# 0 KIAA1568, 1380 aa # 1 KIAA1132 (2092 aa) # 2 KIAA0230 (1496 aa) # 3 KIAA1496 (920 aa) # 4 KIAA1355 (1189 aa) # 5 KIAA0343 (1187 aa) // exp sw-scr id% from to 1 1.1e-15 892 27.5 443 1218 2 1.3e-15 757 30.5 234 711 3 2.9e-13 796 27.6 22 780 4 1.4e-09 602 26.0 34 760 5 5.1e-09 884 25.5 23 999 // 0 ( 1) VKMSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEH-PSDVIVSKGEPTTLNCK---A 1 ( 443) ............................EDGTPRIVSS-FSEKVVNPGEQFSLMCA---A 2 ( -) ............................................................ 3 ( 22) ........................................STVSVREGQGVVLLC----- 4 ( 34) ................................PEVV-----SVVGRAGESVVLGCDLLPP 5 ( 23) .RVPLILFLCQMISA-LEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCE---A // 0 ( 57) EGRPT-PTIE----WYKDGERVE--------TDKDDP-RSHRMLLPSGSLFFLRIVHGRR 1 ( 471) KGAPP-PTVT----WALDDEPIV--------RD-GSH-RTNQYTMSDGTTISHMNVTGPQ 2 ( -) ............................................................ 3 ( 37) -GPPP-HSGELSYAWIFN-EYPS--------FVEEDS-RRF-VSQETGHLYISKV----- 4 ( 57) AGRPPLHVIE----WLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQKGASL---QIEGLR 5 ( 78) KGKPP-PSFS----WTRNGTHFD--------IDKDPL-VTMK---PGTGTLIINIMSEGK // 0 ( 103) SKP-DEGSYVC-VA---RNYLGEAVSRNASLEVALLRDD---FR---------QNPT--- 1 ( 516) IR--DGGVYRC-TA---RNLVGSA-EYQARINV----------R---------GPPSIRA 2 ( 234) .....QAAAICEYP---RRIQGRSVATITPEELNCERPR---IT---------SEPQ--- 3 ( 79) -EPSDVGNYTC-VV---TSMVTNARVLGSPTPLVLRSDG---VMGEYEPKIEVQFPE--- 4 ( 110) VE--DQGWYEC-RVFFLDQHIPEDDFANGSW-VHLTVNSPPQFQ---------ETPP--- 5 ( 121) AET-YEGVYQC-TA---RNERGAAVSNNIVVRPSRSPLW---TK---------EKLE--- // 0 ( 143) --DVV-VAAGEPAILECQPPRGHPEPTIYWKK-DKVRIDDKEE-RISI-R--G--GKLMI 1 ( 550) MRNIT-AVAGRDTLINCRVI-GYPYYSIKWYK-DALLLPDNHR-QVVF-E--N--GTLKL 2 ( 271) --DAD-VTSGNTVYFTCRA-EGNPKPEIIWLR-NNNELSMKTDSRLNLLD--D--GTLMI 3 ( 128) --TLP-AAKGSTVKLECFA-LGNPIPQINWRRSDGLPFSSK----IKL-RKFS--GVLEI 4 ( 154) --AVLEVQELEPVTLRCVA-RGSPLPHVTWKL-RGKDLGQGQG-QVQV-Q--N--GTLRI 5 ( 161) --PIT-LQSGQSLVLPCRPPIGLPPPIIFWMD-NSFQRLPQSE-RVS--Q--GLNGDLYF // 0 ( 193) SNTRKS-DAGM-YTCVGT-NMVGE-RDSDPAELTVF------ERP-TFLRRPIN-QVVLE 1 ( 601) TDVQKGMDEGE-YLC--S-VLIQP-QLSISQSVHVA------VKV-PPLIQPFEFPPASI 2 ( 322) QNTQET-DQGI-YQCMAK-NVAGE-VKTQEVTLRYFGSP---ARP-TFVIQPQN-TEVLV 3 ( 177) PNFQQE-DAGS-YECIAE-NSRG--KNVARGRLTYY------AKP-HWVQLIKD-VEIAV 4 ( 204) RRVERG-SSGV-YTCQAS-STEGS-A-THATQLLVL------GPP-VIVVPPKN-STVNA 5 ( 212) SNVLPE-DTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGN-ASNKE // 0 ( 241) E---EAVEFRCQVQ-GDPQP-TVRWKKDD-ADL-------PRG-R-YDIKD-DY---TLR 1 ( 649) G---QLLYIPCVVSSGDMPI-RITWRKDG-QVI-------ISG-SGVTIES-KEFMSSLQ 2 ( 373) G---ESVTLECSAT-GHPPP-RISWTRGDRTPL-------PVDPR-VNITP-SG---GLY 3 ( 224) E---DSLYWECRAS-GKPKP-SYRWLKNG-AAL-------VLE-E-RTQIE-NG---ALT 4 ( 251) S---QDVSLACHAE-AYPANLTYSWFQDN-INVFHISRLQPRV-R-ILV---DG---SLR 5 ( 270) ELRGNVLSLECIAE-GLPTP-IIYWAKED-GML-------PKN-R-TVYKNFEK---TLQ // 0 ( 282) IKKTMSTDEGTYMCIAENRV-GKMEASATLTVRAP-PQFVVRPRDQIV-AQ-GRTVTFPC 1 ( 695) ISSVSLKHNGNYTCIASNAA-ATVSRERQLIVRVP-PRFVVQPNNQDG-IY-GKAGVLNC 