# 0 KIAA1561, 1416 aa # 1 KIAA1334 (989 aa) # 2 KIAA1981 (862 aa) # 3 KIAA1074 (1715 aa) # 4 KIAA0004 (1307 aa) # 5 KIAA0373 (1540 aa) // exp sw-scr id% from to 1 9.6e-22 1238 27.2 10 988 2 2.7e-15 831 30.1 27 597 3 5.2e-07 634 22.0 23 1567 4 4.3e-06 538 22.5 232 1306 5 5e-06 502 21.9 183 1274 // 0 ( 1) MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYD-DRLMKAAERGDVEKVTSILA--KK 1 ( 10) MKSLKAKFRKSDT---------------NEWNKND-DRLLQAVENGDAEKVASLLG--KK 2 ( 27) .....................AAASFASQDWGKSD-ERLLQAVENNDAPRVAALIA--RK 3 ( 23) .....ARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKN 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 58) GVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCL 1 ( 52) GASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECI 2 ( 63) GLVPTKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSTDGAGYNALHLAAKYGHPQCL 3 ( 78) GLNDR--DKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCA 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 118) QKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQM 1 ( 112) RKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQN 2 ( 123) KQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQM 3 ( 136) TILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSG 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 178) SRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVE--VLIKNGADISLLDAL--- 1 ( 172) GHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVE--ALIKKGADLNLVDSL--- 2 ( 183) CHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVE--VLLQGGAQPGITDAL--- 3 ( 196) KKQQMVEFLIKKKANVNAVDKLESSHQLIS-EYKEERIPKHSSQNSNSVDESSEDSLSRL 4 ( 232) .......................................E--PLIHATTYIPLMD----- 5 ( -) ............................................................ // 0 ( 233) ----GHDSSYY-ARIGDNLDI---------LTLLKTAS-ENTNKGRELWK--KGPSLQQR 1 ( 227) ----GYNALHY-SKLSENAGI---------QSLL-------------------------- 2 ( 238) ----GQDAAHYGALAGDKL-I---------LHLLQEAA-QRPSPPSALTEDDSGEASSQN 3 ( 255) SGKPGVDDSWP-TSDDEDLNFDTKNVPKPSLAKLMTAS-QQSRKNLEATY--GTVRTGNR 4 ( 246) ----NADSSP----VVDKREV---------IDLLKPDQVEGIQKSGTKKL--KTETDKEN 5 ( -) ............................................................ // 0 ( 276) NL-----THMQDEV-NVKSH---QREHQNIQDLE---IENED-LK---ER---------- 1 ( 247) -L-----SKISQDA-DLKTP---TKPKQHDQVSK---ISSER------------------ 2 ( 283) SM-----SSHGKQG-APKKR---KAPPPPASIPM---PDDRD-AY---EE---------- 3 ( 311) TLFEDRDSDSQDEV-VVESL---PTTSIKVQCFSHPTYQSPD-LL---PKPSHKSLANPG 4 ( 287) AE-----VKFKDFLLSLKTMMFSEDEALCVVDLL---KEKSGVIQ---DA---------- 5 ( 183) .........LADSV-SKAVS---DADRQRILELE---KNEME-LKVEVSK---------- // 0 ( 310) LRKIQQEQRILLDKVNGLQL-------QLNEEV----MV-ADDL---ESEREKLKSLLAA 1 ( 276) -SGTPKKRKAPPPPISPTQL-------S--------------DV---SSPRSITSTPLSG 2 ( 317) IVRLRQERGRLLQKIRGLEQHKE----QRQQES----PE-ASSLHILERQVQELQQLLVE 3 ( 363) LMKEEPTKPGIAKKENGIDIIESAPLEQTNNDN----LTYVDEVH--KNNRSDMMSALGL 4 ( 326) LKKSSKGE--LTTLIHQLQE-------KDKLLA----AV-KEDA---AATKDRCKQLTQE 