# 0 KIAA1319, 1208 aa # 1 KIAA1749 (1047 aa) # 2 KIAA0866 (1984 aa) # 3 KIAA2034 (1571 aa) # 4 KIAA1512 (2010 aa) # 5 KIAA1052 (1456 aa) // exp sw-scr id% from to 1 5.8e-34 1671 33.2 69 1024 2 3.7e-15 897 27.6 1127 1972 3 5.3e-14 815 26.0 644 1556 4 5.2e-09 623 24.2 1000 2003 5 1.2e-05 469 24.6 291 1240 // 0 ( 1) GLLLFMEQAPNMAEPRGPVDHGVQIRFITEPVSGAEMGTLRRGGRRPAKDARASTYGVAV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) RVQGIAGQPFVVLNSGEKGGDSFGVQIKGANDQGASGALSSDLELPENPYSQVKGFPAPS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 121) QSSTSDEEPGAYWNGKLLRSHSQASLAGPGPVDPSNRSNSMLELAPKVASPGSTIDTAPL 1 ( 69) ................................DNVNRHENR-RYIPFLPGTGRDIDTGSI 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 181) SSVDSLINKFDSQLGGQA-RGRTGRRTRMLPPEQRKRSKSLDSRLPRDTFEERERQSTNH 1 ( 96) PGVDQLIEKFDQKPGLQR-RGRSGKRNRI-NPDDRKRSRSVDSAFPFGL------QGNSE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1000) ...............................................ERLEDEEEVNADL 5 ( 291) ..........DSSLSSAVGKGRQGSGARPGLPEKEENEKS-EPKICRNLV---------- // 0 ( 240) WTSSTKYDNHVGTSKQ----PAQSQNLSPLSGFSRSRQTQDWVLQSFEE-PRR--SAQDP 1 ( 148) YL--IEFSRNLGKSSEHLLRPSQVCPQRPLSQERRGKQS---VGRTFAK-LQG--AAHGA 2 ( -) ............................................................ 3 ( 644) ............................................QELEKLKRR--LDGES 4 ( 1013) AARRRKLEDECTELKK----DIDDLELTLAKAEKEKQATENKVKNLTEE---M--AALDE 5 ( 330) ---TPKADP---TGSE----PAKA---------SEKEAPEDTVDAGEEG-SRREEAAKEP // 0 ( 293) TMLQFKSTPDLLRDQQEAAPPG-SV-DHMKATIYGILREGSSES----ET--SVRRKVSL 1 ( 200) SCAH--SRP----------PQP-NI-D-------GKVLETEGSQ----ES--TVIRAPSL 2 ( -) ............................................................ 3 ( 658) SELQEQMVEQQQRAEELRAQLGRKE-EELQAALARAEDEGGARA----QLLKSLREAQAA 4 ( 1064) SVARLTKEKKALQEAHQQAL-G-DL-QAEEDRV-SALTKAKLRL----EQ--QVE-DLEC 5 ( 370) K----KKASALEEGSSDASQEL-EISEHMKEPQLSDSIASDPKSFHGLDF--GFRSRISE // 0 ( 345) VLEKMQPLVMVSSGSTKAVAGQGELTRK----VEELQRKLDEEVKK-------RQK-LEP 1 ( 233) ----------------------GAQSKK----EEEVKTATATLMLQ-------NRA-AAT 2 ( 1127) .......................ELEGH----ISDLQEDLDSERAA-------RNK-AEK 3 ( 713) LAEAQEDLESERVARTKAEKQRRDLGEE----LEALRGELEDTLDSTNAQQELRSK-REQ 4 ( 1113) SLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKK-------KDS--EL 5 ( 423) HLLDVDVLSPVLGGACRQ-AQQPLGIED----KDDSQSSQDELQSK-------QSKGLEE // 0 ( 393) SQVGLERQL--EE-KTE-ECSR-LQELLERRKG-EAQ-QSNKELQNMKRLLDQGEDLRHG 1 ( 259) SPDSGAKKI--SV-KTF-PSA-----------S-NTQ-ATPDLLKGQQELTQQTNE---- 