# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh04538.fasta.huge -Q ../query/FLJ00362.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00362, 638 aa vs ./tmplib.10216 library 2210356 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 6.1280+/-0.00656; mu= 16.7778+/- 0.442 mean_var=266.1567+/-60.988, 0's: 0 Z-trim: 2 B-trim: 156 in 1/39 Lambda= 0.078615 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 38, opt: 26, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1088 ( 1400 res) hk02589s1 (1400) 2954 348.7 2.4e-96 KIAA0522 ( 1555 res) hg01393 (1555) 166 32.6 0.38 FLJ00084 ( 641 res) as00084 ( 641) 144 29.4 1.4 KIAA0582 ( 760 res) fh15957 ( 760) 142 29.3 1.8 KIAA1048 ( 897 res) hh02560 ( 897) 133 28.4 3.9 FLJ00253 ( 349 res) sj09455 ( 349) 127 27.0 4 KIAA0755 ( 1093 res) hk04532 (1093) 132 28.4 4.7 KIAA0999 ( 1371 res) fj10213 (1371) 133 28.7 4.8 KIAA1860 ( 689 res) fh18358 ( 689) 128 27.7 5.1 FLJ00201 ( 705 res) sj04110 ( 705) 127 27.6 5.6 KIAA1332 ( 651 res) fh15405 ( 651) 126 27.4 5.8 KIAA1836 ( 718 res) fh12206(revised) ( 718) 126 27.5 6.1 KIAA1172 ( 929 res) hj03919(revised) ( 929) 123 27.3 8.8 KIAA0910 ( 1315 res) hg02207s1 (1315) 125 27.8 8.9 KIAA1249 ( 949 res) hh04184 ( 949) 123 27.3 8.9 KIAA2009 ( 501 res) fj05611 ( 501) 119 26.4 8.9 KIAA0574 ( 405 res) hj00204 ( 405) 117 26.0 9.4 KIAA1743 ( 1036 res) pj01380s1 (1036) 122 27.3 10 KIAA1802 ( 821 res) fj21631 ( 821) 120 26.9 10 KIAA1582 ( 1740 res) fj05982s1 (1740) 124 27.9 11 KIAA0482 ( 1332 res) hj01880 (1332) 122 27.5 11 KIAA0298 ( 901 res) hf00341(revised) ( 901) 119 26.8 12 KIAA0881 ( 1064 res) hk07534 (1064) 120 27.1 12 KIAA0306 ( 1451 res) hg00063 (1451) 121 27.4 13 KIAA0665 ( 760 res) hk02064 ( 760) 117 26.5 13 KIAA0900 ( 503 res) hk09606s1 ( 503) 113 25.7 14 KIAA1511 ( 1253 res) fg04486(revised) (1253) 118 27.0 15 KIAA0377 ( 1412 res) hh00412 (1412) 118 27.1 16 KIAA1147 ( 451 res) pf02131 ( 451) 111 25.4 16 KIAA0712 ( 1770 res) hg04169 (1770) 118 27.2 18 KIAA1994 ( 1117 res) bh00052 (1117) 115 26.5 18 KIAA0226 ( 973 res) fg02838 ( 973) 114 26.3 18 KIAA1297 ( 2242 res) fg03883 (2242) 118 27.4 20 KIAA1862 ( 1070 res) aj00563 (1070) 113 26.3 21 KIAA1813 ( 673 res) ph00819b ( 673) 110 25.6 21 KIAA0552 ( 709 res) hh00869 ( 709) 110 25.6 21 KIAA1811 ( 715 res) ha06731 ( 715) 110 25.6 21 KIAA1744 ( 855 res) pj01516 ( 855) 111 25.9 22 KIAA1609 ( 473 res) fj11503 ( 473) 107 25.0 22 KIAA1868 ( 463 res) fj22550 ( 463) 106 24.9 24 KIAA1142 ( 467 res) hh05864 ( 467) 106 24.9 24 KIAA0886 ( 1233 res) hk07722 (1233) 111 26.2 26 KIAA0176 ( 265 res) ha03941 ( 265) 101 23.9 27 KIAA0753 ( 979 res) hk04444 ( 979) 108 25.6 29 KIAA1935 ( 441 res) fk03135(revised) ( 441) 102 24.4 32 KIAA0208 ( 748 res) ha02713 ( 748) 105 25.1 32 KIAA0179 ( 762 res) ha02738 ( 762) 105 25.1 33 FLJ00277 ( 357 res) sh01540 ( 357) 100 24.0 34 KIAA0458 ( 1552 res) ef01252 (1552) 109 26.1 34 KIAA1614 ( 1208 res) fj12973 (1208) 107 25.7 35 >>KIAA1088 ( 