# 0 KIAA0949, 1559 aa # 1 KIAA1081 (1003 aa) # 2 KIAA1319 (1208 aa) # 3 KIAA1512 (2010 aa) # 4 KIAA2034 (1571 aa) # 5 KIAA0373 (1540 aa) // exp sw-scr id% from to 1 1.8e-06 437 23.4 166 971 2 1.2e-05 451 24.0 446 1176 3 8.4e-05 529 24.7 1009 1941 4 0.00011 484 22.7 522 1465 5 0.00022 416 23.8 200 1028 // 0 ( 1) LSLTKNCALLGEET----MMEQEMTRLHRRVSEVEAVLSQKE-------VELKASETQ-R 1 ( 166) .........................................Q-------TQLKEVLRE-N 2 ( 446) ...................LETQVMELQNKLKHVQGPEPAKE-------VLLKDLLET-R 3 ( 1009) .....NADLAARRR----KLEDECTELKKDIDDLELTLAKAE-------KEKQATENKVK 4 ( 522) .......ARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK-M 5 ( 200) LELEKNEMELKVEV----SKLREISDIARR--QVEILNAQQQ-------SRDKEVESL-R // 0 ( 49) SL------LEQDLATYITECSSLKRSLEQARMEVSQEDDK--AL--------Q--LLHDI 1 ( 177) DL------LRKDVE--VKE-SKLSSSMNSIKTFWSPELKK--ER--------A--LRKD- 2 ( 479) EL------LEEVLE-------GKQRVEEQLRLR--ERELT--AL--------KGALKEEV 3 ( 1053) NLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ--QVEDL 4 ( 574) KK------FEEDL--LLLEDQNSKLSKERKLLE-----DR--LA--------E--FSSQA 5 ( 246) MQ------LLDYQAQ--SDEKSLIAKLHQHNVSLQLSEAT--AL--------G--KLESI // 0 ( 91) R---EQSRKL--------QEIKEQ--E---YQAQVEEMRLMMN----------QLE---E 1 ( 215) -----EASKI--------TIWKEQ--Y---RVVQEENQHMQMT----------------- 2 ( 514) A---SRDQEV--------EHVRQQ------YQRDTEQLRRSMQ----------DAT---Q 3 ( 1111) ECSLEQEKKL--------RMDTER--A---KRKLEGDLKLTQESVADAAQDKQQLE---E 4 ( 609) A---EEEEKV--------KSLNKLRLK---YEATIADMEDRLR----------KEEKGRQ 5 ( 286) T---SKLQKMEAYNLRLEQKLDEK--EQALYYARLEG-RNRAK----------HLR---Q // 0 ( 122) DLVSARRRSDLYESELR--ESRLA----AEEFK----RKATECQHKLLKAKDQGKPEVGE 1 ( 240) --IQA------LQDELR--IQRDL----NQLFQ----QDSS---------SRTGEPCVAE 2 ( 544) DHAVLEAERQKMSALVR--GLQRE----LEETS----EETGHWQSMFQKNKEDLRATKQE 3 ( 1155) KL--KKKDSELSQLSLRVEDEQLL----GAQMQ----KKIKELQARAEELEEELEAERAA 4 ( 645) ELEKLKRRLDGESSELQ--EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG----GA 5 ( 327) TIQSLRRQ---FSGALP--LAQ------QEKFS----KTMIQLQNDKLKIMQEMKNSQQE // 0 ( 172) YAK--L--EKINAEQQL--KIQEL--QEKLE-------KAVKASTEATELLQNIR----- 1 ( 273) LTEENF--QRLHAEHER--QAKELFLLRKTL-------EEMELRIETQKQTLNAR----- 2 ( 594) LLQ--LRMEKEEMEEELGEKIEVL--QRELE-------QA-RASAGDTRQVEVLK----- 3 ( 1205) RAR--V--EKQRAEAAR--ELEEL--SERLE-------EAGGASAGQREGCRK-R----- 4 ( 699) RAQ--L--LKSLREAQA--ALAEA--QEDLESERVARTKAEKQRRDLGEELEALRGELED 5 ( 372) HRN--M--ENKTLEMEL--KLKGL--EE-LI-------STLKDTKGAQKVINWHM----- // 0 ( 212) -------QAKE-RAERELEKLQNREDSS-E--G------IRKKLVE-AEELEEKHR--EA 1 ( 317) -------D--E-SIKKLLEMLQ-----S-K--G------LSAKATE--EDHERTRRLAEA 2 ( 637) -------KELL-RTQEELKELQAERQSQ-EVAGRHRDRELEKQLAV-LRVEADRGR--EL 3 ( 