# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -H -O./tmp/sj09483.fasta.huge -Q ../query/FLJ00419.ptfa ./tmplib.10216 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 FLJ00419, 229 aa vs ./tmplib.10216 library 2210765 residues in 2457 sequences Expectation_n fit: rho(ln(x))= 9.4857+/-0.0072; mu= -9.4944+/- 0.480 mean_var=375.5255+/-84.624, 0's: 0 Z-trim: 15 B-trim: 0 in 0/40 Lambda= 0.066184 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 36, opt: 24, open/ext: -10/-2, width: 16 The best scores are: opt bits E(2457) KIAA0853 ( 967 res) hk06136 ( 967) 321 43.9 3.3e-05 KIAA0670 ( 1286 res) hk02359s1 (1286) 266 38.8 0.0015 KIAA0801 ( 1058 res) hg03949(revised) (1058) 228 35.1 0.016 KIAA0139 ( 1388 res) ha04032 (1388) 226 35.0 0.022 KIAA0138 ( 962 res) ha03743 ( 962) 213 33.6 0.041 KIAA1019 ( 2309 res) fg00188s1 (2309) 218 34.6 0.052 KIAA0687 ( 1175 res) hk02992 (1175) 206 33.0 0.075 KIAA0182 ( 1157 res) ha02329s1 (1157) 204 32.8 0.084 KIAA1172 ( 929 res) hj03919(revised) ( 929) 198 32.2 0.11 KIAA0332 ( 1028 res) hg00939 (1028) 187 31.2 0.24 KIAA1187 ( 813 res) fk03027 ( 813) 184 30.7 0.25 KIAA0224 ( 1256 res) ha04657 (1256) 184 31.0 0.33 KIAA0389 ( 1296 res) hj00061 (1296) 180 30.6 0.44 FLJ00353 ( 1766 res) sh01144 (1766) 177 30.5 0.66 KIAA0642 ( 1329 res) hh02837 (1329) 174 30.1 0.67 KIAA1966 ( 480 res) fh23421 ( 480) 162 28.4 0.78 KIAA0521 ( 1050 res) hg01387 (1050) 169 29.5 0.81 KIAA0887 ( 443 res) hk07788 ( 443) 157 27.8 1 KIAA1064 ( 1315 res) hj05008s1 (1315) 167 29.4 1.1 KIAA1604 ( 937 res) fj10713 ( 937) 162 28.7 1.2 KIAA1454 ( 1265 res) fh15916 (1265) 163 29.0 1.3 KIAA0244 ( 2044 res) ha04644s1 (2044) 160 28.9 2.2 KIAA2012 ( 555 res) ah04096 ( 555) 147 27.0 2.3 KIAA0536 ( 1028 res) hg03863 (1028) 151 27.7 2.6 KIAA0799 ( 2111 res) fg01615y1 (2111) 155 28.5 3.2 KIAA1542 ( 1654 res) hh03408 (1654) 151 28.0 3.5 KIAA0741 ( 1222 res) hk04024 (1222) 147 27.4 3.8 KIAA0340 ( 1053 res) hg01396 (1053) 145 27.2 3.9 KIAA0577 ( 1043 res) hj00291 (1043) 142 26.9 4.8 FLJ00267 ( 1110 res) sj04085 (1110) 142 26.9 5 KIAA0783 ( 899 res) hk05408 ( 899) 140 26.6 5 KIAA0458 ( 1552 res) ef01252 (1552) 145 27.4 5 KIAA1408 ( 1298 res) fh04333(revised) (1298) 142 27.0 5.5 KIAA1826 ( 380 res) fj12317 ( 380) 129 25.1 6 KIAA1078 ( 1365 res) fg04938 (1365) 141 26.9 6.1 KIAA0551 ( 1385 res) hh00867s1 (1385) 141 26.9 6.1 FLJ00187 ( 563 res) sj02149 ( 563) 132 25.6 6.3 KIAA1853 ( 708 res) hj04155 ( 708) 134 25.9 6.4 KIAA1789 ( 477 res) fh23186 ( 477) 129 25.2 6.9 KIAA0155 ( 1195 res) ha02997 (1195) 135 26.3 8.3 KIAA0858 ( 1557 res) hh02535 (1557) 134 26.3 10 KIAA1116 ( 1330 res) hk02574(revised) (1330) 132 26.0 11 FLJ00034 ( 1343 res) as00034 (1343) 131 26.0 12 FLJ00386 ( 811 res) sj04204 ( 811) 126 25.2 12 KIAA1642 ( 1997 res) hh02864(revised) (1997) 134 26.5 12 KIAA1256 ( 1676 res) hh15293 (1676) 132 26.2 12 KIAA1102 ( 1101 res) bh00035 (1101) 128 25.6 13 KIAA0346 ( 1682 res) hg01508s1 (1682) 132 26.2 13 KIAA1864 ( 660 res) fj07836 ( 660) 123 24.8 13 KIAA0904 ( 1535 res) ha00554 (1535) 130 25.9 14 >>KIAA0853 ( 967 res) hk06136 (967 aa) initn: 574 init1: 243 opt: 321 Z-score: 186.9 bits: 43.9 E(): 3.3e-05 Smith-Waterman score: 359; 41.447% identity (73.026% similar) in 152 aa overlap (76-227:7-152) 50 60 70 80 90 100 FLJ004 DYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQR :::: :::: :.::.::.:::::.:.. .: KIAA08 KARRELERERARERE-REREKERDRERDRDRDH-DR 10 20 