1400 res) hk02589s1 (1400 aa) initn: 3126 init1: 2953 opt: 2954 Z-score: 1823.2 bits: 348.7 E(): 2.4e-96 Smith-Waterman score: 2957; 76.303% identity (83.361% similar) in 595 aa overlap (65-638:720-1300) 40 50 60 70 80 90 FLJ003 HVPWLLGRTGWCPGRAGAIRKWVAAEGPGLARAWVGSAWAAPALVSTFPYWSGVCREMGT ::: . : :. : : .. .. : :... KIAA10 AVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPS-WVRPH-VRVYDNFGHVIRDVAQ 690 700 710 720 730 740 100 110 120 130 140 FLJ003 AHPEAPPCALPSWEPQPHPLWGRGLEGGGERRAMQDPWLEAEPIYPLPIHCSQF------ : ..:. :. :: .. .: .. :.. .. : .: .. KIAA10 FFRVAER-TMPAPAPRATAPSVRGEDAVSEAKS-PGPFFSTRKAKSLDLHVPSLKQRSSG 750 760 770 780 790 800 150 160 170 180 190 200 FLJ003 -PAS----LSLCDLRRAQPHSFLPAA--PPYVHPASQFLRQQPHLGSHCPRERSMFQGRL ::. ::: . .: .:: : . : . .:. :: : :. :.. KIAA10 SPAAGDPESSLCVEYEQEP---VPARQRPRGLLAALEHSEQRA--GS--PGEE---QAHS 810 820 830 840 850 210 220 230 240 250 FLJ003 CSPRDQMM-RLALMEPRACVLQ-------EEPVAGAQTDRAKLFMVAVKQELSQANFATF :: . . . :::. . ::::::::::::::::::::::::::::::: KIAA10 CSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATF 860 870 880 890 900 910 260 270 280 290 300 310 FLJ003 TQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA10 TQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRG 920 930 940 950 960 970 320 330 340 350 360 370 FLJ003 CGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA10 CGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPP 980 990 1000 1010 1020 1030 380 390 400 410 420 430 FLJ003 TGDPGSHPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA10 TGDPGSHPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKV 1040 1050 1060 1070 1080 1090 440 450 460 470 480 490 FLJ003 LAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA10 LAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAV 1100 1110 1120 1130 1140 1150 500 510 520 530 540 550 FLJ003 PPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA10 PPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAAS 1160 1170 1180 1190 1200 1210 560 570 580 590 600 610 FLJ003 EWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA10 EWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQA 1220 1230 1240 1250 1260 1270 620 630 FLJ003 SRMCPACHTASRKQSVMQVFWPEPQ ::::::::::::::::::::::::. KIAA10 SRMCPACHTASRKQSVMQVFWPEPHKDHEGAGGARPVAAVPGVGAACPAAGAGCTRSGRN 1280 1290 1300 1310 1320 1330 >>KIAA0522 ( 1555 res) hg01393 (1555 aa) initn: 155 init1: 70 opt: 166 Z-score: 113.9 bits: 32.6 E(): 0.38 Smith-Waterman score: 166; 22.979% identity (48.511% similar) in 235 aa overlap (294-520:1323-1549) 270 280 290 300 310 320 FLJ003 DDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIP : : ..... . : .: : : .: KIAA05 GQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYC-QGPGPAPPPYLP 1300 1310 1320 1330 1340 1350 330 340 350 360 370 380 FLJ003 RRQRAQPVLDPTGRTAPDPKLTV---STAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSH .: . : : . : :.: :.: . :..:.. : .:. : :: KIAA05 