# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh07586.fasta.huge -Q ../query/FLJ00320.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00320, 267 aa vs ./tmplib.10216 library 2210727 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 6.1264+/-0.00532; mu= 10.2391+/- 0.358 mean_var=165.3520+/-37.297, 0's: 0 Z-trim: 7 B-trim: 24 in 1/39 Lambda= 0.099740 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 36, opt: 24, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1962 ( 746 res) hm00158 ( 746) 356 62.4 8.3e-11 KIAA0426 ( 613 res) hh01274 ( 613) 343 60.4 2.7e-10 FLJ00187 ( 563 res) sj02149 ( 563) 327 58.0 1.3e-09 KIAA1015 ( 841 res) hk03609(revised) ( 841) 327 58.3 1.6e-09 KIAA0557 ( 493 res) hh01334 ( 493) 319 56.8 2.6e-09 KIAA0287 ( 1523 res) fg06332 (1523) 217 42.8 0.00013 FLJ00280 ( 440 res) sh01728 ( 440) 127 29.1 0.5 KIAA1139 ( 1124 res) hk00330 (1124) 124 29.2 1.2 KIAA1973 ( 1176 res) pf00154 (1176) 115 27.9 3 KIAA1211 ( 803 res) fh00041 ( 803) 107 26.6 5.3 KIAA0775 ( 639 res) hk05255 ( 639) 104 26.0 6.2 KIAA0620 ( 1985 res) hg04174 (1985) 109 27.4 7.5 FLJ00311 ( 249 res) sh06450 ( 249) 96 24.3 7.7 FLJ00153 ( 497 res) sh06127 ( 497) 98 25.0 9.7 KIAA1075 ( 1505 res) hj06716s1 (1505) 103 26.3 12 KIAA0293 ( 1505 res) hg03205 (1505) 103 26.3 12 KIAA0333 ( 1223 res) pf04993 (1223) 101 25.9 12 KIAA0141 ( 536 res) ha03721 ( 536) 95 24.6 14 FLJ00221 ( 298 res) sj06160 ( 298) 91 23.7 14 FLJ00328 ( 238 res) sj02853 ( 238) 89 23.3 15 KIAA1299 ( 730 res) fg04370 ( 730) 95 24.8 17 KIAA1662 ( 1653 res) fj03879s1 (1653) 100 26.0 17 FLJ00174 ( 628 res) sj00729 ( 628) 94 24.6 17 KIAA0755 ( 1093 res) hk04532 (1093) 96 25.2 19 KIAA1187 ( 813 res) fk03027 ( 813) 93 24.6 22 KIAA1355 ( 1189 res) fj01564 (1189) 95 25.1 22 KIAA0992 ( 772 res) hk07554 ( 772) 92 24.4 23 KIAA0867 ( 568 res) hk06783 ( 568) 90 23.9 23 KIAA1532 ( 601 res) fg04455(revised) ( 601) 90 24.0 24 FLJ00277 ( 357 res) sh01540 ( 357) 86 23.1 26 KIAA0754 ( 1174 res) hh06485 (1174) 92 24.6 30 KIAA1227 ( 1069 res) fh04710 (1069) 90 24.3 34 KIAA1783 ( 1560 res) fg01285 (1560) 92 24.8 35 KIAA1856 ( 1134 res) fh03203 (1134) 90 24.3 35 KIAA0437 ( 1605 res) hj00203s1 (1605) 92 24.8 36 KIAA1960 ( 871 res) hk03842 ( 871) 88 23.9 37 KIAA1723 ( 1554 res) pf00881 (1554) 91 24.6 39 KIAA0367 ( 820 res) hh00141s1 ( 820) 87 23.7 39 KIAA1836 ( 718 res) fh12206(revised) ( 718) 86 23.5 40 KIAA0487 ( 234 res) fk08362 ( 234) 79 21.8 40 KIAA0540 ( 2041 res) pg00116 (2041) 92 24.9 41 KIAA1862 ( 1070 res) aj00563 (1070) 88 24.0 42 KIAA1085 ( 584 res) hj07690 ( 584) 84 23.1 43 FLJ00007 ( 701 res) as00007 ( 701) 85 23.3 43 KIAA0460 ( 1452 res) bj00064 (1452) 89 24.3 45 KIAA0468 ( 410 res) hg01596 ( 410) 81 22.5 46 KIAA0945 ( 797 res) hj04760 ( 797) 85 23.4 47 KIAA1066 ( 1346 res) ah03682 (1346) 88 24.1 48 KIAA1514 ( 1598 res) fh00815(revised) (1598) 89 24.4 48 KIAA1681 ( 1236 res) fh23697 (1236) 87 23.9 50 >>KIAA1962 ( 746 res) hm00158 (746 aa) initn: 339 init1: 339 opt: 356 Z-score: 287.4 bits: 62.4 E(): 8.3e-11 Smith-Waterman score: 356; 45.588% identity (70.588% similar) in 136 aa overlap (71-203:6-138) 50 60 70 80 90 FLJ003 TGHLVIPGTSPLEPPCPWLDSHIFQCRFGKMLPLEKAFASPRSSPAPPDLPTPGSAAG-- ..::.: : :: : : . . KIAA19 DTMQAVVPLNKMTA---ISPEPQTLASTEQNEVPR 10 20 30 100 110 120 130 140 150 FLJ003 -VQQEEPETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQ : . : :.: . . :: : : ::: : :.:.:::...:..: ::: ::: :. ..::: KIAA19 VVTSGEQEAILRGNAADAESFRQRFRWFCYSEVAGPRKALSQLWELCNQWLRPDIHTKEQ 40 50 60 70 80 90 160 170 180 190 200 210 FLJ003 MLELLVLEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSI .:::::.:::: ::: ..: :: .:.::: .....:.: :...::: KIAA19 ILELLVFEQFLTILPGEIRIWVKSQHPESSEEVVTLIEDLTQMLEEKDPVSQDSTVSQEE 100 110 120 130 140 150 220 230 240 250 260 FLJ003 LSDGVYERHMDPLLLPGELASPSQALGAGEIPAPSETRECPASLAASAGP KIAA19 NSKEDKMVTVCPNTESCESITLKDVAVNFSRGEWKKLEPFQKELYKEVLLENLRNLEFLD 160 170 180 190 200 210 >>KIAA0426 ( 613 res) hh01274 (613 aa) initn: 341 init1: 341 opt: 343 Z-score: 278.2 bits: 60.4 E(): 2.7e-10 Smith-Waterman score: 343; 48.544% identity (79.612% similar) in 103 aa overlap (116-218:52-154) 90 100 110 120 130 140 FLJ003 APPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFREFVYQEAAGPHQTLARLHELCR : : ::.: :::..::...:.::.:::. KIAA04 QDEPLEVKIEEEKYTTRQDWDLRKNNTHSREVFRQYFRQFCYQETSGPREALSRLRELCH 30 40 50 60 70 80 150 160 170 180 190 200 FLJ003 QWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPG ::: ::...:::.:::::::::: :::.... :: :.::: .......: : :.::: KIAA04 QWLRPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPG 90 100 110 120 130 140 210 220 230 240 250 260 FLJ003 MLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQALGAGEIPAPSETRECPASLAASA .. .: . .. KIAA04 EQVSVHTGEQEMFLQETVRLRKEGEPSMSLQSMKAQPKYESPELESQQEQVLDVETGNEY 150 160 170 180 190 200 >>FLJ00187 ( 563 res) sj02149 (563 aa) initn: 292 init1: 257 opt: 327 Z-score: 266.2 bits: 58.0 E(): 1.3e-09 Smith-Waterman score: 327; 36.875% identity (65.625% similar) in 160 aa overlap (106-260:43-198) 80 90 100 110 120 130 FLJ003 KAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFREFVYQEAAGPHQ :. . : : :. : :::.: ::.. ::.. FLJ001 SPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFRRFCYQNTFGPRE 20 30 40 50 60 70 140 150 160 170 180 190 FLJ003 TLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCKKAASLVE .:.::.:::.::: :: .:::.::::::::::.::: ... :. :.: ..:..:.: FLJ001 ALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLE 80 90 100 110 120 130 200 210 220 230 240 250 FLJ003 GLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGEL-----ASPSQALGAGEIPA : :. :. . . . . .:. :. .::. . . :. :. ... : FLJ001 DLE--LDLSGQQVPGQVHGPEMLARGMVP--LDPVQESSSFDLHHEATQSHFKHSSRKPR 140 150 160 170 180 260 FLJ003 PSETRECPASLAASAGP ..: ::. FLJ001 LLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNLAR 190 200 210 220 230 240 >>KIAA1015 ( 841 res) hk03609(revised) (841 aa) initn: 305 init1: 305 opt: 327 Z-score: 264.2 bits: 58.3 E(): 1.6e-09 Smith-Waterman score: 327; 46.667% identity (77.143% similar) in 105 aa overlap (99-203:32-136) 70 80 90 100 110 120 FLJ003 GKMLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFREFVYQ :..:. . : .: .: :::.: :. KIAA10 GMIMTESREVIDLDPPAETSQEQEDLFIVKVEEEDCTWMQEYNPPTFETFYQRFRHFQYH 10 20 30 40 50 60 130 140 150 160 170 180 FLJ003 EAAGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCK ::.::...:..:. :: .:: :: ..:::.:::::::::: :::.. .::: ..::: . KIAA10 EASGPREALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTILPEEFQPWVREHHPESGE 70 80 90 100 110 120 190 200 210 220 230 240 FLJ003 KAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQALGAGEI .:....:.. ::: KIAA10 EAVAVIENIQRELEERRQQIVACPDVLPRKMATPGAVQESCSPHPLTVDTQPEQAPQKPR 130 140 150 160 170 180 >>KIAA0557 ( 493 res) hh01334 (493 aa) initn: 348 init1: 297 opt: 319 Z-score: 260.6 bits: 56.8 E(): 2.6e-09 Smith-Waterman score: 319; 53.608% identity (75.258% similar) in 97 aa overlap (101-197:47-141) 80 90 100 110 120 130 FLJ003 MLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFREFVYQEA .::: .. . :. : .: :: : :::. KIAA05 VPGLQPLPTLEQDLEQEEILIVKVEEDFCLEEEP-SVETEDPSPETFRQL-FRLFCYQEV 20 30 40 50 60 70 140 150 160 170 180 190 FLJ003 AGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYPESCKKA :::...:.:: ::: .:: :: :.:::.:::::::::: .:: ... : : ::: ..: KIAA05 AGPREALSRLWELCCRWLRPELRTKEQILELLVLEQFLTVLPGEIQARVREQQPESGEEA 80 90 100 110 120 130 200 210 220 230 240 250 FLJ003 ASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQALGAGEIPA . ::::: KIAA05 VVLVEGLQRKPRKHRQRGSELLSDDEVPLGIGGQFLKHQAEAQPEDLSLEEEARFSSQQP 140 150 160 170 180 190 >>KIAA0287 ( 1523 res) fg06332 (1523 aa) initn: 201 init1: 201 opt: 217 Z-score: 175.9 bits: 42.8 E(): 0.00013 Smith-Waterman score: 217; 48.214% identity (87.500% similar) in 56 aa overlap (147-202:7-62) 120 130 140 150 160 170 FLJ003 FSRLRFREFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVR :..::.:.::...:::::::.: :.:.:.. KIAA02 VQTLGGWVQPETRTKEEIIELLVLEQYLTIIPEKLK 10 20 30 180 190 200 210 220 230 FLJ003 PWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGEL ::: :. ::.:.: ..:.:. .. . KIAA02 PWVRAKKPENCEKLVTLLENYKEMYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSGD 40 50 60 70 80 90 >>FLJ00280 ( 440 res) sh01728 (440 aa) initn: 382 init1: 99 opt: 127 Z-score: 111.8 bits: 29.1 E(): 0.5 Smith-Waterman score: 127; 37.705% identity (54.098% similar) in 61 aa overlap (38-95:39-99) 10 20 30 40 50 60 FLJ003 FSGSWGGCALALCKAIALSVSSAGLWVLAPPEPTGHLVIPGTSPLEPPCPWL-DSHIFQC : : : .:: ::: : :. . FLJ002 GCHADGTRTRTLPPPGILRTPGTLPCPGTLPPPRTHSYLPGHSPLLGHTPTSRDTPPSRN 10 20 30 40 50 60 70 80 90 100 110 120 FLJ003 RFGK--MLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFRE . ::: ... :::. :.: :::::. FLJ002 TLPPPWMLPSPRTLPSPRTLPSPRTLPTPGTHFYLPGHSPLLGHTSPSWDTLPPPGTHFP 70 80 90 100 110 120 130 140 150 160 170 180 FLJ003 FVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQYP FLJ002 LQGHTSPSWDILPTPGMLPSPRTLPAPRTHSYFLGRSPFPGHSPLLGHYPLPGHTPRYRD 130 140 150 160 170 180 >>KIAA1139 ( 1124 res) hk00330 (1124 aa) initn: 107 init1: 63 opt: 124 Z-score: 105.0 bits: 29.2 E(): 1.2 Smith-Waterman score: 128; 25.203% identity (45.528% similar) in 246 aa overlap (37-263:792-1023) 10 20 30 40 50 60 FLJ003 LFSGSWGGCALALCKAIALSVSSAGLWVLAPPEPTGHLVIPGTSPLEPPCPWLDSHIFQC :: : . : :: ::: : ::. KIAA11 RTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSP-EPP-P-LDGSPGP- 770 780 790 800 810 70 80 90 100 110 FLJ003 RFGKMLPLEKAFASPRSSPAPPDLPTP-GSAAGVQQEEPETIPERTPAD-------LEFS . : : ..... : . :: :.: : :. ...::: :: :: . : :. KIAA11 KEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPG--PEGTPPSRGSSGEGLPFA 820 830 840 850 860 870 120 130 140 150 160 FLJ003 R---LRFREFVYQEAAGPHQTLA------RLHELCRQWLMPEARSKEQMLELLVLEQFLG . : ... . :..: . : : :. : .: . :. . KIAA11 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVAS 880 890 900 910 920 930 170 180 190 200 210 220 FLJ003 ILPDKVRPWVVAQYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDP : . : . . : :.:: . . : :.. . .: . : .. : : KIAA11 ATPGPAAP-LPSPTPGESPPASSLPQPEPSSL--PAQGVPTPLAPSPAMQPPV-----PP 940 950 960 970 980 230 240 250 260 FLJ003 LLLPG-ELASPSQALGAGEIPA-PSETRECPASLAASAGP :: : .. :. : : :: :. . :.. .: KIAA11 CPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGP 990 1000 1010 1020 1030 1040 KIAA11 RPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDD 1050 1060 1070 1080 1090 1100 >>KIAA1973 ( 1176 res) pf00154 (1176 aa) initn: 161 init1: 66 opt: 115 Z-score: 97.8 bits: 27.9 E(): 3 Smith-Waterman score: 115; 31.250% identity (50.000% similar) in 80 aa overlap (34-113:77-151) 10 20 30 40 50 60 FLJ003 VVSLFSGSWGGCALALCKAIALSVSSAGLWVLAPPEPTGHLVIPGTSPLEPPCPWLDSHI .: :: .:..: :: : KIAA19 AGRRRGRAFSLRVSVMRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIG 50 60 70 80 90 100 70 80 90 100 110 120 FLJ003 FQCRFGKMLPLEKAFASPRSSPAPPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFR : : . :. ..::.. :: : ::.:..::: .:.:: KIAA19 HAVRVGAV-HLQPWTTAPRAASRAPD----DSRAGAQRDEPEPGTRRSPAPSPGARWLGS 110 120 130 140 150 160 130 140 150 160 170 180 FLJ003 EFVYQEAAGPHQTLARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVAQY KIAA19 TLHGRGPPGSRKPGEGARAEALWPRDALLFAVDNLNRVEGLLPYNLSLEVVMAIEAGLGD 170 180 190 200 210 220 >>KIAA1211 ( 803 res) fh00041 (803 aa) initn: 104 init1: 72 opt: 107 Z-score: 93.4 bits: 26.6 E(): 5.3 Smith-Waterman score: 107; 25.683% identity (50.273% similar) in 183 aa overlap (38-214:535-713) 10 20 30 40 50 60 FLJ003 FSGSWGGCALALCKAIALSVSSAGLWVLAPPEPTGHLVIPGTSPLEPPC-PWLDSHIFQC :.::.. : .::: :.: .... KIAA12 GPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQ--TPPASPLSKLSRPYL-VELLSR 510 520 530 540 550 560 70 80 90 100 110 120 FLJ003 RFGKM--LPLEKAFASPRSSPA-PPDLPTPGSAAGVQQEEPETIPERTPADLEFSRLRFR : :. : : . . .:: ::. : : : ...: : :: ::. . . . KIAA12 RAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQE 570 580 590 600 610 620 130 140 150 160 170 180 FLJ003 EFVYQEAAGPHQT--LARLHELCRQWLMPEARSKEQMLELLVLEQFLGILPDKVRPWVVA . :: .. : : : . : .... . . :.:.. :. ... KIAA12 KPSQTPEAGRKEKPMLQSRHSLDGSKLTEKVETAQPLWITLALQKQKGFREQQATREERK 630 640 650 660 670 680 190 200 210 220 230 240 FLJ003 QYPESCKKAASLVEGLADVLEEPGMLLGSPAGSSSILSDGVYERHMDPLLLPGELASPSQ : :. :.: .: . ..: .:: : ::: KIAA12 QAREA-KQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRPETAVSRLERREQLK 690 700 710 720 730 740 250 260 FLJ003 ALGAGEIPAPSETRECPASLAASAGP KIAA12 KANTLPTSVTVEISDSAPPAPLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQ 750 760 770 780 790 800 267 residues in 1 query sequences 2210727 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:51:44 2009 done: Fri Feb 27 10:51:44 2009 Total Scan time: 0.430 Total Display time: 0.050 Function used was FASTA [version 34.26.5 April 26, 2007]