# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sj08552.fasta.huge -Q ../query/FLJ00247.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00247, 925 aa vs ./tmplib.10216 library 2210069 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 4.1357+/-0.00417; mu= 23.3331+/- 0.281 mean_var=100.3775+/-22.426, 0's: 0 Z-trim: 8 B-trim: 4 in 1/39 Lambda= 0.128014 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 39, opt: 27, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA1631 ( 1032 res) fh15959s1 (1032) 5352 999.5 0 KIAA0054 ( 1943 res) ha00503s1 (1943) 352 76.5 4.1e-14 KIAA0221 ( 1151 res) ha02799 (1151) 257 58.6 5.9e-09 FLJ00244 ( 1124 res) sj07756 (1124) 144 37.7 0.011 KIAA1769 ( 2114 res) af00171 (2114) 144 38.2 0.016 FLJ00400 ( 782 res) sj07486 ( 782) 121 33.2 0.17 KIAA1618 ( 1415 res) fj14314 (1415) 121 33.6 0.24 KIAA0944 ( 4031 res) hj04408s1 (4031) 122 34.5 0.37 KIAA0560 ( 1521 res) hj07625 (1521) 114 32.4 0.61 KIAA1433 ( 652 res) hh05535 ( 652) 103 29.8 1.6 KIAA0083 ( 1077 res) ha03631 (1077) 102 30.0 2.4 FLJ00251 ( 1007 res) sj08895 (1007) 98 29.2 3.8 KIAA1438 ( 1075 res) hk07374s1 (1075) 98 29.2 3.9 KIAA0633 ( 1316 res) hj02892 (1316) 98 29.4 4.4 KIAA1142 ( 467 res) hh05864 ( 467) 93 27.7 4.8 KIAA1070 ( 826 res) hj05602 ( 826) 93 28.1 6.5 KIAA1043 ( 2126 res) af02720 (2126) 95 29.1 8.3 KIAA0571 ( 683 res) hh02388 ( 683) 90 27.4 8.6 KIAA1470 ( 564 res) fj01953 ( 564) 89 27.1 8.8 KIAA0325 ( 4658 res) hg00575y2 (4658) 96 29.8 11 KIAA0771 ( 948 res) hk05113 ( 948) 88 27.3 13 KIAA1517 ( 998 res) fh11426(revised) ( 998) 88 27.3 14 KIAA1870 ( 832 res) hh05136b ( 832) 87 27.0 14 KIAA0089 ( 411 res) ha03662 ( 411) 84 26.0 14 KIAA0625 ( 2663 res) hg04796s1 (2663) 91 28.5 16 KIAA1758 ( 1662 res) fh20539(revised) (1662) 89 27.8 16 KIAA0619 ( 1428 res) hg04117 (1428) 88 27.6 16 KIAA1083 ( 584 res) hj07423 ( 584) 84 26.2 17 FLJ00072 ( 204 res) as00072 ( 204) 79 24.6 19 FLJ00089 ( 349 res) as00089 ( 349) 81 25.3 19 KIAA1997 ( 1685 res) bj00195y1 (1685) 87 27.5 20 KIAA2011 ( 1091 res) pj02017 (1091) 85 26.8 21 KIAA1852 ( 948 res) fj01514 ( 948) 83 26.4 25 KIAA0348 ( 1443 res) hg01551(revised) (1443) 84 26.8 27 KIAA0979 ( 1483 res) hj07056s1 (1483) 84 26.8 28 KIAA0278 ( 460 res) ha06634 ( 460) 79 25.1 28 KIAA0582 ( 760 res) fh15957 ( 760) 81 25.8 29 FLJ00417 ( 600 res) sj06336 ( 600) 80 25.5 29 KIAA0608 ( 775 res) hh00889b ( 775) 81 25.9 29 KIAA0121 ( 312 res) fk13569 ( 312) 77 24.5 30 KIAA0269 ( 567 res) ha06751 ( 567) 79 25.3 32 KIAA1110 ( 740 res) hh04831b(revised) ( 740) 80 25.6 32 KIAA1591 ( 1018 res) fj09118 (1018) 81 26.0 33 KIAA1278 ( 1311 res) hg03689(revised) (1311) 82 26.4 34 KIAA1715 ( 429 res) hh02382 ( 429) 77 24.7 35 FLJ00175 ( 1516 res) sj00758 (1516) 82 26.5 36 KIAA1987 ( 357 res) fk04103 ( 357) 76 24.4 36 FLJ00135 ( 597 res) sh02493 ( 597) 78 25.1 37 FLJ00350 ( 601 res) sg00019 ( 601) 78 25.1 37 FLJ00055 ( 977 res) as00055 ( 977) 80 25.8 37 >>KIAA1631 ( 1032 res) fh15959s1 (1032 aa) initn: 5352 init1: 5352 opt: 5352 Z-score: 5340.0 bits: 999.5 E(): 0 Smith-Waterman score: 5352; 100.000% identity (100.000% similar) in 792 aa overlap (71-862:75-866) 50 60 70 80 90 100 FLJ002 CFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYGMKIANLAYVTKTRVR :::::::::::::::::::::::::::::: KIAA16 RVTLRCPFPPAALPPSSPAFPHFPVSSASGSFGTPAPGFSSMLYGMKIANLAYVTKTRVR 50 60 