# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sh07610.fasta.huge -Q ../query/FLJ00374.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00374, 260 aa vs ./tmplib.10216 library 2210734 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 3.8421+/-0.00368; mu= 18.5071+/- 0.249 mean_var=77.1993+/-16.458, 0's: 0 Z-trim: 0 B-trim: 0 in 0/40 Lambda= 0.145971 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 36, opt: 24, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA0240 ( 1087 res) fg03390 (1087) 89 28.1 2.4 KIAA0054 ( 1943 res) ha00503s1 (1943) 89 28.5 3.3 KIAA1048 ( 897 res) hh02560 ( 897) 85 27.2 3.8 KIAA0076 ( 1701 res) ha00936 (1701) 87 28.0 4.1 KIAA0487 ( 234 res) fk08362 ( 234) 78 24.8 5 KIAA0872 ( 552 res) hk07213 ( 552) 77 25.2 9.3 KIAA0905 ( 1229 res) hk10341 (1229) 80 26.3 9.4 KIAA0927 ( 1001 res) hg03734 (1001) 79 26.0 9.7 KIAA0458 ( 1552 res) ef01252 (1552) 80 26.5 11 KIAA1116 ( 1330 res) hk02574(revised) (1330) 78 25.9 13 KIAA0689 ( 547 res) hk03417 ( 547) 73 24.3 17 KIAA1142 ( 467 res) hh05864 ( 467) 72 24.0 18 KIAA1758 ( 1662 res) fh20539(revised) (1662) 76 25.7 20 KIAA0263 ( 462 res) pj01112 ( 462) 71 23.8 20 KIAA0015 ( 480 res) ha00478 ( 480) 71 23.8 21 FLJ00210 ( 161 res) sj05028 ( 161) 66 22.1 23 KIAA1760 ( 2219 res) af00030 (2219) 76 25.8 24 KIAA1407 ( 744 res) fh00894(revised) ( 744) 71 24.1 26 KIAA1644 ( 132 res) fg07060 ( 132) 64 21.5 28 KIAA0310 ( 2388 res) ee03470 (2388) 75 25.7 28 KIAA1818 ( 1157 res) hg00622 (1157) 72 24.6 29 KIAA0882 ( 1291 res) hk07544s1 (1291) 72 24.7 31 KIAA0669 ( 825 res) hk02346 ( 825) 70 24.0 32 KIAA1015 ( 841 res) hk03609(revised) ( 841) 70 24.0 33 FLJ00342 ( 233 res) sf00009 ( 233) 65 22.1 33 FLJ00227 ( 196 res) sj06355 ( 196) 64 21.8 35 KIAA0388 ( 751 res) hj00039 ( 751) 69 23.7 35 KIAA0067 ( 1300 res) ha01038 (1300) 71 24.5 36 KIAA1893 ( 800 res) fk04261 ( 800) 69 23.7 37 KIAA0793 ( 1055 res) hk05692 (1055) 70 24.1 37 KIAA0656 ( 912 res) hk01789 ( 912) 69 23.8 39 KIAA1955 ( 947 res) fk07007 ( 947) 69 23.8 40 KIAA1213 ( 484 res) fh01142 ( 484) 66 22.8 43 FLJ00267 ( 1110 res) sj04085 (1110) 69 23.9 44 KIAA0940 ( 699 res) hh04894 ( 699) 67 23.2 45 KIAA0208 ( 748 res) ha02713 ( 748) 67 23.3 47 KIAA0501 ( 122 res) hg00500 ( 122) 60 20.6 47 KIAA1662 ( 1653 res) fj03879s1 (1653) 70 24.4 47 KIAA0874 ( 601 res) hk07302 ( 601) 66 22.9 48 FLJ00354 ( 1041 res) sh02128 (1041) 68 23.7 49 KIAA0703 ( 1051 res) hg02861(revised) (1051) 68 23.7 49 KIAA0357 ( 2992 res) hh00016y2 (2992) 72 25.2 49 KIAA0737 ( 629 res) hk03869 ( 629) 66 22.9 49 KIAA0072 ( 503 res) ha01357 ( 503) 65 22.6 50 KIAA1080 ( 517 res) hj07082 ( 517) 65 22.6 51 KIAA0112 ( 399 res) ha00609 ( 399) 64 22.2 51 KIAA1251 ( 1483 res) hh07943 (1483) 69 24.1 52 KIAA1630 ( 901 res) fh15267(revised) ( 901) 67 23.4 52 KIAA0563 ( 1652 res) fh23589 (1652) 69 24.2 55 KIAA1934 ( 452 res) fk02059 ( 452) 64 22.3 55 >>KIAA0240 ( 1087 res) fg03390 (1087 aa) initn: 45 init1: 45 opt: 89 Z-score: 99.7 bits: 28.1 E(): 2.4 Smith-Waterman score: 89; 29.592% identity (57.143% similar) in 98 aa overlap (6-91:669-760) 10 20 30 FLJ003 QGNDELGSQSPDDKALTASSPMPLSLAGYPQVRAP ::. .:... ...::: :.: :.. KIAA02 TDGLRQAQIPGLLSTTLPGQDSGSKVISASLGTAQPQQEKVVGSSP------GHPAVQVE 640 650 660 670 680 690 40 50 60 70 80 FLJ003 ----GQQ-PQA-QLAMALCLKQVFAKDK--TFRPRKR----FEPGTQRFELYKKAQASLK ::. : : ::. . . : . .:. : : : . ..::. :. :.:. KIAA02 SHSGGQKRPAAKQLTKGAFILQQLQRDQAHTVTPDKSHFRSLSDAVQRLLSYHVCQGSMP 700 710 720 730 740 750 90 100 110 120 130 140 FLJ003 SGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYR . :::.: KIAA02 TEEDLRKVDNEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERA 760 770 780 790 800 810 >>KIAA0054 ( 1943 res) ha00503s1 (1943 aa) initn: 111 init1: 88 opt: 89 Z-score: 97.1 bits: 28.5 E(): 3.3 Smith-Waterman score: 89; 45.000% identity (67.500% similar) in 40 aa overlap (215-254:1559-1598) 190 200 210 220 230 240 FLJ003 VPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVD : :. .:: .:.: :..: .:::.: : KIAA00 GSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRD 1530 1540 1550 1560 1570 1580 250 260 FLJ003 QRELEPLREMTERICH : : . : :: KIAA00 QSETRELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNP 1590 1600 1610 1620 1630 1640 >>KIAA1048 ( 897 res) hh02560 (897 aa) initn: 86 init1: 63 opt: 85 Z-score: 95.9 bits: 27.2 E(): 3.8 Smith-Waterman score: 85; 27.778% identity (50.000% similar) in 72 aa overlap (10-81:423-494) 10 20 30 FLJ003 QGNDELGSQSPDDKALTASSPMPLSLAGYPQVRAPGQQP .: .: . :. . .. : . : :: KIAA10 TTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQP 400 410 420 430 440 450 40 50 60 70 80 90 FLJ003 QAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGEN . : . : :. ::. : . :.:: : .:::. KIAA10 KPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQP 460 470 480 490 500 510 100 110 120 130 140 150 FLJ003 IDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAP KIAA10 PPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQ 520 530 540 550 560 570 >>KIAA0076 ( 1701 res) ha00936 (1701 aa) initn: 106 init1: 51 opt: 87 Z-score: 95.4 bits: 28.0 E(): 4.1 Smith-Waterman score: 87; 33.333% identity (65.079% similar) in 63 aa overlap (33-89:328-387) 10 20 30 40 50 FLJ003 NDELGSQSPDDKALTASSPMPLSLAGYPQVRAPGQ--QPQ-AQLAMALCLKQV---FAKD :.::. ::: :... .: :. : .. KIAA00 EFSMAMGTLISELVQAMRWDQASDRPRSSARSPGSIFQPQLADVSPGLPAAQAQPSFRRS 300 310 320 330 340 350 60 70 80 90 100 110 FLJ003 KTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRIN . ::::..: :. . :: .. .:. :. .: KIAA00 RRFRPRSEFASGNT-YALY--VRDTLQPGMRVRMLDDYEEISAGDEGEFRQSNNGVPPVQ 360 370 380 390 400 410 120 130 140 150 160 170 FLJ003 LIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDE KIAA00 VFWESTGRTYWVHWHMLEILGFEEDIEDMVEADEYQGAVASRVLGRALPAWRWRPMTELY 420 430 440 450 460 470 >>KIAA0487 ( 234 res) fk08362 (234 aa) initn: 67 init1: 67 opt: 78 Z-score: 93.9 bits: 24.8 E(): 5 Smith-Waterman score: 78; 29.851% identity (53.731% similar) in 67 aa overlap (1-62:10-74) 10 20 30 40 FLJ003 QGNDELGSQSPDDKALTASSPMP--LSLAGYPQVRAPGQQPQAQLAMALCL .: . ::..: . : :.: .. :: :. : :: : . : . . KIAA04 PPFPWRLRPEGAEASGSRAPAPD--SPSPPLPGGVAAAGPPRRRPEQQQQQQEPASMMKF 10 20 30 40 50 50 60 70 80 90 100 FLJ003 K--QVFAKDKT-FRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAV : :. . :. :. : KIAA04 KPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAV 60 70 80 90 100 110 >>KIAA0872 ( 552 res) hk07213 (552 aa) initn: 47 init1: 47 opt: 77 Z-score: 89.0 bits: 25.2 E(): 9.3 Smith-Waterman score: 77; 21.429% identity (48.810% similar) in 168 aa overlap (4-169:156-316) 10 20 30 FLJ003 QGNDELGSQSPDDKALTASSPMPLSLAGYPQVR : . . .:. :. . :: :... .. KIAA08 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS 130 140 150 160 170 180 40 50 60 70 80 90 FLJ003 APGQQPQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVR . : ...: : .. ... : :. : ..: . .: .. : . .. KIAA08 QSAAQLRGEL---LAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSME 190 200 210 220 230 240 100 110 120 130 140 150 FLJ003 LPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSET--SCPVMAGGPRYEYRWQDERQYR :: . ::. : . . :.. .::. . :.: : : : ::. KIAA08 QDPGALLLG--AVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQ-ERNVL 250 260 270 280 290 160 170 180 190 200 210 FLJ003 RPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYI .:. : . ::.::. KIAA08 AECRLD-PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLL 300 310 320 330 340 350 >>KIAA0905 ( 1229 res) hk10341 (1229 aa) initn: 53 init1: 53 opt: 80 Z-score: 88.9 bits: 26.3 E(): 9.4 Smith-Waterman score: 80; 25.000% identity (55.952% similar) in 84 aa overlap (19-100:1050-1126) 10 20 30 40 FLJ003 QGNDELGSQSPDDKALTASSPMPLS-LAGYPQVRAPGQQPQAQLAMAL :.:.::: ...:: . :: :: . . KIAA09 PENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQP- 1020 1030 1040 1050 1060 1070 50 60 70 80 90 100 FLJ003 CLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLP-PGENIDDWIAV : :. . .: . ::. . ....:. : ..... : : :.. KIAA09 -LGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQS-----LPTKKITKKPIPDEHLILKTTF 1080 1090 1100 1110 1120 1130 110 120 130 140 150 160 FLJ003 HVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLM KIAA09 EDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYS 1140 1150 1160 1170 1180 1190 >>KIAA0927 ( 1001 res) hg03734 (1001 aa) initn: 96 init1: 48 opt: 79 Z-score: 88.6 bits: 26.0 E(): 9.7 Smith-Waterman score: 79; 28.155% identity (40.777% similar) in 103 aa overlap (1-101:127-221) 10 20 30 FLJ003 QGNDELGSQSPDDKALTASSPMPLSLAGYP :. . :: : : .: .: : KIAA09 YLLPSGAPERGSPGKEHPEERVVTAPPSSSQSAEVLGELVLDGTAPSAHHDIPALSPLLP 100 110 120 130 140 150 40 50 60 70 80 FLJ003 QVRAPGQQ--PQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDL . : . :. .: :::: . : .::. .:: .: :::: KIAA09 EEARPKHALPPKKKLP---SLKQVNSARKQLRPKATSAATVQRAGSQPASQ-----GLDL 160 170 180 190 200 90 100 110 120 130 140 FLJ003 RSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDER : :: : KIAA09 LSSSTEKPGPPGDPDPIVASEEASEVPLWLDRKESAVPTTPAPLQISPFTSQPYVAHTLP 210 220 230 240 250 260 >>KIAA0458 ( 1552 res) ef01252 (1552 aa) initn: 68 init1: 46 opt: 80 Z-score: 87.9 bits: 26.5 E(): 11 Smith-Waterman score: 80; 40.541% identity (59.459% similar) in 37 aa overlap (6-41:720-756) 10 20 30 FLJ003 QGNDELGSQSPDDKALTASSPMPLSLA-GYPQVRA : .: : .: :. .: : : : ::. . KIAA04 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 690 700 710 720 730 740 40 50 60 70 80 90 FLJ003 PGQQPQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRL :: :.: KIAA04 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 750 760 770 780 790 800 >>KIAA1116 ( 1330 res) hk02574(revised) (1330 aa) initn: 60 init1: 37 opt: 78 Z-score: 86.3 bits: 25.9 E(): 13 Smith-Waterman score: 78; 21.965% identity (50.867% similar) in 173 aa overlap (7-172:1-158) 10 20 30 40 50 FLJ003 QGNDELGSQSPDDKALTASSPM-PLSLAGYPQVRAPGQQPQAQLAMALCLKQVFAKDKTF :: :: .:: :. : :. . ::...:... .:: . . . : KIAA11 GSPSPPARAL----PLRPEVAAARSPASAPSSRPRSSPRLALPTQ--CSGRRLF 10 20 30 40 60 70 80 90 100 110 FLJ003 RPRKRFEPG--TQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINL : : : : .. .: : .. : : : . . .: :.... :.... KIAA11 RRRAR---GLRSDNMEAVKTFNSELYSLNDYKPPISKAKMTQITK-AAIKAIKFYKHVVQ 50 60 70 80 90 100 120 130 140 150 160 170 FLJ003 IYGTMAERCS-ETSCP---VMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLI . ..:. : . : :. . : :...:. . . :::. ... ...: KIAA11 SVEKFIQKCKPEYKVPGLYVIDSIVR-----QSRHQFGQEKDVFAPRFSNNIISTFQNLY 110 120 130 140 150 180 190 200 210 220 230 FLJ003 NDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHF KIAA11 RCPGDDKSKIVRVLNLWQKNNVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSNTPGT 160 170 180 190 200 210 260 residues in 1 query sequences 2210734 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 11:02:17 2009 done: Fri Feb 27 11:02:17 2009 Total Scan time: 0.410 Total Display time: 0.060 Function used was FASTA [version 34.26.5 April 26, 2007]