res) hg02311a ( 403) 99 28.9 2.1 KIAA0881 ( 1064 res) hk07534 (1064) 99 29.5 3.7 KIAA1804 ( 490 res) fj22769 ( 490) 94 28.1 4.3 FLJ00036 ( 706 res) as00036 ( 706) 94 28.3 5.4 FLJ00104 ( 287 res) as00104 ( 287) 88 26.7 6.8 KIAA1307 ( 1678 res) fh08302 (1678) 96 29.2 7 KIAA1125 ( 1205 res) hk07594 (1205) 94 28.7 7.4 KIAA1694 ( 757 res) fj11293 ( 757) 90 27.6 9.4 KIAA0156 ( 963 res) ha03253 ( 963) 91 28.0 9.5 KIAA0315 ( 1841 res) hg00246 (1841) 94 28.9 9.5 KIAA0795 ( 465 res) hk06104 ( 465) 87 26.8 10 KIAA1149 ( 532 res) fg04087 ( 532) 86 26.7 13 KIAA0189 ( 1132 res) ha02928 (1132) 89 27.7 13 FLJ00028 ( 91 res) as00028 ( 91) 77 24.0 14 KIAA0118 ( 161 res) ha00793 ( 161) 79 24.7 15 KIAA0631 ( 729 res) hh01881s1 ( 729) 86 26.9 15 KIAA1575 ( 1010 res) fj01374s1 (1010) 87 27.3 16 KIAA1590 ( 1393 res) fj09048y1 (1393) 88 27.6 17 KIAA0211 ( 1317 res) ha02768 (1317) 87 27.4 19 KIAA0963 ( 1391 res) hj05936 (1391) 87 27.5 20 KIAA1768 ( 1207 res) ph00672(revised) (1207) 86 27.2 20 KIAA0998 ( 1226 res) hk08691 (1226) 86 27.2 21 KIAA0142 ( 802 res) ha01169 ( 802) 84 26.6 21 KIAA1793 ( 1270 res) fj07087 (1270) 86 27.2 21 KIAA0304 ( 2415 res) af07172 (2415) 89 28.1 21 KIAA1163 ( 437 res) hj05329 ( 437) 81 25.7 21 KIAA1799 ( 610 res) fj20761 ( 610) 82 26.1 23 KIAA0840 ( 523 res) hk04921s1 ( 523) 81 25.8 24 KIAA1106 ( 1154 res) fg01888 (1154) 84 26.8 26 KIAA0014 ( 513 res) ha00442 ( 513) 80 25.6 26 KIAA1244 ( 1872 res) hf00438s1 (1872) 86 27.4 26 FLJ00392 ( 274 res) sj05126 ( 274) 77 24.7 27 KIAA1398 ( 1586 res) ha02572 (1586) 85 27.2 27 KIAA1236 ( 1840 res) pg00641 (1840) 85 27.3 30 FLJ00101 ( 294 res) as00101 ( 294) 76 24.5 31 FLJ00324 ( 376 res) sj01157 ( 376) 77 24.9 32 KIAA0815 ( 1640 res) sh06087 (1640) 83 26.8 36 >>FLJ00206 ( 702 res) sj04644 (702 aa) initn: 3083 init1: 3083 opt: 3092 Z-score: 3061.0 bits: 577.5 E(): 2.6e-165 Smith-Waterman score: 3092; 97.669% identity (98.517% similar) in 472 aa overlap (577-1048:1-471) 550 560 570 580 590 600 FLJ003 TTAELQRAPDLQESDGQRKGAQSRSLTLRLQKCQLQVHDAEALIALLQEGPHLEEVDLSG :::::::::::::::::::::::::::::: FLJ002 QKCQLQVHDAEALIALLQEGPHLEEVDLSG 10 20 30 610 620 630 640 650 660 FLJ003 NQLEDEGCRLMAEAASQLHIARKLDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 NQLEDEGCRLMAEAASQLHIARKLDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKT 40 50 60 70 80 90 670 680 690 700 710 720 FLJ003 VIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKHLEQLCKALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 VIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKHLEQLCKALG 100 110 120 130 140 150 730 740 750 760 770 780 FLJ003 GSCHLGHLHLDFSGNALGDEGAARLAQLLPGLGALQSLNLSENGLSLDAVLGLVRCFSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 GSCHLGHLHLDFSGNALGDEGAARLAQLLPGLGALQSLNLSENGLSLDAVLGLVRCFSTL 160 170 180 190 200 210 790 800 810 820 830 840 FLJ003 QWLFRLDISFESQHILLRGDKTSRDMWATGSLPDFPAAAKFLGFRQRCIPRSLCLSECPL :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: FLJ002 QWLFRLDISFESQHILLRGDKTSRDMWATGSLPDFPAAAKFLGFRKRCIPRSLCLSECPL 220 230 240 250 260 270 850 860 870 880 890 900 FLJ003 EPPSLTRLCATLKDCPGPLELQLSCEFLSDQSLETLLDCLPQLPQLSLLQLSQTGLSPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 EPPSLTRLCATLKDCPGPLELQLSCEFLSDQSLETLLDCLPQLPQLSLLQLSQTGLSPKS 280 290 300 310 320 330 910 920 930 940 950 960 FLJ003 PFLLANTLSLCPRVKKVDLRSLHHATLHFRSNEEEEGVCCGRFTGCSLSQEHVESLCWLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 PFLLANTLSLCPRVKKVDLRSLHHATLHFRSNEEEEGVCCGRFTGCSLSQEHVESLCWLL 340 350 360 370 380 390 970 980 990 1000 1010 1020 FLJ003 SKCKDLSQVDLSANLLGDSGLRCLLECLPQVPISGLLDLSHNSISQESALYLLETLPSCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 SKCKDLSQVDLSANLLGDSGLRCLLECLPQVPISGLLDLSHNSISQESALYLLETLPSCP 400 410 420 430 440 450 1030 1040 1050 FLJ003 RVREASVKCLGSWHVWAPCFPRPFSLQPGL :::::::. ::: . . : : FLJ002 RVREASVN-LGSEQSFRIHFSREDQAGKTLRLSECSFRPEHVSRLATGLSKSLQLTELTL 460 470 480 490 500 >>FLJ00255 ( 733 res) sj09579 (733 aa) initn: 3020 init1: 3020 opt: 3020 Z-score: 2989.6 bits: 564.3 E(): 2.5e-161 Smith-Waterman score: 3020; 99.553% identity (99.553% similar) in 447 aa overlap (1-447:287-733) 10 20 30 FLJ003 SELLFDLYLSPESDHDTVFQYLEKNADQVL :::::::::::::::::::::::::::::: FLJ002 KWAEGHLNCFQALFLFEFRQLNLITRFLTPSELLFDLYLSPESDHDTVFQYLEKNADQVL 260 270 280 290 300 310 40 50 60 70 80 90 FLJ003 LIFDGLDEALQPMGPDGPGPVLTLFSHLCNGTLLPGCRVMATSRPGKLPACLPAEAAMVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 LIFDGLDEALQPMGPDGPGPVLTLFSHLCNGTLLPGCRVMATSRPGKLPACLPAEAAMVH 320 330 340 350 360 370 100 110 120 130 140 150 FLJ003 MLGFDGPRVEEYVNHFFSAQPSREGALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 MLGFDGPRVEEYVNHFFSAQPSREGALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDH 380 390 400 410 420 430 160 170 180 190 200 210 FLJ003 APGQSVALLPNMTQLYMQMVLALSPPGHLLTSSLLDLGEVALRGLETGKVIFYAKDIAPP ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::: FLJ002 APGQSVALLPNMTQLYMQMVLALSPPGHLPTSSLLDLGEVALRGLETGKVIFYAKDIAPP 440 450 460 470 480 490 220 230 240 250 260 270 FLJ003 LIAFGATHSLLTSFCVRTGPGHQQTGYAFTHLSLQEFLAALHLMASPKVNKDTLTQYVTL :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: FLJ002 LIAFGATHSLLTSFCVCTGPGHQQTGYAFTHLSLQEFLAALHLMASPKVNKDTLTQYVTL 500 510 520 530 540 550 280 290 300 310 320 330 FLJ003 HSRWVQRTKARLGLSDHLPTFLAGLASCTCRPFLSHLAQGNEDCVGAKQAAVVQVLKKLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 HSRWVQRTKARLGLSDHLPTFLAGLASCTCRPFLSHLAQGNEDCVGAKQAAVVQVLKKLA 560 570 580 590 600 610 340 350 360 370 380 390 FLJ003 TRKLTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFPLTCTDLATLTNILEHREA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 TRKLTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFPLTCTDLATLTNILEHREA 620 630 640 650 660 670 400 410 420 430 440 450 FLJ003 PIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLGLAG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ002 PIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLG 680 690 700 710 720 730 460 470 480 490 500 510 FLJ003 SKITARGISHLVKALPLCPQLKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSIC >>KIAA0926 ( 1447 res) hh02962 (1447 aa) initn: 300 init1: 104 opt: 231 Z-score: 225.5 bits: 53.9 E(): 2.3e-07 Smith-Waterman score: 303; 23.721% identity (48.837% similar) in 645 aa overlap (18-630:413-971) 10 20 30 40 FLJ003 SELLFDLYLSPESDHDTVFQYLEKNADQVLLIFDGLDE---ALQPMG . : : . ...:.:.::.:: .:: . KIAA09 FYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSR-PERLLFILDGVDEPGWVLQEPS 390 400 410 420 430 440 50 60 70 80 90 FLJ003 PD------GPGPVLTLFSHLCNGTLLPGCRVMATSRPGKLPACLPA--EAAMVHMLGFDG . : :. .:.. : . :.:: . :.: : .:. .: :..:::. KIAA09 SELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSE 450 460 470 480 490 500 100 110 120 130 140 150 FLJ003 PRVEEYVNHFFSAQPSREGALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDHAPGQSV .:: ..:. . . :. ...: .: .:: :: . .:: :: . . . ... KIAA09 SSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRK---EKL 510 520 530 540 550 160 170 180 190 200 210 FLJ003 ALLPNMTQLYMQMVLALSPPGHLLTSSLLDLGEVALRGLETGKVIFYAKDIAPPLIAFGA .: . : :: . .. : .: :: .: .:. :..: : : : KIAA09 TLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDD----LRKHGL 560 570 580 590 600 610 220 230 240 250 260 270 FLJ003 THSLLTSFCVRTGPGHQQT---GYAFTHLSLQEFLAALHLMASPKVNKDTLTQYVTLHSR .....: .. : ... .:.: :: .:::.::. . . .. .. . . KIAA09 DGAIISTF-LKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEK 620 630 640 650 660 670 280 290 300 310 320 330 FLJ003 WVQRTKARLGLSDHLPTFLAGLASCTCRPFLSHLAQGNEDCVGAKQAAVVQVLKKLATRK .. . .. :: :: : . . .. . : .. ..: . .: . KIAA09 TLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFH----CRLSQGRNLMQWVPSL--QL 680 690 700 710 720 340 350 360 370 380 390 FLJ003 LTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFPLTCTDLATLTNILEHREAPIH : :. .: ::. ::.. . ::... : : KIAA09 LLQPHSLESLHCLYETRNKTF--------------------------LTQVMAHFE---- 730 740 750 400 410 420 430 440 450 FLJ003 LDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLGLAGSKI .. : .: : :: : .: .:: . .::.. KIAA09 -EMGMC-VETDM-ELLV-C---------------TFCIKFSRHVK---KLQLI------- 760 770 780 460 470 480 490 500 510 FLJ003 TARGISHLVKALPLCPQLKEVSFRDNQLSD---QVVLNIVEVLPHLPRLRKLDLSSNSIC .: .: : : :: ..: :.......: .: ..::::.::. KIAA09 --EGRQHRSTWSPTMVVL----FRWVPVTDAYWQILFSVLKVTRNL---KELDLSGNSLS 790 800 810 820 830 520 530 540 550 560 FLJ003 VSTL--LC--LARVAVTCPTVRM----LQAREA-DLIFLLSPPTETTAELQRAPDLQESD :.. :: : : :.:. : :.. :: : : ..: .::. . .. . KIAA09 HSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRA-NQTLTELDLSFNVLTDA 840 850 860 870 880 890 570 580 590 600 610 FLJ003 GQRKGAQS-RSLTLRLQK-----CQLQVHDAEALIALLQEGPHLEEVDLSGNQLEDEGCR : .. : :. . .::. : : . : ..:. .: :.:.::. :.:.: : : KIAA09 GAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVR 900 910 920 930 940 950 620 630 640 650 660 670 FLJ003 LMAEAASQLHIARKLDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQEP :. :. : : :: KIAA09 LLCEGLR--HPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGL 960 970 980 990 1000 1010 >>FLJ00180 ( 499 res) sj01466 (499 aa) initn: 411 init1: 136 opt: 152 Z-score: 152.2 bits: 38.8 E(): 0.0028 Smith-Waterman score: 267; 24.597% identity (53.831% similar) in 496 aa overlap (344-810:3-482) 320 330 340 350 360 370 FLJ003 CVGAKQAAVVQVLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPY-QLPFHNFP ::. : :. ::: . ... : . : FLJ001 VLHCLHELQHTELARSVEEAMESGALARLTGP 10 20 30 380 390 400 410 420 430 FLJ003 LTCTDLATLTNILEH--REAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFA . :: : .. . .:: . :... :. :. :. : ..: . . . : FLJ001 AHRAALAYLLQVSDACAQEANLSLSLSQGVLQSLLPQ-LLYC---RKLRLDTNQFQDPVM 40 50 60 70 80 440 450 460 470 480 FLJ003 EALSRSLPTMG-RLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRDNQLSDQVVLNI : :. : :.: ..:: ..:. .: . :...: . .: ...: :... : . . FLJ001 ELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKAL 90 100 110 120 130 140 490 500 510 520 530 540 FLJ003 VEVLPHLPRLRKLDLSSNSICVSTLLCLARVAVTCPTVRMLQAREADLIFLLSPPTETTA ...: : .:.:..:.. . .:.. .. :. ::. .. .. . . . FLJ001 ADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADAL 150 160 170 180 190 200 550 560 570 580 590 FLJ003 ELQRA-PDLQES-----DGQRKG-AQSRSLTLRLQKCQLQ---VHDA--EALIALLQEGP . .:. .:. : :: :. :.. ... :.. .:: . :: ::.. : . FLJ001 KQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQ 210 220 230 240 250 260 600 610 620 630 640 650 FLJ003 HLEEVDLSGNQLEDEGCRLMAEAASQLHIARKLDLSDNGLSVAGVHCVLRAVSACWTLAE : ..: :.. :: . .:.: ..:::. : : :.. . :: ::. FLJ001 TLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTS 270 280 290 300 310 320 660 670 680 690 700 710 FLJ003 LHISLQHKTVIFMFAQEPEEQKGPQERAAFLDSLMLQ---MPSELPLSSRRMRLTHCGLQ ::.. . :. : . . : :: :: . .. . : .. .: FLJ001 LHLQWN-----FIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALT 330 340 350 360 370 380 720 730 740 750 760 FLJ003 EKHLEQLCKALGGSCHLGHLH--------LDFSGNALGDEGAARLAQLLPGLGALQSLNL .:. . .:. ::. ::. :::.: :: ::. : ..:. ::: FLJ001 ALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNL 390 400 410 420 430 440 770 780 790 800 810 820 FLJ003 SENGLSLDAVLGLVRCFST-LQWLFRLD-ISFESQHILLRGDKTSRDMWATGSLPDFPAA .::.:..:... :..: :. ::. :.....:: ::. .: FLJ001 QENSLGMDGAI----CIATALSGNHRLQHINLQGNHI---GDSGARMISEAIKTNAPTCT 450 460 470 480 490 830 840 850 860 870 880 FLJ003 AKFLGFRQRCIPRSLCLSECPLEPPSLTRLCATLKDCPGPLELQLSCEFLSDQSLETLLD FLJ001 VEM >>FLJ00398 ( 660 res) sj06617 (660 aa) initn: 110 init1: 72 opt: 134 Z-score: 133.1 bits: 35.6 E(): 0.032 Smith-Waterman score: 370; 27.101% identity (54.412% similar) in 476 aa overlap (28-448:195-659) 10 20 30 40 FLJ003 SELLFDLYLSPESDHDTVFQYLEKNADQVLLIFDGLDEALQPMG---------PDGP ..:::.::::: :. : FLJ003 