1244) -------EAELGRLRRELEEAALRHEATVA--A------LRRKQAEGAAELGEQVD--SL 4 ( 751) TLDSTNAQQEL-RSKREQEVTELKKTLE-E--E------TRIHEAA-VQELRQRHG--QA 5 ( 411) -------KIEE-LRLQEL-KL-NRE--------------LVKDKEE-IKYLNNIIS--EY // 0 ( 252) QVS-AQHLEVHLKQKEQHYEE--KI-----KVLDNQIKKDLADKET-LE--NMMQRHEEE 1 ( 351) EMH-VHHLESLLEQKEK----------------ENSM----------LR--EEMHRRFEN 2 ( 685) EEQ-NLQLQKTLQQLRQDCEEASKA-----KMVAEAEATVLGQRRAAVE--TTLRETQEE 3 ( 1287) QRV-RQKLE---KEKSELRME---V-----DDLAANVETLTRAKAS-AE--KLCRTYEDQ 4 ( 798) LGELAEQLE-QARRGKGAWEK--TR-----LALEAEVSELRAELSS-LQ--TARQEGEQR 5 ( 444) ERT-ISSLEEEIVQQNKFHEE--RQMAWDQREVDLERQLDIFDRQQ-NEILNAAQKFEEA // 0 ( 301) AHE--------KGKILSEQKAMINAMDSKIRSLEQ--RIVELS-EAN------K-LAANS 1 ( 382) APD--------SAKTKALQ-TVIEMKDSKISSMER--GLRDLE-EEI------QMLKSNG 2 ( 737) NDEF-------RRRILGLEQQL-----KETRGL------VDGG-EAV------E-ARLRD 3 ( 1332) ---------------LSEAKI-------KVEELQR--QLADASTQRG------R-LQTES 4 ( 847) RRRLELQLQEVQGRAGDGERARAEAAE-KLQRAQA--ELENVS-GAL------N-EAESK 5 ( 500) T-----------GSIPDPSLPLPNQLEIALRKIKENIRIILET-RATCKSLEEK-LKEKE // 0 ( 343) SLF--TQRNMKAQE-------EMISELR------QQKFYLETQAGKLEAQ-NRK------ 1 ( 424) ALS--TEEREEEMK-------QM-EVYR------SHSKFMKNKIGQVKQELSRKDTELLA 2 ( 771) KL----QR-LEAEK-------QQLEEAL------NAS---QEEEGSLAAA-KRA------ 3 ( 1361) GEL--S-RLLEEKE-------CLISQLS------RGK---ALAAQSLEEL-RRQ------ 4 ( 896) TIR--LSKELSSTEAQLHDAQELLQEET------RAKLALGSRVRAMEAE-AAG------ 5 ( 547) SALRLAEQNILSRD-------KVINELRLRLPATAEREKLIAELGRKEME-PKS------ // 0 ( 381) LEEQLEKISH------QDHSD-KNRLLELETRLREV----S--LEH--EEQKLE-LKRQL 1 ( 468) LQTKLETLTN------Q-FSD-SKQHIEV---LKE-----S--LTA--KEQRAAILQTEV 2 ( 803) LEARLEEAQRGLARLGQEQQT-LNRALEEEGKQREVLRRGK--AEL--EEQKRL-LDRTV 3 ( 1395) LEEESKAKSA------LAHAV-QALRHDCDL-LREQ----H--EEE--AEAQAE-LQRLL 4 ( 941) LREQLEEEAA------ARERA-GRELQTAQAQLSEW----R--RRQ--EEEAGA-LEAGE 5 ( 593) --HHTLKIAH------QTIANMQARLNQKEEVLKKY----QRLLEKAREEQREI-VKKHE // 0 ( 425) TELQLSLQE-RESQL-TALQAARAA----LESQLRQAKTEL---EET-------TAEAEE 1 ( 508) DALRLRLEE-KETML-N--------------KKTKQIQDMA---EEK-------GTQAGE 2 ( 857) DRLNKELEKIGEDSK-QALQQLQAQ----LEDYKEKARREV---ADAQRQAKDWASEAEK 3 ( 1438) SKANAEVAQ-WRSKY-EADAIQRTE-------ELEEAKKKL---ALR-------LQEAEE 4 ( 985) EARRRAARE-AEA-L-TQRLAEKTETVDRLERGRRRLQQEL---DDA-------TMDLEQ 5 ( 640) EDLHILHHR-LELQADSSLNKFKQT----AWDLMKQSPTPVPTNKHF-------IRLAEM // 0 ( 469) EIQALTAHRDEIQRKFDAL--R----NSCTVITDLEEQLNQLTED----NAELNNQNFYL 1 ( 542) -IHDLKDMLDVKERKVNVL--QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTAL 2 ( 909) TSGGLSRLQDEIQRLRQAL------------------QASQAERD----TARLDKE--LL 3 ( 1479) GVEAANAKCSSLEKA--KL--R----LQ-TESEDVTLELERATSA----AAALDKKQRHL 4 ( 1032) QRQ-LVSTLEKKQRKFDQLLAE----EKAAVLRAVEER-ERAEAE----GREREARALSL 