# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh06047.fasta.huge -Q ../query/FLJ00310.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00310, 291 aa vs ./tmplib.10216 library 2210703 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 9.1321+/-0.00653; mu= -11.5608+/- 0.433 mean_var=300.3134+/-72.721, 0's: 0 Z-trim: 9 B-trim: 48 in 1/39 Lambda= 0.074009 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 36, opt: 24, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA2015 ( 996 res) fk09763 ( 996) 616 79.3 9.9e-16 KIAA1074 ( 1715 res) hj06637 (1715) 417 58.3 3.6e-09 KIAA0565 ( 641 res) hh01904(revised) ( 641) 283 43.5 3.7e-05 KIAA1641 ( 718 res) fj10609s1 ( 718) 260 41.1 0.00022 KIAA1081 ( 1003 res) bg00262 (1003) 169 31.5 0.23 KIAA1565 ( 1313 res) bf00184 (1313) 166 31.3 0.35 KIAA1212 ( 802 res) fh00638s1 ( 802) 160 30.5 0.39 KIAA1276 ( 1068 res) fh00139s1 (1068) 159 30.5 0.51 KIAA0178 ( 1233 res) ha02501s1 (1233) 157 30.3 0.65 KIAA1275 ( 1140 res) hk10413 (1140) 153 29.9 0.83 KIAA1334 ( 989 res) fh15842 ( 989) 151 29.6 0.87 KIAA0619 ( 1428 res) hg04117 (1428) 153 30.0 0.96 KIAA1509 ( 1365 res) fh14721 (1365) 151 29.8 1.1 KIAA0581 ( 1218 res) pf10976 (1218) 149 29.5 1.2 KIAA0378 ( 970 res) hh00502s1 ( 970) 144 28.8 1.4 KIAA1000 ( 1956 res) hk09604y2 (1956) 147 29.5 1.9 KIAA1971 ( 830 res) fk08985 ( 830) 137 28.0 2.2 KIAA0216 ( 2067 res) hf00331s1 (2067) 143 29.1 2.6 FLJ00316 ( 649 res) sh06964 ( 649) 127 26.8 3.9 FLJ00150 ( 1793 res) sh05613 (1793) 136 28.3 3.9 KIAA0866 ( 1984 res) hk00546s1 (1984) 136 28.3 4.2 KIAA1590 ( 1393 res) fj09048y1 (1393) 132 27.7 4.5 KIAA1167 ( 834 res) hj01786(revised) ( 834) 127 27.0 4.6 KIAA0845 ( 1034 res) hk05234s1 (1034) 127 27.1 5.3 KIAA0531 ( 999 res) hg03072 ( 999) 126 26.9 5.6 KIAA0594 ( 1120 res) hj02896s1 (1120) 127 27.1 5.6 KIAA1524 ( 884 res) fj00637(revised) ( 884) 124 26.7 5.9 KIAA1601 ( 690 res) fj10228 ( 690) 120 26.1 6.8 KIAA1512 ( 2010 res) fg04660y1 (2010) 129 27.6 7.2 FLJ00279 ( 563 res) sh01691 ( 563) 117 25.7 7.4 KIAA0989 ( 859 res) hk05377 ( 859) 120 26.2 7.8 KIAA2012 ( 555 res) ah04096 ( 555) 115 25.5 8.4 KIAA0139 ( 1388 res) ha04032 (1388) 123 26.8 8.7 KIAA1222 ( 742 res) fh03567 ( 742) 117 25.8 8.9 KIAA1937 ( 704 res) fk04595 ( 704) 116 25.7 9.2 KIAA1801 ( 1227 res) fj21373 (1227) 121 26.5 9.3 KIAA0389 ( 1296 res) hj00061 (1296) 121 26.5 9.6 KIAA0612 ( 1810 res) hg00654s1 (1810) 124 27.0 9.6 KIAA0980 ( 1406 res) hj07083 (1406) 121 26.6 10 KIAA0635 ( 864 res) hj03253 ( 864) 116 25.8 11 KIAA1793 ( 1270 res) fj07087 (1270) 119 26.3 11 KIAA1662 ( 1653 res) fj03879s1 (1653) 121 26.6 11 KIAA1716 ( 804 res) hj06603 ( 804) 114 25.6 12 KIAA1230 ( 932 res) fh06860s1 ( 932) 115 25.7 12 KIAA0445 ( 1919 res) hg00102s1 (1919) 121 26.7 13 KIAA1826 ( 380 res) fj12317 ( 380) 106 24.3 13 KIAA1166 ( 165 res) hk01743 ( 165) 98 23.1 13 KIAA0202 ( 508 res) ha02944 ( 508) 108 24.7 13 KIAA1735 ( 493 res) ph00512 ( 493) 107 24.6 14 KIAA1288 ( 1245 res) hh13551(revised) (1245) 114 25.8 16 >>KIAA2015 ( 996 res) fk09763 (996 aa) initn: 806 init1: 569 opt: 616 Z-score: 375.8 bits: 