PQQPSLP--PPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRA 1360 1370 1380 1390 1400 390 400 410 420 430 FLJ003 PQWGSGV-PRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAA :. :.: :. . .:.: . . . : : . .. : . :. . . :: KIAA05 PRRGAGGHPQFAPHGRHPL--HQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAA 1410 1420 1430 1440 1450 1460 440 450 460 470 480 490 FLJ003 LTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRP-YPGMEPPGPQEERLAVPPVLT ... : . : .: .::: : . . . .: :: . ::.:. . .::. KIAA05 GAAGGPGSRPPGGSYS---HPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSP 1470 1480 1490 1500 1510 1520 500 510 520 530 540 550 FLJ003 H---RAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEW : .: : . . ... ..: : KIAA05 HGPLHASGPPGTANPPSANPKAKPSRISTVV 1530 1540 1550 >>FLJ00084 ( 641 res) as00084 (641 aa) initn: 123 init1: 71 opt: 144 Z-score: 103.7 bits: 29.4 E(): 1.4 Smith-Waterman score: 169; 25.633% identity (46.519% similar) in 316 aa overlap (296-579:283-592) 270 280 290 300 310 320 FLJ003 FAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFE-EVCIQLTGRGCGYRPEHSIPR : :. . . ..: ..: : : :: FLJ000 QDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPR 260 270 280 290 300 310 330 340 350 360 370 380 FLJ003 RQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSHPQWG . : . : :. : . . :.:.: .. . .:: : : .:: :: . FLJ000 SVEPQDA-GPLERSQGDEAGGHGEDRPEPLSPKES-KKRKLELSRREQPPTEPG--PQSA 320 330 340 350 360 390 400 410 420 430 FLJ003 SGVPRAGK--QGQHAVSAYLADARRALGSAG-------CSQLLAALTAYK--QDDDLDKV : : . . .: .. : . . .:. : : :.: .: : . .:. FLJ000 SEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEG 370 380 390 400 410 420 440 450 460 470 480 490 FLJ003 LAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPG-PQEERLA . ::.... . . : . .:. . . . : :: : :: :.: FLJ000 AGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGP 430 440 450 460 470 480 500 510 520 530 540 FLJ003 VP--PVLTHRA--PQ--PGPSRSEKTGKTQSKISSFLR-QRPAGTVGAGGEDAG-PSQSS : :. . : :. ::: . .: .. : :::: :: : : ::.. FLJ000 SPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGP--AGDEPAKTPSETP 490 500 510 520 530 540 550 560 570 580 590 FLJ003 GP-PHGPAASEWGE-------PHGRDIAGQQATGAPG---GPLSAGCVCQGCGAEDVVPF :: : ::. .: .: :. ::.. . .:. :: :: FLJ000 GPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 550 560 570 580 590 600 600 610 620 630 FLJ003 QCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ FLJ000 GPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP 610 620 630 640 >>KIAA0582 ( 760 res) fh15957 (760 aa) initn: 80 init1: 51 opt: 142 Z-score: 101.8 bits: 29.3 E(): 1.8 Smith-Waterman score: 176; 23.826% identity (46.261% similar) in 575 aa overlap (43-574:41-556) 20 30 40 50 60 FLJ003 GVIAGARKPPACWKTPSVAAFVHVPWLLGRTGWCPGR----AGAIRKWVAAEGPGLARAW .: : : .: : .::: : KIAA05 AEAEASEDTKAQSYGRGSCRERELDIPGPMSGEQPPRLEAEGGLISPVWGAEGIPAPTCW 20 30 40 50 60 70 70 80 90 100 110 120 FLJ003 VGSAWAAPALVSTFPYWSGVCREMGTAHPEAPPCALPSWEPQPHPLWGRGLEGGGERRAM .:. ..:. . : : . :: . . : .:: : . . : .:: .. KIAA05 IGTDPGGPSRAHQ-PQASDANREPVAERSEPALSGLP-----PATMGSGDLLLSGESQVE 80 90 100 110 120 130 140 150 160 170 180 FLJ003 QDPWLEAEPIYPLPIHCSQFPASLSLCDLRRAQPHSFLPAAPPYVHPASQFLRQQPHL-G . .: .: . ..: . ..:. . :. .. :. : . : :::: : KIAA05 KTKLSSSEE-FPQTL---SLPRTTTICSGHDADTED-DPSLADL--PQALDLSQQPHSSG 130 140 150 160 170 190 200 210 220 230 240 FLJ003 SHCPRE-RSMFQ-GRLCSPRDQMMRLALMEPRACVLQE--EPVAGAQTDRAKLFMVAVKQ : . .:... : .: . . . :: :: .:. . .. . .: : KIAA05 LSCLSQWKSVLSPGSAAQPSSCSISASSTGSSLQGHQERAEPRGGSLAKVSSSLEPVVPQ 180 190 200 210 220 230 250 260 270 280 FLJ003 ELSQA-NFATFTQALQD--YKGSD---------DFAA-LAACLGP-LFAEDPKKHNLLQG : :.. ... : . ..:.: .: : ::. : . .: .:. : . KIAA05 EPSSVVGLGPRPQWSPQPVFSGGDASGLGRRRLSFQAEYWACVLPDSLPPSPDRHSPLWN 240 250 260 270 280 290 290 300 310 320 330 FLJ003 FYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPR----RQRAQPVLDPTG------RTA :. ...:. : :: ..:. : :.:::. .: .. KIAA05 ------PN--KEYED----LLDYTYPLRPGPQLPKHLDSRVPADPVLQDSGVDLDSFSVS 300 310 320 330 340 340 350 360 370 380 390 FLJ003 PDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSHPQWGSGVPRAGKQGQHAVS : : : .. . : : . : .:: : : :: : ::. ::: ... KIAA05 PASTLKSPTNVSPNCPPAE--ATALPFSGPREP------SLKQWPSRVPQ--KQGGMGLA 350 360 370 380 390 400 410 420 430 440 450 FLJ003 AY--LADARRALGS--AGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFS .. ::.. :: :: : . :: . :. . : : . . .. . .: KIAA05 SWSQLASTPRAPGSRDARWERREPALRGAKDRLTIGKHLDMGSPQLRTRDRGWPS----- 400 410 420 430 440 450 460 470 480 490 500 510 FLJ003 MFVRPHHKQRFSQ-----TCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSE ::....: :: :::. . .: ..: ::.: ::. . : KIAA05 --PRPEREKRTSQSARRPTCTESRWKSEEEVES---DDEYLALPARLTQVS-----SLVS 460 470 480 490 500 520 530 540 550 560 FLJ003 KTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGE-PHGRDIAGQQAT :. ::... :.: . : :.:.:: :..: .. : : :. :.. KIAA05 YLGS----ISTLVTL-PTGDI-KGQSPLEVSDSDGPASFPSSSSQSQLPPG---AALQGS 510 520 530 540 550 570 580 590 600 610 620 FLJ003 GAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSV : : : KIAA05 GDPEGQNPCFLRSFVRAHDSAGEGSLGSSQALGVSSGLLKTRPSLPARLDRWPFSDPDVE 560 570 580 590 600 610 >>KIAA1048 ( 897 res) hh02560 (897 aa) initn: 79 init1: 71 opt: 133 Z-score: 95.7 bits: 28.4 E(): 3.9 Smith-Waterman score: 153; 23.162% identity (50.000% similar) in 272 aa overlap (329-572:419-682) 300 310 320 330 340 350 FLJ003 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTA--PDPKLTVST------AA ::.: : :.. : :. . :. :. KIAA10 DPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLAS 390 400 410 420 430 440 360 370 380 390 400 FLJ003 AQQLDPQEHLNQGRPHLS---PRPPPTGDPGSHPQ-WGSGVP-RAGKQGQHAVSAYLADA . : :: .: :. . :. ::: : . :. ..:.: .: :: . .: . KIAA10 VPQPKPQAPPSQPLPQTQAKQPQAPPT--PQQTPSTQAQGLPAQAQATPQHQQQLFLKQQ 450 460 470 480 490 500 410 420 430 440 450 FLJ003 RRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHR-------FSMFV .. .: :. .:. . .. :: : .::.. . .. : KIAA10 QQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFY 510 520 530 540 550 560 460 470 480 490 500 510 FLJ003 RPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTH-RAPQPGPSRSEKTGKTQS . ...:. .: .:. . .. :. : :... . ::: :. . . . .: KIAA10 QQQQQQQQQQQQQQLATALH--QQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQE 570 580 590 600 610 620 520 530 540 550 560 570 FLJ003 K-ISSFLRQRPAGTVGAGGEDAGPSQSSG---PPHGPAASEWGEPHGR---DIAGQQATG :.. .::.: : . : .:. : :: .: ... : : : :.. . . : KIAA10 PAIQAPVRQQP--KVQTTPPPAVQGQKVGSLTPPSSPKTQRAG--HRRILSDVTHSAVFG 630 640 650 660 670 680 580 590 600 610 620 630 FLJ003 APGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVM .: KIAA10 VPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKL 690 700 710 720 730 740 >>FLJ00253 ( 349 res) sj09455 (349 aa) initn: 115 init1: 59 opt: 127 Z-score: 95.6 bits: 27.0 E(): 4 Smith-Waterman score: 129; 27.660% identity (50.355% similar) in 141 aa overlap (473-605:129-263) 450 460 470 480 490 FLJ003 AKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVP-----PVL . : .: .::: : : . : :. FLJ002 SSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPP-QPPGSQSESSSHPALSQSPMP 100 110 120 130 140 150 500 510 520 530 540 550 FLJ003 THRAPQPGPSRSEKT---GKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASE .:. . : .:. . : :. : . :.: . :: . :.::: .:: :. FLJ002 QERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGT-YGPQMSQ 160 170 180 190 200 210 560 570 580 590 600 610 FLJ003 WGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQAS .: :.: .:.:.. :. .: .:.. . : :. : : : FLJ002 YG-PQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPS---QPCGAVPLGRMPSA 220 230 240 250 260 270 620 630 FLJ003 RMCPACHTASRKQSVMQVFWPEPQ FLJ002 GMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRYA 280 290 300 310 320 330 >>KIAA0755 ( 1093 res) hk04532 (1093 aa) initn: 213 init1: 97 opt: 132 Z-score: 94.3 bits: 28.4 E(): 4.7 Smith-Waterman score: 137; 20.520% identity (45.665% similar) in 346 aa overlap (309-628:62-390) 280 290 300 310 320 330 FLJ003 EDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRT .. .: : .: : : . . : KIAA07 AEPPALGSPRGAGAGTDFFCRIILWNDIFIMSQQGYVATPPYSQP--QPGIGLSPPHYGH 40 50 60 70 80 340 350 360 370 380 FLJ003 APDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTG-----DPGSH-----PQWGSGVP ::. :.: .. .. . : : : ::: : . :.: :: : : KIAA07 YGDPSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPP 90 100 110 120 130 140 390 400 410 420 430 FLJ003 RAGK-QGQHAVSAYLADARRA----LGSAGCSQLLAALTAYKQDDDLDKV---------- ... ..:: : .:. . ..... .:: . :.:.. .. . . KIAA07 PVNNVASSHA--PYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPGP 150 160 170 180 190 200 440 450 460 470 480 490 FLJ003 LAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAV :.. . : .: . .:. :. . : . . : : : ..: : . . KIAA07 LSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPL---PLPMYRPDGLS----GP 210 220 230 240 250 260 500 510 520 