# 0 KIAA1335, 2041 aa # 1 KIAA1564 (2432 aa) # 2 KIAA1416 (1966 aa) # 3 KIAA0308 (2759 aa) # 4 KIAA0444 (978 aa) # 5 KIAA1259 (1561 aa) // exp sw-scr id% from to 1 8.8e-164 4324 65.4 876 1861 2 1.2e-139 4855 47.8 420 1966 3 7.5e-129 4832 43.7 951 2739 4 1.2e-22 720 30.4 2 604 5 4.2e-15 510 36.9 1099 1351 // 0 ( 1) LKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNL 1 ( 876) LKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGAGHTNMPNL 2 ( 420) LKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANVPNL 3 ( 951) LKPMMLRRLKEDVEKKLAPKEETIIEVELTNIQKKYYRAILEKNFSFLSKGAGQTNVPNL 4 ( 2) .......................................................NQVSL 5 ( -) ............................................................ // 0 ( 61) INTMMELRKCCNHPYL--INGAEEKILEDFRKTHSPDAPDFQLQAMIQAAGKLVLIDKLL 1 ( 936) LNTMMELRKCCNHPYL--INGAEEKILTEFREACHIIPHDFHLQAMVRSAGKLVLIDKLL 2 ( 480) LNTMMELRKCCNHPYL--INGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKLL 3 ( 1011) VNTMMELRKCCNHPYL--IKGAEEKILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLL 4 ( 7) LNIMMDLKKCCNHPYLFPVAAVEAPVL--------PNG-SYDGSSLVKSSGKLMLLQKML 5 ( 1099) ...........................................ESLITDSGKLYALDVLL // 0 ( 119) PKLIAGGHKVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDR 1 ( 994) PKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDR 2 ( 538) PKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDR 3 ( 1069) PKMKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDR 4 ( 58) KKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQ 5 ( 1116) TRLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADF-QNRNDI // 0 ( 179) FVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNS 1 ( 1054) FVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNS 2 ( 598) FVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNS 3 ( 1129) FVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNS 4 ( 118) FCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRAS 5 ( 1175) FVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGT // 0 ( 239) YEREMFDKASLKLGLDKAVLQD-IN-RKGGTN-----------GVQQLSKM-----EVED 1 ( 1114) YEREMFDKASLKLGLDKAVLQS-MSGRDGNIT-----------GIQQFSKK-----EIED 2 ( 658) YEREMFDKASLKLGLDKAVLQS-MSGRENATN-----------GVQQLSKK-----EIED 3 ( 1189) YEREMFDRASLKLGLDKAVLQS-MSGRESNVG-----------GIQQLSKK-----EIED 4 ( 178) VEERITQVAKRKMMLTHLVVRPGLG-SKSGSMTKQELDDILKFGTEELFKD-----DVEG 5 ( 1235) IEERILQRAKEKSEIQRMVISG-GN-FKPDTL-----------KPKEVVSLLLDDEELEK // 0 ( 281) LLRKGAY-------------GALM-------------DEED-EGSKFCEED---IDQILQ 1 ( 1157) LLRKGAY-------------AAIM-------------EEDD-EGSKFCEED---IDQILL 2 ( 701) LLRKGAY-------------GALM-------------DEED-EGSKFCEED---IDQILL 3 ( 1232) LLRRGAY-------------GAIM-------------EEED-EGSKFCEED---IDQILL 4 ( 232) MMSQGQRPVTPIPDVQSSKGGNLAASAKKKHGSTPPGDNKDVEDSSVIHYDDAAISKLLD 