70 80 90 100 110 120 130 140 150 160 FLJ002 FFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHGKHGVDVEVQGPHEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 FFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHGKHGVDVEVQGPHEAR 110 120 130 140 150 160 170 180 190 200 210 220 FLJ002 DGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFYNEDQELPCPLGPGEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 DGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFYNEDQELPCPLGPGEC 170 180 190 200 210 220 230 240 250 260 270 280 FLJ002 YELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAAVAHSPLAAQLKPMTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 YELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAAVAHSPLAAQLKPMTP 230 240 250 260 270 280 290 300 310 320 330 340 FLJ002 FKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRLRQLLPMLLQGTSIFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 FKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRLRQLLPMLLQGTSIFT 290 300 310 320 330 340 350 360 370 380 390 400 FLJ002 APKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDPVDQNPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 APKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDPVDQNPR 350 360 370 380 390 400 410 420 430 440 450 460 FLJ002 LLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 LLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLS 410 420 430 440 450 460 470 480 490 500 510 520 FLJ002 RFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKLKLYDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 RFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKLKLYDR 470 480 490 500 510 520 530 540 550 560 570 580 FLJ002 SLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 SLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAP 530 540 550 560 570 580 590 600 610 620 630 640 FLJ002 SNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 SNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQE 590 600 610 620 630 640 650 660 670 680 690 700 FLJ002 YRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 YRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQL 650 660 670 680 690 700 710 720 730 740 750 760 FLJ002 VLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 VLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSH 710 720 730 740 750 760 770 780 790 800 810 820 FLJ002 PTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: KIAA16 PTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFF 770 780 790 800 810 820 830 840 850 860 870 880 FLJ002 NPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVRSSVTSKGGAPPPDGTSL :::::::::::::::::::::::::::::::::::::::::: KIAA16 NPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLD 830 840 850 860 870 880 890 900 910 920 FLJ002 ISRPLGRGSRSLGLCWLRISEEHQGQLPPPFVPQLPGLLPGSLLH KIAA16 DIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKAL 890 900 910 920 930 940 >>KIAA0054 ( 1943 res) ha00503s1 (1943 aa) initn: 420 init1: 100 opt: 352 Z-score: 346.8 bits: 76.5 E(): 4.1e-14 Smith-Waterman score: 492; 29.455% identity (61.139% similar) in 404 aa overlap (469-862:591-961) 440 450 460 470 480 490 FLJ002 KGFVHKVELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALE-LTGRWLLWPM ...: .:: :: .: ::. . .:.: KIAA00 EEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPD 570 580 