# 0 KIAA1334, 989 aa # 1 KIAA1561 (1416 aa) # 2 KIAA1981 (862 aa) # 3 KIAA1074 (1715 aa) # 4 KIAA2015 (996 aa) # 5 KIAA1223 (1089 aa) // exp sw-scr id% from to 1 2.3e-22 1238 27.2 1 1048 2 4.5e-17 933 29.0 33 843 3 1.7e-06 464 21.6 32 967 4 7.6e-06 490 21.0 10 994 5 2.2e-05 435 25.5 533 1078 // 0 ( 1) SFGR-LNALNMKSLKAKFRKS--DT---------------NEWNKNDDRL--LQAVENGD 1 ( 1) ..........MKSLKSRLRRQ--DVPGPASSGAAAASAHAADWNKYDDRL--MKAAERGD 2 ( 33) ........................S---------------QDWGKSDERL--LQAVENND 3 ( 32) ..........................................................GG 4 ( 10) SFGRRLGQALLSSMDQEYAGPGYDI---------------RDWELR--KI--HRAAIKGD 5 ( 533) ........................T---------------NEID-NDGRIPFILASQEGH // 0 ( 41) AEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHV-ECLRVMITHGVDVTAQDTTGHSAL 1 ( 47) VEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNL-ECLNAILIHGVDITTSDTAGRNAL 2 ( 52) APRVAALIARKGLVPTKLDPEGKSAFHLAAMRGAA-SCLEVMIAHGSNVMSTDGAGYNAL 3 ( 34) GEPGEGAYSQPGYHVRDRDL-GK--IHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTAL 4 ( 51) AAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRV-QVVTLLLHRRCQIDICDRLNRTPL 5 ( 553) YDCVQILLENK-SNIDQRGYDGRNALRVAALEGHR-DIVELLFSHGADVNCKDADGRPTL // 0 ( 100) HLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDL 1 ( 106) HLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDV 2 ( 111) HLAAKYGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDR 3 ( 91) HLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADV 4 ( 110) MKAVHSQEEACAIVLLECGANPNIKDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNK 5 ( 611) YILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADN // 0 ( 160) DGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGAD 1 ( 166) DGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGAD 2 ( 171) SGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGAQ 3 ( 151) HGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKAN 4 ( 170) EGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIR 5 ( 671) EKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGAD // 0 ( 220) LNLVDSLGYNALHYSKLSE-----NAGIQSLL------------------------L--- 1 ( 226) ISLLDALGHDSSYYARIGD-----NLDILTLLKTASENTNKGRELWKKGPSLQQRNL--- 2 ( 231) PGITDALGQDAAHYGAL--------AG-DKLI------------------------L--- 3 ( 211) VNAVDKLESSHQLISEYKEERIPKHSSQNSNS------------------------V--- 4 ( 230) ISSQDMFGQTAEDYALCSD-----LRSIRQQI------------------------LEHK 5 ( 731) PNHADQFGRTAMRVAAKNG-----HSQIIKLL------------------------E--- // 0 ( 248) -----SKISQDADLKTPT-------KP----KQ----HDQVS-----KISSER-----S- 1 ( 278) -----THMQDEVNVKSHQ-------RE----HQ----NIQDL-----EIENEDLKERLR- 2 ( 255) -----HLLQEAAQRPSPP-------SA----LT----EDDSG-----EASSQN-----SM 3 ( 244) -----DESSEDSLSRLSG-------KP----GV----DDSWP-----T-SDDE-----D- 4 ( 261) NKMLKNHLRNDNQETAAM-------KPANLKKR----KERAKAEHNLKVASEE-----K- 5 ( 759) -----KYGASSLNGCSPSPVHTMEQKP----LQSLSSKVQSL-----TIKSNS-----S- // 0 ( 277) ------GTPKKRKAPPP----PISPTQLS---DVSSPRSITSTP---LSGKESVFF---A 1 ( 312) ------KIQQEQRILLD----KVNGLQLQLNEEVMVADDLESER---EKLKSLLAA---K 2 ( 285) SSHGKQGAPKKRKAPPP----PASIPMPD---DRDAYEEIVR-----LRQERGRLL---- 3 ( 272) ------LNFDTKNVPKP----SLAKLMTA---SQQSRKNLEATYGTVRTGNRTLFEDRDS 