# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sj06165.fasta.huge -Q ../query/FLJ00222.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00222, 656 aa vs ./tmplib.10216 library 2210338 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 8.5044+/-0.0077; mu= 3.0383+/- 0.516 mean_var=413.6327+/-93.557, 0's: 0 Z-trim: 10 B-trim: 0 in 0/40 Lambda= 0.063062 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 38, opt: 26, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) FLJ00414 ( 1129 res) sg00016 (1129) 4515 425.4 1.6e-119 KIAA0450 ( 1182 res) hj05822 (1182) 4079 385.8 1.4e-107 FLJ00417 ( 600 res) sj06336 ( 600) 2995 286.7 4.9e-78 KIAA1069 ( 787 res) hj05486 ( 787) 1500 150.8 5e-37 KIAA1092 ( 1154 res) hk04417 (1154) 826 89.8 1.8e-18 KIAA1964 ( 757 res) ph00746 ( 757) 735 81.2 4.3e-16 KIAA0581 ( 1218 res) pf10976 (1218) 577 67.2 1.2e-11 KIAA1516 ( 2304 res) fh10631s2 (2304) 482 58.9 6.7e-09 KIAA1522 ( 1044 res) fh14706(revised) (1044) 209 33.6 0.13 KIAA1870 ( 832 res) hh05136b ( 832) 185 31.2 0.53 KIAA1802 ( 821 res) fj21631 ( 821) 173 30.1 1.1 KIAA1029 ( 1015 res) fh00363 (1015) 171 30.1 1.4 KIAA1236 ( 1840 res) pg00641 (1840) 173 30.7 1.7 KIAA1261 ( 787 res) hh15855b ( 787) 162 29.1 2.2 KIAA0434 ( 1571 res) hh02165 (1571) 162 29.6 3.2 FLJ00201 ( 705 res) sj04110 ( 705) 152 28.1 3.9 KIAA0985 ( 697 res) hj08038 ( 697) 150 27.9 4.4 KIAA1887 ( 967 res) fk02232 ( 967) 152 28.3 4.6 FLJ00252 ( 819 res) sj09394 ( 819) 150 28.0 4.8 FLJ00378 ( 855 res) sj00210 ( 855) 150 28.1 4.9 KIAA1471 ( 1421 res) fj02383s1 (1421) 153 28.7 5.3 KIAA1908 ( 445 res) ah02604 ( 445) 142 26.9 5.7 KIAA1768 ( 1207 res) ph00672(revised) (1207) 150 28.3 5.9 KIAA1878 ( 453 res) pj01649 ( 453) 138 26.6 7.4 KIAA1433 ( 652 res) hh05535 ( 652) 141 27.1 7.4 KIAA0665 ( 760 res) hk02064 ( 760) 142 27.3 7.6 KIAA1727 ( 1130 res) pg00153 (1130) 145 27.8 7.7 FLJ00176 ( 403 res) sj00934 ( 403) 136 26.3 7.9 KIAA0269 ( 567 res) ha06751 ( 567) 138 26.7 8.3 KIAA1760 ( 2219 res) af00030 (2219) 149 28.6 8.6 KIAA0093 ( 927 res) ha00935 ( 927) 140 27.2 9.5 KIAA0346 ( 1682 res) hg01508s1 (1682) 145 28.1 9.6 KIAA1862 ( 1070 res) aj00563 (1070) 141 27.4 9.7 FLJ00086 ( 399 res) as00086 ( 399) 131 25.8 11 FLJ00072 ( 204 res) as00072 ( 204) 125 24.8 11 KIAA0945 ( 797 res) hj04760 ( 797) 136 26.8 11 KIAA1940 ( 821 res) ah04227 ( 821) 136 26.8 12 FLJ00353 ( 1766 res) sh01144 (1766) 142 27.8 12 FLJ00084 ( 641 res) as00084 ( 641) 133 26.3 12 KIAA1614 ( 1208 res) fj12973 (1208) 137 27.1 13 KIAA1056 ( 870 res) hh11792 ( 870) 133 26.5 14 KIAA0905 ( 1229 res) hk10341 (1229) 135 27.0 15 KIAA1856 ( 1134 res) fh03203 (1134) 134 26.8 16 KIAA2036 ( 1322 res) pf06513 (1322) 134 26.9 17 KIAA1075 ( 1505 res) hj06716s1 (1505) 135 27.1 17 KIAA0672 ( 824 res) hk02382 ( 824) 129 26.1 18 KIAA1543 ( 917 res) hh05613a ( 917) 129 26.2 19 KIAA0821 ( 1566 res) hh02631 (1566) 133 26.9 20 FLJ00420 ( 613 res) sj09535 ( 613) 125 25.6 20 FLJ00318 ( 127 res) sh07374 ( 127) 111 23.3 20 >>FLJ00414 ( 1129 res) sg00016 (1129 aa) initn: 4515 init1: 4515 opt: 4515 Z-score: 2239.1 bits: 425.4 E(): 1.6e-119 Smith-Waterman score: 4515; 99.543% identity (100.000% similar) in 656 aa overlap (1-656:474-1129) 10 20 30 FLJ002 AEEEMESGEDAGASRRNGRLVVGSFSRRKK :::..::::::::::::::::::::::::: FLJ004 KESKIRDCEDPNNFSVSTLSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKK 450 460 470 480 490 500 40 50 60 70 80 90 FLJ002 KGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 KGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEA 510 520 530 540 550 560 100 110 120 130 140 150 FLJ002 ASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 ASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQM 570 580 590 