NTHEKLCADRLICSVFPHVGEPSLAVAVPARALLILDGLDECRTPLDFSNTVACTDPKKE 170 180 190 200 210 220 50 60 70 80 90 100 FLJ003 GPVLTLFSHLCNGTLLPGCRVMATSRP---GKLPACLPAEAAMVHMLGFDGPRVEEYVNH :: :.... :.:.: . :::: :..:. : . :... ::. ... ... FLJ003 IPVDHLITNIIRGNLFPEVSIWITSRPSASGQIPGGLVDR--MTEIRGFNEEEIKVCLEQ 230 240 250 260 270 280 110 120 130 140 150 160 FLJ003 FFSAQPSREG-ALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDHAPGQSVALLP--NM .: . . : : ..:.. : .:.:::.:... . : :: ... :.. : : .. FLJ003 MFPEDQALLGWMLSQVQADRALYLMCTVPAFCRLTGMALGHLWRSRTGPQDAELWPPRTL 290 300 310 320 330 340 170 180 190 200 FLJ003 TQLYMQMV-LALSPPG--------------HLLTSSLLDLGEVALRGLETGKVIFYAKDI .:: . .::: : : . . ::..:..:: : .:: .:. FLJ003 CELYSWYFRMALSGEGQEKGKASPRIEQVAHGGRKMVGTLGRLAFHGLLKKKYVFYEQDM 350 360 370 380 390 400 210 220 230 240 250 260 FLJ003 APPLIAFGATHSLL-----TSFCVRTGPGHQQTGYAFTHLSLQEFLAALHLM-ASPKVNK :::. .:: . : : ....: :::::::::.:: . . :: .. FLJ003 K----AFGVDLALLQGAPCSCFLQREETLASSVAYCFTHLSLQEFVAAAYYYGASRRAIF 410 420 430 440 450 270 280 290 300 FLJ003 DTLTQ---------YVTLHSRWVQRT-KARLGLSDHLPTFLAGLASCTCRPFL--SHLAQ : .:. ..: .::. .:. : : . ::.:: : .: : ::: FLJ003 DLFTESGVSWPRLGFLTHFRSAAQRAMQAEDGRLDVFLRFLSGLLSPRVNALLAGSLLAQ 460 470 480 490 500 510 310 320 330 340 350 360 FLJ003 GNEDCVGAKQAAVVQ-VLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPY-QLP :... .. : ..: :. :. . ..... ::. : :. ::: . ... : FLJ003 GEHQAYRTQVAELLQGCLRPDAA---VCARAINVLHCLHELQHTELARSVEEAMESGALA 520 530 540 550 560 570 370 380 390 400 410 420 FLJ003 FHNFPLTCTDLATLTNILEH--REAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKC . : . :: : .. . .:: . :... :. :. :. : ... . .. FLJ003 RLTGPAHRAALAYLLQVSDACAQEANLSLSLSQGVLQSLLPQ-LLYCRKLRWIPGQGAGA 580 590 600 610 620 630 430 440 450 460 470 480 FLJ003 GDAF---AEALSRSLPTMGRLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRDNQLS :.. :::. :... ...::: FLJ003 GEGAEERAEAVPSPPPSFS-VSLLGLP 640 650 660 >>FLJ00348 ( 778 res) sg00015 (778 aa) initn: 161 init1: 72 opt: 134 Z-score: 132.4 bits: 35.7 E(): 0.036 Smith-Waterman score: 414; 26.782% identity (54.721% similar) in 519 aa overlap (28-493:230-735) 10 20 30 40 FLJ003 SELLFDLYLSPESDHDTVFQYLEKNADQVLLIFDGLDEALQPMG---------PDGP ..:::.::::: :. : FLJ003 NTHEKLCADRLICSVFPHVGEPSLAVAVPARALLILDGLDECRTPLDFSNTVACTDPKKE 200 210 220 230 240 250 50 60 70 80 90 100 FLJ003 GPVLTLFSHLCNGTLLPGCRVMATSRP---GKLPACLPAEAAMVHMLGFDGPRVEEYVNH :: :.... :.:.: . :::: :..:. : . :... ::. ... ... FLJ003 IPVDHLITNIIRGNLFPEVSIWITSRPSASGQIPGGLVDR--MTEIRGFNEEEIKVCLEQ 260 270 280 290 300 310 110 120 130 140 150 160 FLJ003 FFSAQPSREG-ALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDHAPGQSVALLP--NM .: . . : : ..:.. : .:.:::.:... . : :: ... :.. : : .. FLJ003 MFPEDQALLGWMLSQVQADRALYLMCTVPAFCRLTGMALGHLWRSRTGPQDAELWPPRTL 320 330 340 350 360 370 170 180 190 200 FLJ003 TQLYMQMV-LALSPPG--------------HLLTSSLLDLGEVALRGLETGKVIFYAKDI .:: . .::: : : . . ::..:..:: : .:: .:. FLJ003 