5 ( 1282) KLRLRQE-------------EKRQ-------------QEET-NRVKERKRK---REKYAE // 0 ( 311) RR---THTITIQSEGK--G-STFAKASFVA---SG----NRTDISLD---DPNFWQKWAK 1 ( 1187) RR---TTTITIESEGK--G-STFAKASFVA---SE----NRTDISLD---DPNFWQKWAK 2 ( 731) RR---THTITIESEGK--G-STFAKASFVA---SG----NRTDISLD---DPNFWQKWAK 3 ( 1262) RR---TKTITIESEGR--G-STFAKASFVA---SG----NRTDISLD---DPNFWQKWAK 4 ( 292) RNQDATDDTELQNMNE--YLSSFKVAQYVVREEDGVEEVEREIIKQEENVDPDYWEKLLR 5 ( 1312) KK---KKEDELDGKRRKEG-VNLV-IPFVP---SA----DNSNLSADG--DDSF...... // 0 ( 355) IAELDTEAKNEKESLVIDRPRVRKQTKHYNSFEED-----ELM----EFS----ELDSDS 1 ( 1231) KADLDMDLLNSKNNLVIDTPRVRKQTRHFSTLKDD-----DLV----EFS----DLESED 2 ( 775) KAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKED-----ELM----EFS----DLESDS 3 ( 1306) KAEIDIEAISGRNSLVIDTPRIRKQTRPF-SATKD-----ELA----ELS----EAESEG 4 ( 350) -HHYEQQQEDLARNLGKGK-RIRKQVNYNDASQEDQEWQDELSDNQSEYSIGSEDEDEDF 5 ( -) ............................................................ // 0 ( 402) DERP-T--RSRRLNDKARRYLRAE--------CFRVEKNLLIFGWG-RWKDILTHGRFKW 1 ( 1278) DERP----RSRR-HDRHHAYGRTD--------CFRVEKHLLVYGWG-RWRDILSHGRFKR 2 ( 822) EEKPCA--KPRRPQDKSQGYARSE--------CFRVEKNLLVYGWG-RWTDILSHGRYKR 3 ( 1352) DEKP----KLRRPCDRSNGYGRTE--------CFRVEKNLLVYGWG-RWREILSHGRFKR 4 ( 408) EERP-EGQSGRR---QSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRW 5 ( -) ............................................................ // 0 ( 450) HLNEKDM---EMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQN---HSGLS 1 ( 1324) RMTERDV---ETICRAILVYCLLHYRGDENIKGFIWDLISPAENGKTKELQN---HSGLS 2 ( 871) QLTEQDV---ETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVN---HSGLS 3 ( 1399) QLNEHDV---EIICRALLAYCLVHYRGDEKIKGFIWDLITPTEDGQTRELQN---HLGLS 4 ( 464) GMPPQDAFNSHWLVRDLRGKSEKEFRA--YVSLFMRHLCEPGADG-AETFADGVPREGLS 5 ( -) ............................................................ // 0 ( 504) APVPRGRKGKKTKNQLLIPELKDADWLATCNPEVVLHDDGYKKHLKQHCNKVLLRVRMLY 1 ( 1378) IPVPRGRKGKKVKSQSTF-DIHKADWIRKYNPDTLFQDESYKKHLKHQCNKVLLRVRMLY 2 ( 925) APVPRGRKGKKVKAQSTQPVVQDADWLASCNPDALFQEDSYKKHLKHHCNKVLLRVRMLY 3 ( 1453) APVPRGRKGKKVKTQTSSFDIQKAEWLRKYNPEQLLQDEGYKKHIKHHCNKVLLRVRMLY 4 ( 521) RQHVLTRIGVMSLVRKKVQEFEHVNGKYS-TPDLIPEGPEGKK----------------- 5 ( -) ............................................................ // 0 ( 564) YLKAEILGEAAEKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERY 1 ( 1437) YLRQEVIGDQAEKVLGGAIASEIDIWFPVVDQLEVPTTWWDSEADKSLLIGVFKHGYEKY 2 ( 985) YLRQEVIGDQADKILEGADSSEADVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKY 3 ( 1513) YLKQEVIGNECQKVFDGVDASDIDVWVPEPDHSEVPAEWWDFDADKSLLIGVFKHGYEKY 4 ( 563) --PGEVISSDPNTPVPASPAHLLPAPLGLPDKMEAQLGYMD-EKD............... 5 ( -) ............................................................ // 0 ( 624) NAMRADPALCFLEKVGMPDEKSLSAEQGVTD---GTSDIPERGNTDK--EDNAEDKVDGL 1 ( 1497) NTMRADPALCFLEKAGRPDDKAIAAEHRVLD---NFSDIVEGVDFDK---DCEDPEYKPL 2 ( 1045) NSMRADPALCFLERVGMPDAKAIAAEQRGTD---MLADGGDGGEFDR--EDE-DPEYKPT 3 ( 1573) NTIRADPALCFLERVGKPDEKAVAAEQRANDYMDGDVEDPEYKPAPAIFKDDIEDDV--- 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 679) QKQTESSSDGGDGVFSEKKD----DS-------RAAQDGSDPDKSPWPVSSALTARLRRL 1 ( 1551) QGPPKDQDDEGDPLMMMDEEISVIDG-------DEAQVTQQPGHLFWPPGSALTARLRRL 2 ( 1099) RTPFKDEIDEFANSPSEDKE----ESMEIHATGKHSESNAELGQLYWPNTSTLTTRLRRL 3 ( 1630) -------SSPGDLVIA---D----GD-------GQLMEG---DKVYWPTQSALTTRLRRL 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 728) VTVYQRCNRK---ELCRPEILGPGNQGYWVQEEMFRRT-SEMDLINK-EAQKRWTRREQA 1 ( 1604) VTAYQRSYKR---EQMKIEAAERGDRRRRRCEAAFKLK----EIARR-EKQQRWTRREQT 2 ( 1155) ITAYQRSYKR---QQMRQEALMKTDRRRRRPREEVRALEAEREAIIS-EKRQKWTRREEA 3 ( 1666) ITAYQRTNKNRQIQQIQPTFSVPTSVMQPIYEEA---T-LNPKMAAKIERQQRWTRREEA 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 783) DFYRTVSSFGVVYDQEKKTFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWK 1 ( 1656) DFYRVVSTFGVEYDPDTMQFHWDRFRTFARLDKKTDESLTKYFHGFVAMCRQVCRLPPAA 2 ( 1211) DFYRVVSTFGVIFDPVKQQFDWNQFRAFARLDKKSDESLEKYFSCFVAMCRRVCRMPVKP 3 ( 1722) DFYRVVSTFGVVFDPDRGQFDWTKFRAMARLHKKTDDSLEKYLYAFMSMCRRVCRLPSKE 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 843) DGGPPDTTIYVEPITEERAARTLYRIELLRKVREQVLKCPQLHERLQLCRP-SLYLPVWW 1 ( 1716) GDEPPDPNLFIEPITEERASRTLYRIELLRRLREQVLCHPLLEDRLALCQPPGPELPKWW 2 ( 1271) DDEPPDLSSIIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQP-SLDLPEWW 3 ( 1782) ELVDPN--IFIQPITEERASRTLYRIELLRKVREQALRHPQLFERLKLCHP-NPDLPVWW 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 902) ECGKHDRDLLIGTAKHGLNRTDCYIMNDPQLSFLDAYRNYAQHKRSGTQAPGNLCCLYQT 1 ( 1776) EPVRHDGELLRGAARHGVSQTDCNIMQDPDFSFLAARMNYMQNHQAGAPAPSLSRCSTPL 2 ( 1330) ECGRHDRDLLVGAAKHGVSRTDYHILNDPELSFLDAHKNFAQNRGAGNTSSLN------- 3 ( 1839) ECGPHDRDLLIGAAKHGVSRTDYHILRDPELSFMAAQRNYSQSKMAHSRTSTPLLQQYQV 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 962) NSKLYESLTYSQMS-RTSESLENEPENLVRVESRDDHLSLPDVTCENFISKVQDVISINH 1 ( 1836) LHQQYTSRTASPLPLRPDAPVEKSPE.................................. 2 ( 1383) ------------------------PLAVGFVQT-------PPVISSAHI----------Q 3 ( 1899) ------ALSASPLT------------------------SLP---------RLLDAKGII- 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1021) DESLLPESLESMMYGKKVLSQEPSSFQESPSTNTESRKDVITISISKDGNCQSGGPEAEI 1 ( -) ............................................................ 2 ( 1402) DERVL-EQAE----GK---VEEP----ENPAAKEK---------------CE-GKEEEEE 3 ( 1919) --------LEEMKVKSENLKEEPQSSEEESMSSVETRTLIKSEPVS---------PKNGV 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1081) ASGPTFMGSLEAGGVAQANIKNGKHLLMSISKEGELCCSEAGQRPENIGQLEAKCLASPS 1 ( -) ............................................................ 