600 610 620 160 170 180 190 200 210 FLJ002 VALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 VALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRII 630 640 650 660 670 680 220 230 240 250 260 270 FLJ002 SGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 SGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMV 690 700 710 720 730 740 280 290 300 310 320 330 FLJ002 HMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 HMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDIS 750 760 770 780 790 800 340 350 360 370 380 390 FLJ002 GKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFP :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 GKVKQVLGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFP 810 820 830 840 850 860 400 410 420 430 440 450 FLJ002 ELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 ELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLR 870 880 890 900 910 920 460 470 480 490 500 510 FLJ002 VLDGPGPAGMAATCMKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 VLDGPGPAGMAATCMKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGA 930 940 950 960 970 980 520 530 540 550 560 570 FLJ002 PCCGLDPHAIPGRSREAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 PCCGLDPHAIPGRSREAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQ 990 1000 1010 1020 1030 1040 580 590 600 610 620 630 FLJ002 PGALQGEMSALFAQKLEEIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 PGALQGEMSALFAQKLEEIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSP 1050 1060 1070 1080 1090 1100 640 650 FLJ002 RVLVLVALYPWHCLRGTLLPWLACGP :::::::::::::::::::::::::: FLJ004 RVLVLVALYPWHCLRGTLLPWLACGP 1110 1120 >>KIAA0450 ( 1182 res) hj05822 (1182 aa) initn: 4079 init1: 4079 opt: 4079 Z-score: 2024.5 bits: 385.8 E(): 1.4e-107 Smith-Waterman score: 4079; 99.498% identity (99.833% similar) in 598 aa overlap (1-598:582-1179) 10 20 30 FLJ002 AEEEMESGEDAGASRRNGRLVVGSFSRRKK :::..::::::::::::::::::::::::: KIAA04 KESKIRDCEDPNNFSVSTLSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKK 560 570 580 590 600 610 40 50 60 70 80 90 FLJ002 KGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 KGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEA 620 630 640 650 660 670 100 110 120 130 140 150 FLJ002 ASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 ASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQM 680 690 700 710 720 730 160 170 180 190 200 210 FLJ002 VALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 VALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRII 740 750 760 770 780 790 220 230 240 250 260 270 FLJ002 SGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 SGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMV 800 810 820 830 840 850 280 290 300 310 320 330 FLJ002 HMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 HMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDIS 860 870 880 890 900 910 340 350 360 370 380 390 FLJ002 GKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 GKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFP 920 930 940 950 960 970 400 410 420 430 440 450 FLJ002 ELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : KIAA04 ELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPR 980 990 1000 1010 1020 1030 460 470 480 490 500 510 FLJ002 VLDGPGPAGMAATCMKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 VLDGPGPAGMAATCMKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGA 1040 1050 1060 1070 1080 1090 520 530 540 550 560 570 FLJ002 PCCGLDPHAIPGRSREAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA04 PCCGLDPHAIPGRSREAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQ 1100 1110 1120 1130 1140 1150 580 590 600 610 620 630 FLJ002 PGALQGEMSALFAQKLEEIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSP :::::::::::::::::::::::::::: KIAA04 PGALQGEMSALFAQKLEEIRSKSPMFSAVRN 1160 1170 1180 >>FLJ00417 ( 600 res) sj06336 (600 aa) initn: 2985 init1: 2985 opt: 2995 Z-score: 1494.4 bits: 286.7 E(): 4.9e-78 Smith-Waterman score: 2995; 93.506% identity (96.753% similar) in 462 aa overlap (198-656:140-600) 170 180 190 200 210 220 FLJ002 KFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR- :.. ... . : : :.. . :.: . .: FLJ004 GMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRY 110 120 130 140 150 160 230 240 250 260 270 280 FLJ002 --GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD : . :::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 PDGSF-DPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWD 170 180 190 200 210 220 290 300 310 320 330 340 FLJ002 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 HDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFL 230 240 250 260 270 280 350 360 370 380 390 400 FLJ002 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 RGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGV 290 300 310 320 330 340 410 420 430 440 450 460 FLJ002 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 ADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATC 350 360 370 380 390 400 470 480 490 500 510 520 FLJ002 MKCVVGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRS ::::::::::::::::.:::::::::::::::::::::::::::::::::::::.::::: FLJ004 MKCVVGSCAGVNTGGLHRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHGIPGRS 410 420 430 440 450 460 530 540 550 560 570 580 FLJ002 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 REAPKGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQ 470 480 490 500 510 520 590 600 610 620 630 640 FLJ002 KLEEIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSPRVLVLVALYPWHCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: FLJ004 KLEEIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSPRVLVLVALYPWHCL 530 540 550 560 570 580 650 FLJ002 RGTLLPWLACGP :::::::::::: FLJ004 RGTLLPWLACGP 590 600 >>KIAA1069 ( 787 res) hj05486 (787 aa) initn: 1606 init1: 1347 opt: 1500 Z-score: 758.2 bits: 150.8 E(): 5e-37 Smith-Waterman score: 1606; 58.795% identity (80.723% similar) in 415 aa overlap (15-406:327-737) 10 20 30 40 FLJ002 AEEEMESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEG . .:: .. .:...:: .. .:. :... KIAA10 SFTVRALLKATHEGLNAHLKQSPDVKESGKKSHGRSLMTNFGKHKKTTKSRSKSYSTDDE 300 310 320 330 340 350 50 60 70 80 90 100 FLJ002 DEGQDSPG---GQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSE .. :.: : :: :..::::: : ::::: ::.:::..:: .. ... .: :::: KIAA10 EDTQQSTGKEGGQLYRLGRRRKTMKLCRELSDLVVYTNSVAAQDI-VDDGTTGNVLSFSE 360 370 380 390 400 410 110 120 130 140 150 160 FLJ002 TKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRM :.:::..::: :.. .::.::.:::::.::.::::.:: :.::::::.::::::::::: KIAA10 TRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRM 420 430 440 450 460 470 170 180 190 200 210 220 FLJ002 LQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDS .:::::::.:::.::::::: ::.:.::: : ::::.. ::::.:..::::::::: :: KIAA10 MQLNRAKFKANGNCGYVLKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQLPKPPDS 480 490 500 510 520 530 230 240 250 260 270 280 FLJ002 MLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFL :.:::::::::::::::::::::: ..::::::::::::.:::::.: :::::::::::: KIAA10 MFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFL 540 550 560 570 580 590 290 300 310 320 330 FLJ002 VWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKV-------- :::::::::::.::::..:::..::::::::::. :::::::.....: :: KIAA10 VWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIYGKWSPLILNPS 600 610 620 630 640 650 340 350 360 370 380 FLJ002 ------------KQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKS .: :::::: ..:. .: :. .. . :...::::::::::.:. KIAA10 YTILHFLGATKNRQLQGLKGLFNKNPRHSS--SENNSHYVRKRSIGDRILRRTASAPAKG 660 670 680 690 700 710 390 400 410 420 430 440 FLJ002 QKPGRRGFPELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEK .: .. :: :.: .:. :... : KIAA10 RKKSKMGFQEMVE-IKDSVSEATRDQDGVLRRTTRSLQARPVSMPVDRNLLGALSLPVSE 720 730 740 750 760 770 >>KIAA1092 ( 1154 res) hk04417 (1154 aa) initn: 675 init1: 636 opt: 826 Z-score: 425.2 bits: 89.8 E(): 1.8e-18 Smith-Waterman score: 833; 36.111% identity (68.182% similar) in 396 aa overlap (31-406:595-982) 10 20 30 40 50 FLJ002 AEEEMESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPGG---QSRG :..::.. : ::: ... :. : : KIAA10 LLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMG 570 580 590 600 610 620 60 70 80 90 100 FLJ002 ATRQK-------KTMKLSRALSDLVKYTKSVATHDIEM--EAASSWQVSSFSETKAHQIL .. : ..: . ::.::. ::: ..... .. . :.: ::.:. : . KIAA10 KENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYA 630 640 650 660 670 680 110 120 130 140 150 160 FLJ002 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK ...:.... .:.. :.:..:: .:.::::.::: ::. :::.::.:.:. : :..:: . KIAA10 NENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGW 690 700 710 720 730 740 170 180 190 200 210 220 FLJ002 FSANGGCGYVLKPGCMCQGV--FNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDR : ::.:::::.:. : . : :. :..: .:: . : ..:::::..:::. : : . KIAA10 FRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGS--GAK 750 760 770 780 790 800 230 240 250 260 270 280 FLJ002 GEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHD :...::.: ::: :.:.::....:..: .:: : ..:.. :....::.:.:::.: : : KIAA10 GDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDD 810 820 830 840 850 860 290 300 310 320 330 340 FLJ002 PIGRDFIGQRTLAFSSMMPGYRHVYLEGME-----EASIFVHVAVSDISGKVKQALGLKG :: .:::: :. : .. ::::: :... .::.:::::... : : .: KIAA10 YIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPH--KRG 870 880 890 900 910 920 350 360 370 380 390 400 FLJ002 LFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDT-G : .: : . .:. : .:.. . ..:. : .. :... . :.. .. : KIAA10 LSVRKGKKSR--EYASLRTLWIKTVDE--VFKNAQPPIRDATDLRENMQNAVVSFKELCG 930 940 950 960 970 410 420 430 440 450 460 FLJ002 SKGVADDVVPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGM ..::. KIAA10 LSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQ 980 990 1000 1010 1020 1030 >>KIAA1964 ( 757 res) ph00746 (757 aa) initn: 742 init1: 355 opt: 735 Z-score: 382.2 bits: 81.2 E(): 4.3e-16 Smith-Waterman score: 735; 38.710% identity (70.323% similar) in 310 aa overlap (28-326:456-754) 10 20 30 40 50 FLJ002 AEEEMESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPGGQSRG :.. : :. :: :: .. . .. KIAA19 ALDSPNPEELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEEDDEEEEE---EVEA 430 440 450 460 470 480 60 70 80 90 100 110 FLJ002 ATRQKKTMKLSRALSDLVKYTKSVATHDIEM--EAASSWQVSSFSETKAHQILQQKPAQY :.... . ..: :: :. : ... . .. .: . ::::.:: ::...... .. KIAA19 AAQRRLAKQISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF 490 500 510 520 530 540 120 130 140 150 160 170 FLJ002 LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC .: : .::.:.:: . :..:.::.:: .::.:::.::::.:. : ..:: ..: .:: : KIAA19 VRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQC 550 560 570 580 590 600 180 190 200 210 220 230 FLJ002 GYVLKPGCMCQGVFNPNSE-DP-LPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE-IIDP ::::::.:. : :.: :: :: . : ......::::: . ... . :.:: KIAA19 GYVLKPACLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPK----LNAEKPHSIVDP 610 620 630 640 