79.3 E(): 9.9e-16 Smith-Waterman score: 939; 48.619% identity (68.232% similar) in 362 aa overlap (6-286:502-862) 10 20 30 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYEN ..:.... . :: :.:..:::::.:. : KIAA20 KNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPN 480 490 500 510 520 530 40 50 60 70 80 90 FLJ003 AEDKVNNSTGKWSCVEERICHLQHENPCLEQQLDDVHQKEDHKEIVTNIQRGFIESGKKD .: : ..: :: . .:::: . . :: ::.::.:.... :.:::: ::.: .:.::.: KIAA20 GEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKED 540 550 560 570 580 590 100 110 120 130 140 150 FLJ003 LMLEEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLESPLEGIS : :::.::.::.: ..:::.:.: :.::::: :.::..:.: .: :: ... :::::: : KIAA20 L-LEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGTS 600 610 620 630 640 650 160 170 FLJ003 HYHINLDETQVPKKKLFQVESQ-------------------------------------- : ::::.:: . :::::::: : KIAA20 HCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATG 660 670 680 690 700 710 180 190 FLJ003 -------------------------------------------FDDLMVEKEAVSSKCVN :.::..:::::::.::: KIAA20 YKKCLEMTINMLNAFANEDFNCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVN 720 730 740 750 760 770 200 210 220 230 240 250 FLJ003 LAKENQVFQQKLLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSEL :::.:.:..:.::::..::..:::::.::::::::.::::::::..::::.::::::::: KIAA20 LAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSEL 780 790 800 810 820 830 260 270 280 290 FLJ003 DERAMQAVEKLEEIHLQEQAQYKKQLEQLNKDIIQLH ::::.: .:::::::::.::.:.::::::::: KIAA20 DERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEE 840 850 860 870 880 890 KIAA20 VTTELEEFKEVFAAAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPEP 900 910 920 930 940 950 >>KIAA1074 ( 1715 res) hj06637 (1715 aa) initn: 854 init1: 314 opt: 417 Z-score: 258.1 bits: 58.3 E(): 3.6e-09 Smith-Waterman score: 643; 36.279% identity (53.953% similar) in 430 aa overlap (6-286:1093-1522) 10 20 30 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYEN ..:..:.. .:::::: :.:::.. :.: KIAA10 NNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQN 1070 1080 1090 1100 1110 1120 40 50 60 70 80 FLJ003 AEDKVNNSTGKWSCVEERICHLQHENPCLEQQLDDVHQKEDHKE-IVTNIQRGF------ . :::. :: ::::. .:: :: :.:::::.:.: :.:: : ::: : KIAA10 EQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQK 1130 1140 1150 1160 1170 1180 90 100 110 120 130 140 FLJ003 --IESGKKDLMLEEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTM :: :..:.:::.::.:..::.:::: .::: ::::: ::::::::: ::.::: .: KIAA10 LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSM 1190 1200 1210 1220 1230 1240 150 160 170 FLJ003 LESPLEGISHYHINL-DETQVPKKKLFQVE------------------------------ :. :: :.:.::: :::: :::: :.. KIAA10 SEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKD 1250 1260 1270 1280 1290 1300 FLJ003 ------------------------------------------------------------ KIAA10 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1310 1320 1330 1340 1350 1360 180 FLJ003 ---------------------------------SQF-------------DDLMVEKEAVS ::: ::: .: :... KIAA10 