CELYSWYFRMALSGEGQEKGKASPRIEQVAHGGRKMVGTLGRLAFHGLLKKKYVFYEQDM 380 390 400 410 420 430 210 220 230 240 250 260 FLJ003 APPLIAFGATHSLL-----TSFCVRTGPGHQQTGYAFTHLSLQEFLAALHLM-ASPKVNK :::. .:: . : : ....: :::::::::.:: . . :: .. FLJ003 K----AFGVDLALLQGAPCSCFLQREETLASSVAYCFTHLSLQEFVAAAYYYGASRRAIF 440 450 460 470 480 490 270 280 290 300 FLJ003 DTLTQ---------YVTLHSRWVQRT-KARLGLSDHLPTFLAGLASCTCRPFL--SHLAQ : .:. ..: .::. .:. : : . ::.:: : .: : ::: FLJ003 DLFTESGVSWPRLGFLTHFRSAAQRAMQAEDGRLDVFLRFLSGLLSPRVNALLAGSLLAQ 500 510 520 530 540 550 310 320 330 340 350 360 FLJ003 GNEDCVGAKQAAVVQ-VLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPY-QLP :... .. : ..: :. :. . ..... ::. : :. ::: . ... : FLJ003 GEHQAYRTQVAELLQGCLRPDAA---VCARAINVLHCLHELQHTELARSVEEAMESGALA 560 570 580 590 600 610 370 380 390 400 410 420 FLJ003 FHNFPLTCTDLATLTNILEH--REAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKC . : . :: : .. . .:: . :... :. :. :. : ..: . . . FLJ003 RLTGPAHRAALAYLLQVSDACAQEANLSLSLSQGVLQSLLPQ-LLYC---RKLRLDTNQF 620 630 640 650 660 430 440 450 460 470 480 FLJ003 GDAFAEALSRSLPTMG-RLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRDNQLSDQ : : :. : :.: ..:: ..:. .: . :...: . .: ...: :... : FLJ003 QDPVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQ 670 680 690 700 710 720 490 500 510 520 530 540 FLJ003 VVLNIVEVLPHLPRLRKLDLSSNSICVSTLLCLARVAVTCPTVRMLQAREADLIFLLSPP . ....: FLJ003 GAKALADALKINRTLTSLRVKFMYHKIDCFRRVPEADACNPSTLGGQGRWIT 730 740 750 760 770 >>FLJ00240 ( 383 res) sj07454 (383 aa) initn: 196 init1: 105 opt: 119 Z-score: 120.8 bits: 32.6 E(): 0.16 Smith-Waterman score: 140; 23.235% identity (51.471% similar) in 340 aa overlap (399-727:9-324) 370 380 390 400 410 420 FLJ003 HNFPLTCTDLATLTNILEHREAPIHLDFDGCP-----LEPHCPEALVGCGQIE---NLSF :: : :: :. : :. .: FLJ002 LRHRLASRCPAPRLLLPPHLPQP--GSQQLLPQGSLHR 10 20 30 430 440 450 460 470 FLJ003 KSRKCGDAFAEALSRSLPTMGRLQMLGLAGSKITARGISHLVKALPLCPQLKEV--SFRD :.:. :: . .: . :. ..:...:. ... :...: : .:... .. . FLJ002 KGREAPPAFKQFFSSAYT----LSHVNLSATKLPLEALRALLQGLSLNSHLSDLHLDLSS 40 50 60 70 80 90 480 490 500 510 520 530 FLJ003 NQLSDQVVLNIVEVLPHLPRLRKLDLSSNSICVSTLLCLARVAVTCPTVRMLQAREADLI .: . . . : : . . .::::.:.. : :: :. . ... : . FLJ002 CELRSAGAQALQEQLGAVTCVGSLDLSDNGFD-SDLLTLVPALGKNKSLKHLFLGKN--- 100 110 120 130 140 540 550 560 570 580 590 FLJ003 FLLSPPTETTAELQRAPDLQESDGQRKGAQSRSLTLRLQKCQLQVHDAEALIALLQEGPH : .. : . . .:: : . .::.. .. .:.. :: : . FLJ002 FNVKAKTLEEILHKLVQLIQEED-----CSLQSLSVADSRLKLRTS---ILINALGSNTC 150 160 170 180 190 200 600 610 620 630 640 650 FLJ003 LEEVDLSGNQLEDEGCRLMAEAASQLHIARKLDLSD-NGLSVAGVHCVLRAVSACWTLAE : .:::::: .:: : .....: :.. . . : : :. :. : . ::. . :: FLJ002 LAKVDLSGNGMEDIGAKMLSKAL-QINSSLRTILWDRNNTSALGFLDIARALESNHTLR- 210 220 230 240 250 660 670 680 690 700 710 FLJ003 LHISLQHKTVIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKH .:. . . . . ::. . .. . :. . :. . . .:: . :: . FLJ002 -FMSFPVSDISQAYRSAPERTEDVWQKIQW--CLVRNNHSQTCPQEQAFRLQQ-GLVTSS 260 270 280 290 300 310 720 730 740 750 760 770 FLJ003 LEQLCKALGGSCHLGHLHLDFSGNALGDEGAARLAQLLPGLGALQSLNLSENGLSLDAVL ::. . : : FLJ002 AEQMLQRLCGRVQEEVRALRLCPLEPVQDELLYARDLIKDAKNSRAVSPPQATLPLKSGE 320 330 340 350 360 370 >>KIAA1234 ( 727 res) fh08618 (727 aa) initn: 99 init1: 47 opt: 120 Z-score: 118.8 bits: 33.1 E(): 0.2 Smith-Waterman score: 123; 24.090% identity (45.098% similar) in 357 aa overlap (6-338:391-719) 10 20 30 FLJ003 SELLFDLYLSPESDHDTVFQYLEKNADQVLLIFDG :: :.:.. :.. ..: .: KIAA12 GVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDR----EEEQHRMLSRASG 370 380 390 400 410 40 50 60 70 80 90 FLJ003 LDEALQPMGPDGPGPVLTLFSHLCNGT---LLPGCRVMATSRPGKLPACLPAEAAMVHML . . :: : : : .: .:. : :. . :: .::: .. KIAA12 VTGRRETPGPTKPLP-WTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQ---- 420 430 440 450 460 470 100 110 120 130 140 FLJ003 GFDGPRVEEYVNHFFSAQPSREGALVELQTNGRLRSLC---AVPALCQVACLCLHHLLPD : . ..: : .:: .. .:. .:.. . : ::. :.: ::. KIAA12 ---GTFRNSPISHPPSPSPSAYSS----RTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQ 480 490 500 510 520 150 160 170 180 190 200 FLJ003 HAPG-QSVAL--LPNMTQLYMQMVLALSPPGHLLTSSLLDLGEVALRGLETGKVIFYAKD :: : : : : .. .: : ::: : .:: .:... . . : KIAA12 --PGAQRFATRGYP-MEDMKLQGVPM--PPGDLCGPTLLL--DVSIKMEKDSGCEGAADG 530 540 550 560 570 210 220 230 240 250 260 FLJ003 IAPPLIAFGAT---H--SLLTSFCVRTGPGHQQTGYAFTHLSLQEFLAALHLMASPKVNK .: . .::. : .. : . ..: : .: : ..::. : : :. .. KIAA12 CVPSQVWLGASDRSHPATFPTRMHLKTEPDSRQQVY-ISHLGHGVRGAQPHGRATAGRSR 580 590 600 610 620 630 270 280 290 300 310 FLJ003 DTLTQYVTLHSRWVQRTKARLGLSDHLPTFLA-----GLASCTCR-----PFLSHLAQGN . :: . : .. : :: . : : ::::: : ... . KIAA12 E-LTPFHPAHCACLEPTD---GLPQSEPPHQLCARGRGEQSCTCRAAEAAPVVKREPLDS 640 650 660 670 680 690 320 330 340 350 360 370 FLJ003 EDCVGAKQAAVVQVLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNF . . .:. : .: : : :. :. KIAA12 PQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP 700 710 720 >>KIAA1835 ( 623 res) fh08795s1 (623 aa) initn: 147 init1: 80 opt: 119 Z-score: 118.5 bits: 32.8 E(): 0.21 Smith-Waterman score: 159; 23.545% identity (53.439% similar) in 378 aa overlap (410-769:54-396) 380 390 400 410 420 430 FLJ003 TLTNILEHREAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSR--KCGDAF-AEALSRS :. :: ::::.. : . : :. . . KIAA18 VCRSPGEPTSLVNMASEDIAKLAETLAKTQVAGGQ---LSFKGKSLKLNTAEDAKDVIKE 30 40 50 60 70 80 440 450 460 470 480 490 FLJ003 LPTMGRLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRD---NQLSDQVVLNIVEVL . . :. : : :. . ... ..::: .::. . : ..: .. .. . KIAA18 IEDFDSLEALRLEGNTVGVEAARVIAKALEKKSELKRCHWSDMFTGRLRTEIPPALISLG 90 100 110 120 130 140 500 510 520 530 540 FLJ003 PHL----PRLRKLDLSSNSIC---VSTLLCLARVAVTCPTVRMLQAREADLIFLLSPPTE : .: .::::.:.. :. . : . .. : :.. :. . . .. KIAA18 EGLITAGAQLVELDLSDNAFGPDGVQGFEALLKSSA-CFTLQELKLNNCGMG--IGGGKI 150 160 170 180 190 550 560 570 580 590 600 FLJ003 