# 0 KIAA1124, 1760 aa # 1 KIAA0451 (983 aa) # 2 KIAA0619 (1428 aa) # 3 KIAA0561 (1308 aa) # 4 KIAA0303 (2137 aa) # 5 KIAA0807 (1329 aa) // exp sw-scr id% from to 1 2.4e-58 3271 52.1 1 982 2 6e-32 1699 29.8 12 1296 3 5.3e-11 679 31.2 365 779 4 7e-11 682 30.3 53 484 5 7.4e-11 674 35.8 41 345 // 0 ( 1) AGARRRGRGGEEAPLLPGLAAAEPPRARPD------GLAEPAVRGRRVG---SGPRGTMS 1 ( -) ............................................................ 2 ( 12) ......GAGGSGAVLGP--EAAGPEREEPECGSSGGGMSRPPPTGKMPGAPETAP-GDGA 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 52) AKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPF 1 ( -) ............................................................ 2 ( 63) GASRQRKLEALIRD-P---RSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKI 3 ( -) ............................................................ 4 ( 53) ..............................................DSGTAETPETDESV 5 ( -) ............................................................ // 0 ( 112) TQLVKEMQLHRE----DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAET 1 ( -) ............................................................ 2 ( 119) VKKIRGLQMKAE----DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDS 3 ( 365) ................DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQI 4 ( 67) SSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQI 5 ( 41) ...........E----DFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQI // 0 ( 168) ACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMAR 1 ( -) ............................................................ 2 ( 175) AFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYD--VPEKWAK 3 ( 409) QQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNM-GPLPVDMAR 4 ( 127) QQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLM-KNMGPLPVDMAR 5 ( 86) QQAFVERDILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNI-GALPVDMVR // 0 ( 228) FYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFG----SCLKMND------D 1 ( -) ............................................................ 2 ( 233) FYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFG----TCMKMDE------T 3 ( 468) LYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMAT------N 4 ( 186) MYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTT------N 5 ( 145) LYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGL---SKMGLMSLTTNLYE // 0 ( 278) ---GTVQSSV-------AVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGE 1 ( -) ............................................................ 2 ( 283) ---GMVHCDT-------AVGTPDYISPEVLKS-QGGDGFYGRECDWWSVGVFLYEMLVGD 3 ( 522) LYEGHIEKDAREFIDKQVCGTPEYIAPEVI--FRQGYGK--P-VDWWAMGVVLYEFLVGC 4 ( 240) LYEGHIEKDAREFLDKQVCGTPEYIAPEVI--LRQG---YGKPVDWWAMGIILYEFLVGC 5 ( 202) ---GHIEKDAREFLDKQVCGTPEYIAPEVI--LRQG---YGKPVDWWAMGIILYEFLVGC // 0 ( 328) TPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI-CSRE-RRLGQNGIEDF 1 ( -) ............................................................ 2 ( 332) TPFYADSLVGTYSKIMDHKNSLCFPEDA-EISKHAKNLICAFL-TDRE-VRLGRNGVEEI 3 ( 577) VPFFGDTPEELFGQVVSDE--IMWPEGDEALPADAQDLITRLLRQSPL-DRLGTGGTHEV 4 ( 295) VPFFGDTPEELFGQVISDE--INWPEKDEAPPPDAQDLITLLL-RQNPLERLGTGGAYEV 5 ( 254) VPFFGDTPEELFGQVISDE--IVWPEGDEALPPDAQDLTSKLL-HQNPLERLGTGSAYEV // 0 ( 386) KKHAFFEG--LNWENIRNLEAPYIPDVSSPSDTSNFD-VDDDVLRNTEILPPGSHTGFSG 1 ( -) ............................................................ 2 ( 389) RQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDK-GDVETFPIPK--AFVG 3 ( 634) KQHPFFLA--LDWAGLLRHKAEFVPQLEAEDDTSYFD-TRSERYRHLGSEDDETNDEESS 4 ( 352) KQHRFFRS--LDWNSLLRQKAEFIPQLESEDDTSYFD-TRSEKYHHMET-EEEDDTNDED 5 ( 311) KQHPFFTG--LDWTGLLRQKAEFIPQLESEDDTSYFD....................... // 0 ( 443) LHLP-FIGFTFTTESCF-SDRGSLK--SIMQSNTLTK---DEDVQRDL----EH-SLQME 1 ( -) ............................................................ 2 ( 446) NQLP-FIGFTYYRENLLLSDSPSCRENDSIQSRKNEE---SQEIQKKLYTLEEHLSNEMQ 3 ( 691) TEIPQFSSCSHRFSKVY-SSSEFL---AVQPTPTFAERSFSEDREEGW----ER-S-EVD 4 ( 408) FNVE-IRQFSSCSHRFS-KVFSSID--RITQNSAEEK---EDSVDKTK----ST-TLP-- 5 ( -) ............................................................ // 0 ( 491) A---YERRIR----RLEQEKLELSRK--LQESTQTVQSLHGSSRALSNSNRDKEIKKLNE 1 ( -) ............................................................ 2 ( 502) AKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADH 3 ( 741) ----YGRRLS----ADIRLRSWTSSG--SSCQSSSSQPERGPSPSLLNT........... 4 ( 454) ----------------STETLSWSSE--YSE----MQQLSTSNSSDTESNRHK....... 5 ( -) ............................................................ // 0 ( 542) EIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQ----HRVVRQEKE---EL 1 ( -) ............................................................ 2 ( 562) EADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARL 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 595) HKQLVEAS---ERLKSQAKELKDAH---QQRKLALQ-EFSELNERMAELRAQKQKVSRQL 1 ( -) ............................................................ 