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAG 1370 1380 1390 1400 1410 1420 190 200 210 220 230 240 FLJ003 SKCVNLAKENQVFQQKLLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQE :::..: .::..:..::::: ::..::::...:: ::.:..::..:.: .::::..... KIAA10 SKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQ 1430 1440 1450 1460 1470 1480 250 260 270 280 290 FLJ003 YKSELDERAMQAV-EKLEEIHL--QEQAQYKKQLEQLNKDIIQLH ::.:..::: : . :::.:..: : :: ...:::. .. KIAA10 YKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESEL 1490 1500 1510 1520 1530 1540 KIAA10 SKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSL 1550 1560 1570 1580 1590 1600 >>KIAA0565 ( 641 res) hh01904(revised) (641 aa) initn: 498 init1: 202 opt: 283 Z-score: 185.9 bits: 43.5 E(): 3.7e-05 Smith-Waterman score: 455; 37.324% identity (59.859% similar) in 284 aa overlap (18-286:310-542) 10 20 30 40 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEDKVNNSTGKW :::::: : :: ..::. ..:... .: KIAA05 ESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQ 280 290 300 310 320 330 50 60 70 80 90 FLJ003 SCVEERICHLQHENPCLEQQLDDVHQKEDHKEIVTN-IQRGF--------IESGKKDLML ::::. .:: :: :.:::::.:.: . .: ... :: : :: :. : : KIAA05 ESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSL 340 350 360 370 380 390 100 110 120 130 140 150 FLJ003 EEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYH .::::.::.: .:::: . : :.::: : . KIAA05 QEKNKELMDEYNHLKERMDQCEKEKAGR-------------------------------K 400 410 420 160 170 180 190 200 210 FLJ003 INLDETQVPKKKLFQVESQFDDLMVEKEAVSSKCVNLAKENQVFQ--QKLLSMKKVQQEC :.: :.: :.: :.:..: ::.:.: : :.::: .:..: KIAA05 IDLTEAQ--------------------ETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQC 430 440 450 460 220 230 240 250 260 270 FLJ003 EKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE-KLEE--IHLQEQ : :...::.:..:..:::..:: .:.: .: . .: ..::: . .: ::.: . ::.: KIAA05 ETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQ 470 480 490 500 510 520 280 290 FLJ003 AQYK-KQLEQLNKDIIQLH : . .:: :: .: KIAA05 AAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEV 530 540 550 560 570 580 >>KIAA1641 ( 718 res) fj10609s1 (718 aa) initn: 253 init1: 165 opt: 260 Z-score: 172.0 bits: 41.1 E(): 0.00022 Smith-Waterman score: 345; 38.043% identity (67.935% similar) in 184 aa overlap (6-177:528-705) 10 20 30 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYEN ..:.. :.. ..:.: :.:.:....::.. KIAA16 HVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 500 510 520 530 540 550 40 50 60 70 80 FLJ003 AEDKVNNSTGKWSCVE--ERICHLQHENPCLEQQLDDVHQKEDHKE-IVTNIQRGF---- . . ... :.: ::.:.:...: :.:::::...: :..: . ::: KIAA16 GYNTMEK------CIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV 560 570 580 590 600 610 90 100 110 120 130 140 FLJ003 ----IESGKKDLMLEEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKL : :. :.::: :: :.:: : ::. :::.::::: :.::::::. : :.: KIAA16 QNLQAECRKHRLLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKG 620 630 640 650 660 670 150 160 170 180 190 200 FLJ003 TMLESPLEGISHYHINLDE-TQVPKKKLFQVESQFDDLMVEKEAVSSKCVNLAKENQVFQ . .. :.. :.. :.. : .::: :..:: KIAA16 