2 ( 416) IQNVVQGDSGEYACSATNNI-DSVHATAFIIVQAL-PQFTVTPQDRVV-IE-GQTVDFQC 3 ( 265) ISNLSVTDSGMFQCIAENKH-GLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDC 4 ( 298) LLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYP-AQVTAMPPETPL-PI-GMPGVIRC 5 ( 315) IIHVSEADSGNYQCIAKNAL-GAIHHTISVRVKAA-PYWITAPQNLVL-SP-GEDGTLIC // 0 ( 338) ETKGNPQPAVF--WQK-EGSQNLL--FPNQ--PQQPNSRCSVSPTGDLTI-TNIQRSDAG 1 ( 751) SVDGYPPPKVM--WKHAKGSGN-----PQQYHPVPLTGRIQILPNSSLLI-RHVLEEDIG 2 ( 472) EAKGNPPPVIA--WTK-GGSQ------------LSVDRRHLVLSSGTLRI-SGVALHDQG 3 ( 324) KPRASPRALSS--WKK--GDVSV-----------QEHERISLLNDGGLKI-ANVTKADAG 4 ( 355) PVRANP-PLLFVSWTK-DGKALQLDKFPGW--SQ--------GTEGSLII-ALGNEDALG 5 ( 371) RANGNPKPRIS--WLT-NGVPIEI--APDD--P----SR---KIDGDTIIFSNVQERSSA // 0 ( 390) YYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAV--DGTAL-L-KCKATG 1 ( 803) YYLCQASNGVGTDISKSMF-----LTVKIPAMITSHP-NTTIAI--KGHAKEL-NCTARG 2 ( 516) QYECQAVNIIGSQKVVAHLTVQP----RVTPVFASIPSDTTVEV--GANVQ-L-PCSSQG 3 ( 368) TYTCMAENQFGKANGTTHLVVTE------PTRITLAPSNMDVSV--GESVI-L-PCQVQH 4 ( 402) EYSC---TPYNSLGTAGPSPVTRVLL-KAPPAFIERPKEEYFQE--VGREL-LIPCSAQG 5 ( 417) VYQCNASNEYGYLLANA---FVNVLAE--PPRILT-PANTLYQVIANRPAL-L-DCAFFG // 0 ( 446) DPL--PVISWLKEG----FTF-PGRD-PRATI--QEQG-----TLQIKNLRISDTGTYTC 1 ( 854) ERP--IIIRWEKGD----TVIDPDRV-MRYAIATKDNGDEVVSTLKLKPADRGDSVFFSC 2 ( 568) EPE--PAITWNKDG----VQV-T-ES-GKFHI--SPEG-----FLTINDVGPADAGRYEC 3 ( 418) DPLLDIIFTWYFNGALADFKK-DGSHFEKVGG--SSSG-----DLMIRNIQLKHSGKYVC 4 ( 455) DPP--PVVSWTKVG----RGL-QGQ----AQV--DSNS-----SLILRPLTKEAHGHWEC 5 ( 469) SPL--PTIEWFKGA----KGS-ALHE-DIYVL--HENG-----TLEIPVAQKDSTGTYTC // 0 ( 491) VATSSSGETSWSAVLDVTESGATISK-NYD----LSDLPGPPS-KPQVTDVTKNSVTLSW 1 ( 907) HAINSYGEDRGLIQLTVQEP------------------PDPP--ELEIREVKARSMNLRW 2 ( 612) VARNTIGSASVSMVLSVNVPD--VSR-NGDPFVATSIVEAIAT-VDRAINSTRTHLFDS- 3 ( 470) MV--QTGVDSVSSAADLIVRGS----------------PGPPE-NVKVDEITDTTAQLSW 4 ( 497) SASNAVARVATSTNVYVLGTSPHVVT-NVS----VVALP--------------KGANVSW 5 ( 514) VARNKLGMAKNEVHLEIKDATWIVKQPEYA----VVQRGSMVSFECKVKHDHTLSLTVLW // 0 ( 545) QPGT---PG----TL------PASAYI----IE-AFSQSV-SNSWQTVAN--HV---KTT 1 ( 947) TQRF---DG----NS------IITGFD----IE-YKNKSD-SWDFKQSTR--NI---SPT 2 ( 667) RPRS---PN----DLLALFRYPRDPYT----VEQARAGEIFERTLQLIQE--HV---QHG 3 ( 511) KEGK---DN----HS------PVISYS----IQ-ARTP-F-SVGWQTVTTVPEVIDGKTH 4 ( 538) EPGF---DG----GY------LQRFSVWYTPLA-KRPDRM-HHDWVSLAV--PV---GAA 5 ( 570) LKDNRELPSDERFTV------DKDHLV----VA-DVSDDD-SGTYTCVAN--------TT // 0 ( 581) LY--TVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQD----I-SPPAQGVDHRQVQ 1 ( 983) INQANIVDLHPASVYSIRMYSFNKIGRSEPSKELT-ISTEE----A-APDGPPMD----- 2 ( 711) L........................................................... 3 ( 551) TA--TVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEE----A-VPE---VPPSEVN 4 ( 578) HL--LVPGLQPHTQYQFSVLAQNKLG---SGPFSEIVLSAPEGLPT-TPAAPGLPPTEIP 5 ( 610) LD--SVSA----SAVLSVVA---------PTPTPAPV--YD----VPNPP--------FD // 0 ( 634) KEL----GDVLVRLHNPVVLTPTTVQVTWTV-DR---Q-PQFIQ-----GYRVMYRQTS- 1 ( 1032) -----------VTLQ-PV--TSQSIQVTWKA-PKKELQ-NGVIR-----GYQIGYRENSP 2 ( -) ............................................................ 