4 ( 304) ------QERLQRSENKQ----P-QDSQ-S---YGKKKDAMYGNF---MLKKDIAML---K 5 ( 799) ------GSTGGGDMQPSLRGLPNGPTHA-----FSSPSESPDST---VDRQKSSLS---N // 0 ( 318) EPPFKAEISSIRENKDRLSD--STTGADSLLDIS-SEADQ-QD--LLS--LL---QAKVA 1 ( 356) EKQHEESLRTIEALKNRFKY--FES--DHLGSGS-HFSNR-KEDMLLK--QG---QMYMA 2 ( 329) -----QKIRGLEQHKEQRQQ--ESPEASSLHILE-RQVQELQQ--LLV--ER---QEEKE 3 ( 319) DSQDEVVVESLPTTSIKVQC--FSHPTYQSPDLL-PKPSH-KS--LANPGLM---KEEPT 4 ( 343) EELYAIKNDSLRKEKKYIQEIKSITEINANFEKS-VRLNE-KM--ITK--TVARYSQQLN 5 ( 842) NSLKSSKNSSLRTTSSTATA--QTVPIDSFHNLSFTEQIQ-QH--SLP--RS---RSR-Q // 0 ( 367) SLTLHNKELQDKLQAKSP-KEAEAD--LSF-DSYH-STQTDLGPSLGKPG---ET---SP 1 ( 405) DSQCTSPGIPAHMQSRSMLRPLELS--LPS-QTSY-SENEILKKELEAMRTFCES---AK 2 ( 374) SLGREVESLQSRLSLLEN-ERENTS--YDV-TTLQ-DEEGEL-PDL--PG---AE---VL 3 ( 370) KPGIAKKENGIDIIESAP-LEQTNNDNLTYVDEVHKNNRSDMMSALGLGQ---EEDIESP 4 ( 397) DLKAENARLNSELEKEKH-NKERLE--AEV-ESLH-SS---LATAINEYN---EI---V- 5 ( 891) SIVSPSSTTQSLGQSHNS-PSSEFE--WS-----------QVKPSL-KST---KA---SK // 0 ( 416) PDSKSS----PSVLIHSLGKSTT----------D-N-DVRI--QQLQEILQ-------DL 1 ( 458) QDRLKL----QNELAHKVAECKALALECERVKED-S-DEQI--KQLEDALK-------DV 2 ( 420) LSRQLS----PSAQEH-LASLQE----------Q-V-AVLT--RQNQELME-------KV 3 ( 426) WDSESISENFPQKYVDPLAGAAD----------G-K-EKNIGNEQAEDVFYIPSCMSGSR 4 ( 442) -ERKDL----ELVLWRADDVSRH----------E-KMGSNI--SQLTDKNE-------LL 5 ( 930) -GGKSE----NSAKSGSAGKKAK----------QSN-SSQP--KVLEYEMT-------QF // 0 ( 451) QKR----LESSEAERK-QLQV-ELQSRRAELVCLNNT-----EISENSSD-LSQ---KLK 1 ( 503) QKR----MYESEGKVK-QMQT-HFLALKEHLTSEAAS-----GNHRLTEE-LKD---QLK 2 ( 454) QI-----LENFEKDET-QMEV-EALAEVIPLALYDSLRAEFDQLRRQHAE-ALQ---ALR 3 ( 474) NFK----MAKLEDTRNVGMPVAHMESPERYLHLKPTI-----EMKDSVPN-KAG---GMK 4 ( 477) TEQ----VHKARVKFN-TLKG-KLRETRDALRE-KTL-----ALGSVQLD-LRQAQHRIK 5 ( 965) DRRGPIAKSGTAAPPK-QMPA-ESQCKI--MIPSAQQ-----EIGRSQQQFLIH---QQS // 0 ( 496) ETQ-SK---YEEA-M----KEV-LSVQK------QMKL-GL-VS-PE-SMDNYSHF---- 1 ( 548) DLK-VK---YEGA-S----AEV-GKLRN------QIKQ-NE-MI-VE-EFKR-------- 2 ( 503) QQE-TREVPREEG-AACGESEV-AGATATKNGPTHMELNGS-VA-PE-TKVNGAETIDEE 3 ( 521) DVQTSK---AAEH-D----LEV-ASEEE------QERE-GS-EN-NQPQVEEERKK---- 4 ( 524) EMK-QM---HPNGEA----KES-QSIGK------QNSL-EERIR-QQ-ELENLLLE---- 5 ( 1013) GEQ-KK---RNGI-M----TNPNYHLQSN-----QVFL-GR-VSVPR-TMQDRGHQ---- // 0 ( 532) ------HELR---VTEEE-------INVLKQDLQNA----LEE--SERN----KEKVRE- 1 ( 580) ------DEGK---LIEEN--------KRLQKELSMC----EME--REKK----GRKVTE- 2 ( 557) AAGDETMEAR---TMEAE-------ATGAKATGAEATGAKVTE--TKPT----GAEVRE- 3 ( 559) ------HRNN---EMEVS-------ANIHDGATDDA----EDD--DDDDGLIQKRKSGE- 4 ( 562) ------RQLE---DARKEGDNKEIVINIHRDCLENG----KEDLLEERN----KELMKEY 5 ( 1052) ------EVLEGYPSSETE-------LS-LKQALKLQ----IEG--SD............. // 0 ( 565) --LEEKLV--ER-EKG---TVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEE 1 ( 612) --MEGQAK--EL-SAK---LALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 2 ( 600) --ME--TT--EE-EAN---METKPTGAQATDTETTG---VEAMGVEAT-----KTKAEEA 3 ( 596) --TDHQQF--PRKENK---EYASGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGG 4 ( 605) NYLKEKLLQCEK-EKAEREVIVREFQEELVDHLKTF-SISESPLEGTSHCHINLNETWTS 5 ( -) ............................................................ // 0 ( 617) IMKLK---DTLKSQMTQEAS-DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELED-Y 1 ( 664) IRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVY 2 ( 642) EMQAY---GVGAGQAEPPVT-GTT-NMEATGSRATGMEATGVSATGVENPGVEATVPG-I 3 ( 649) LLQVD---D--DSSLSEIDE-DEGRPTKKTSN----EKNKVKNQIQSM-----DDVDD-L 4 ( 663) KKKL--------FQVEIQPE-EKHEEFRK-LFELISLLNYTADQIRKKNRELEEEATG-Y 5 ( -) ............................................................ // 0 ( 672) RKRKSLED----VTAE----YI-------HKAEHE---KL--MQLTNVSRAKAEDALSEM 1 ( 724) LDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHD---AI--IDDLNRKLLDVTQKYTEK 2 ( 696) SAGPILHP----GAAE----AS-------EKLQVELETRI--RGLEEALRQREREAAAEL 3 ( 693) TQSSETAS----EDCE----LP-------HSS-YK---NF--MLLIEQLGMECKDSVSLL 4 ( 712) K--KCLE-----MTIN----ML-------NAFANE---DFNCHGDLNTDQLKMDILFKKL 5 ( -) ............................................................ // 0 ( 712) KSQYSK---VLNE-LTQLK-QLVDAQKENSVSIT---EHLQVITT------LRTAAKEME 1 ( 779) KLEMEK---LLLE-NDSLS-KDVSRLETVFVPPE---KHEKEIIA------LKSNIVELK 2 ( 739) EAALGKCEAAEAE-AGRLR-ERVREAEGSGASGGGGGDTTQLRAA------LEQAREDLR 3 ( 732) KIQDAA---LSCERLLELK-K----------------NHCELLTV---------KIKKME 4 ( 751) KQKFND---LVAE-KEAVSSECVNLAKDNEVLHQ---ELLSMRNVQEKCEKLEKDKKMLE 5 ( -) ............................................................ // 0 ( 758) EKISNLKE-HLA-SKEVEVAKLE--KQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLA 1 ( 825) KQLSELKK-KCG-EDQEKIHALT--SENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTN 2 ( 791) DRDSRLRELEAA-SACLDEARAS--RLLAEEEARGLRAELAQREEARLEQSRELEV.... 3 ( 763) DKVNVLQR-ELSETKEIK-SQLE--HQKVEWERELCSLRFSLNQEEEKRRNADT----LY 4 ( 804) EEVLNLKT-HME-KDMVELGKLQEYKSELDERAVQEIEKLEEIHLQK-QAEYEKQLEQLN 5 ( -) ............................................................ // 0 ( 814) SKLKESVKEKE----KVHSEVVQIRSEVSQVKREKE-NIQTL---LKSKEQEVNELLQKF 1 ( 881) RELLDVKKKFE----DINQEFVKIKDKNEILKRNLE-NTQNQ---IKAEYISLAEHEAKM 2 ( -) ............................................................ 3 ( 815) EKIREQLRRKE----E------QYRKEV-EVKQQLELSLQTLEMELRTVKSNLNQVVQER 4 ( 861) KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELE-EFKEV---FAAAVKANNSMSKKL 5 ( -) ............................................................ // 0 ( 866) QQAQEELAEMKRYSESSSKLEEDKDK---KINEMSK--EVTKLKEALNSLSQ---LSYST 1 ( 933) SSLSQS---MRKVQDSNAEILANYRKGQEEIVTLHA--EIKAQKKELDTIQECIKVKYAP 2 ( -) ............................................................ 3 ( 864) NDAQRQLSR-----EQNARMLQD-GI---LTNHLSKQKEIEMAQKKMN--SE---NSHSH 4 ( 917) MKSDKKIAVI------STKLFTEKQR---MKYFLST--LPTRPEPELPCVEN---LNSIE 5 ( -) ............................................................ // 0 ( 918) SSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQ 1 ( 988) IVSFEECER--KFKATEKELKDQLSE---QTQK----YSVSEEEVKKNKQEND--KLKKE 2 ( -) ............................................................ 3 ( 910) EEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQE--KEKKCFEDLKIVKEKNEDLQKTIKQ 4 ( 963) LNRKYIPKTAIRIPTSNPQTSNN---CKNFLTEVL......................... 5 ( -) ............................................................ // 0 ( 978) ILTMCKNQSQKK 1 ( 1037) IFTLQKDLRDKT 2 ( -) ............ 3 ( -) ............ 4 ( -) ............ 5 ( -) ............ //