SATKALLDASSRHCTYLENGMQDSRKKLDQMRSQVCMQLCTPTTVNL 680 690 700 710 210 220 230 240 250 260 FLJ003 QKLLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE >>KIAA1081 ( 1003 res) bg00262 (1003 aa) initn: 148 init1: 68 opt: 169 Z-score: 117.8 bits: 31.5 E(): 0.23 Smith-Waterman score: 171; 20.727% identity (54.182% similar) in 275 aa overlap (19-290:521-783) 10 20 30 40 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEDKVNNSTGKWS :.. .::..: : . .... . KIAA10 ESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLD 500 510 520 530 540 550 50 60 70 80 90 100 FLJ003 CVEERICHLQHENPCLEQQL-DDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMN :... ::.. :..:: : .: . :: : ..: .. ::: . KIAA10 VKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 560 570 580 590 600 610 110 120 130 140 150 160 FLJ003 ECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDE--TQ ..:::. . :::: :.. . ... : .:...:.. : ..: : .. KIAA10 TIERLKEQRDRDEREKQEEI---DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 620 630 640 650 660 170 180 190 200 210 220 FLJ003 VPKKKLFQVESQFDDLMVEKEAVSSKCVNLAKENQVFQQKLLSMKKVQQECEKLEEDKKM . .. : . .:.. : . : . .:... .. . .. : . . ..... KIAA10 LASSGL-KKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQH---- 670 680 690 700 710 720 230 240 250 260 270 280 FLJ003 LEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAQYKKQLEQLNK ::.:: : . ....:...: : .:.... . .:. :.. . : : : :: KIAA10 LEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQ----NK 730 740 750 760 770 290 FLJ003 DIIQLH . .: KIAA10 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 780 790 800 810 820 830 >>KIAA1565 ( 1313 res) bf00184 (1313 aa) initn: 131 init1: 56 opt: 166 Z-score: 114.6 bits: 31.3 E(): 0.35 Smith-Waterman score: 175; 24.415% identity (59.866% similar) in 299 aa overlap (1-281:861-1135) 10 20 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQ---QQIK : :. :. . .: .....:. :. KIAA15 QRELQEGRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLNGSQEEMQKTETVKQENA 840 850 860 870 880 890 30 40 50 60 70 80 FLJ003 EMKEMYENAEDKVNNSTGKWSCVEERICHLQHENPCLEQQLDDVHQKEDHKEIVTNIQRG ...: :: . .... : . .. . .:...: ...:....:. :.. . .. KIAA15 AVQKMVENLKKQISELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLT--EMLCQKEK- 900 910 920 930 940 90 100 110 120 130 140 FLJ003 FIESGKKDLMLEEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLT-- : :.. :::.... .: ::: : :: :.. ..: .:. : .. .: : KIAA15 --EPGNS--ALEEREQEKFN----LKEEL---ERCKVQSSTLVSSLEAELSE-VKIQTHI 950 960 970 980 990 150 160 170 180 190 FLJ003 ------MLESPLEGISHYHINLDETQVPKKKLFQVESQFDDLMVEKEAVS---SKCVNLA .:.. :: ... : : .. ..:. .: : . :. ::::.: ..::. KIAA15 VQQENHLLKDELEKMKQLHRCPDLSDF-QQKISSVLSYNEKLLKEKEALSEELNSCVDKL 1000 1010 1020 1030 1040 1050 200 210 220 230 240 250 FLJ003 KENQVFQQKLLSMKKVQQECEKLEED-KKML---EEEILNLKTHMENSMVELSKLQEYKS ......... .::. :. :. . :..: .:.. ::. ..: ...:.. :: KIAA15 AKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRM---KS 1060 1070 1080 1090 1100 1110 260 270 280 290 FLJ003 ELDERAMQAVEKLEEIHLQEQAQYKKQLEQLNKDIIQLH .: :. : :: : :: . .:::. KIAA15 