# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sj07756.fasta.huge -Q ../query/FLJ00244.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00244, 1124 aa vs ./tmplib.10216 library 2209870 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 4.8103+/-0.00426; mu= 20.3498+/- 0.286 mean_var=110.1775+/-24.667, 0's: 0 Z-trim: 10 B-trim: 15 in 1/39 Lambda= 0.122188 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 39, opt: 27, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1769 ( 2114 res) af00171 (2114) 7675 1364.9 0 KIAA0054 ( 1943 res) ha00503s1 (1943) 362 75.7 8.8e-14 KIAA1631 ( 1032 res) fh15959s1 (1032) 275 60.0 2.5e-09 KIAA0083 ( 1077 res) ha03631 (1077) 198 46.4 3.1e-05 KIAA0221 ( 1151 res) ha02799 (1151) 188 44.7 0.00011 KIAA1008 ( 935 res) hh04776s1 ( 935) 175 42.3 0.00048 KIAA1955 ( 947 res) fk07007 ( 947) 170 41.4 0.00089 FLJ00247 ( 925 res) sj08552 ( 925) 144 36.8 0.021 KIAA1404 ( 1925 res) eg01672 (1925) 138 36.2 0.067 FLJ00327 ( 266 res) sj02293 ( 266) 125 32.7 0.1 KIAA0625 ( 2663 res) hg04796s1 (2663) 118 32.9 0.94 KIAA0560 ( 1521 res) hj07625 (1521) 114 31.8 1.1 KIAA1668 ( 791 res) fh11717 ( 791) 110 30.7 1.2 KIAA1286 ( 1214 res) hh11961(revised) (1214) 108 30.6 2 KIAA1762 ( 1460 res) fh27937(revised) (1460) 104 30.0 3.6 FLJ00206 ( 702 res) sj04644 ( 702) 100 28.9 3.9 KIAA1635 ( 1435 res) fh23184(revised) (1435) 101 29.5 5.2 KIAA1224 ( 997 res) fh02652 ( 997) 98 28.8 6 KIAA0216 ( 2067 res) hf00331s1 (2067) 100 29.5 7.3 KIAA0429 ( 666 res) hk07754 ( 666) 94 27.8 7.8 KIAA0807 ( 1329 res) hk04449(revised) (1329) 97 28.8 8.1 KIAA1531 ( 1206 res) ph00937 (1206) 96 28.5 8.6 KIAA0557 ( 493 res) hh01334 ( 493) 91 27.1 9.4 KIAA1277 ( 1039 res) fj11251 (1039) 94 28.1 10 KIAA1912 ( 589 res) fj18220 ( 589) 91 27.2 10 KIAA0146 ( 918 res) ha03238 ( 918) 93 27.8 11 KIAA1197 ( 1487 res) fg01844 (1487) 95 28.5 11 KIAA1047 ( 2348 res) hh01221s1 (2348) 97 29.1 11 KIAA0367 ( 820 res) hh00141s1 ( 820) 91 27.4 13 KIAA1878 ( 453 res) pj01649 ( 453) 88 26.5 13 KIAA1522 ( 1044 res) fh14706(revised) (1044) 92 27.7 13 KIAA1853 ( 708 res) hj04155 ( 708) 90 27.1 13 FLJ00170 ( 1310 res) sh07968 (1310) 92 27.9 15 KIAA1583 ( 435 res) fj06651 ( 435) 85 26.0 18 KIAA0633 ( 1316 res) hj02892 (1316) 90 27.5 19 KIAA1868 ( 463 res) fj22550 ( 463) 84 25.8 21 FLJ00045 ( 272 res) as00045 ( 272) 81 25.0 23 KIAA0573 ( 451 res) hj00186 ( 451) 83 25.6 24 KIAA0992 ( 772 res) hk07554 ( 772) 85 26.3 25 KIAA0458 ( 1552 res) ef01252 (1552) 88 27.3 26 FLJ00353 ( 1766 res) sh01144 (1766) 88 27.3 29 KIAA1760 ( 2219 res) af00030 (2219) 89 27.7 29 KIAA0330 ( 2224 res) hg00894s1 (2224) 89 27.7 29 KIAA0915 ( 846 res) hk06275s1 ( 846) 84 26.2 30 FLJ00280 ( 440 res) sh01728 ( 440) 80 25.1 34 KIAA0310 ( 2388 res) ee03470 (2388) 88 27.5 34 FLJ00369 ( 700 res) sh06511 ( 700) 82 25.7 34 KIAA0646 ( 486 res) hj03808 ( 486) 80 25.2 36 KIAA0794 ( 490 res) hk06006 ( 490) 80 25.2 36 FLJ00111 ( 334 res) as00111 ( 334) 78 24.6 36 >>KIAA1769 ( 2114 res) af00171 (2114 aa) initn: 7675 init1: 7675 opt: 7675 Z-score: 7307.5 bits: 1364.9 E(): 0 Smith-Waterman score: 7675; 99.822% identity (99.911% similar) in 1124 aa overlap (1-1124:991-2114) 10 20 30 FLJ002 KEYMIQFNRLVAEFLVGSECTRTVTPLRWQ :::::::::::::::::::::::::::::: KIAA17 LRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQ 970 980 990 1000 1010 1020 40 50 60 70 80 90 FLJ002 PAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 PAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDY 1030 1040 1050 1060 1070 1080 100 110 120 130 140 150 FLJ002 EQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 EQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPI 1090 1100 