2 ( 1434) TDG------------------SGKE-----SKQE--CEAEASSVKNELKGVEV------- 3 ( 1962) L--PQATGDQKSGGKCETDRR------MVAARTEPLTPNPASKKP----RVHKR------ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1141) LNPGNESGFVDMCSLSVCDSKRNLSSDQQLIDLLENKSLESKLILSQNHSDEEEEEEENE 1 ( -) ............................................................ 2 ( 1462) ---GADTG---------------------------SKSISEK-------GSEEDEEEKLE 3 ( 2004) ---GSESS-----SDSDSDSERSSCS---------SRSSSSSSSSSCSHS---------- 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1201) EENLAMAVGMGERPEVLHLTEPTTNISREKNQGFQDETKKGSLEVANQTPGLQRAFPAPA 1 ( -) ............................................................ 2 ( 1485) DDDKSEE---SSQPE-------AGAVSRGKN--F-DEESNASMSTAR------------- 3 ( 2037) --------------------------------------RSGS--------------SSSS 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1261) ACQCHCKHMERWMHGLENDEFEIEKPKAYIPDLFKSKTNTIAMEGEPTAIPSQPFKVKHE 1 ( -) ............................................................ 2 ( -) ------------------------------------------------------------ 3 ( 2045) SSSC-------------------------------SSASSSSSSSTSSSSSS-------- 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1321) LLKEPWKESAEGQNVFPTYPLEGSELKSEDMDFENKDDYDR-DGNCHSQDYPGKYSEEES 1 ( -) ............................................................ 2 ( 1519) -------------------------------------DETR-DGF---------YMED-- 3 ( 2066) -----------------------SSSSSEESDSDEEEAQKRAESTTHMKAY-----DEES 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1380) KSSTSGITGDIGDELQEARA-PTIAQLLQEKTLYSFSEWPKDRVIINRLDNICHVVLKGK 1 ( -) ............................................................ 2 ( 1530) -----------GD--------PSVAQLLHERT-FAFSFWPKDRVMINRLDNICEAVLKGK 3 ( 2098) VASLSTTQDETQDSFQMNNGTPESAYILQGGYMLAASYWPKDRVMINRLDSICQTVLKGK 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1439) WPSS--QQYEPSGTLP---TPVLTSSAGSRTSLSEPEA---AEHSFSNGAAL------AA 1 ( -) ............................................................ 2 ( 1570) WPVNRRQMFDFQGLIPGY-TPTTVDSPLQKRSFAELSMVGQASISGSEDITT------SP 3 ( 2158) WPSA--RRSYDANTVASFYTTKLLDSPGAATEYSEPSV---PTPP---GAGVKEEHDQST 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1485) QIHKESFLAPVFTKDEQKHRRPYEFEVERDAKARGLEQFSATHGHTPIIL-NGWHGESAM 1 ( -) ............................................................ 2 ( 1623) QLSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQ--EKVV 3 ( 2210) QMSKEGGLKLTFQKQGLAQKRPFDGE---DG-ALGQQQYLTR----------------LR 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1544) DLSCSSEGSPGATSPFPVSASTPKIGAISS-LQGALGMDLSGILQAGLIHPVTGQIVNGS 1 ( -) ............................................................ 