2 ( 622) RKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEII 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 648) RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKER-----KLREHSENF 1 ( -) ............................................................ 2 ( 682) NDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSL 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 703) CKQMESELEALKVKQGGRGAGATLEHQQEI-SKIKSELEKKVLFYEEELVRREASHVLEV 1 ( -) ............................................................ 2 ( 742) -EQEEAEHKATKARLADKNK--IYESIEEAKSEAMKEMEKKLL--EERTLKQKVENLLLE 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 762) KNVKKEVHDSESHQLALQK--EILMLKDKLEKSKRERHNEMEEAVG----TIKD-KYERE 1 ( -) ............................................................ 2 ( 797) AEKRCSLLDCDLKQ-SQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 815) RAMLFDEN-KKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQW 1 ( 1) ...............................QLEEEVKDLADKKESVAHWEAQITEIIQW 2 ( 856) QVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDA----------DGQMKEL--- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 874) VSDEKDARGYLQALASKMTEEL--EALRSSSLGSRTLDPLWKVRRSQKLDMSARLELQ-S 1 ( 30) VSDEKDARGYLQALASKMTEEL--EALRNSSLGTRATDMPWKMRRFAKLDMSARLELQ-S 2 ( 903) -QDQLEAEQYFSTLYKTQVRELKEECEEKTKLG-KELQQKKQELQDERDSLAAQLEITLT 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 931) ALEAEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTG 1 ( 87) ALDAEIRAKQAIQEELNKVKASNIITECKLKDSEKKNLELLSEIEQLIKDTEE-LRSEKG 2 ( 961) KADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTS 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 991) LKLPDFQDSIFEYFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARP 1 ( 146) IEHQDSQHSFLAFLNTPTDALD-QFETVDST------PLSVHTPTL------------RK 2 ( 1021) -----------DVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERT 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1051) PQRPSAVPLPTTQALALAGPKPKAHQFSIKSFSSPTQCSHCT--SLMVGLIRQ--GYACE 1 ( 187) KGCPGSTGFP---------PKRKTHQFFVKSFTTPTKCHQCT--SLMVGLIRQ--GCSCE 2 ( 1070) LKTQAVNKL--AEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKE 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1107) VCSFACHVS--------------CKDGAPQVCPIPPEQSKRPLGVD---VQRGIGTA--- 1 ( 234) VCGFSCHIT--------------CVNKAPTTCPVPPEQTKGPLGID---PQKGIGTA--- 2 ( 1128) LNEMQAQIAEESQIRIELQMTLDSKDS--DIEQLRSQLQALHIGLDSSSIGSGPGDAEAD 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1147) -------YKGHVKVPKPTGVKK-GWQRAYAVVCDCKLFLYDLPEGK-STQPGVIASQVLD 1 ( 274) -------YEGHVRIPKPAGVKK-GWQRALAIVCDFKLFLYDIAEGK-ASQPSVVISQVID 2 ( 1186) DGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYM----VLD 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1198) LRDDEFSVSSVLASDVIHATRRDIPCIFRVTASLLGAPSKTSSLLILTENENEKKKWVGI 1 ( 325) MRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSILMLADTENEKNKWVGV 2 ( 1242) I-DKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPV--EPVGEKSNYI.. 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1258) LEGLQSILHKNRLRNQVVHVPLEAYDSSLPLIKAILTAAIVDADRIAVGLEEGLYVIEVT 1 ( 385) LSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIIDHERIALGNEEGLFVVHVT 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1318) RDVIVRAADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSLDGAEGSFDIKLPETKGC 1 ( 445) KDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPMSALDGRETDF-YKLSETKGC 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1378) QLMATATLKRNSGTCLFVAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDRLCV 1 ( 504) QTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKFKEIQVPYNVQWMAIFSEQLCV 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1438) GYPSGFCLLSIQGDGQPLNLVNPNDPSLAFLSQQSFDALCAVELESEEYLLCFSHMGLYV 1 ( 564) GFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMDAICAVEISSKEYLLCFNSIGIYT 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1498) DPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNS 1 ( 624) DCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENAVDIFDVNSMEWIQTLPLKKVRPLNN 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1558) EGTLNLLNCEPPRLIYFKSKFS-GAVLNVPDTSDNSKKQMLRT-RSKRRFVFKVPEEERL 1 ( 684) EGSLNLLGLETIRLIYFKNKMAEGDELVVPETSDNSRKQMVRNINNKRRYSFRVPEEERM 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1616) QQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVP-PSQEERPG--PA 1 ( 744) QQRREMLRDPEMRNKLISNPTNFNHIAHMGPGDGIQILKDLPMPGFPYPSPHHHSGLISS 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1673) PTNLAR-------------QPPSRNKPY-------------------------------I 1 ( 804) PINFEHIYHMTVNSAEKFLSPDSINPEYSPSLRSVPGTPSFMTLRNPRPQESRTVFSGSV 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1689) SWPS----------------------------------SGGSEPSVTVPLRSMSD----- 1 ( 864) SIPSITKSRPEPGRSMSASSGLSARSSAQNGSALKREFSGGSYSAKRQPMPSPSEGSLSS 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1710) ---------PDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQ-LPLEGLEQPACD 1 ( 924) GGMDQGSDAPARDFDKE-DSDSPRHSTASNSSNLSSPPSPVSPRKTKSLSLESTDRGSWD 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1760) T 1 ( -) . 2 ( -) . 3 ( -) . 4 ( -) . 5 ( -) . //