590 600 610 620 500 510 520 530 540 550 FLJ002 LFPVAPRDVPLLPSDVKLKLYDRSLES--NPEQLQAMRHIVTGTT-RPAPYIIFGPPGTG . ..: .: :. . .:..:. : .: .:. :.: . . : .:.:: ::: KIAA00 I-SMTPT-IPWSPN----RQWDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTG 630 640 650 660 670 560 570 580 590 600 FLJ002 KTVTLVEAIKQVVKHLPKAHILACAPSNSGADL-----LCQRLRVHLPSS-IYRLLAPSR :: ::..:.:..... ...:: :. :::.::: : ... :.. :. .: KIAA00 KTFTLAQAVKHILQQ-QETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNR 680 690 700 710 720 730 610 620 630 640 650 660 FLJ002 DIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIF .. : .. : .. .. . .: :. . ..::...:: :. : . .. ::::. KIAA00 WVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHIL 740 750 760 770 780 790 670 680 690 700 710 720 FLJ002 IDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLL .:::.. :: :... .: . ...: ..::::: ::.: . : ......: ::: KIAA00 LDEAAQAMECETIMPLA--LATQNT-----RIVLAGDHMQLSPFVYSEFARERNLHVSLL 800 810 820 830 840 730 740 750 760 770 780 FLJ002 ERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERF .:: :.. : . ... : .::::: .:.. ..:.:::.:.: . .. : KIAA00 DRL------YEHYPAEFPCRIL--LCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDF 850 860 870 880 890 790 800 810 820 830 840 FLJ002 CRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLS .:. : . :.: .: :: .:.: :. :. .. : . . ..:. KIAA00 ----------YPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRR-KWPVAWGKLD 900 910 920 930 940 850 860 870 880 890 900 FLJ002 PRSVGVISPYRKQVRSSVTSKGGAPPPDGTSLISRPLGRGSRSLGLCWLRISEEHQGQLP :.::..:: :: KIAA00 DGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQ 950 960 970 980 990 1000 >>KIAA0221 ( 1151 res) ha02799 (1151 aa) initn: 405 init1: 146 opt: 257 Z-score: 254.1 bits: 58.6 E(): 5.9e-09 Smith-Waterman score: 391; 29.396% identity (54.396% similar) in 364 aa overlap (525-861:505-832) 500 510 520 530 540 550 FLJ002 WPMLFPVAPRDVPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTG : :. :.. .. :: .: :::::: KIAA02 YHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL---QRPLS-LIQGPPGTG 480 490 500 510 520 530 560 570 580 590 FLJ002 KTVTLVEAIKQVVKHLPKAHILACAPSNSGADLL--------------CQRLR--VHLPS :::: . . ..... .. .:.::::: ..: : : . : . : KIAA02 KTVTSATIVYHLARQ-GNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPV 540 550 560 570 580 600 610 620 630 640 650 FLJ002 SIYRLLAPSRDIRMVPE-----DIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGR :. : :.. .:: ..: . .. : . : :. : ..:... . KIAA02 SFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVICCT 590 600 610 620 630 640 660 670 680 690 700 710 FLJ002 LVSAQFP---IDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLG :.: : .: :.:::. . ::: .: . .. .: ::.:.:: ::: KIAA02 CVGAGDPRLAKMQFRSILIDESTQATEPECMVPV--VLGAK-------QLILVGDHCQLG 650 660 670 680 690 700 720 730 740 750 760 770 FLJ002 PVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQL ::. . : ::. ::.:::.. : : .: .:: ::.. .:... KIAA02 PVVMCKKAAKAGLSQSLFERLVVL---------GIRP---IRLQVQYRMHPALSAFPSNI 710 720 730 740 780 790 800 810 820 FLJ002 YYEGELQACADVVDRER--F-CRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAAT .::: :: . ..:: . : .: :. :..:. ..:..: ... :..: :::. KIAA02 FYEGSLQNGVTAADRVKKGFDFQW---PQPDKPMFFYVTQGQEEIASSGTSYLNRTEAAN 750 760 770 780 790 800 830 840 850 860 870 880 FLJ002 VTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVRSSVTSKGGAPPPDGTSLISRPLGR : . :: :: .: ..:.:.::. : KIAA02 VEKITTKLL-------KAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIAS 810 820 830 840 850 890 900 910 920 FLJ002 GSRSLGLCWLRISEEHQGQLPPPFVPQLPGLLPGSLLH KIAA02 VDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLW 860 870 880 890 900 910 >>FLJ00244 ( 1124 res) sj07756 (1124 aa) initn: 209 init1: 91 opt: 144 Z-score: 141.4 bits: 37.7 E(): 0.011 Smith-Waterman score: 258; 24.561% identity (48.733% similar) in 513 aa overlap (432-861:535-1002) 410 420 430 440 450 460 FLJ002 LTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSR :: : . :::.. ...: FLJ002 GPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEV------- 510 520 530 540 550 470 480 490 500 510 FLJ002 FVDGLTFKVNFTFNRQP-LRVQH--RALELTGRWLLWPMLFPVA-PRDVPL-LPSDVKLK . : : :.. .. : :: .. :.:: .. :.. .: : :: : . . FLJ002 LRPGTLFTVELLPKQLPDLRKEEAVRGLEEAS-----PLVTSIALGRPVPQPLCRVIPSR 560 570 580 590 600 610 520 530 540 550 560 FLJ002 LYDRSLESNP---EQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------K . .:. . : ..:. ..... . :. .: ::::::::.. .. . . FLJ002 FLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQE 620 630 640 650 660 670 570 580 590 600 FLJ002 QVV--------KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD---- :: :.: :: :.:::...:.: : :..: : .: : . . FLJ002 QVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVP 680 690 700 710 720 730 610 620 630 FLJ002 -------IRMVPEDIKPCCN-----------------------WDAK--KGEY------- .: :.. .: . .:.. .:: FLJ002 RVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLV 740 750 760 770 780 790 640 650 660 670 680 FLJ002 -----VFPAKK-KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAI .. :.: .:....:.. : :. ::.. : .:..:::: :::.:. . FLJ002 WYKKVLWEARKFELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPL 800 810 820 830 840 690 700 710 720 730 740 FLJ002 AGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDG . . ... ..:: :: .:: ::... :. :: ::.:: :.. FLJ002 VQFPQAE-------KVVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHM 850 860 870 880 890 750 760 770 780 790 800 FLJ002 YDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFH : : :: : : .:. .:...:.. . :: ... :.:: FLJ002 LDTQ--------YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFG 900 910 920 930 940 810 820 830 840 850 FLJ002 GVMGKDER------EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPY :.:... ::: : : ::.: :. : : :.. . :....:..:: FLJ002 HVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTL-----GRT-VEPQDIAVLTPY 950 960 970 980 990 860 870 880 890 900 910 FLJ002 RKQVRSSVTSKGGAPPPDGTSLISRPLGRGSRSLGLCWLRISEEHQGQLPPPFVPQLPGL : FLJ002 NAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF 1000 1010 1020 1030 1040 1050 >>KIAA1769 ( 2114 res) af00171 (2114 aa) initn: 209 init1: 91 opt: 144 Z-score: 138.8 bits: 38.2 E(): 0.016 Smith-Waterman score: 259; 24.237% identity (48.115% similar) in 557 aa overlap (389-861:1491-1992) 360 370 380 390 400 410 FLJ002 RNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDP-VDQNPRLLTLEVPGVTESRPSVL : . : .. .: : . : ::. . KIAA17 ENCADINFSCCYLCIRLEGLLAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTEDWDQER 1470 1480 1490 1500 1510 1520 420 430 440 450 460 470 FLJ002 RGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQ :.:. :: : . :::.. ...: . : : :.. .. KIAA17 