2 ( 1681) DLSKASREATSSTSNFSSLSSKFILPNVSTPVSDAFKTQME-LLQAGLSRTPTRHLLNGS 3 ( 2250) ELQSASETS---LVNFP--KSIPVSG--TS-IQPTLG-------------------ANGV 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1603) LRRDDAATRRRRGRRKHVEGGMDLIFL--KEQT----LQAGILEVHE--DPG-QATLSTT 1 ( -) ............................................................ 2 ( 1740) LVDGEPPMKRRRGRRKNVEG-LDLLFMSHKRTS----LSAEDAEVTKAFEED-IETPPTR 3 ( 2283) ILDNQPIVKKRRGRRKNVEG-VDIFFF--NRNKPPNHVSLGLTSSQI--STGINPALSYT 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1654) HPEGPG---PATSAPEPATA---ASSQ--AEKSIPS-KSLLDWLRQQADYSLEVPGFGAN 1 ( -) ............................................................ 2 ( 1794) NIPSPGQLDPDTRIPVINLE---DGTRLVGEDAPKN-KDLVEWLKLHPTYTVDMPSYVPK 3 ( 2338) QPQGI----PDTESPVPVINLKDGTRL--AGDDAPKRKDLEKWLKEHPGYVEDLGAFIPR 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1705) FS---D-------KPKQRRPRCKEPGKLDVSSLSGEERVPAIPKE----------PGLR- 1 ( -) ............................................................ 2 ( 1850) NA---DVLFSSFQKPKQKRHRCRNPNKLDINTLTGEERVPVVNKR----------NGKKM 3 ( 2392) MQLHEG-------RPKQKRHRCRNPNKLDVNSLTGEERVQLINRRNARKVGGAFAPPLKD 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1744) ----------------------------------GFLPENKFNHTLAEPILRDTGPRRRG 1 ( -) ............................................................ 2 ( 1897) GGAMAPPMKDLPRWLEENPEFAVAPDWTDIVKQSGFVPESMFDRLLTGPVVRGEGASRRG 3 ( 2445) LCRFLKENSEYGVAPEWGDVVKQS----------GFLPESMYERILTGPVVREE-VSRRG 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1770) RRPRSELLKAPSIVA----DSPSGMGPLFMNGLIAGMDLVGLQ----NMRNMPGIPLT-G 1 ( -) ............................................................ 2 ( 1957) RRPKSEIARA.................................................. 3 ( 2494) RRPKSGIAKATAAAAAASATSVSG-NPLLANGLLPGVDLTTLQALQQNLQNLQSLQVTAG 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1821) LVGFPAGFATMPTGEEVKSTLSMLPMMLPGMAAVPQMFGVGGLLSPPMATTCTSTAPASL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2553) LMGMPTG---LPSGGEAKNMAAMFPMLLSGMAGLPNLLGMGGLLTKP---TESGTEDKK- 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1881) SSTTKSGTAVTEKTAEDKPSSHDVKTDTLAEDKPGPGPFSDQSEPAITTSSPVAFNPFLI 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2606) GSDSKESEGKTERT--ESQSSENGGENSVS---SSPSASSTAALNTAAAANPLALNPLLL 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1941) PGVSPGLIYPSMFLSPGMGMALPAMQQA-------RHSEIVGLESQKRKKKKTKGDNPNS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2661) SNI----LYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLGSSKSVEVKEEDSRIKDQED 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1994) HPEPAPSCEREPSGDENCAEPSAPLPAEREHGAQAGEGALKDSNNDTN 1 ( -) ................................................ 2 ( -) ................................................ 3 ( 2717) KGGTEPSPLNENSTDEGSEKADA......................... 4 ( -) ................................................ 5 ( -) ................................................ //