30 110 120 130 140 150 160 FLJ004 ERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPS ::::::::.:.:::.:..:: :::: .. :..:. :.:.::. ::..: . . :. . . KIAA08 ERERERERDREKEREREREERERERERERERERE-RERERERARERDKERERQRDWEDKD 40 50 60 70 80 90 170 180 190 200 210 220 FLJ004 RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS . .. ..: . . . .: :.::. .. : : :: .. .::. . ...: KIAA08 K-GRDDRREKREEIREDRNPRDGHDE-RKSKKRYRNEG-SPSPRQSPKRRREHSPDSDAY 100 110 120 130 140 150 FLJ004 NSSR :: KIAA08 NSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELK 160 170 180 190 200 210 >>KIAA0670 ( 1286 res) hk02359s1 (1286 aa) initn: 578 init1: 197 opt: 266 Z-score: 157.1 bits: 38.8 E(): 0.0015 Smith-Waterman score: 266; 40.659% identity (81.319% similar) in 91 aa overlap (70-159:1173-1263) 40 50 60 70 80 90 FLJ004 YADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRE : . . ..: :: .: .:::..:....: KIAA06 KKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEE 1150 1160 1170 1180 1190 1200 100 110 120 130 140 150 FLJ004 RERRQRERERERERERDKERQRRKEE-WERERAKRDEKDRQHRDRDREKEREKEKGKPKP .:...::.: ::::.:. ::..:.:. ::.: .. :..:.. ::::..::..:.:. . KIAA06 EEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERD 1210 1220 1230 1240 1250 1260 160 170 180 190 200 210 FLJ004 RSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTS : KIAA06 RRDTKRHSRSRSRSTPVRDRGGRR 1270 1280 >>KIAA0801 ( 1058 res) hg03949(revised) (1058 aa) initn: 278 init1: 157 opt: 228 Z-score: 138.5 bits: 35.1 E(): 0.016 Smith-Waterman score: 235; 31.618% identity (62.500% similar) in 136 aa overlap (75-199:69-203) 50 60 70 80 90 100 FLJ004 YDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQ :.:.:.::: .:.:...: : :::.: ::. KIAA08 ASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRER-SRSRDKRRSRSRDRKRLRRS 40 50 60 70 80 90 110 120 130 140 150 FLJ004 RERERERERERDKERQR-RKEEWERERAKRDE------KDRQHRDRDREKER----EKEK : :::.: ::: . :.: :.. : :..:.. :... ..:.: ::. :. : KIAA08 RSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSK 100 110 120 130 140 150 160 170 180 190 200 210 FLJ004 GKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARR : : .. . .. . . . .... : . ::. . : KIAA08 EKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEE 160 170 180 190 200 210 220 FLJ004 RRKTSASSASASNSSR KIAA08 MKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGG 220 230 240 250 260 270 >>KIAA0139 ( 1388 res) ha04032 (1388 aa) initn: 291 init1: 167 opt: 226 Z-score: 136.1 bits: 35.0 E(): 0.022 Smith-Waterman score: 240; 31.188% identity (56.931% similar) in 202 aa overlap (50-225:1161-1361) 20 30 40 50 60 70 FLJ004 TPVLLSDESSFSLALFRLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERER .:: : :. ..: ..::.:. KIAA01 DDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKP-GGWREKEK 1140 1150 1160 1170 1180 80 90 100 110 120 FLJ004 ERE------RENR---QRERERERERDRE---RERRQRERERERERERDKERQRR----K :: ::.: .:: .::.::::. ::. ... ::::.:::: .:. : . KIAA01 AREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPR 1190 1200 1210 1220 1230 1240 130 140 150 160 170 FLJ004 EE--WERERAK-----RDEKDRQHRDRD-REKEREKEKGKPKPRSPQPPSRQAEPPKKEA .: :.: :. :: . :. :::: :..::. .. . :. . . :: . KIAA01 DEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSE 1250 1260 1270 1280 1290 1300 180 190 200 210 220 FLJ004 ATTGPQVKRADEWKDPWRRSKSPKKKLGV-SVSPSRARRR-RKTSASSASASNSSR . .:::. :: . ..: ... ..: .: : : :. . . .:: KIAA01 REEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRE 1310 1320 1330 1340 1350 1360 KIAA01 SLRRTKNETDEDGWTTVRR 1370 1380 >>KIAA0138 ( 962 res) ha03743 (962 aa) initn: 770 init1: 177 opt: 213 Z-score: 131.2 bits: 33.6 E(): 0.041 Smith-Waterman score: 214; 35.878% identity (66.412% similar) in 131 aa overlap (54-174:603-731) 30 40 50 60 70 80 FLJ004 LSDESSFSLALFRLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERER :... .. . . : . .. . ...::: KIAA01 GSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRER 580 590 600 610 620 630 90 100 110 120 130 FLJ004 ENRQRERERE-RERDRERERRQRERER------ERERERDKERQRRKEEWERERAKRD-- : :::.:::: :: .:.:::.:::::. ::... .:.: . : .:.: .:. KIAA01 E-RQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERM 640 650 660 670 680 690 140 150 160 170 180 190 FLJ004 EKDRQHRDRDR-EKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWR :..: .:.: : :.::.::. . . : . :: : . : KIAA01 ERERLERERMRVERERRKEQERIH-REREELRRQQEQLRYEQERRPGRRPYDLDRRDDAY 700 710 720 730 740 750 200 210 220 FLJ004 RSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSR KIAA01 WPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYG 760 770 780 790 800 810 >>KIAA1019 ( 2309 res) fg00188s1 (2309 aa) initn: 231 init1: 119 opt: 218 Z-score: 129.5 bits: 34.6 E(): 0.052 Smith-Waterman score: 223; 29.518% identity (59.036% similar) in 166 aa overlap (72-229:1840-1999) 50 60 70 80 90 100 FLJ004 DPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERE :. :.: : . . :.: . . .:.. : KIAA10 KKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRS 1810 1820 1830 1840 1850 1860 110 120 130 140 150 FLJ004 RRQRERERERERERDKERQRRKEEWE-RERAKRDEKDRQHRDRDREKEREKEKG-KPKPR : . .:.:. : :.: : ::. : :.:. . .. ..: : : . :...: . . : KIAA10 RSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSR 1870 1880 1890 1900 1910 1920 160 170 180 190 200 210 FLJ004 SPQPPSRQAEPPKKEAA-TTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSR-----ARR .:. ::. : ... . ..: .: . .: :::..:... : .::: .:: KIAA10 TPSRRSRSHTPSRRRRSRSVG---RRRSFSISPSRRSRTPSRR---SRTPSRRSRTPSRR 1930 1940 1950 1960 1970 1980 220 FLJ004 RRKTSASSASASNSSR : : : . : :: KIAA10 SRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 1990 2000 2010 2020 2030 2040 >>KIAA0687 ( 1175 res) hk02992 (1175 aa) initn: 390 init1: 170 opt: 206 Z-score: 126.6 bits: 33.0 E(): 0.075 Smith-Waterman score: 223; 29.082% identity (61.224% similar) in 196 aa overlap (57-222:346-540) 30 40 50 60 70 80 FLJ004 ESSFSLALFRLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENR . :... : . . ...:..:. :.. KIAA06 RRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQ 320 330 340 350 360 370 90 100 110 120 130 FLJ004 QRERERERERDRERERRQRERERER-----ERERDKERQRRKEEWERERAKRDEK--DRQ :: :::: .:..:::.:.::.:..: ::.: .:..::. : :..:..:... :: KIAA06 QR-REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQ 380 390 400 410 420 430 140 150 160 170 180 FLJ004 HRDRDREKE-------REK-----EKGKPKPR-SPQPPSRQAEPPKKEAATTGPQVK--- ....:. : .:. .. .:.:. : ::: : : : . :... KIAA06 LEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEP 440 450 460 470 480 490 190 200 210 220 FLJ004 --RADEWKDPWRRSK--SPK---KKLGVSVSPSRARRRRKTSASSASASNSSR :: : .: .:... ::. :. : . : : .. : ... KIAA06 ADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQ 500 510 520 530 540 550 KIAA06 VPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSS 560 570 580 590 600 610 >>KIAA0182 ( 1157 res) ha02329s1 (1157 aa) initn: 324 init1: 184 