2 ( 1152) QKRDLGEEL--EALKTE-LEDT-LDSTATQQEL-RAK-R-EQEVTVLKKALDE-ETRSH- 3 ( 768) EVTELKKTL--EE-ETRIHEAA-VQEL-RQRHG-QALGELAEQLEQARRGKGAWEKTRLA 4 ( 1164) SQLSL--RV--ED-EQL-LGAQ-MQKKIKELQA-RAE-ELEEELEAERAARARVEKQRAE 5 ( 471) RYHRLSPPLPHEE-RAQ-SPPRSLATEEEPPQGPEGQ-PEWKEAEEL------GED---- // 0 ( 446) LETQVMELQNKLKHVQGPEPA-KEVLLKDL-LETRELLEEVLEGKQ-RVE--EQLRLRER 1 ( 298) -ETAKQILYNYLK--EGSTDN-DDA--------TKRKVNLVFEKIQ-T--------LKSR 2 ( 1203) -EAQVQEMRQK--HAQAVE-------------ELTEQLEQFKRAKA-NLD--KNKQTLEK 3 ( 822) LEAEVSELRAELSSLQTARQE-GEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 4 ( 1215) AARELEELSERLEEAGGASAGQREGCRKRE-AELGRLRRELEEAAL-RHE--ATVAALRR 5 ( 518) -SAASLSLQLSLQREQAPSPP-AAC--EKG-KEQHSQAEELGPGQE-EAE--DP---EEK // 0 ( 501) ELTALKGALKEEVASR---DQEV--EHVRQQYQR---DTEQLRRSMQDATQDHAVLEAER 1 ( 337) AAGSAQG--NNQACNS---TSEV--KDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEER 2 ( 1244) ENADLAGELRV-LGQA---KQEV--EHKKKKLEA---QVQELQSKCSDGERARAELNDKV 3 ( 881) ELENVSGALNEAESKTIRLSKEL--SSTEAQLH----DAQEL---LQEETRAKLALGSRV 4 ( 1271) KQAEGAAELGEQVDS-------L--QRVRQKLEK---EKSELRMEVDDLAANVETLTRAK 5 ( 567) VAVSPTPPVSPEVRST---EPVAPPEQLSEAALK---AMEEAVAQVLEQDQRH-LLESKQ // 0 ( 553) QKMSALVR---GLQRELE----ETS---EETGHWQSMFQKNKEDLRA-TKQEL------L 1 ( 390) ERMRANLE---ELRSQHN----EKV---EENSTLQQRLEESEGELRK-NLEEL------F 2 ( 1295) HKLQNEVESVTGMLNEAEGKAIKLA---KDVASLSSQLQDTQELLQEETRQKLNVSTKLR 3 ( 932) RAMEAEAA---GLREQLE----EEA----------AARERAGRELQT-AQAQL------S 4 ( 1319) ASAEKLCR---TYEDQLS----EAKIKVEELQRQLADASTQRGRLQT-ESGEL------S 5 ( 620) EKMQQLRE---KLCQEEE----EEI---LRL-HQQ------KEQSLS-SLRER------L // 0 ( 596) QLRMEKEE--MEEE---LG-------EKIEV---LQRELEQ-ARASAGDTRQ-------- 1 ( 433) QVKMEREQ--HQTEIRDLQ-------DQLSE---MHDELDS-AKRS--EDRE-------- 2 ( 1352) QLEEERNS--LQDQ---LD-------EEMEAKQNLERHIST-LNIQLSDSKKKLQDFAST 3 ( 968) EWRRRQEE-----E---AG-------A-LEA---G----EE-ARRRA--ARE-------- 4 ( 1365) RLLEEKEC--LISQ---LSRGKALAAQSLEE---LRRQLEEESKAKSALAHA-------- 5 ( 656) QKAIEEEEARMREE---ES-------QRLSW---LRAQVQS-S--TQADEDQ-------- // 0 ( 632) VEVLKKE--LLRTQ-EELKELQ-AERQ------SQEVA---------GRHRDR---ELE- 1 ( 470) KGALIEE--LLQAK-QDLQDLL-IAKE------EQEDL---------LRKRER---ELT- 2 ( 1399) VEALEEG--KKRFQ-KEIENLT-QQYE------EKAAA---------YDKLEKTKNRLQ- 3 ( 994) AEALTQR--LAEKT-ETVDRLE-RGRRRL----QQELD---------DATMDL---EQQ- 4 ( 1409) VQALRHDCDLLREQHEEEAEAQ-AELQRLLSKANAEVAQWRSKYEADAIQRTE---ELEE 5 ( 692) IRAEQEAS-LQKLR-EELESQQKAERA------SLE-------------QKNR---QML- // 0 ( 