RADR----------QEAPRRVHLFVHHMGMEKVPEEV-------LRPGTLFTVELLPKQL 1530 1540 1550 1560 480 490 500 510 520 FLJ002 P-LRVQH--RALELTGRWLLWPMLFPVA-PRDVPL-LPSDVKLKLYDRSLESNP---EQL : :: .. :.:: .. :.. .: : :: : . .. .:. . : ..: KIAA17 PDLRKEEAVRGLEEAS-----PLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKL 1570 1580 1590 1600 1610 530 540 550 560 570 FLJ002 QAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV--------KHLPK . ..... . :. .: ::::::::.. .. . .:: :.: KIAA17 NPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGG 1620 1630 1640 1650 1660 1670 580 590 600 610 FLJ002 AHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMVPEDIK :: :.:::...:.: : :..: : .: : . . .: :.. . KIAA17 PCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGR 1680 1690 1700 1710 1720 1730 620 630 640 FLJ002 PCCN-----------------------WDAK--KGEY------------VFPAKK-KLQE : . .:.. .:: .. :.: .:.. KIAA17 PNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDR 1740 1750 1760 1770 1780 1790 650 660 670 680 690 700 FLJ002 YRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQL ..:.. : :. ::.. : .:..:::: :::.:. .. . ... .. KIAA17 HEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAE-------KV 1800 1810 1820 1830 1840 710 720 730 740 750 760 FLJ002 VLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSH :: :: .:: ::... :. :: ::.:: :.. : : :: : KIAA17 VLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ--------YRMH 1850 1860 1870 1880 1890 770 780 790 800 810 FLJ002 PTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER------EG : .:. .:...:.. . :: ... :.:: :.:... :: KIAA17 EGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLVSTDEG 1900 1910 1920 1930 1940 1950 820 830 840 850 860 870 FLJ002 NSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVRSSVTSKGGAPP : : : ::.: :. : : :.. . :....:..:: : KIAA17 NENSKANLEEVAEVVRITKQLTL-----GRT-VEPQDIAVLTPYNAQASEISKALRREGI 1960 1970 1980 1990 2000 880 890 900 910 920 FLJ002 PDGTSLISRPLGRGSRSLGLCWLRISEEHQGQLPPPFVPQLPGLLPGSLLH KIAA17 AGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTR 2010 2020 2030 2040 2050 2060 >>FLJ00400 ( 782 res) sj07486 (782 aa) initn: 103 init1: 62 opt: 121 Z-score: 120.0 bits: 33.2 E(): 0.17 Smith-Waterman score: 121; 28.926% identity (61.157% similar) in 121 aa overlap (324-441:132-245) 300 310 320 330 340 350 FLJ002 NRIEEGERPDRAKGYDLELSMALGTYYPPPRLRQLLPMLLQGTSIFTAPKEIAEIKAQLE :::. : .: ... . . :: . . FLJ004 KRLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLWEGA--LYEIGGLFG 110 120 130 140 150 360 370 380 390 400 410 FLJ002 TALKWRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTW-DPVDQNPRL-LTLEVPGVTE :.. :.: . ::.:: :. :.. . .. .:..: : : .: : :::. :: . FLJ004 TGI--RSYFTFLRFLLLLNLLSL---LLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQ 160 170 180 190 200 210 420 430 440 450 460 470 FLJ002 SRPSVLR-GDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSRFVDGLTFKV : :.::: ..:. .:.... . . : .. FLJ004 SPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFC 220 230 240 250 260 270 480 490 500 510 520 530 FLJ002 NFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKLKLYDRSLESNPEQLQ FLJ004 GTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEG 280 290 300 310 320 330 >>KIAA1618 ( 1415 res) fj14314 (1415 aa) initn: 99 init1: 62 opt: 121 Z-score: 117.5 bits: 33.6 E(): 0.24 Smith-Waterman score: 132; 