5 ( 216) LREISDIARRQVEILNAQQQ-------SRDKEVESLRMQ-LLDY---QAQSDE-KSLIA- // 0 ( 355) KEK------QHEESLRTIEALK-NRFKYFES--DHL-----GSGSHFSN-RK-EDMLLKQ 1 ( 311) KESVFFAEPPFKAEISSIRENK-DRLSDSTTGADSL-----LDISSEAD-QQ-D--LLSL 2 ( 368) RQE------EKESLGREVESLQ-SRLSLLEN--ERE-----NTSYDVTTLQD-EEGELPD 3 ( 417) GQE------EDIESPWDSESIS-ENFPQKYV--DPLAGAADGKEKNIGN-EQAEDVFYIP 4 ( 369) MMT------EKERSNVVITRMK-DRIGTLEK--EH---------NVFQN-KI-HVSYQET 5 ( 263) KLH------QHNVSLQLSEATALGKLESITS---KL-----QKMEAYNL-RL-EQKLDEK // 0 ( 399) --GQ-MY------MADSQCT-SPGIP-AHMQSR-SMLRPLELSLPSQTSYSENEILKKEL 1 ( 361) --LQ-AK------VASLTLH-NKELQ-DKLQAK-SP-KEAEADLSFDSYHSTQTDLGPSL 2 ( 413) LPGA-EV------LLSRQ-L-SPSAQ-EHLAS-------LQEQVAVLTR--QNQELMEKV 3 ( 467) --SC-MSGSRNFKMAKLEDTRNVGMPVAHMESP-ERYLHLKPTIEMKDSVPNKAGGMKDV 4 ( 409) --QQ-MQ------MKFQQ------VR-EQMEAEIAHLKQENGILRDAVSNTTNQLESKQS 5 ( 307) --EQALY------YARLEGR-NRAKH-LRQTIQ-SLRRQFSGALP----LAQQEKFSKTM // 0 ( 447) EAMRTFCESAKQD-RLKLQNELA-----HKVAECKALALECE-RVKEDSDEQ--IK-QLE 1 ( 408) GKP---GETSPPD-SKSSPSVLI-----HSLGKSTT-----------DNDVR--IQ-QLQ 2 ( 454) QILENF----EKD-ETQMEVE--------ALAEVIPLALY-D-SLRAEFDQL--RR-QHA 3 ( 523) QTSK----AAEHDLEVASEEEQE-----REGSENNQPQVEEE-RKKHRNNEMEVSA-NIH 4 ( 453) AELNKL----RQD-YARLVNELT-----EKTGK-----LQQE-EVQKKNAEQ--AATQLK 5 ( 352) IQL-------QND-KLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELIST--LK-DTK // 0 ( 497) DALKDVQKRMYESEG---KVKQMQTHFLALKE--------HLTSEAASGNHRLTEELKDQ 1 ( 445) EILQDLQKRLESSEA---ERKQLQVELQSRRA--------ELVCLNNTEISENSSDLSQK 2 ( 496) EALQ--------------ALRQQETREVPREE--------G----AACGESEVAGATATK 3 ( 572) DGATDDAEDDDDDDGLIQKRKSGETDHQQFPR--------KENKEYASGPALQMKEVKST 4 ( 495) VQLQEAERRWEEVQS---YIRKRTA------E--------H---EAAQ------------ 5 ( 401) GAQKVINWHMKIEEL---RLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQ // 0 ( 546) LKDLKVKYEGASAEV-GK---LRNQI-----KQ--NEMI--VEEFKR----DEG----KL 1 ( 494) LKETQSKYEEAMKEV-LS---VQKQM-----KL--GLVS--PESMDNYSHFHEL----RV 2 ( 530) NGPTHMELNGSVAP--------ETKV-----NG--AETI--DEEAAG----DE------- 3 ( 624) EKEKRTSKESVNSPVFGKASLLTGGL-----LQVDDDSS--LSEIDE----DEGRPTKKT 4 ( 523) -QDLQSKFVAKENEV-QS---LHSKL-----TD--TLVS--KQQLEQ----RLM----QL 5 ( 458) NKFHEERQMAWDQRE-VD---LERQLDIFDRQQ--NEILNAAQKFEE----ATG----SI // 0 ( 585) IE-EN-KRLQKEL-SM----------------CEME-REKKGRKVTEMEGQAKELSAKLA 1 ( 537) TE-EEINVLKQDL-QN----------------ALEE-SERNKEKVRELEEKLVEREKGTV 2 ( 562) TM-EA-RTMEAEA-TG----------------AKATGAEATGAKVTETKPTGAEV..... 3 ( 673) SN-EK-NKVKNQIQSMDDVDDLTQSSETASEDCELP-HSSYKNFMLLIEQLGMECKDSVS 4 ( 561) MESEQ-KRVNKEE-SL-----------------QMQ-VQDILEQNEALKAQIQQFHSQIA 5 ( 504) PD-PS-LPLPNQL-EI----------------ALRK-IKENIRIILETRATCKSLEEKLK // 0 ( 625) L------SIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSL-SEIRQLKRELENVKAK 1 ( 578) I------KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQ-EEIMKLK---DTLKSQ 2 ( -) ............................................................ 