# 0 KIAA0381, 1114 aa # 1 KIAA0666 (1085 aa) # 2 KIAA1902 (1112 aa) # 3 KIAA2014 (1032 aa) # 4 KIAA1695 (1199 aa) // exp sw-scr id% from to 1 1.3e-71 4857 67.7 8 1085 2 2.2e-16 1241 26.7 11 1102 3 4.7e-16 1150 26.8 23 1005 4 1.1e-07 506 26.1 606 1120 // 0 ( 1) GARSSERSAGGGAVPRAAGARAPWGPRNHNEDLGHLSADAPWPAVTMAPRKRSHHGLGFL 1 ( 8) ..............................................MAPRKRGGRGISFI 2 ( 11) ...............................................SPRPRRAADMG-- 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 61) -CCFGGSDIPEINLR----DNHPLQFMEFSSPIPNAEELNIRFAELVDELDLT-DKNREA 1 ( 22) FCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEELDVMFSELVDELDLT-DKHREA 2 ( 22) --NAGSMDSQQTDFRA---HNVPLKL-----PMPEPGELEERFAIVLNAMNLPPDKAR-L 3 ( 23) ......................PLLLPPGKMPMPEPCELEERFALVLSSMNLP-PDKARL 4 ( -) ............................................................ // 0 ( 115) MFALPPEKKWQIYCSKKKEQ-EDPNKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRN 1 ( 81) MFALPAEKKWQIYCSKKKDQ-EE-NKGATSWPEFYIDQLNSMAARKSLLALEKEEEEERS 2 ( 71) LRQYDNEKKWELICDQERFQVKNP-------PHTYIQKLKGYLDPAVTRKKFRRRVQEST 3 ( 60) LRQYDNEKKWDLICDQERFQVKNP-------PHTYIQKLQSFLDPSVTRKKFRRRVQEST 4 ( -) ............................................................ // 0 ( 174) QVVEDLKTALRTQPMRFVTRFI--ELE--GLTCLLNFL---------------------- 1 ( 139) KTIESLKTALRTKPMRFVTRFI--DLD--GLSCILNFL---------------------- 2 ( 124) QVLRELEISLRTNHIGWVREFL--NEENKGLDVLVEYL---------------------- 3 ( 113) KVLRELEISLRTNHIGWVREFLNDENK--GLDVLVDYLSFAQCSVMFDFEGLESGDDGAF 4 ( -) ............................................................ // 0 ( 208) -------R------SMD---------------------------------HATCESR--- 1 ( 173) -------K------TMD---------------------------------YETSESR--- 2 ( 160) -------SFAQYAVTFD---------------------------------FESVEST--- 3 ( 171) DKLRSWSR------SIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVS 4 ( -) ............................................................ // 0 ( 219) ----IHTSL----------------------IG--------------------------- 1 ( 184) ----IHTSL----------------------IG--------------------------- 2 ( 177) ----VESSVDKSKPWSRSIEDLHRGSNLPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSR 3 ( 225) QKDDVHVCI----------------------L---------------------------- 4 ( -) ............................................................ // 0 ( 226) -------------CIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAV 1 ( 191) -------------CIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAV 2 ( 233) LVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAV 3 ( 235) -------------CLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAV 4 ( -) ............................................................ // 0 ( 273) CLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRD-E-VNLKTAIMSFINAV 1 ( 238) CLVPGGHKKVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRD-E-VSLKTAIMSFINAV 2 ( 293) CLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHF-----RNED-NNIDFMVASMQFINIV 3 ( 282) CLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYF-----RNEDSN-IDFMVACMQFINIV 4 ( -) ............................................................ // 0 ( 331) LNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLD-FFEMVRNEDDLELA 1 ( 296) LSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLD-FFEMLRNEDELEFA 2 ( 347) VHS---VEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGAL--- 3 ( 336) VHS---VEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ-AY----------LD 4 ( -) ............................................................ // 0 ( 390) RRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDR 1 ( 355) KRFELVHIDTKSATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDR 2 ( 401) ----LEDAETKNAA---------LERVEELEENISHLSEKLQ--DTENEAMSKIVELEKQ 3 ( 382) NVFDVGGLLEDAETKNVAL--EKVEELE---------EHVSHLTEK----------LLD- 4 ( -) ............................................................ // 0 ( 450) ILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLE 1 ( 415) IIQQIVIQNDKGQDPDSTPLENFNIKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLE 2 ( 446) LMQR---NKELDVVREIYKDANTQVHTLRKMV--------------KEKEEAIQRQSTLE 3 ( 420) -------------------LENENMMRVA------------------------ELEKQLL 4 ( -) ............................................................ // 0 ( 510) RKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVA------QLSELSTG 1 ( 475) KKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTA------QLHELSRR 2 ( 489) KKIHE-----LEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSG 3 ( 437) QREKELESIKETYENTSHQVHTLR-RLIKEKEEAFQRRCHLEPNVR------GLESVDSE 4 ( -) ............................................................ // 0 ( 564) PVS-------SPPPP-----GGPLTLSSSMTTNDLP---PPPPP-LPFACCPPPPPPPLP 1 ( 529) AVCASIPGGPSPGAP-----GGPF--PSSVPGSLLP---PPPPPPLPGGMLPPPPPP-LP 2 ( 544) PLP-------PPPPPLPPSSDTPETVQNGPVTPPMP---PPPPP-PPPPPPPPPPPPPPP 3 ( 490) ALA-------RV---------GPAELSEGMPPSDLDLLAPAPPP-EEVLPLPPPPAPPLP 4 ( 606) ...................................P---PPPPP-PTFLGLPPPPPPPLL // 0 ( 608) P-GGP-----PTP-PGA-----PPCLG--MGLPLP-QDPYPSS--DVPLRKKRVPQPSHP 1 ( 578) P-GGP-----PPP-PGP-----PP-LG--AIMPPP-GAPM-----GLALKKKSIPQPTNA 2 ( 593) PLPGPASETVPAP-PLA-----PP-LP--SAPPLP-GTSSPTVVFNSGLAAVKIKKPIKT 3 ( 533) P-PPP-----PLP-DKC-----PP------APPLPGAAPSVVL--TVGLSAIRIKKPIKT 4 ( 627) D-SIP-----PPPVPGNLLVPPPPVFNAPQGLGWS-QVPRGQP--TFTKKKKTIRLFWNE // 0 ( 651) ---LKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMF-SAYQRHQ--------- 1 ( 617) ---LKSFNWSKLPENKLEGTVWTEIDDTKVFKILDLEDLERTF-SAYQRQQDFFVNSNSK 2 ( 643) KFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPA--------- 3 ( 573) KFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKTKAQGPA--------- 4 ( 678) ---VRPFDWPCKNNRRCREFLWSKLEPIKV----DTSRLEHLF----ESKS--------- // 0 ( 698) -KELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAK 1 ( 673) QKEADAIDDTLSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPK 2 ( 694) -IDLSSSKQ-KIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFD-LKTLPV 3 ( 624) -LDLICSKN-KTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT-LPV 4 ( 718) -KELSVSKKTA-ADGKRQEIIVLDSKRSNAINIGLTVLP-PPRTIKIAILNFDEYA-LNK // 0 ( 757) DMLEQLLKFIP---EKSDIDLL---EEHKHE---IERMARADRFLYEMSRIDHYQQRLQA 1 ( 733) DMLEQLLKFVP---EKSDIDLL---EEHKHE---LDRMAKADRFLFEMSRINHYQQRLQS 2 ( 751) DFVECLMRFLP---TENEVKVLRLYERERKP---LENLSDEDRFMMQFSKIERLMQKMTI 3 ( 681) DFVECLMRFLP---TEAEVKLL---RQYERERQPLEELAAEDRFMLLFSKVERLTQRMAG 4 ( 774) EGIEKILTMIPTDEEKQKIQEA---QLANPE---IP-LGSAEQFLLTLSSISELSARLHL // 0 ( 808) LFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFR 1 ( 784) LYFKKKFAERVAEVKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQRGNAYGFK 2 ( 805) MAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFK 3 ( 735) MAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFK 4 ( 827) WAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLN-GT--NAKAFE // 0 ( 868) VASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEV 1 ( 844) ISSLNKIADTKSSIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEI 2 ( 865) LQSLDLLLDTKST-DRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDV 3 ( 795) LQSLDLLLDTKST-DRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDV 4 ( 884) LSYLEKVPEVKDTVHKQ-SLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNL // 0 ( 928) GNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKA 1 ( 904) STLRSGLKAVETELEYQKSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKA 2 ( 924) KELQRGMDLTKREYTMHDHNT---------LLKEFILNNEGKLKKLQDDAKIAQDAFDDV 3 ( 854) KELGRGMELIR----------RECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAV 4 ( 943) CQMERRCKASWDHLKAIAKHEMKPVLK--QRMSEFLKDCAERIIILKIVHRRIINRFHSF // 0 ( 988) LMHFGEHDSKMQP---DEFFGIFDTFLQAFSEARQD-LEAMRRRKEEE--ERRARMEAM- 1 ( 964) VKHFGEEAGKIQP---DEFFGIFDQFLQAVSEAKQE-NENMRKKKEEE--ERRARMEAQ- 2 ( 975) VKYFGENPKTTPP---SVFFPVFVRFVKAYKQAEEE-NE-LRKKQEQALMEKLLEQEAL- 3 ( 904) VRYFGESPKTTPP---SVFFPVFVRFIRSYKEAEQE-NEA--RKKQEE--VMREKQLAQE 4 ( 1001) LLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHR--ERNKTRGKM- // 0 ( 1041) -----LKEQRER---ERWQRQ-------RKVLAA---------GSSL-EEG--GEFDDLV 1 ( 1017) -----LKEQRER---ERKMRK-------AK--------------ENS-EES--GEFDDLV 2 ( 1029) -----MEQQDPKSPSHKSKRQ-------QQELIAELRRRQVKDNRHV-YEGKDGAIEDII 3 ( 956) AKKLDAKTPSQR---NKWQQQELIAELRRRQAKE---------HRPV-YEGKDGTIEDII 4 ( 1058) -----ITDSGKF---SGSSPA-------PPSQPQ---------GLSYAEDA--AEHENMK // 0 ( 1074) SALRSGEVFDKD----LCKLKRS-RKRSGSQALEVTRERAINRLNY 1 ( 1045) SALRSGEVFDKD----LSKLKRN-RKRITNQMTDSSRERPITKLNF 2 ( 1076) TDLRNQPYRRAD------AVRRSVRRRFDDQNL............. 3 ( 1003) TGL-----...................................... 4 ( 1092) AVLKTSSPSVEDATPALGVRTRS-RASRGS................ //