# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh04531.fasta.huge -Q ../query/FLJ00143.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00143, 373 aa vs ./tmplib.10216 library 2210621 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 5.9831+/-0.00528; mu= 9.1709+/- 0.356 mean_var=161.3583+/-35.028, 0's: 0 Z-trim: 4 B-trim: 0 in 0/40 Lambda= 0.100967 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA0975 ( 1528 res) hj06890 (1528) 166 36.4 0.015 KIAA0713 ( 945 res) hg04739 ( 945) 158 35.0 0.026 KIAA0488 ( 523 res) af14633 ( 523) 149 33.3 0.045 KIAA0113 ( 636 res) ha01652s1 ( 636) 127 30.2 0.46 KIAA0064 ( 495 res) ha01355 ( 495) 120 29.1 0.81 KIAA0389 ( 1296 res) hj00061 (1296) 123 30.1 1.1 KIAA0254 ( 1009 res) ha07011 (1009) 112 28.3 2.8 KIAA1071 ( 675 res) hj05664s2 ( 675) 108 27.5 3.3 KIAA1922 ( 370 res) fh11169 ( 370) 103 26.4 3.8 KIAA0471 ( 413 res) hg03220 ( 413) 103 26.5 4 FLJ00276 ( 426 res) sh00612 ( 426) 103 26.5 4.1 KIAA1026 ( 519 res) fh00114 ( 519) 103 26.6 4.6 KIAA1167 ( 834 res) hj01786(revised) ( 834) 105 27.2 5 KIAA0004 ( 1307 res) ha00065 (1307) 107 27.7 5.4 KIAA0674 ( 1234 res) hk02519 (1234) 106 27.5 5.8 KIAA1275 ( 1140 res) hk10413 (1140) 104 27.2 6.7 KIAA1565 ( 1313 res) bf00184 (1313) 104 27.3 7.3 KIAA1375 ( 546 res) fj04426 ( 546) 97 25.8 8.7 FLJ00045 ( 272 res) as00045 ( 272) 92 24.6 9.5 KIAA0949 ( 1559 res) af07325 (1559) 102 27.1 10 KIAA0445 ( 1919 res) hg00102s1 (1919) 103 27.4 10 KIAA0866 ( 1984 res) hk00546s1 (1984) 103 27.4 10 KIAA0648 ( 851 res) hj03994 ( 851) 97 26.0 11 KIAA1981 ( 862 res) fk03148(revised) ( 862) 97 26.0 12 KIAA1055 ( 868 res) hh09512 ( 868) 97 26.0 12 KIAA1361 ( 1005 res) fj02367 (1005) 97 26.1 13 KIAA1814 ( 1285 res) ph00952 (1285) 98 26.4 13 KIAA0989 ( 859 res) hk05377 ( 859) 95 25.7 14 FLJ00192 ( 1437 res) sj02564 (1437) 98 26.5 14 KIAA0234 ( 1512 res) ha02764 (1512) 98 26.5 15 KIAA0092 ( 475 res) ha01343 ( 475) 91 24.8 15 KIAA0981 ( 578 res) hj07094 ( 578) 92 25.1 15 FLJ00279 ( 563 res) sh01691 ( 563) 91 24.9 16 KIAA1937 ( 704 res) fk04595 ( 704) 91 25.0 19 KIAA1519 ( 648 res) fh13905s1 ( 648) 90 24.8 20 KIAA1454 ( 1265 res) fh15916 (1265) 94 25.8 20 FLJ00150 ( 1793 res) sh05613 (1793) 96 26.3 20 KIAA1189 ( 300 res) hg03032a ( 300) 85 23.7 20 KIAA0775 ( 639 res) hk05255 ( 639) 89 24.7 22 KIAA0483 ( 299 res) hj00879 ( 299) 84 23.5 23 FLJ00120 ( 1171 res) as00120 (1171) 92 25.5 23 KIAA1598 ( 446 res) fj09914 ( 446) 86 24.1 24 KIAA1764 ( 1029 res) fj10485(revised) (1029) 91 25.3 24 KIAA1124 ( 1760 res) fg05708 (1760) 94 26.0 24 KIAA0741 ( 1222 res) hk04024 (1222) 91 25.4 26 KIAA1145 ( 467 res) hk10430 ( 467) 85 23.9 27 KIAA0665 ( 760 res) hk02064 ( 760) 87 24.5 29 KIAA1131 ( 2168 res) pf08614 (2168) 93 26.0 30 KIAA1641 ( 718 res) fj10609s1 ( 718) 86 24.3 31 FLJ00230 ( 414 res) sj06557 ( 414) 82 23.4 33 >>KIAA0975 ( 1528 res) hj06890 (1528 aa) initn: 165 init1: 90 opt: 166 Z-score: 138.9 bits: 36.4 E(): 0.015 Smith-Waterman score: 166; 30.233% identity (69.767% similar) in 86 aa overlap (233-318:52-136) 210 220 230 240 250 260 FLJ001 EDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLH ... :: . . . ::.. .::..:..:: KIAA09 DPNMATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLH 30 40 50 60 70 80 270 280 290 300 310 320 FLJ001 HKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKK .:: . .. .:::: ::... ..::.:.:.:. ::.... ..:. : KIAA09 EKLVAER-KIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLH 90 100 110 120 130 140 330 340 