1110 1120 1130 1140 160 170 180 190 200 210 FLJ002 RRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 RRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKA 1150 1160 1170 1180 1190 1200 220 230 240 250 260 270 FLJ002 QPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 QPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLW 1210 1220 1230 1240 1250 1260 280 290 300 310 320 330 FLJ002 RRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 RRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEASQ 1270 1280 1290 1300 1310 1320 340 350 360 370 380 390 FLJ002 RRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 RRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEH 1330 1340 1350 1360 1370 1380 400 410 420 430 440 450 FLJ002 VERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 VERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEA 1390 1400 1410 1420 1430 1440 460 470 480 490 500 510 FLJ002 SRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNV :::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: KIAA17 SRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLLAPTASPRPGPSSLGPGLNV 1450 1460 1470 1480 1490 1500 520 530 540 550 560 570 FLJ002 DPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLP :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: KIAA17 DPGTYTWVAHGQTEDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLP 1510 1520 1530 1540 1550 1560 580 590 600 610 620 630 FLJ002 KQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 KQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNP 1570 1580 1590 1600 1610 1620 640 650 660 670 680 690 FLJ002 SQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 SQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPC 1630 1640 1650 1660 1670 1680 700 710 720 730 740 750 FLJ002 ILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 ILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPN 1690 1700 1710 1720 1730 1740 760 770 780 790 800 810 FLJ002 QSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 QSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHE 1750 1760 1770 1780 1790 1800 820 830 840 850 860 870 FLJ002 VILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 VILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPV 1810 1820 1830 1840 1850 1860 880 890 900 910 920 930 FLJ002 VKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 VKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPS 1870 1880 1890 1900 1910 1920 940 950 960 970 980 990 FLJ002 VLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 VLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEP 1930 1940 1950 1960 1970 1980 1000 1010 1020 1030 1040 1050 FLJ002 QDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 QDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQR 1990 2000 2010 2020 2030 2040 1060 1070 1080 1090 1100 1110 FLJ002 PTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA17 PTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVP 2050 2060 2070 2080 2090 2100 1120 FLJ002 AGQVRVCRRPTMPS :::::::::::::: KIAA17 AGQVRVCRRPTMPS 2110 >>KIAA0054 ( 1943 res) ha00503s1 (1943 aa) initn: 409 init1: 155 opt: 362 Z-score: 340.8 bits: 75.7 E(): 8.8e-14 Smith-Waterman score: 400; 26.656% identity (51.373% similar) in 619 aa overlap (522-1108:547-1078) 500 510 520 530 540 550 FLJ002 APTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGME ::: .. : . ..:.. .. : KIAA00 TLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLR-LSRE 520 530 540 550 560 570 560 570 580 590 600 FLJ002 KVPEEVLRPGTLFTVELLPK--QLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI : ::: ::: . .:: . . :. ... . : .:.. .: KIAA00 CCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWS----- 580 590 600 610 620 630 610 620 630 640 650 660 FLJ002 PSRFLERQTYNIPGGRHKLNPSQNVAVRE-----ALEKPFTVIQGPPGTGKTIVGLHIVF :.: ..: : .:: .:. :: :.. : ..: :: ::::: : KIAA00 PNRQWDEQLD--P----RLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKT-------F 640 650 660 670 670 680 690 700 710 720 FLJ002 WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA . .. .. .: . : : :: : ::...: : .. . :.: : : . KIAA00 TLAQAVKHILQ-----QQETR-----ILICTHSNSAAD----LYIKDY-LHP---YVEAG 680 690 700 710 730 740 750 760 770 780 FLJ002 EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE . . :. :: : :. .... : . . :: ..: . KIAA00 NPQARPL-RVYFR------------NRWVKTV---HPVVHQYCLISSAHSTF-------Q 720 730 740 750 790 800 810 820 830 FLJ002 LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVR-----QILVDEAGM . ..::.. .:.:.. : . .: : ::.. .::.:::.. KIAA00 MPQKEDIL---------------KHRVVVVTLN--TSQYLCQLDLEPGFFTHILLDEAAQ 760 770 780 790 840 850 860 870 880 890 FLJ002 ATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNE--RLQNLG---LDRSLFERYHEDAH : : ::..::. : ..:: ::: :: : : .: : .:: ::: :.:.: . KIAA00 AMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDR-LYEHYPAEFP 800 810 820 830 840 850 900 910 920 930 940 950 FLJ002 ---MLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHE .: .:: ::.: . : ::..:: . .: ..: : :. :. : ..:.. KIAA00 CRILLCENYRSHEAIINYTSELFYEGKLMA-SG-KQP------AHKDFYPLTFFTARGED 860 870 880 890 900 910 960 970 980 990 1000 1010 FLJ002 RSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALR . :: :. .. : .: .: .. :. .. .:.:.::: :. .: :: KIAA00 VQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGK-LDDGSIGVVTPYADQVFRIRAELR 920 930 940 950 960 1020 1030 1040 1050 1060 FLJ002 REGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF--------LGFV .. .. : : . . ::...: ...::::: : : :. . . ::. KIAA00 KKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFL 970 980 990 1000 1010 1020 1070 1080 1090 1100 1110 FLJ002 VDPNQVNVAVTRAQEGLCLIGDHLLL----RCCPLWRSLLDFCEAQQTLVPAGQVRVCRR . . .:.:.:::: . ..:: . : :: .:. .. .:. ...: KIAA00 SNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQ 1030 1040 1050 1060 1070 1080 1120 FLJ002 PTMPS KIAA00 LEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQ 1090 1100 1110 1120 1130 1140 >>KIAA1631 ( 1032 res) fh15959s1 (1032 aa) initn: 336 init1: 141 opt: 275 Z-score: 260.8 bits: 60.0 E(): 2.5e-09 Smith-Waterman score: 417; 26.849% identity (50.482% similar) in 622 aa overlap (535-1103:436-968) 510 520 530 540 550 FLJ002 GPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEV------- :: : . :::.. ...: KIAA16 LTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSR 410 420 430 440 450 460 560 570 580 590 600 610 FLJ002 LRPGTLFTVELLPKQLPDLRKEEAVRGLEEAS-----PLVTSIALGRPVPQPLCRVIPSR . : : :.. .. : :: .. :.:: .. :.. .: : :: : . . KIAA16 FVDGLTFKVNFTFNRQP-LRVQH--RALELTGRWLLWPMLFPVA-PRDVPL-LPSDVKLK 470 480 490 500 510 520 620 630 640 650 660 670 FLJ002 FLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQE . .:. . : ..:. ..... . :. .: ::::::::.. .. . . KIAA16 LYDRSLESNP---EQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------K 530 540 550 560 680 690 700 710 720 730 FLJ002 QVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVP :: :.: :: :.:::...:.: : :..: : .: : : KIAA16 QVV--------KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLA-----P-- 570 580 590 600 610 740 750 760 770 780 790 FLJ002 RVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLV :: . : :.. .: . .:.. .:: KIAA16 ---SRDI-RMVPEDIKPCCN-----------------------WDAK--KGEY------- 620 630 800 810 820 830 840 FLJ002 WYKKVLWEARKFELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPL .. :.: .:....:.. : :. ::.. : .:..:::: :::.:. . KIAA16 -----VFPAKK-KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAI 640 650 660 670 680 850 860 870 880 890 FLJ002 VQFPQAE-------KVVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHM . . ... ..:: :: .:: ::... :. :: ::.:: :.. KIAA16 AGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDG 690 700 710 720 730 740 900 910 920 930 940 FLJ002 LDTQ--------YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFG : : :: : : .:. .:...:.. . :: ... :.:: KIAA16 YDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFH 750 760 770 780 790 800 950 960 970 980 990 FLJ002 HVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTL-----GRT-VEPQDIAVLTPY :.:... ::: : : ::.: :. : : :.. . :....:..:: KIAA16 GVMGKDER------EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPY 810 820 830 840 850 860 1000 1010 1020 1030 1040 1050 FLJ002 NAQASEIS---KALRRE-----GIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRP :. .: : :: : . :.:. . ::.: .:.::::. .: KIAA16 RKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRS------SQSF 870 880 890 900 910 1060 1070 1080 1090 1100 1110 FLJ002 TKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPA .. : :::. .:.. :::::::. : ..:. ::: : :. .:.::. KIAA16 VQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGC 920 930 940 950 960 970 1120 FLJ002 GQVRVCRRPTMPS KIAA16 PFPAKLDLQQGQNLLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL 980 990 1000 1010 1020 1030 >>KIAA0083 ( 1077 res) ha03631 (1077 aa) initn: 298 init1: 111 opt: 198 Z-score: 187.2 bits: 46.4 E(): 3.1e-05 Smith-Waterman score: 305; 27.221% identity (56.734% similar) in 349 aa overlap (786-1109:729-1057) 760 770 780 790 800 810 FLJ002 ITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCT :..... :.. : :: ..:. : KIAA00 VDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVAT 700 710 720 730 740 750 820 830 840 850 860 870 FLJ002 CSCAASA----SLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVV .: . : ::.: .::::.. ..: : :: : ... ::.:::.:: :.: KIAA00 -TCMGINHPIFSRKIFDF--CIVDEASQISQPICLGPLF-F--SRRFVLVGDHQQLPPLV 760 770 780 790 800 810 880 890 900 910 920 FLJ002 KNERLQNLGLDRSLFERYHEDAH---MLDTQYRMHEGICAFPSVAFYKSKLKTWQ----- :.. . ::...:::.: ... .: .::::. : .. . :..::. . KIAA00 LNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVAN 820 830 840 850 860 870 930 940 950 960 970 FLJ002 ---GLRRPPSVLG----HAGKESCPVIFGHVQGHERSLLVSTD------EGNENSKANLE .::. .: .: . : ..: . .. ...:: . .... .:. KIAA00 AVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVT 880 890 900 910 920 930 980 990 1000 1010 1020 1030 FLJ002 EVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSE :. .: .:. . . :.::....:: : . :. : : .:. : :... : :: . KIAA00 EAKLIVFLTS-IFVKAGCSPSDIGIIAPYRQQLKIINDLLAR-SIGMVEVNTVDKYQGRD 940 950 960 970 980 990 1040 1050 1060 1070 1080 1090 FLJ002 WRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLR :::: ::. . . . :.: . .:::.:::.. : :.: : KIAA00 KSIVLVSFVRSNKDGTVGEL-LKDWRR-----------LNVAITRAKHKLILLGCVPSLN 1000 1010 1020 1030 1100 1110 1120 FLJ002 CCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS : : ..::. .... .. KIAA00 CYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQRE 1040 1050 1060 1070 >>KIAA0221 ( 1151 res) ha02799 (1151 aa) initn: 601 init1: 143 opt: 188 Z-score: 177.4 bits: 44.7 E(): 0.00011 Smith-Waterman score: 645; 27.316% identity (52.732% similar) in 842 aa overlap (309-1115:227-940) 280 290 300 310 320 330 FLJ002 GSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAA--ALIQEKGEASQRRELVQ .: : : : :. .: . . ..:: . :.: KIAA02 PLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQ 200 210 220 230 240 250 340 350 360 370 380 390 FLJ002 VQRSHCGHFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGD .: . .... : . :... :. : . : .:: : : :: .:.:: KIAA02 -DRCFLSWLVKIPSE---QEQLRARQITAQQINKL---EELWKENP--SATLEDLEKPG- 260 270 280 290 300 400 410 420 430 440 FLJ002 CFSGRVYRAPRD---RYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWE---- : . :. ::.:. .: .. :. :: : ..: : ....: :. KIAA02 -----VDEEPQHVLLRYEDAYQYQNIFGPLVKLE-ADYDKKLKESQTQDNITVRWDLGLN 310 320 330 340 350 360 450 460 470 480 490 500 FLJ002 ASRTPQGQL----QGAFRLEAAFLEENCADINF-SCCYLCIRLEGLPAPTASPRPGPSSL .: : .: : .:. :. . . .:.: .: :: . .. KIAA02 KKRIAYFTLPKTDSGNEDLVIIWLR----DMRLMQGDEICLRYKGDLAPLWK------GI 370 380 390 400 410 510 520 530 540 550 560 FLJ002 GPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLF : ..: : .: .:. : .: .: :: . : KIAA02 GHVIKV-PDNY----------------GDEIAIELR-----SSVG---APVEVTHN---F 420 430 440 570 580 590 600 610 FLJ002 TVELLPKQLPDLRKEEAVR--GLEEAS--PLVTSIALGRPVPQPLCRV-IPSRFLERQTY :... :. : . :.. ...:.: . ::. : . . . .:.:: . KIAA02 QVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLPKRFTAQ--- 450 460 470 480 490 620 630 640 650 660 670 FLJ002 NIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGP : :: :: ::. .:..:...::::::::::... ::. . . : .:: KIAA02 ----GLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLAR------QGNGP 500 510 520 530 540 680 690 700 710 720 730 FLJ002 PRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKL .: :.::: .:: :. . .. :: .:. ... :: . :: KIAA02 -----------VLVCAPSNIAVDQLTEKI-HQTGLKVVRLCAKSREAIDSPVSF------ 550 560 570 580 590 740 750 760 770 780 790 FLJ002 LRKSPREGRPNQSLRSITLHHRIRQAPN-PYSSEIKAFDTRLQRGELFSREDLVWYKKVL ..::..::. . : .... . . . ::: : : :. . KIAA02 ----------------LALHNQIRNMDSMPELQKLQQL--KDETGEL-SSADEKRYRALK 600 610 620 630 800 810 820 830 840 850 FLJ002 WEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEKV :.. : .:: ::: :.. : .. :.::.::. .::::: ..:.: :... KIAA02 RTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVL--GAKQL 640 650 660 670 680 690 860 870 880 890 900 910 FLJ002 VLLGDHKQLRPVVKNERLQNLGLDRSLFERY---HEDAHMLDTQYRMHEGICAFPSVAFY .:.::: :: ::: .. . ::..::::: :..::::: .. :::: :: KIAA02 ILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFY 700 710 720 730 740 750 920 930 940 950 960 970 FLJ002 KSKLKTWQGLRRPPSVLG----HAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEE ...:. .:. : . . . :..: .::.:. .:. :.. ::.:. KIAA02 EGSLQ--NGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYLNRTEAANVEK 760 770 780 790 800 980 990 1000 1010 1020 FLJ002 VAEVVRITKQLTLGRTVEPQDIAVLTPYNAQAS------EISKALRREGIAGVAVSSITK .. :: : : ..:..:...:::..: : ..: .:. . : ..:. KIAA02 IT-----TKLLKAG--AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDA 810 820 830 840 850 860 1030 1040 1050 1060 1070 1080 FLJ002 SQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGD :: : ....: :.... : .::. :: ..:::.:::. :. ..:. KIAA02 FQGREKDFIILS----CVRANEHQG---------IGFLNDPRRLNVALTRARYGVIIVGN 870 880 890 900 1090 1100 1110 1120 FLJ002 HLLLRCCPLWRSLLDFCEAQQTLV--PAGQVRVCRRPTMPS : ::: ::.. . :..:: : ...: KIAA02 PKALSKQPLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMY 910 920 930 940 950 960 KIAA02 DAREAIIPGSVYDRSSQGRPSSMYFQTHDQIGMISAGPSHVAAMNIPIPFNLVMPPMPPP 970 980 990 1000 1010 1020 >>KIAA1008 ( 935 res) hh04776s1 (935 aa) initn: 141 init1: 108 opt: 175 Z-score: 166.0 bits: 42.3 E(): 0.00048 Smith-Waterman score: 175; 24.375% identity (54.375% similar) in 160 aa overlap (57-211:662-820) 30 40 50 60 70 80 FLJ002 LRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAAR : : .:: . ..:.. .. .. . KIAA10 ELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIK 640 650 660 670 680 690 90 100 110 120 130 140 FLJ002 TQDYEQMVDLVTTDD--MHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYT :. ..... . . :.: : : .: :. : ... ::.: :: KIAA10 TDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS-GMDNDFHHYGLASPIYT 700 710 720 730 740 750 150 160 170 180 190 200 FLJ002 WATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQAFSLQHALAQSYQRRARS ::::::: ::...: . .:.: . : . .:. ....: .:: :: . . KIAA10 HFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVA 760 770 780 790 800 810 210 220 230 240 250 260 FLJ002 LHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALA .: . .:.. KIAA10 FHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPS 820 830 840 850 860 870 >>KIAA1955 ( 947 res) fk07007 (947 aa) initn: 113 init1: 113 opt: 170 Z-score: 161.2 bits: 41.4 E(): 0.00089 Smith-Waterman score: 170; 28.058% identity (59.712% similar) in 139 aa overlap (83-209:622-757) 60 70 80 90 100 110 FLJ002 LHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAG : :.. . ..: : ...: : :.. KIAA19 SFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLL 600 610 620 630 640 650 120 130 140 150 160 FLJ002 RDL-RKALERSAF---GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLAL :.. .:. . . : :: ... ::.: .: :: ::::::: :.:..: .. :. KIAA19 RSMATQAMSNALYFSTGSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAI 660 670 680 690 700 170 180 190 200 210 220 FLJ002 GHG------GSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVV .. :. .: .:.. ::. .. .. :: :... : . .: KIAA19 SKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCI 710 720 730 740 750 760 230 240 250 260 270 280 FLJ002 DVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGS KIAA19 SDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITS 770 780 790 800 810 820 >>FLJ00247 ( 925 res) sj08552 (925 aa) initn: 209 init1: 91 opt: 144 Z-score: 136.5 bits: 36.8 E(): 0.021 Smith-Waterman score: 258; 25.146% identity (48.928% similar) in 513 aa overlap (535-1002:432-861) 510 520 530 540 550 FLJ002 GPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEV------- :: : . :::.. ...: FLJ002 LTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSR 410 420 430 440 450 460 560 570 580 590 600 610 FLJ002 LRPGTLFTVELLPKQLPDLRKEEAVRGLEEAS-----PLVTSIALGRPVPQPLCRVIPSR . : : :.. .. : :: .. :.:: .. :.. .: : :: : . . FLJ002 FVDGLTFKVNFTFNRQP-LRVQH--RALELTGRWLLWPMLFPVA-PRDVPL-LPSDVKLK 470 480 490 500 510 620 630 640 650 660 670 FLJ002 FLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQE . .:. . : ..:. ..... . :. .: ::::::::.. .. . . FLJ002 LYDRSLESNP---EQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------K 520 530 540 550 560 680 690 700 710 720 730 FLJ002 QVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVP :: :.: :: :.:::...:.: : :..: : .: : : FLJ002 QVV--------KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLA-----P-- 570 580 590 600 740 750 760 770 780 790 FLJ002 RVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLV :: . : :.. .: . .:.. .:: FLJ002 ---SRDI-RMVPEDIKPCCN-----------------------WDAK--KGEY------- 610 620 630 800 810 820 830 840 FLJ002 WYKKVLWEARKFELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPL .. :.: .:....:.. : :. ::.. : .:..:::: :::.:. . FLJ002 -----VFPAKK-KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAI 640 650 660 670 680 850 860 870 880 890 FLJ002 VQFPQAE-------KVVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHM . . ... ..:: :: .:: ::... :. :: ::.:: :.. FLJ002 AGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDG 690 700 710 720 730 740 900 910 920 930 940 FLJ002 LDTQ--------YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFG : : :: : : .:. .:...:.. . :: ... :.:: FLJ002 YDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFH 750 760 770 780 790 800 950 960 970 980 990 FLJ002 HVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTL-----GRT-VEPQDIAVLTPY :.:... ::: : : ::.: :. : : :.. . :....:..:: FLJ002 GVMGKDER------EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPY 810 820 830 840 850 1000 1010 1020 1030 1040 1050 FLJ002 NAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF : FLJ002 RKQVRSSVTSKGGAPPPDGTSLISRPLGRGSRSLGLCWLRISEEHQGQLPPPFVPQLPGL 860 870 880 890 900 910 >>KIAA1404 ( 1925 res) eg01672 (1925 aa) initn: 281 init1: 138 opt: 138 Z-score: 127.4 bits: 36.2 E(): 0.067 Smith-Waterman score: 297; 27.707% identity (55.732% similar) in 314 aa overlap (810-1117:986-1270) 780 790 800 810 820 830 FLJ002 LQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASAS--LKILDVRQILVDEA .:. : . ::. :. .. : ..:.:: KIAA14 ILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEA 960 970 980 990 1000 1010 840 850 860 870 880 890 FLJ002 GMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERL-QNLGLDRSLFERYHE---DA . . : .:. : . ....:.:::.:::: .. : .:..:. ::::: . KIAA14 AEVLEAHTIATLSK--ACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPF 1020 1030 1040 1050 1060 1070 900 910 920 930 940 950 FLJ002 HMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERS :. :.:: : : .: . . .: :. :::: . .. . :. . KIAA14 VRLNYQHRM----C--PEIARLLTP-HIYQDLENHPSVLKYEKIKGVSSNLFFVEHNFPE 1080 1090 1100 1110 1120 960 970 980 990 1000 1010 FLJ002 LLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRRE . .:: .:. : .:. ::.. : . : . :..:..:: :..: . : . . KIAA14 QEI--QEG--KSHQNQHEAHFVVELCKYF-LCQEYLPSQITILTTYTGQLFCLRKLMPAK 1130 1140 1150 1160 1170 1180 1020 1030 1040 1050 1060 1070 FLJ002 GIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAV .::: : . : :: : .:.: ::. .. .::. :.. ::. KIAA14 TFAGVRVHVVDKYQGEENDIILLSLVRSNQEGK-------------VGFLQISNRICVAL 1190 1200 1210 1220 1080 1090 1100 1110 1120 FLJ002 TRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS .::..:. ::. .: ::: ... . .. . : ..:.: KIAA14 SRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQIGP--MLRLCCQNHPETHTLVSKASD 1230 1240 1250 1260 1270 1280 KIAA14 FQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMKPCQKVICQEGHRCPLVCFQ 1290 1300 1310 1320 1330 1340 >>FLJ00327 ( 266 res) sj02293 (266 aa) initn: 113 init1: 113 opt: 125 Z-score: 124.1 bits: 32.7 E(): 0.1 Smith-Waterman score: 129; 28.313% identity (53.012% similar) in 166 aa overlap (66-212:61-215) 40 50 60 70 80 90 FLJ002 QQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQFAARTQDYEQM-- ::.::. :..: :.: .:: FLJ003 VEEFMLLANMAVAHKIHRAFPEQALLRRHPPPQTRM--LSDL---VEFC------DQMGL 40 50 60 70 100 110 120 130 FLJ002 -VDLVTTDDMHPFLAPAGRDLRKALERSAF--GRCARGHQQ-------------QGGHYS ::. .. .. :. . : . .: :. . :.: :. : ::. FLJ003 PVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSGLLQDPAQFRHYA 80 90 100 110 120 130 140 150 160 170 180 190 FLJ002 LQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD-IDGLCQAFSLQHALAQSYQ :.: :: ::::::. ::...: . :::. : : .. . . .. .. : FLJ003 LNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADHCNDRRMASKRVQ 140 150 160 170 180 190 200 210 220 230 240 250 FLJ002 RRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEH . . :: .:: .:..: FLJ003 ELSTSLFFAVLVKVSPPAWCPSPPSGSRPSWAPAHQEASRSPGQCQEVPWLQHCPCRRVA 200 210 220 230 240 250 1124 residues in 1 query sequences 2209870 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:46:18 2009 done: Fri Feb 27 10:46:19 2009 Total Scan time: 0.880 Total Display time: 0.400 Function used was FASTA [version 34.26.5 April 26, 2007]