25.166% identity (50.662% similar) in 302 aa overlap (292-578:375-656) 270 280 290 300 310 320 FLJ002 FLAAVAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYP : :.: .: : : .:: .. .. : . . KIAA16 LFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFS 350 360 370 380 390 400 330 340 350 360 370 FLJ002 ------PPRLRQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQ : ... .. : .. : : : .::: : :..:. ::: : ::.. KIAA16 ILQTWDTINLNSFFTQFEQFCFVLQQPM-IYEGQAQLWTDLQYREKEVKRYLWQHLKK-- 410 420 430 440 450 460 380 390 400 410 420 430 FLJ002 MEHDIRHYDLESVPMTWDPVDQNPR--LLT-LEVPGVTESRPSVLRG--DHLFALLSSET : . : .:. . ::: : : : : : :.:. .:.: : : ::.:.. KIAA16 --HVVPLPDGKSTDFL--PVDCPVRSKLKTGLIVLFVVEKIELLLEGSLDWLCHLLTSDA 470 480 490 500 510 440 450 460 470 480 490 FLJ002 HQEDPITYKGFVHKVELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTG . : . .. . : . . . . ..: .: .: :. .. : : : .::. KIAA16 SSPDEF-HRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTW---LGALP--VLHCCMELAP 520 530 540 550 560 570 500 510 520 530 540 FLJ002 RWL-LWPMLFPVAPRDVPLLPSDVKLKLYDRSLESNPEQLQAMR---HIVTGTTRPAPYI : : . :.:. .... . ... .. :: :: :... .: KIAA16 RHKDAWRQ-----PEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLS-IDEPLFRS 580 590 600 610 620 550 560 570 580 590 600 FLJ002 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP :. .. : .: . . . ..: :::: : KIAA16 WFSLLPLSHLVMYMENFIEHLGRFP-AHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQN 630 640 650 660 670 680 610 620 630 640 650 660 FLJ002 SRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTH KIAA16 ILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMI 690 700 710 720 730 740 >>KIAA0944 ( 4031 res) hj04408s1 (4031 aa) initn: 96 init1: 71 opt: 122 Z-score: 114.2 bits: 34.5 E(): 0.37 Smith-Waterman score: 143; 18.763% identity (51.134% similar) in 485 aa overlap (317-783:1755-2194) 290 300 310 320 330 340 FLJ002 TGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRLRQLLPMLLQGTSIFTAPKEIA : : :.. :..:. .... : .. KIAA09 GEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLL--PASVS 1730 1740 1750 1760 1770 1780 350 360 370 380 390 400 FLJ002 EIKAQLETALKWRNYEVKLRLLL-HLEELQMEHDIRHYDLESVPMTWDP-VDQNPRLLTL :. .. .: : :..... : .::. : ..:. : .:. . : KIAA09 VIQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNL--VRSLMNLIDCFMDDFADEVKL 1790 1800 1810 1820 1830 1840 410 420 430 440 450 FLJ002 EVPGVTESRPSVLRGDHLFALLSS---ETHQEDPITYKGFVHKVEL----DRVKLSFSMS . . :. :.:.: ::.:. : ..: . .. ..... ::.. .:... KIAA09 KERNDRETY-SLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQ 1850 1860 1870 1880 1890 460 470 480 490 500 510 FLJ002 LLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKLKL .. ... .. : : .. . . . : :.: : . ...: .:.:: . KIAA09 SGTEQTSSKALTVPFP-EKGTIYDYQFVTEGIGKWEPWIKKL----KEAPPIPKDV---M 1900 1910 1920 1930 1940 1950 520 530 540 550 560 570 FLJ002 YDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVE-AIKQVVKHLPKAHIL ... . . . .. . ::. : :. :: ::::.: ... ..:. :.. : .. KIAA09 FNEIIVPTLDTIRYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLI 1960 1970 1980 1990 2000 2010 580 590 600 610 620 630 FLJ002 ACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKKGEYVFPAKK . ....:. ...: : : . .:: . : : KIAA09 NFSAQTTAAQ--------------------TQNIVMSKLDKR-------RKGVFGPPLGK 2020 2030 2040 640 650 660 670 680 690 FLJ002 