350 360 370 FLJ001 ETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRNVEPQSGDL KIAA09 FHFYEINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTD 150 160 170 180 190 200 >>KIAA0713 ( 945 res) hg04739 (945 aa) initn: 62 init1: 62 opt: 158 Z-score: 134.9 bits: 35.0 E(): 0.026 Smith-Waterman score: 158; 26.154% identity (64.615% similar) in 130 aa overlap (197-317:606-734) 170 180 190 200 210 220 FLJ001 ERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVF :::..: :.:.. . .. . : . KIAA07 LKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSNVSSDDSVQLHAYISDTVYADYDPYAV 580 590 600 610 620 630 230 240 250 260 270 FLJ001 L-----RGKAANAFHVYQVYIRIKDDE--WNIYRRYTEFRSLHHKLQNKYPQVRAY-NFP .::. :... :. : ..: :. ::::..:...: .. ... .. . ..: KIAA07 AGVCNDHGKTY-ALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKLP 640 650 660 670 680 690 280 290 300 310 320 330 FLJ001 PKKAIGNKDAKFVEERRKQLQNYLRSVMN-KVIQMVPEFAASPKKETLIQLMPFFVDITP ::...: : :.:.:.:.:. ::. .. .... : .: KIAA07 EKKTFNNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKGKGDFA 700 710 720 730 740 750 340 350 360 370 FLJ001 PGEPVNSRPKAASRFPKLSRGQPRETRNVEPQSGDL KIAA07 RKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTKMSDNMGKMSERLGQDIKQSFFKVPPL 760 770 780 790 800 810 >>KIAA0488 ( 523 res) af14633 (523 aa) initn: 89 init1: 63 opt: 149 Z-score: 130.6 bits: 33.3 E(): 0.045 Smith-Waterman score: 149; 24.803% identity (53.150% similar) in 254 aa overlap (115-350:54-290) 90 100 110 120 130 FLJ001 MKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQK-----PGE ::..: .: :..::. . :. :: KIAA04 HCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGG 30 40 50 60 70 80 140 150 160 170 180 190 FLJ001 IAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPG--- :.. . ...:: ... : :. .: :. ..::: :: KIAA04 AADRAGVRKGDRILEVNHVNVEGAT-----HKQVVD---LIRAGEKELILTVLSVPPHEA 90 100 110 120 130 200 210 220 230 240 250 FLJ001 ---DLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYR : :. : ::. :. ... . . .: . .. : ::.::. .. . KIAA04 DNLDPSDDSLGQSFYDY--TEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQ---LCSK 140 150 160 170 180 190 260 270 280 290 300 310 FLJ001 RYTEFRSLHHKLQNKYPQVRAYNFP--PKKAIGNKDAKFVEERRKQLQNYLRSVMN-KVI :: :: ::..:. .. . ..:: : : . . . .. ::. :..::..: . .:: KIAA04 RYREFAILHQNLKREFAN---FTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVI 200 210 220 230 240 320 330 340 350 360 FLJ001 ---QMVPEF-AASPKKETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRNV ... :: . : .. . .. . . : . : : :. : : : KIAA04 GESDIMQEFLSESDENYNGVSDVELRVAL-PDGTTVTVRVKKNSTTDQVYQAIAAKVGMD 250 260 270 280 290 300 370 FLJ001 EPQSGDL KIAA04 STTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLN 310 320 330 340 350 360 >>KIAA0113 ( 636 res) ha01652s1 (636 aa) initn: 56 init1: 56 opt: 127 Z-score: 112.4 bits: 30.2 E(): 0.46 Smith-Waterman score: 133; 22.015% identity (60.448% similar) in 268 aa overlap (65-311:215-470) 40 50 60 70 80 90 FLJ001 VAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQALAREN ::.: ..:: :. . :.. . .. : .:: KIAA01 GRMALEFNRLASKVHKNEQRTSILQTLCEQLRKENEALKAKLDKGLEQRDQAAERLREEN 190 200 210 220 230 240 100 110 120 130 140 FLJ001 EVLKVQLKKYVGAVQMLKREGQTAE--VPNLWSVDGEVTVAEQKP----GEIAEELA-SS ..::: . .. ..:: ... :.. .. ......:. :.. : .: .. KIAA01 ----LELKKLL--MSNGNKEGASGRPGSPKMEGTGKKAVAGQQQASVTAGKVPEVVALGA 250 260 270 280 290 150 160 170 180 190 200 FLJ001 YERKLIEVAEMHGELIEFNERL--H-RALVAK-EALVSQMRQELIDLRGPVPGDLSQTSE :.:. . ....::.: :.. : :.. . : ....::.: ::. : :: .. . KIAA01 AEKKVKMLEQQRSELLEVNKQWDQHFRSMKQQYEQKITELRQKLADLQKQVT-DL-EAER 300 310 320 330 340 350 210 220 230 240 250 FLJ001 DQSLSDFEISNRALI----NVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFR .:. ::. : :. .. . . . .:.: .. : .. .:. . : :.. KIAA01 EQKQRDFD---RKLLLAKSKIEMEETDKEQLTAEAKELRQ-KVKYLQDQLSPLTRQREYQ 360 370 380 390 400 410 260 270 280 290 300 310 FLJ001 SLH-HKLQNKYPQVRAYNFPPKK---AIGNKDAKFVEERRKQL--QNYLRSVMNKVIQMV . ..:.. .. . . ::.. :.:. .. . :...: :: : . . :... KIAA01 EKEIQRLNKALEEALSIQTPPSSPPTAFGSPEGAGALLRKQELVTQNELLKQQVKIFEED 420 430 440 450 460 470 320 330 340 350 360 370 FLJ001 PEFAASPKKETLIQLMPFFVDITPPGEPVNSRPKAASRFPKLSRGQPRETRNVEPQSGDL KIAA01 FQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQLKAFKDEEKAREALRQQKRKAKASG 480 490 500 510 520 530 >>KIAA0064 ( 495 res) ha01355 (495 aa) initn: 120 init1: 74 opt: 120 Z-score: 108.0 bits: 29.1 E(): 0.81 Smith-Waterman score: 120; 38.462% identity (75.000% similar) in 52 aa overlap (254-305:61-111) 230 240 250 260 270 280 FLJ001 SVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAI ::... .::..:...: ::::: . KIAA00 PETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFPPKKLF 40 50 60 70 80 90 290 300 310 320 330 340 FLJ001 GNKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQLMPFFVDITPPGEPVN . :. ::.::.::..:...: KIAA00 SLTPAE-VEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLEVLLS 100 110 120 130 140 >>KIAA0389 ( 1296 res) hj00061 (1296 aa) initn: 93 init1: 41 opt: 123 Z-score: 105.9 bits: 30.1 E(): 1.1 Smith-Waterman score: 123; 25.786% identity (57.233% similar) in 159 aa overlap (35-193:921-1072) 10 20 30 40 50 60 FLJ001 SPGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAA .. ...: . ::: . :: . . :::. KIAA03 TLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQE-EMEKERK 900 910 920 930 940 70 80 90 100 110 120 FLJ001 LRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLW :.: : .:. :.:.:. ....: ...: . . . .: . :.: :. . KIAA03 RREE-DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQA-EVEAQLARQKEEE 950 960 970 980 990 1000 130 140 150 160 170 180 FLJ001 SVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMR : . : :.. :.: ..:.: : .:: : ...: . : .. : ....: KIAA03 SQQQAVLEQERRDRELALRIAQS-EAELIS-DEAQADLALRRNDGTRPKMTPEQMAKEMS 1010 1020 1030 1040 1050 1060 190 200 210 220 230 240 FLJ001 QELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRI . : ::: KIAA03 EFLS--RGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVY 1070 1080 1090 1100 1110 1120 >>KIAA0254 ( 1009 res) ha07011 (1009 aa) initn: 63 init1: 53 opt: 112 Z-score: 98.4 bits: 28.3 E(): 2.8 Smith-Waterman score: 112; 32.558% identity (59.302% similar) in 86 aa overlap (251-328:596-675) 230 240 250 260 270 FLJ001 WIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAY--NFP . ::: :: .:. .:..: :..: . : KIAA02 FHPYTLYTVKYETALDGENSSGLQQLAYHTVNRRYREFLNLQTRLEEK-PDLRKFIKNVK 570 580 590 600 610 620 280 290 300 310 320 330 FLJ001 -PKK-----AIGNKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQLMPFF ::: .:: :. :: :.. :...: : . .::.: : . . .. : KIAA02 GPKKLFPDLPFGNMDSDRVEARKSLLESFL-----KQLCAIPEIANSEEVQEFLALNTDA 630 640 650 660 670 340 350 360 370 FLJ001 VDITPPGEPVNSRPKAASRFPKLSRGQPRETRNVEPQSGDL KIAA02 RIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETESKPQTEGKKASK 680 690 700 710 720 730 >>KIAA1071 ( 675 res) hj05664s2 (675 aa) initn: 106 init1: 57 opt: 108 Z-score: 97.1 bits: 27.5 E(): 3.3 Smith-Waterman score: 111; 23.077% identity (59.135% similar) in 208 aa overlap (16-191:1-205) 10 20 30 40 50 FLJ001 VEASSPGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEE----ENRSLRNLLD .: :. : : . . . :...: ... : :::.::. :. KIAA10 MPRAQ-PSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELE 10 20 30 40 60 70 80 90 100 FLJ001 GEMEHSAALRQEVDTLKRKVAEQEE---RQGMKVQALAR------ENEVLKVQ-----LK : .:. : : :.:.: ..:.: : ... : .:: . :.:. ... :. KIAA10 GCYEKVARL-QKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLR 50 60 70 80 90 100 110 120 130 140 150 FLJ001 KYVGAV--QMLKREGQTAE-----VPNLWSVDGEVTVAEQK-PGEIAEELASSYE-RKLI . . .. :. ..: . .: . .:.. . : ..: .:.: ... . :. : KIAA10 ERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHI 110 120 130 140 150 160 160 170 180 190 200 FLJ001 EVAEM-----HGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLS :. .. ........:.:.. : . : .:.: :..:. KIAA10 EIRDQALSNAQAKVVKLEEELKKKQVYVDK-VEKMQQALVQLQAACEKREQLEHRLRTRL 170 180 190 200 210 220 210 220 230 240 250 260 FLJ001 DFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNK KIAA10 ERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVM 230 240 250 260 270 280 >>KIAA1922 ( 370 res) fh11169 (370 aa) initn: 98 init1: 58 opt: 103 Z-score: 96.0 bits: 26.4 E(): 3.8 Smith-Waterman score: 113; 24.365% identity (57.868% similar) in 197 aa overlap (4-191:45-232) 10 20 30 FLJ001 VEASSPGHG-SPLSSLLPSASVPESMTISELRQ ::::.: :: . :: . .: :.. : . KIAA19 QLSGSKRTADDSFGSLRGLSAQQTPSPPRRSSPGRGRSPRRG--PSPACSDSSTLA-LIH 20 30 40 50 60 70 40 50 60 70 80 FLJ001 ATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEV---DTLKRKVAEQEERQGMKVQA .:. .: ::. .. .:. .. .. ..::... .. .: . :: .: :... KIAA19 STL----HKHELQVQD--MRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDS 80 90 100 110 120 90 100 110 120 130 140 FLJ001 LARENEVLKVQLKKYVGAVQMLKRE-GQTAEVPNLWSVDGEVTVAEQKPGEIAEELASSY . .: . .... .: ..:.:: .. :. .. . ... :.: . :.: KIAA19 TMQAHEDAQREVQRLRSAKELLRREKSNLAHSLQVAQQQAKELRQERKKLQAAQEELRRQ 130 140 150 160 170 180 150 160 170 180 190 200 FLJ001 ERKLIEVAE---MHGELIEFN-ERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSED . : : : . : .. . :: :: : :. : . .::...: KIAA19 RYWLGEEQEDAVQDGVRVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 190 200 210 220 230 240 210 220 230 240 250 260 FLJ001 QSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHK KIAA19 QAEKAEVAEALTKAEGRGGLPAGLPVQAERPQREPCSGQVGSEPPCHPGHSWRKKSAPCR 250 260 270 280 290 300 >>KIAA0471 ( 413 res) hg03220 (413 aa) initn: 92 init1: 92 opt: 103 Z-score: 95.5 bits: 26.5 E(): 4 Smith-Waterman score: 103; 28.205% identity (67.949% similar) in 78 aa overlap (30-103:179-256) 10 20 30 40 50 FLJ001 VEASSPGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEE----NRSLRNLL :..:.. . ...:.: .: . .::: : KIAA04 KKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDL 150 160 170 180 190 200 60 70 80 90 100 110 FLJ001 DGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREG : ... .: .:. :....: ::.. . . :. .::.. ::.: KIAA04 DQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAII 210 220 230 240 250 260 120 130 140 150 160 170 FLJ001 QTAEVPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVA KIAA04 AEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGI 270 280 290 300 310 320 373 residues in 1 query sequences 2210621 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:41:37 2009 done: Fri Feb 27 10:41:38 2009 Total Scan time: 0.490 Total Display time: 0.070 Function used was FASTA [version 34.26.5 April 26, 2007]