opt: 204 Z-score: 125.6 bits: 32.8 E(): 0.084 Smith-Waterman score: 257; 44.531% identity (66.406% similar) in 128 aa overlap (62-181:270-389) 40 50 60 70 80 90 FLJ004 LALFRLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERE-NRQRER :.:. : . :::::::::: .:.::. KIAA01 HLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREK 240 250 260 270 280 290 100 110 120 130 140 FLJ004 ERERERDRERERRQRERERERERERDKERQRRKEEWERE--RAKRDEKD-----RQHRDR ::::::..:::. ..:::::.::::. ::::... :.: :: : . . : : KIAA01 EREREREKEREQ-EKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLR 300 310 320 330 340 350 150 160 170 180 190 200 FLJ004 DREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLG . : :.:::. . :.: :: :.:. .:. KIAA01 GHATE---ERGKPSEQ--LTPTR-AEK-LKDASLQAPKPVQHPLHPVPTPHHTVPSLISN 360 370 380 390 400 410 210 220 FLJ004 VSVSPSRARRRRKTSASSASASNSSR KIAA01 HGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGR 420 430 440 450 460 470 >>KIAA1172 ( 929 res) hj03919(revised) (929 aa) initn: 256 init1: 168 opt: 198 Z-score: 123.6 bits: 32.2 E(): 0.11 Smith-Waterman score: 198; 27.778% identity (63.333% similar) in 180 aa overlap (57-229:761-929) 30 40 50 60 70 80 FLJ004 ESSFSLALFRLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENR : ..:: . . . ... :..:: .: KIAA11 QQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRND--NRQQFNSGRDQERFGRRSFG 740 750 760 770 780 90 100 110 120 130 140 FLJ004 QR-ERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDR .: : .::: .:. .: . .:.:.. .:. .:.:... ::.: . ..::.. .::: KIAA11 NRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDR 790 800 810 820 830 840 150 160 170 180 190 FLJ004 EKEREKE--KGKPKPRSPQPP--SRQAEPPKKEAATTGPQVKRADEWKDPWRRSK--SPK :..:::: .:: ::. . .. .::: ..... : :.: . .. .:. KIAA11 ESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGN----VDTASELEKGVSEAAVLKPS 850 860 870 880 890 900 200 210 220 FLJ004 KKLGVSVSPSRARRRRKTSASSASASNSSR ..: :..: . .:.::... : KIAA11 EEL-----PAEATSSVEPEKDSGSAAEAPR 910 920 >>KIAA0332 ( 1028 res) hg00939 (1028 aa) initn: 243 init1: 117 opt: 187 Z-score: 117.4 bits: 31.2 E(): 0.24 Smith-Waterman score: 210; 24.378% identity (62.687% similar) in 201 aa overlap (40-229:816-1012) 10 20 30 40 50 60 FLJ004 SVPNVSCGLFTPVLLSDESSFSLALFRLEPYADPYYDYEIE-RFWRGGQY-ENFRVQYTE :..: . : .: . ... :. :.. : KIAA03 ESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLRE 790 800 810 820 830 840 70 80 90 100 110 120 FLJ004 TE----PYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRK : ... : .. .. ... ... :. ::. .: ..:.: ::::::::. ... KIAA03 IELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQR-EKEKELERERERDKKDKEKL 850 860 870 880 890 900 130 140 150 160 170 FLJ004 EEWERERAKRDE-----KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATT : ... ..:: :.:..: . .. .:. . .::.: :...: ..: . KIAA03 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGR-RVKSPSPKSERSE--RSERSHK 910 920 930 940 950 960 180 190 200 210 220 FLJ004 GPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSR . .:... .: ::. :.. . : .:.:.:: :. : .... .. :. KIAA03 ESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHK 970 980 990 1000 1010 1020 KIAA03 KSKKNKH 229 residues in 1 query sequences 2210765 residues in 2457 library sequences Tcomplib [34.26] (2 proc) start: Fri Feb 27 11:03:27 2009 done: Fri Feb 27 11:03:28 2009 Total Scan time: 0.390 Total Display time: 0.070 Function used was FASTA [version 34.26.5 April 26, 2007]