650 240 250 260 270 280 290 FLJ002 FVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIG-RD .:..:: :.:.::.:..: : .::::: : .:: :... ::.:::::.: :.: . : KIAA19 LVRIEIHGVPADCARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPND 660 670 680 690 700 710 300 310 320 330 340 FLJ002 FIGQRTLAFSSMMPGYRHVYL---EG--MEEASIFVHVAVSDISGKVKQALGLKGLFLRG :.:: :: .::. ::::..: .: . :..:... . KIAA19 FVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFIQIRIQRS 720 730 740 750 350 360 370 380 390 400 FLJ002 PKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVAD >>KIAA0581 ( 1218 res) pf10976 (1218 aa) initn: 492 init1: 337 opt: 577 Z-score: 302.5 bits: 67.2 E(): 1.2e-11 Smith-Waterman score: 577; 36.000% identity (66.333% similar) in 300 aa overlap (42-328:514-799) 20 30 40 50 60 70 FLJ002 GASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRAL .. :. .: .. .: ...: .. . KIAA05 LSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMA-TEEM 490 500 510 520 530 540 80 90 100 110 120 FLJ002 SDLVKYTKSVATHDIEM--EAASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPS :.::.: . : ...:. . .:...::: :::. . : ..:......:..:::::::. KIAA05 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK 550 560 570 580 590 600 130 140 150 160 170 180 FLJ002 SYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGV- . ::::::: :: ::::::::::::.:. .:.: . . :: :: ::: : . KIAA05 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK 610 620 630 640 650 660 190 200 210 220 230 240 FLJ002 -FNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSR :.: .: . : . . : ..::::: .:.:. . .:::...::::: : KIAA05 HFDPFTEGIVDGIVANTLSVKIISGQ--------FLSDKK--VGTYVEVDMFGLPVDTRR 670 680 690 700 710 250 260 270 280 290 300 FLJ002 E--QTRVVDDNGFNPTWEET-LVFM-VHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSM . .:.. . :. ::.::: .:: : .: .: .:. :... : :::.: : ... KIAA05 KAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEE---GGKFIGHRILPVQAI 720 730 740 750 760 310 320 330 340 350 FLJ002 MPGYRHVYLEG-----MEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAG :::... :.. . ..::.. :.: KIAA05 RPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQL 770 780 790 800 810 820 >>KIAA1516 ( 2304 res) fh10631s2 (2304 aa) initn: 450 init1: 254 opt: 482 Z-score: 253.1 bits: 58.9 E(): 6.7e-09 Smith-Waterman score: 482; 31.046% identity (61.438% similar) in 306 aa overlap (31-323:1692-1986) 10 20 30 40 50 FLJ002 AEEEMESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPG-GQSRGAT .:.. :. :. .. :. ::: : . : KIAA15 QIAPELSDLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKT 1670 1680 1690 1700 1710 1720 60 70 80 90 100 110 FLJ002 RQKKTMK-LSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQILQQKPAQYLRF :.. . . .. . . . ... . ... . ...::..:. :... .. . . KIAA15 SGKSSCEGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQH 1730 1740 1750 1760 1770 1780 120 130 140 150 160 170 FLJ002 NQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYV . :: : ::.. :.:::: :: :: : :.::::::.. :.:: : : :::::::: KIAA15 TACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYV 1790 1800 1810 1820 1830 1840 180 190 200 210 220 230 FLJ002 LKP------GCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDP ::: .: :.: .: : .. : :.:::.. : .:: : .: KIAA15 LKPPVLWDKNCPMYQKFSPLERD-LDSMDPAVYSLTIVSGQNV-CPSNSM-G------SP 1850 1860 1870 1880 1890 240 250 260 270 280 290 FLJ002 FVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDF .::...:.:.: . .:. . : .:: :.: ..: ::. .....:: : ... . KIAA15 CIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENN--SSAV 1900 1910 1920 1930 1940 1950 300 310 320 330 340 FLJ002 IGQRTLAFSSMMPGYRHVYL-----EGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGP .:: . .... ::::. : : .: .:.:.. KIAA15 TAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRMEENSSGNTMSASSMFNTEER 1960 1970 1980 1990 2000 2010 350 360 370 380 390 400 FLJ002 KPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADD KIAA15 KCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQLLQQILTNEQDIKPVTTDYFLMEEKYFI 2020 2030 2040 2050 2060 2070 >>KIAA1522 ( 1044 res) fh14706(revised) (1044 aa) initn: 232 init1: 97 opt: 209 Z-score: 122.2 bits: 33.6 E(): 0.13 Smith-Waterman score: 210; 27.551% identity (46.599% similar) in 294 aa overlap (347-622:725-994) 320 330 340 350 360 370 FLJ002 EASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTAS : : : : :: . . ... KIAA15 KKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFF------SVA 700 710 720 730 740 380 390 400 410 420 430 FLJ002 APTKSQKPGRRGFPELVLGTRDTGSKGVADDVVPPG---PGPAPEAPAQEGPGSGSPRGK .: . : : :::: . ..:...: .. ::: : ::: ::: : .. KIAA15 SP---EPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA--------PASS 750 760 770 780 790 440 450 460 470 480 490 FLJ002 APAAVAEKSPVRVRPLRVLDGPGPA--GMAATCMKCVVGSCAGVNTGGLQRERP-PSPGP ::. :: : : . .:. : :: ..: . . . . . . : : :. :: KIAA15 APGHVA-KLPQK-EPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGP 800 810 820 830 840 850 500 510 520 530 540 FLJ002 ASRQAAIRQQPRARADSLGAPCCGLDPH---------AIPGRSREAPKGPG-AWRQGPGG .. : .:. .::. . :: :: : : : :.:: : . : . KIAA15 SAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS 860 870 880 890 900 910 550 560 570 580 590 600 FLJ002 SGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEEIRSKSPMFSAGK .: .: : : . . : :: : .:. .. :. . .::: .: KIAA15 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP--KAPP 920 930 940 950 960 970 610 620 630 640 650 FLJ002 PLL--PCVVLPHAPGMAGPGSPAAASAWTVSPRVLVLVALYPWHCLRGTLLPWLACGP :. : : .: : :.:. : : KIAA15 PVARKPSVGVP-PP--ASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEE 980 990 1000 1010 1020 1030 >>KIAA1870 ( 832 res) hh05136b (832 aa) initn: 124 init1: 88 opt: 185 Z-score: 111.4 bits: 31.2 E(): 0.53 Smith-Waterman score: 194; 29.231% identity (51.538% similar) in 260 aa overlap (345-577:25-276) 320 330 340 350 360 370 FLJ002 MEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPS--VSQRILR ::: :: . . . : : :. .... : KIAA18 GGHPGMPGGMGTPGEPGPQGPPGSRGP-PG-MRGAKGRRGPRGPDGPAGEQGSR 10 20 30 40 50 380 390 400 410 420 FLJ002 RTASAPTKSQKPGRRGFPELVLGTRD-TGSKG---VADDVVPPG----PG-PAPEAPAQE . : . .::: : . : : : ::.: . ::: :: :.:..: KIAA18 GLKGPPGPQGRPGRPG-QQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 60 70 80 90 100 110 430 440 450 460 470 FLJ002 -GP-GSGSPRGKAPAAVAEKS-PVRVR---PLRVLDGPGPAGMAATCMK-CVVGSCAGVN :: : .:.: :.::.: . : .. : : :: :. . . . :. . .. KIAA18 IGPPGEMGPKGP-PGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG 120 130 140 150 160 170 480 490 500 510 520 FLJ002 TGGLQRERPPSPGPASRQAAIRQQPRARADSLGAP--CCGL-DPHAIPGRS----REAPK ::. .: .::: .... :. :. .: :. :.. :.. : . : KIAA18 PDGLKGDRG-DPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAK 180 190 200 210 220 530 540 550 560 570 580 FLJ002 GPGAWRQGPGGSGSMSSDSSSPDSPGIPE--RSPRWPEGACRQPGALQGEMSALFAQKLE : .. :: : .. .: . : .:: :. :. : :: . :: ::: KIAA18 GAKGY-QGQLGEMGVPGDPGPPGTPG-PKGSRGSLGPTGAPGRMGA-QGEPGLAGYDGHK 230 240 250 260 270 280 590 600 610 620 630 640 FLJ002 EIRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSPRVLVLVALYPWHCLRGT KIAA18 GIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGL 290 300 310 320 330 340 656 residues in 1 query sequences 2210338 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:44:51 2009 done: Fri Feb 27 10:44:51 2009 Total Scan time: 0.650 Total Display time: 0.210 Function used was FASTA [version 34.26.5 April 26, 2007]