KLQEYRVLITTLITAGRLV-SAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD .. :.. . .: : .:: ::. . . . . .. :.. .. .. . : KIAA09 RMV---VFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2050 2060 2070 2080 2090 2100 700 710 720 730 740 FLJ002 PGG--QLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYN-SLYKKGPDGY---DPQF ::: . : :... . . ...: :... :.::.. . : :: . :. KIAA09 PGGGRNPVTPRYMRHFNIITINEFSDKSM--YTIFSRILTWHLEICYKFPDEFLDLTTQI 2110 2120 2130 2140 2150 750 760 770 780 790 800 FLJ002 ITKLLRNYR-SHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMG .. . :. . ..: : . .: .:. . :. KIAA09 VNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEV 2160 2170 2180 2190 2200 2210 810 820 830 840 850 860 FLJ002 KDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVRSSVTS KIAA09 LRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCD 2220 2230 2240 2250 2260 2270 >>KIAA0560 ( 1521 res) hj07625 (1521 aa) initn: 139 init1: 100 opt: 114 Z-score: 110.3 bits: 32.4 E(): 0.61 Smith-Waterman score: 114; 30.769% identity (69.231% similar) in 65 aa overlap (528-592:842-902) 500 510 520 530 540 550 FLJ002 LFPVAPRDVPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTV :..:.: .: .:. .. :::::::: KIAA05 TLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIR---AGM-QPGLTMVVGPPGTGKTD 820 830 840 850 860 560 570 580 590 600 610 FLJ002 TLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDI . :. :... ...:. . : . ::.. . : ... KIAA05 VAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKD 870 880 890 900 910 920 620 630 640 650 660 670 FLJ002 KPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCME KIAA05 FSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKV 930 940 950 960 970 980 >>KIAA1433 ( 652 res) hh05535 (652 aa) initn: 97 init1: 68 opt: 103 Z-score: 102.8 bits: 29.8 E(): 1.6 Smith-Waterman score: 106; 24.242% identity (51.136% similar) in 264 aa overlap (673-920:363-604) 650 660 670 680 690 700 FLJ002 VLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPE--SLVAIAGLMEVKETGDPGGQL ::: .:: . ... .:.. : . KIAA14 ERTHGSNIAKMTNTGLPGPATPAYSYAKTNGHC-DPEIQTTRELTAGNNVENQVPPREKS 340 350 360 370 380 390 710 720 730 740 750 FLJ002 V-LAGD-PRQLG--PV-LRSPLTQKHGL---GYSLLERLLTYNSLYKKGPDGYDPQFITK : :: . : . : :: ...:. . : : :: . .:: ..: . .: . . KIAA14 VALAQEKPVENGGCPVGIETPVPMPSPLSSSGSSLSPSSTASSSL-TSSPCS-SPVLTKR 400 410 420 430 440 760 770 780 790 800 810 FLJ002 LLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER :: . : : . :. . ...: :..: : .:. :... : KIAA14 LLGSSASSPGYQS-SYQVGINQRFHAA-----RHKFQSQADQDQQA-----SGLQSPPSR 450 460 470 480 490 820 830 840 850 860 FLJ002 EGNSPSFFNPEEAATVT--SYLKLLLAPSSKKGKAR-LSPRSVGVISPYRKQVRSSVTSK . ::.... : .. . ..: .:..: . .:: : . ::. . .... . KIAA14 DL-SPTLIDNSAAKQLARNTVTQVLSRFTSQQGPIKPVSPNSSPFGTDYRN-LANTANPR 500 510 520 530 540 550 870 880 890 900 910 920 FLJ002 GG---APPPDGTSLISRPLGRGSRSLGLCWLRISEEHQGQLPPPFVPQLPGLLPGSLLH : .: : .: ::. : .: : . ..:. :::. :. ::: : KIAA14 GDTSHSPTPGKVSSPLSPLSPGIKS-----PTIPRAERGN-PPPIPPKKPGLTPSPSATT 560 570 580 590 600 610 KIAA14 PLTKTHSQAASLTTAEDLASSCSSNTVVANGKDVELLLPTSS 620 630 640 650 925 residues in 1 query sequences 2210069 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 10:46:56 2009 done: Fri Feb 27 10:46:57 2009 Total Scan time: 0.770 Total Display time: 0.360 Function used was FASTA [version 34.26.5 April 26, 2007]