669) --KQLAVLRVE-ADRGRELEEQNLQ-LQKTLQQLRQDCEEASKA----KMV-------AE 1 ( 507) --ALKGALKEEVSSHDQEMDKLKEQ-YDAELQALRESVEEATKN----VEV-------LA 2 ( 1439) --QELDDLVVD-LDNQRQLVSNLEK-KQRKFDQLLAEEKNISSKYADERDR-------AE 3 ( 1033) --RQLV----------STLEKKQRK-FDQLLAEEKAAVLRAVEE----RER-------AE 4 ( 1465) AKKKLALRLQE-AEEGVEAANAKCSSLEKAKLRLQTESEDVTLE----LER-------AT 5 ( 727) --EQLKE-EIE-ASEKSEQAALNAA-KEKALQQLREQLEGERKE----AVATLEKEHSAE // 0 ( 714) AE---ATVLGQRRAAVETT---LRETQEENDEFRRRILG-LEQQLKETRGL------VDG 1 ( 553) SR---SNTSEQDQAGTEMR---VKLLQEENEKLQGRSEE-LERRVAQLQRQ------IED 2 ( 1488) AE---AREKETKALSLARA---LEEALEAKEELERTNKM-LKAEMEDLVSS------KDD 3 ( 1069) AE---GREREARALSLTRA---LEEEQEAREELERQNRA-LRAELEALLSS------KDD 4 ( 1513) SA---AAALDKKQRHLERA---LEERRRQEEEMQRE----LEAAQRESRGLGTELFRLRH 5 ( 778) LERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYH------VAG // 0 ( 761) -G--E-AVEA------RLRDKLQR-LEAEKQQLEEALNASQEE----EGSLAAAK----R 1 ( 600) -L--K-GDEA------KAKETLKK-YEGEIRQLEEALVHARKE----EKEAVSAR----R 2 ( 1535) VG--K-NVHELEKSKRALETQMEE-MKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 3 ( 1116) VG--K-SVHELERAC-RVAEQAANDLRAQVTELEDELTAAEDA----KLRLEVTV----Q 4 ( 1563) -GHEE-ALEALE----TLKRENKN-LQEEISDLTDQVSLSGKS----IQELEKTK----K 5 ( 832) -Y--EHELSS------LLREKRQE-VEGEHERRLDKMK--EEH----QQVMAKAR----E // 0 ( 802) ALE-------ARLEEAQRG--LA-----------RLGQEQQT-LNRALEEEGKQ-REVLR 1 ( 641) ALE-------NELEAAQGN--LS-----------QTTQEQKQ-LSEKLKEESEQ-KEQLR 2 ( 1591) DLQ-------ARDEQNEEK--RR-----------QLQRQLHE-YETELEDERKQ-RALAA 3 ( 1164) ALK-------TQHERDLQG--RD-----------EAGEERRRQLAKQLRDAEVE-RDEER 4 ( 1608) ALEGEKSEIQAALEEAEGA--LELEETKTLRIQLELSQVKAE-VDRKLAEKDEE-CANLR 5 ( 872) QYE-------AE-ERKQRAELLG-----------HLTGELER-LQRAHERELETVRQEQH // 0 ( 840) RG--------KAELEEQKRLLDRTVDRLNKELE--------KIGEDSKQALQQ------L 1 ( 679) RL--------KNEMENERWHLGKTIEKLQKEMA--------DIVEASRTSTLE------L 2 ( 1629) AA--------KKKLEGDLKDLELQADSAIKGRE-----------EAIKQ-LRK------L 3 ( 1203) KQ--------RTLAVAARKKLEGELEELKAQMA--------SAGQGKEEAVKQ------L 4 ( 1664) RNHQRAVESLQASLDAETRARNEAL-RLKKKMEGDLNDLELQLGHATRQATEAQAATRLM 5 ( 912) KR--------LEDLRRRHREQERKLQDLELDLE--------TRAKDVKARLAL------L // 0 ( 878) QAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTA 1 ( 717) QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA 2 ( 1663) QAQMKDFQ----RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 3 ( 1241) RKMQAQMKE-LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 4 ( 