530 540 550 FLJ003 PPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAAS :: .. : : :... .: .. .: .. : :: .::.: .:::. KIAA07 PPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKL 270 280 290 300 310 320 560 570 580 590 600 610 FLJ003 EWGE-PHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQ . : .. .. .. :: . : . .: .. :. : .: : .. KIAA07 DPDSIPSPIQVI-ENDRASRGGQVYATNT-RG----QIPPLVTTDCMIQDQGNASPRFIR 330 340 350 360 370 620 630 FLJ003 ASRMCPACHTASRKQSVMQVFWPEPQ . .: : . ::. KIAA07 CTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRCNRCKAYMCPF 380 390 400 410 420 430 >>KIAA0999 ( 1371 res) fj10213 (1371 aa) initn: 95 init1: 63 opt: 133 Z-score: 94.1 bits: 28.7 E(): 4.8 Smith-Waterman score: 154; 20.000% identity (45.490% similar) in 510 aa overlap (110-571:726-1211) 80 90 100 110 120 130 FLJ003 STFPYWSGVCREMGTAHPEAPPCALPSWEPQPHPLWGRGLEGGGERRAMQDPWLEAEPIY : : :. . . .. .:: .: KIAA09 SSIKQLQQECEQLQKMYGGQIDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSP 700 710 720 730 740 750 140 150 160 170 180 190 FLJ003 PLPIHCSQFPASLSLCDLRRAQPHSFLPAAPPYVHPASQFLRQQPHLGSHCPRERSMFQG :: : . :: :. .. : . :..:: :: ....:: : .: : .:.: KIAA09 PLQAACENQPALLT----HQLQRLRIQPSSPPPNHPNNHLFRQ-PS-NSPPPMSSAMIQP 760 770 780 790 800 200 210 220 230 240 250 FLJ003 RLCSPRDQMMRLALMEPRACVLQEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQA--- . . .:.. : :. ..:..: .. . : ....: .. . . .: KIAA09 HGAASSSQFQGLP---SRSAIFQQQPENCSSPPNVALTCLGMQQPAQSQQVTIQVQEPVD 810 820 830 840 850 860 260 270 280 290 300 FLJ003 -LQDYKGSD-DFAALAACLGPLFAEDPKKH--NLLQGFYQFVRPHHKQ---QFEEVCIQL :... :. .. . ..: .. .: ::. . :: :: . :. KIAA09 MLSNMPGTAAGSSGRGISISPSAGQMQMQHRTNLMATLSYGHRPLSKQLSADSAEAHSLN 870 880 890 900 910 920 310 320 330 340 350 360 FLJ003 TGR--GCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHL------- ..: .: : :. : .:.. . :. . : . : .. : ... KIAA09 VNRFSPANYDQAHLHPHLFSDQSRGSPSSYS-PSTGVGFSPTQALKVPPLDQFPTFPPSA 930 940 950 960 970 980 370 380 390 400 FLJ003 NQGRPH----------LSPRPPPTGDPGSHPQWGSGV--PRAGKQGQHAVS------AYL .: :: ::: :: . :. .:. :: . :. . : : KIAA09 HQQPPHYTTSALQQALLSPTPPDYTRHQQVPHILQGLLSPRHSLTGHSDIRLPPTEFAQL 990 1000 1010 1020 1030 1040 410 420 430 440 450 FLJ003 A----DARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLA--ALTTAKPEDFPLLHRFSM . :. . .: : . .. : .. :. ..: . .. . KIAA09 IKRQQQQRQQQQQQQQQQEYQELFRHMNQGDAGSLAPSLGGQSMTERQALSYQNADSYHH 1050 1060 1070 1080 1090 1100 460 470 480 490 500 510 FLJ003 FVRPHHK-QRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKT . :.: : .: :.. .. : : : : : :.: : . :. . KIAA09 HTSPQHLLQIRAQECVSQASSPTP---PHG-----YAHQPALMHSESM------EEDCSC 1110 1120 1130 1140 1150 520 530 540 550 560 570 FLJ003 QSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIA----GQQATGA .. ..: .. ..:. : .:. :.: : : . :..... :.: :.: KIAA09 EGAKDGFQDSKSSSTLTKGCHDSPLLLSTGGPGDPESLLGTVSHAQELGIHPYGHQPTAA 1160 1170 1180 1190 1200 1210 580 590 600 610 620 630 FLJ003 PGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQ KIAA09 FSKNKVPSREPVIGNCMDRSSPGQAVELPDHNGLGYPARPSVHEHHRPRALQRHHTIQNS 1220 1230 1240 1250 1260 1270 >>KIAA1860 ( 689 res) fh18358 (689 aa) initn: 80 init1: 48 opt: 128 Z-score: 93.6 bits: 27.7 E(): 5.1 Smith-Waterman score: 128; 28.571% identity (51.587% similar) in 126 aa overlap (441-558:495-610) 420 430 440 450 460 470 FLJ003 SAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTC .:. :...: ::..: : . .: KIAA18 SGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPP----SMMTR-----RNTYVC 470 480 490 500 510 480 490 500 510 520 FLJ003 TDLTGRPYPGMEPPGPQEERLA--VPPVL--THRAPQPGPSRSEKTGKTQSKISSF---- :. : :.. : : .. . :::. .: :. :: . .. .. :.: KIAA18 TERPGAERPSLLPNGKENSSGTPRVPPASPSSHSLAPPSGERS-RLARGSTIRSTFHGGQ 520 530 540 550 560 570 530 540 550 560 570 580 FLJ003 LRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVC .:.: :: :.:: . :: : : : :.: KIAA18 VRDRRAGGGGGGGVQNGPPASPTLAHEAAPLPAGRPRPTTNLFTKLTSKLTRRVTLDPSK 580 590 600 610 620 630 590 600 610 620 630 FLJ003 QGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ KIAA18 RQNSNRCVSGASLPQGSKIRSQTNLRESGDLRSQVAIYLGIKRKPPPGCSDSPGV 640 650 660 670 680 >>FLJ00201 ( 705 res) sj04110 (705 aa) initn: 130 init1: 58 opt: 127 Z-score: 92.9 bits: 27.6 E(): 5.6 Smith-Waterman score: 140; 26.119% identity (45.149% similar) in 268 aa overlap (315-575:143-388) 290 300 310 320 330 340 FLJ003 NLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQ--RAQPVLDPTGRTAPDP : : : .: : :. : : : .:. FLJ002 PGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPP--GPPGLPGPSG 120 130 140 150 160 170 350 360 370 380 390 400 FLJ003 KLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSHPQWGSGVPR-AGKQGQHAVSAY .:. . : : ::.: . .: : :: : . . : : : : :: .. . FLJ002 -ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGP 180 190 200 210 220 410 420 430 440 450 460 FLJ003 LADARRA-LGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRP . : ::. : . : .: . : .. : . . .. :. : . .. : FLJ002 PGLPGPAGLGKPGLDGLPGA-PGDKGESGPPGVPGPRGEPGAVGPKGPPGVD--GVGVPG 230 240 250 260 270 280 470 480 490 500 510 FLJ003 HHKQRFSQTCTDLTGRPYPGME-PPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKI : . :. :: . ::: . :. ::: : . . . FLJ002 AAGLPGPQGPSGAKGE--PGTRGPPG------LIGPTGYGMPGLPGP----KGDRGPAGV 290 300 310 320 330 520 530 540 550 560 570 FLJ003 SSFLRQRPAGTVGAGGE--DAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLS ..: .: : : :: . ::. .::: :... : : : : .. ..:::: FLJ002 PGLLGDR--GEPGEDGEPGEQGPQGLGGPPGLPGSA--GLPGRRGPPGPKGEAGPGGPPG 340 350 360 370 380 390 580 590 600 610 620 630 FLJ003 AGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEP FLJ002 VPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKG 400 410 420 430 440 450 638 residues in 1 query sequences 2210356 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 11:01:52 2009 done: Fri Feb 27 11:01:53 2009 Total Scan time: 0.640 Total Display time: 0.170 Function used was FASTA [version 34.26.5 April 26, 2007]