3 ( 601) GGG----G------------SRSELVITW---DP---V-PEELQNGEGFGYVVAFRPLG- 4 ( 632) PPLSPPRGLVAVR-------TPRGVLLHWDP-PE---LVPKRLD-----GY-VL----E- 5 ( 641) LEL----TDQLDK----------SVQLSWTPGDD---N-NSPIT-----KFIIEYED--- // 0 ( 679) GLQATSSWQNLDAKVPTERSAVLV-N--LKKGVTYEIKVRPYFNEFQGMDSE-SKTVRTT 1 ( 1071) GSNGQYSIVEMKATGDSE-VYTLD-N--LKKFAQYGVVVQAFNRAGTGPSSS-EINATTL 2 ( -) ............................................................ 3 ( 637) ----VTTWIQTVVTSPDTPRYVFR-NESIVPYSPYEVKVGVYNNKGEGPFSP-VTTVFSA 4 ( 670) GRQGSQGWEVLDPAVAGTETELLVPG--LIKDVLYEFRLVAFAGSFVSDPSN-TANVSTS 5 ( 675) AMHKPGLWHH-QTEVSGTQTTAQL-N--LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTK // 0 ( 735) --EEAPSA---P---PQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGN 1 ( 1126) --EDVPSQ---P---PENVRALSI---TSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYV 2 ( -) ............................................................ 3 ( 691) --EEEPTV---A---PSQVSA---NSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGG 4 ( 727) GLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAV.......................... 5 ( 731) --ASEPDK---N---PTAVEGL--GS-EPDNLVITWKPLNGFESNGPGLQYKVS-W-RQK // 0 ( 785) ETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP-IIIGRRNE--V 1 ( 1175) DGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRS................ 2 ( -) ............................................................ 3 ( 740) KEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAG................... 4 ( -) ............................................................ 5 ( 778) DGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFA----PEPAVVMGHSGEDLP // 0 ( 842) VITENN---NSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWR-----RKKRKGLS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 834) MVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGH----LQGYRIY-YWKTQSSSKRNRRHIE // 0 ( 894) NYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGN-FGR 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 889) KKILTFQ----GSKTHGMLPGL----EPF-----SHYTLNVRVVNGKGEGPASPDRVFNT // 0 ( 953) GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 936) PEGVPSAPS---------SLKIVNPTLDSLT-LEWDPPSHPNGILTEYTLKYQPINSTHE // 0 ( 1013) LA--VDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGST 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 986) LGPLVDLKIPANKT.............................................. // 0 ( 1071) WANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDR 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1131) VPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1191) SNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1251) DSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREG 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1311) MTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1371) NSQGQFTGEL 1 ( -) .......... 2 ( -) .......... 3 ( -) .......... 4 ( -) .......... 5 ( -) .......... //