1723) QAQLKE--EQAGRD--EEQRLAAELHEQAQALERRASLLAAELEELRAALE--QGERSRR 5 ( 950) EVQ-EETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHL---LQSNQQLREI- // 0 ( 938) RLDKELLAQRLQGLEQEAENKKRSQDDRA-RQLKGLEEKVSRLETELDEEKNTVELLTDR 1 ( 777) LTKRQLLEQTLKDLEYELEAKSHLKDDRS-RLVKQMEDKVSQLEMELEEERNNSDLLSER 2 ( 1719) DLEKEELAEELA---SSLSGRNALQDEKR-R----LEARIAQLEEELEEEQGNMEAMSDR 3 ( 1300) QQDRDEMADEVAN----GNLSKAAILEEK-RQLEG---RLGQLEEELEEEQSNSELLNDR 4 ( 1777) LAEQELLEAT------ERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEK 5 ( 1005) -LD-ELQARKLK-LESQV-------DLLQ-AQSQQLQKHFSSLEAEAQKKQHLLREVTVE // 0 ( 997) VNRGRDQVD-QLRTELMQERSARQDLECDKISLERQNKDLKT-RLASSE--GFQKP--S- 1 ( 836) ISRSREQME-QVRNELLQERAARQDLECDKISLERQNKDLKS-RIIHLE--GSYRS--S- 2 ( 1771) VRKATQQAE-QLSNELATERSTAQKNESARQQLERQNKELRS-KLHEME--GAVKS--KF 3 ( 1352) YRKLLLQVE-SLTTELSAERSFSAKAESGRQQLERQIQELRG-RLGEED--AGARARHK- 4 ( 1831) AKKAITDAA-MMAEELKKEQDTSAHLERMKKTLEQTVRELQA-RLEEAEQAALRGG--K- 5 ( 1054) ENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHN--VWHLL--S- // 0 ( 1050) -AS--LSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHV---ND 1 ( 889) -KEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSL---TD 2 ( 1825) KST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMA---EQ 3 ( 1407) -MT--IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVA---DQ 4 ( 1886) -KQ--VQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQD 5 ( 1109) -AE--GVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRH---ELA-----SAQEV----- // 0 ( 1104) QKDQL---SLRVKALKRQVDEAEEEIERLDGLRKKAQREV---EEQHEVNEQ-------L 1 ( 945) QKDQL---SLRLKAMKRQVEEAEEEIDRLESSKKKLQREL---EEQMDMNEH-------L 2 ( 1880) YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL---DEATESNEAMGREVNAL 3 ( 1461) LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL---EDVTESAES-------M 4 ( 1943) LVDKL---QSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAET-------Q 5 ( 1153) AKDPP---G--IKALEDMRKNLEKETRHLDEM-KSAMR------KGHNLLKK-------K // 0 ( 1151) QARIKSLEKD-SWRKA-----SRSAAESALKNEGLSSDEEFDSVYDPSSIASLLTESNLQ 1 ( 992) QGQLNSMKKDLRLKKL-----PSKVLDDMDDDDDLSTD...................... 2 ( 1937) KSKLRRGNET-SFVPS-----RRSGGRRVIENAD-GSEEETDT................. 3 ( 1511) NREVTTL-RN-RLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA-QPGS........... 4 ( 1993) ANKLRARTRD-A-----........................................... 5 ( 1194) EEKLNQLESS-LWEEA-----S---DEGTLGGSPTKKAVTFD-LSDMDSLSSESSES... // 0 ( 1205) TSSC 1 ( -) .... 2 ( -) .... 3 ( -) .... 4 ( -) .... 5 ( -) .... //