5 ( 688) E-QTVAEQDDSLSSLLVKL--K----K---VSQDLERQ-----RE----ITELKVKEFEN // 0 ( 519) SK-QLDEASGANDEIVQ-LRSEVDHLRREI----TEREMQLTSQK---QTMEALKTT--- 1 ( 599) TT--LEEALAEKERTIERLKEQRD---RDE----REKQEEIDNYK---KDLKDLKEK--- 2 ( 945) AQ-RLQ---GLEQEAEN-KKRSQDDRARQL----KGLEEKVSRLE---TELDEEKNT--- 3 ( 1526) ER-ALEERRRQEEE----MQRELEAAQRESRGLGTELFRLRHGHE---EALEALETLKRE 4 ( 1082) TR-ALEEEQEAREE----LERQNRALRAEL-------EALLSSKDDVGKSVHELERA--- 5 ( 729) IKLQLQE--NHEDEVKK-VKAEVEDLKYLL----DQSQKESQCLK---SELQAQKEA--- // 0 ( 567) CTML-------EEQVMD--LE----ALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQ 1 ( 644) VSLLQGDLSEKEASLLD--LKEHASSLASSGLKKDSRLKTLEIAL--EQKKEECLKMESQ 2 ( 990) VELL-------TDRVNR--GR----DQVDQLRTELMQERSARQDLECDKISLERQNKDLK 3 ( 1578) NKNL-------QEEISD--LT----DQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAE 4 ( 1127) CRVA-------EQAAND--LR----AQVTELEDELTAAE-------DAKLRLEVTVQALK 5 ( 776) NSRA-------PTTTMRNLVE----RLKSQLALKEKQQKALSRALLELRAEMTAAAEE-- // 0 ( 614) -RMLDTEK-----------QSRARA--DQRITESR-QVVELA--VK---EHKAEILA--- 1 ( 700) -LKKAHEA-----------ALEARA--SPEMSDRI-QHLERE--IT---RYKDESSK--- 2 ( 1037) TRLASSEG-----------FQKPSA--SLSQLESQNQLLQER--LQ---AEEREKTV--- 3 ( 1625) -GALELEETKTLRIQLELSQVKAEV--DRKLAEKD-EECANL--RR---NHQRAVES--- 4 ( 1167) -TQHERDL-----------QGRDEAGEERRRQLAK-QLRDAE--VERDEERKQRTLAVAA 5 ( 823) -RIISATS-----------QKEAHL--NVQQIVDR-HTRELKTQVE---DLNENLLK--- // 0 ( 651) ---LQQALK-EQKLKAESLSDK------LNDLEKK--HA-----M---LE-MNA--RSLQ 1 ( 737) ---AQAEVD-RLLEILKEVENE------KNDKDKK--IA-----E---LESLTS--RQVK 2 ( 1076) ---LQSTNR-KLERKVKELSIQ------IED-ERQ--HVNDQKDQ---LS-LRV--KALK 3 ( 1673) ---LQASLDAETRARNEALRLKKKMEGDLNDLELQLGHA-----TRQATE-AQAATRLMQ 4 ( 1212) RKKLEGELE-ELKAQMASAGQG------KEEAVKQ--LR-----K---MQ-AQM--KELW 5 ( 862) ---LKEALK-TSKNRENSLTDN------LNDLNNE-----------------------LQ // 0 ( 688) QKLETE---RELKQRL---LEEQAK-LQQQMDLQK---NHIFRLTQGLQ----------- 1 ( 775) DQNKKV---ANLKHKE---QVEKKK-SAQMLEEARRREDNLNDSSQQLQ----------- 2 ( 1117) RQVDEA---EEEIERL---DGLRKK-AQREVE-EQ---HEVNEQLQARI----------- 3 ( 1724) AQLKEEQAGRDEEQRLAAELHEQAQALERRASLLA---AELEELRAALE----------- 4 ( 1252) REVEET---RTSREEI---FSQNRE-SEKRLKGLE---AEVLRLQEELA----------- 5 ( 889) KK-------QKAYNKI---LREKEE-IDQENDELK---RQIKRLTSGLQGKPLTDNKQSL // 0 ( 727) -EA-----LDRAD-LLK-TERSDLEYQL-ENIQVLYS---HEK------VKMEGTISQQT 1 ( 817) -DS-----LRKKD-D-R-IE--ELEEALRESVQITAE---REM------V-----LAQEE 2 ( 1155) -KS-----LEKDS-WRK-ASRSAAESAL-KN............................. 3 ( 1770) -QGERSRRLAEQE-LLEATERLNLLHS--QNTGLL-----NQK------KKLEADLAQLS 4 ( 1291) --A-----SDRARRQAQ-QDRDEMADEV-ANGNLSKAAILEEK------RQLEGRLGQLE 5 ( 935) IEE-----LQRK---VK-KLENQLEGKV-EEVDLKPM---KEKNAKEELIRWEEGKKWQA // 0 ( 769) KLIDFL-QAKM-DQPAKK-KKVPLQYNELKLALEKEKARCAELE---EALQKTRIELRSA 1 ( 852) S-------ART-NAEKQV-EELLMAMEKVKQELESMKAKLSSTQ---QSLAEKETHLTNL 2 ( -) ............................................................ 