TTAELQRAPDLQESDGQRKG-AQSRSLTLRL---QKCQLQVHDAEALIALLQEGPHLEEV .: : .. .::. ::.. :.:.. . .:. : :: .. :::: KIAA18 LAAAL--------TECHRKSSAQGKPLALKVFVAGRNRLENDGATALAEAFRVIGTLEEV 200 210 220 230 240 610 620 630 640 650 660 FLJ003 DLSGNQLEDEGCRLMAEAASQLHIARKLDLSDNGLSVAGVHCVLRAVSACWTLAELHISL . : .. : .:.: . . : ..:.:: .. : ::. .:: .: KIAA18 HMPQNGINHPGITALAQAFAVNPLLRVINLNDNTFTEKG------AVA----MAETLKTL 250 260 270 280 290 670 680 690 700 710 720 FLJ003 QHKTVIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKHLEQLC .. :: :.. ..:: .:. :.. .: . ... :. : ... . KIAA18 RQVEVI-NFGDCLVRSKGA---VAIADAIRGGLP-----KLKELNLSFCEIKRDAALAVA 300 310 320 330 340 350 730 740 750 760 770 780 FLJ003 KALGGSCHLGHLHLDFSGNALGDEGAARLAQLLPGLGALQSL-NLSENGLSLDAVLGLVR .:.. . .: . ::..::.::.:: .: ..: :.. . : .::.. KIAA18 EAMADKAELEK--LDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEE 360 370 380 390 400 790 800 810 820 830 840 FLJ003 CFSTLQWLFRLDISFESQHILLRGDKTSRDMWATGSLPDFPAAAKFLGFRQRCIPRSLCL KIAA18 EEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPPPA 410 420 430 440 450 460 >>KIAA0980 ( 1406 res) hj07083 (1406 aa) initn: 116 init1: 63 opt: 115 Z-score: 110.8 bits: 32.6 E(): 0.56 Smith-Waterman score: 118; 24.701% identity (50.598% similar) in 251 aa overlap (365-610:1107-1345) 340 350 360 370 380 390 FLJ003 TGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFP----LTCTDLATLTNILEHREA .: :: . : .::. . . :: :. KIAA09 REKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAES 1080 1090 1100 1110 1120 1130 400 410 420 430 440 450 FLJ003 PIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLGLAG : : . .: . .:...: :. .... : ... : : .:: . KIAA09 T-H-DAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVL-------QLGQEA 1140 1150 1160 1170 1180 460 470 480 490 500 510 FLJ003 SKITARGISHLVKALPLCPQLKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSIC : :.. : : : .:.:: .: :::. ::. . ..:.: . . KIAA09 STHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSEL- 1190 1200 1210 1220 1230 1240 520 530 540 550 560 FLJ003 VSTLLCLARVAVTCPTVRMLQAREADLIFLLSPPTETTAELQRAPDLQESDGQRK-GAQS . : .. : .:. ::. : . : . .:::.: .:: ...:. :: KIAA09 -TQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQR 1250 1260 1270 1280 1290 1300 570 580 590 600 610 620 FLJ003 RSLTLRLQKCQLQVHDAEALIALLQEGPHLEEVDLSGNQLEDEGCRLMAEAASQLHIARK . .:. . .:..:: .. . : :.:: .:.: KIAA09 EEHEKQLKATEERVEEAEMILKNM-EMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHL 1310 1320 1330 1340 1350 1360 630 640 650 660 670 680 FLJ003 LDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQEPEEQKGPQERAAFLD KIAA09 VRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV 1370 1380 1390 1400 1056 residues in 1 query sequences 2209938 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 11:01:49 2009 done: Fri Feb 27 11:01:50 2009 Total Scan time: 0.840 Total Display time: 0.240 Function used was FASTA [version 34.26.5 April 26, 2007]