DL--RVTQQ-EK--EALKQEVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSWDKLD 1120 1130 1140 1150 1160 >>KIAA1212 ( 802 res) fh00638s1 (802 aa) initn: 68 init1: 68 opt: 160 Z-score: 113.8 bits: 30.5 E(): 0.39 Smith-Waterman score: 160; 21.491% identity (61.404% similar) in 228 aa overlap (66-282:120-339) 40 50 60 70 80 90 FLJ003 AEDKVNNSTGKWSCVEERICHLQHENPCLEQQLDDVHQKE--DHKEIVTNIQRGFIESGK ..:. .:... ... ... ..: ..:.. KIAA12 QQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLIS--KHGTLKSAH 90 100 110 120 130 140 100 110 120 130 140 FLJ003 KDLM-----LEEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLE :.: ::.. ..:... .: :.: .. . . :.... . .. .: ::: . KIAA12 KNLEVEHRDLEDRYNQLLKQKGQL-EDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 150 160 170 180 190 200 150 160 170 180 190 200 FLJ003 SPLEGISHYHINLDETQVPKKKLFQVESQFDDLMVEKEAVSSKCVNLAKENQVFQQKLLS . :. : : ::.: . ...: ... .:. . .. ..: .. .:: .. KIAA12 DRLN--HTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAE---FSKLKEQYQQLDIT 210 220 230 240 250 260 210 220 230 240 250 260 FLJ003 MKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVE----LSKLQEYKSELDERAMQAVEK :....:: : . : :::: .: .... :.. : . .: :. . . : ..: KIAA12 STKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDK 270 280 290 300 310 320 270 280 290 FLJ003 LEEIHLQEQAQYKKQLEQLNKDIIQLH :.:.. :.. .: ..: KIAA12 LNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTP 330 340 350 360 370 380 >>KIAA1276 ( 1068 res) fh00139s1 (1068 aa) initn: 120 init1: 58 opt: 159 Z-score: 111.7 bits: 30.5 E(): 0.51 Smith-Waterman score: 160; 25.000% identity (56.507% similar) in 292 aa overlap (21-290:402-677) 10 20 30 40 50 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEDKVNNSTGKWSCV ... . . ::..::. :....: KIAA12 EAGNLHPQQDQSCLKECPCMKGGTDMQTKKEASAETEYMKQQYEEDLRKIKHQT------ 380 390 400 410 420 60 70 80 90 100 FLJ003 EERICHLQHENPCLEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLM------LEEKNKK ::. ::. . : ..:.:. .: : . .. :. .:. .: :. ::: :: KIAA12 EEEKKHLKDQ---LVKRLEDLVKK--HTVEIKSV-RSSVEAERKKLQREVEAQLEEVRKK 430 440 450 460 470 110 120 130 140 150 160 FLJ003 LMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLT-MLESPLEGISHYHINLDE .: .:.: . . . .. : .:.. .. . : ::: : ... : .. : KIAA12 SEKEIKQLEEEKAALNVKLQNSLLEVLRLEEFIQQNKTRPTGAEESPQE-LGRQHCSILE 480 490 500 510 520 530 170 180 190 200 210 FLJ003 TQVPKKKLFQVES---QFDDLMVEKEAVSS----KCVNLAKENQVFQQKLLSM-KKVQQE :: : :: .. ...: .. .:..:: . : ::.. : : :. :. .. KIAA12 TQDPCLKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSK 540 550 560 570 580 590 220 230 240 250 260 FLJ003 CEKLEED----KKMLEEEILNLKTHMENSMVELSK-LQEYK--SELDERAMQAVEKLEEI ..:::: : :. .. ... .:. . . :: : :.:... .: ..:.: KIAA12 IQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQALKQLSDLEREKLQ--HELQET 600 610 620 630 640 650 270 280 290 FLJ003 HLQEQAQYKKQLEQLNKDIIQLH :..:. : ::: .. ... KIAA12 TQQNHAM-KAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQAL 660 670 680 690 700 710 >>KIAA0178 ( 1233 res) ha02501s1 (1233 aa) initn: 126 init1: 60 opt: 157 Z-score: 109.8 bits: 30.3 E(): 0.65 