3 ( 1815) GEVEEAAQERR-EAEEKA-KKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQAR 4 ( 1336) EELEEE-QSNS-ELLNDRYRKLLLQVESLTTELSAERSFSAKAE---SGRQQLERQIQEL 5 ( 982) K-IEGI-RNKLKEKEGEV-FTLTKQLNTLKDLFAKADKEKLTLQ---RKLKTT....... // 0 ( 823) R----EEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMS--LLAPPSSRRKES 1 ( 900) R----AE--RRK-----HLEEVLEMKQEALLAAI----SEKDANIA--LLELSSSKKK-- 2 ( -) ............................................................ 3 ( 1873) L----EEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALK--GVRKHERRVKEL 4 ( 1391) RGRLGEEDAGARAR---HKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEV 5 ( -) ............................................................ // 0 ( 877) STPEEFS--RRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHP 1 ( 941) -TQEEVAALKREKDRLVQQLKQQTQNRMKLMA............................ 2 ( -) ............................................................ 3 ( 1927) AYQAEED--RKNLARMQ........................................... 4 ( 1448) VLQVEEE--RRVADQLRDQL........................................ 5 ( -) ............................................................ // 0 ( 935) KCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQTKEPSSSLHLEGWMKVPRNNKRGQQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 995) GWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1055) PYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGN 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1115) SLLKLEGDDRLDMNCTLPFSDQVVLVGTEEGLYALNVLKNSLTHVPGIGAVFQIYIIKDL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1175) EKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDISPNIFEAVKGCHLFGAGKIENGLC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1235) ICAAMPSKVVILRYNENLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1295) EEFLDKNDHSLAPAVFAASSNSFPVSIVQVNSAGQREEYLLCFHEFGVFVDSYGRRSRTD 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1355) DLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSAGTPARAYLDIPNPRYLGPAISSG 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1415) AIYLASSYQDKLRVICCKGNLVKESGTEHHRGPSTSRSPNKRGPPTYNEHITKRVASSPA 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1475) PPEGPSHPREPSTPHRYREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1535) RGRLPAGAVRTPLSQVNKVWDQSSV 1 ( -) ......................... 2 ( -) ......................... 3 ( -) ......................... 4 ( -) ......................... 5 ( -) ......................... //