3 ( 730) LLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQREL-SETKEIKSQLEHQKVE 4 ( 601) A------QTSAS---VLAEELHKVIAEKDKQI----KQTEDSLASERDRLTSKEEELKD- 5 ( 544) E------KESALRLAEQNILSRDKVINELRLRLPATAEREKLI-AELG--RKEMEP-KSH // 0 ( 678) LAQHV--------KPEE--------HEQVKSRLEQKSGELGKKIT---ELTLKNQTLQKE 1 ( 628) MTQEA--------S-DE--------AEDMKEAMNRMIDELNKQVS---ELSQLYKEAQAE 2 ( -) ............................................................ 3 ( 789) WERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 4 ( 647) -IQNM--------NFLL--------KAEVQ-KLQALANEQAAAAH---ELEKMQQSVYVK 5 ( 594) HTLKI--------AHQT--------IANMQARLNQKE-EVLKKYQ---RLLEKAREEQRE // 0 ( 719) IEKVYLD-NKLLKEQA---HNLTIE----------MKNHYVPLKVSEDMKKSHDAIIDDL 1 ( 668) LED-YRK-RKSLED-------VTAE--------------YI-------HKAEHEKLMQLT 2 ( -) ............................................................ 3 ( 849) LRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHS 4 ( 686) DDKI-----RLLEEQL---QH---E----------ISNKMEEFKILNDQNKALKSEVQKL 5 ( 634) IVKKH-------EEDL---HIL---------------HHRLELQADSSLNKFKQTAWDLM // 0 ( 765) NRKLLDV-TQKYTEKKLEMEKLLLE-NDSLS-----KDVSRL-ETVFVPPEKHEKEIIAL 1 ( 698) NVSRAKA-EDALSEMKSQYSKVLNE-LTQLK-----QLVDAQ-KENSVSITEHLQVITTL 2 ( -) ............................................................ 3 ( 909) HEEEKDL-SHKNSMLQEEIAMLRLE-IDTIKNQNQEKEKKCF-EDLKIVKEKNEDLQKTI 4 ( 725) --QTLVS-EQPNKDVVEQMEKCIQE-KDEKL-----KTVEELLETGLIQVATKEEELNAI 5 ( 669) KQSPTPVPTNKHFIRLAEMEQTVAEQDDSLS-----SLLVKL-KKVSQDLER-QREITEL // 0 ( 817) KSNIVE-LKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKT-HEEVKMTLND 1 ( 750) RTAAKE-MEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSS-YEKLQSSLES 2 ( -) ............................................................ 3 ( 966) KQNEET-LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD 4 ( 776) RTENSS-LTKEVQDLKAK-QNDQVSFASLVEE---LKKVIHEKDGKIKS-VEE--LLEAE 5 ( 722) KVKEFENIKLQLQE------NHEDEVKKVKAEVEDLKYLLD------QS-QKESQCLKSE // 0 ( 875) TLAK--TNRELL-------DVKKKFED-INQEFVKIKDKNEILKRNLENTQN-QIKAEYI 1 ( 808) EVSV--LASKLK-------ESVKEKEK-VHSEVVQIRSEVSQVKREKENIQT-LLKSKEQ 2 ( -) ............................................................ 3 ( 1025) RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTES-KLNSLEI 4 ( 828) LLKV--ANKE------------KTVQD-LKQEIKALKE--EIGNVQLEKAQQLSITSKVQ 5 ( 769) LQAQ-------------------KEAN-SRAPTTTMRNLVERLKSQLALKEK-QQKALSR // 0 ( 924) -------SLAEH----EAKMSSLSQS---MRKVQDS--NAEILANYRKGQEEIVT----- 1 ( 857) -------EVNEL----LQKFQQAQEELAEMKRYSES--SSKLEEDKDK---KINE----- 2 ( -) ............................................................ 3 ( 1084) EFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQ 4 ( 871) -------ELQNL----LKGKEEQMNT---MKAVLEE--KEKDLANTGKWLQDLQE----- 5 ( 808) -------ALLEL----RAEMTAAAEE---RIISATS--QKEAHLNV----QQIVD----- // 0 ( 963) LHA-EIKAQKKELDTIQECIKVKYAPIVS----FEECER--KFKATEKELK--------- 1 ( 896) MSK-EVTKLKEALNSLS---QLSYSTSSS----KRQSQQLEALQQQVKQLQ--------- 2 ( -) ............................................................ 