Smith-Waterman score: 164; 20.147% identity (58.242% similar) in 273 aa overlap (19-290:228-480) 10 20 30 40 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEDKVNNSTGKWS : ... .:..... . . ..... . . KIAA01 EAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMD 200 210 220 230 240 250 50 60 70 80 90 100 FLJ003 CVEERICHLQHENPCLEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNE ::... . ..: . .. ...... .:. : .: ..:.. .: ::: KIAA01 KVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKEN--TSHKIKKLEAA 260 270 280 290 300 310 110 120 130 140 150 160 FLJ003 CDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDETQVPK :... .:...:.. . .:..: . : .: .: .:.: KIAA01 KKSLQNAQKHYKKRKGD----MDELEKEMLSVEKARQEFEERME---------EESQSQG 320 330 340 350 360 170 180 190 200 210 220 FLJ003 KKLFQVESQFDDLMVEKEAVSSKCVNLAKENQVFQQKLLSMKKVQQECEKLEEDKKMLEE . : :.: :: .:.. ..::.: . :.. .:..:. ::: ::. : KIAA01 RDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRD----QKADQDRLDLEERKKVETE 370 380 390 400 410 230 240 250 260 270 280 FLJ003 EILNLKTH-MENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAQYKKQLEQLNKDI .. : . .:... .. ::.:: . ...... .::: .: . :......::.. KIAA01 AKIKQKLREIEENQKRIEKLEEYITT-SKQSLEEQKKLEGELTEEVEMAKRRIDEINKEL 420 430 440 450 460 470 290 FLJ003 IQLH :. KIAA01 NQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKV 480 490 500 510 520 530 >>KIAA1275 ( 1140 res) hk10413 (1140 aa) initn: 71 init1: 71 opt: 153 Z-score: 107.9 bits: 29.9 E(): 0.83 Smith-Waterman score: 187; 20.641% identity (62.989% similar) in 281 aa overlap (3-266:256-534) 10 20 30 FLJ003 EKRYSQKKVIGFRNSPNDLSQTQQQIKEMKEM : . :..:. . ..: .:...... .: KIAA12 LEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEE 230 240 250 260 270 280 40 50 60 70 80 90 FLJ003 YENAEDKVNNSTGKWSCVEERICHLQHENPCLEQQLDDVHQKEDH-KEIVTNIQRGFIES .. .::. .. : . .. .:... .: . ... . :.. .:. ..:. : KIAA12 LQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEE--EH 290 300 310 320 330 340 100 110 120 130 140 150 FLJ003 GKKDLMLE-EKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLESP .:.: :: :: .: :.: ..:.:.. . . : .. . ... .. . : :..: ...: KIAA12 HSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSR 350 360 370 380 390 400 160 170 180 190 200 FLJ003 LEGISHYHINLDETQVPKKKLFQVESQFDDLMVEK-----EAVSS---KCVNLAKENQVF .. . . :..... : . ..: ..:.. : ... : .: :. .: KIAA12 VKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVE 410 420 430 440 450 460 210 220 230 240 250 FLJ003 QQKLLSM-KKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSELD------ : :.... .:. .: .:: . :. .::.. :: . .. . .:.. .: .:::. KIAA12 QGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLL 470 480 490 500 510 520 260 270 280 290 FLJ003 ERAMQAVEKLEEIHLQEQAQYKKQLEQLNKDIIQLH .. ....:..: KIAA12 KKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKT 530 540 550 560 570 580 291 residues in 1 query sequences 2210703 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:51:27 2009 done: Fri Feb 27 10:51:28 2009 Total Scan time: 0.430 Total Display time: 0.090 Function used was FASTA [version 34.26.5 April 26, 2007]