3 ( 1144) LQS-ENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQ--KLQA-ESEKQ--------- 4 ( 910) ENE-SLKAHVQEV--AQHNLK-EASSASQ----FEELEI--VLKEKENELKRLEAMLKER 5 ( 843) RHTRELKTQVEDLN--ENLLKLKEA-LKT----SKNREN--SLTDNLNDLN--------- // 0 ( 1007) -DQLSE---QTQK----YSVSEEEVKKNKQ---END--KLKKEIFT--LQKDLRDKTVLI 1 ( 939) -NQLAECKKQHQEVISVYRMHLLYAVQGQM---DEDVQKVLKQILT--MCKNQSQK.... 2 ( -) ............................................................ 3 ( 1191) -SLLLE---ERNK----ELISECNHLKERQYQYENE--KAEREVVVRQLQQELADTLKKQ 4 ( 960) ESDLSS---KTQL----LQDVQDENKLFKS---QIE--QLKQQNYQ--QASSFPPHEELL 5 ( 885) -NELQK---KQKA----YNKILREKEEIDQ---END--ELKRQIKR--LTSGLQGKPLTD // 0 ( 1052) EKS---HEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLV--EENAKQTSEILAVQNL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1241) SMS---EASLEVTSRYRINLEDETQDLKKKLGQIRN---QLQ--EAQDRHTEAVRCAEKM 4 ( 1006) KVI---SEREKEISGLWNELDS-LKDAVEHQRKKNNERQQQV--EAVELEAKEVL--KKL 5 ( 930) NKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNK // 0 ( 1107) LQKQHVPLEQVEA-LKKSLNGTIENL-----KEELKSMQRCYEKEQQTVTKL-------- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1293) -QDHKQKLEKDNAKLKVTVKKQMDKI-----EELQKNLLNANLSEDEK-EQL-------- 4 ( 1058) FPKVSVPSNL--S-YGEWLHGFEKKA-----KE---CMAGTSGSEEVKVLE--------- 5 ( 990) LKEKE---GEVFT-LTKQLN-TLKDLFAKADKEKL-TLQRKLKTTGMTVDQVLGIRALES // 0 ( 1153) HQLLENQKNSSVPLAE---HLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1338) KKLMELKQSLECNLDQ---EMKKNVELEREITGFKNLLKM----TRKKLNEYENGEFSFH 4 ( 1098) HKLKEADEMHTLLQLE---CEKYKSVLAETEGILQKLQRSVEQE-ENKW------KVKVD 5 ( 1044) EKELEELKKRNLDLENDILYMRAHQALPRD-SVVE-DLHLQNRYLQEKLHALEKQFSKDT // 0 ( 1210) NTKQALKKLET-----REVVDLSKYKATKS----DLETQISSLNE---KLANLNRKYEEV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1391) GD---LKTSQF-----EMDIQINKLKHKID----DLTAELETAGS---KCLHLDTKNQIL 4 ( 1148) ESHKTIKQMQ------------SSFTSSEQ----ELE-RLRSENK---DIENLRREREHL 5 ( 1102) YSKPSISGIESDDHCQREQ-ELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEM // 0 ( 1258) CEEVLHAK----KKEISAKDEKELLHFSIEQEI---KDQKERCDKSLTTI-TELQRR--- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1436) QEELLSMKTVQKKCEKLQKNKKKL-----EQEVINLRSHIERNMVELGQV-KQYKQE--- 4 ( 1188) EMELEKA---------------EMERSTYVTEV---RELKAQLNETLTKLRTEQNERQKV 5 ( 1161) CE-FLKKE----KAEV----QRKLGHVRGSGRS---GKTIPELEKTIGLM-KKVVEK--- // 0 ( 1307) ---IQESAKQIEAKDNKIT-ELLNDVERLKQALNG-LSQLT---YTSGNPTKRQS--QLI 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1487) ---IEERARQ------EIA-EKLKEVNLFLQA-QA-ASQENLEQFRENNFASMKS--QM- 4 ( 1230) AGDLHKAQQSLELIQSKIV-KAAGDTTVIEN--SD-VSPET---ESSEKETMSVSLNQTV 5 ( 1205) ---VQRENEQLKKASGILTSEKMANIEQENEKLKAELEKLK---AHLGH--------QLS // 0 ( 1357) DTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1532) ---ELRIKDLESELSKIKTSQED---FNKTELEKYKQLYLEE.................. 4 ( 1283) TQLQQLLQAVNQQLTK-EKEHYQVL................................... 5 ( 1251) MHYESKTKGTEKIIAENERLRKEL.................................... // 0 ( -) 1 ( -) 2 ( -) 3 ( -) 4 ( -) 5 ( -) //