# 0 KIAA1633, 1852 aa # 1 KIAA0454 (2296 aa) # 2 KIAA0866 (1984 aa) # 3 KIAA0477 (1148 aa) # 4 KIAA0949 (1559 aa) // exp sw-scr id% from to 1 5.3e-11 1251 24.8 123 2295 2 4.9e-05 375 21.8 856 1941 3 0.0001 374 21.3 357 1147 4 0.00021 340 22.6 171 769 // 0 ( 1) TRAGVEGAGTWGARRVAIAGGTSGAAATDTNAVATSVSMMDLVLEEDVTVPGTLSGCSGL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 61) VPSVPDDLDGINPNAGLGNGLLPNVSEETVSPTRARNMKDFENQITELKKENFNLKLRIY 1 ( 123) .................................QTQALRDFEKHLNDLKKENFSLKLRIY 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 171) ...........................................EYAKLEKINAEQQLKIQ // 0 ( 121) FLEERMQQEFHGPTE--HIYKTNIELKVEVESLKRELQEREQLLIKASKAV-ESLAEAGG 1 ( 150) FLEERMQQKYEASRE--DIYKRNIELKVEVESLKRELQDKKQHLDKTWADV-ENLNSQNE 2 ( 856) ...........................................LLQVTRQE-EEM-QAKE 3 ( -) ............................................................ 4 ( 188) ELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNRED----SSEGIRKKLVEA-- // 0 ( 178) SEIQRVKEDARKKVQQVEDLLTKRILLLE-KDVTAAQAELEKAFAGTETEKALRLRLESK 1 ( 207) AELRRQFEERQQETEHVYELLENKIQLLQ-EESRLAKNEAARMAALVEAEKECNLELSEK 2 ( 871) DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEE-MRVRLAAK 3 ( -) ............................................................ 4 ( 242) EELEEKHREAQVSAQHLEVHLKQKEQHYE-EKIKVLDNQIKKDLADKETLENMMQRHEEE // 0 ( 237) LSEMKK-MHE---GDLA----MALVLDEKDRLIEE--L---KLSLKSKEALIQCLKEEKS 1 ( 266) LKGVTK-NWEDVPGDQVKPDQYTEALAQRDKRIEE--L---NQSLAAQERLVEQLSREKQ 2 ( 929) KQELEEILHE---ME-------ARLEEEEDR---G--Q---QLQAERKKMAQQMLDLEE- 3 ( 357) ...LKP-LYK---TPVS----YPLELSDLQELWDD--LCEDYLPLRVQPMTEELLKQQK- 4 ( 301) AHEKGK-ILS---EQKA----MINAMDSKIRSLEQRIV---ELSEANKLAANSSLFTQRN // 0 ( 284) QMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQ-----KERNS----FQERIQA-- 1 ( 320) QLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQ-----SVSDSHLAELQEKIQQTE 2 ( 970) QLEEEEAARQKLQLEKVTAEAKIKKL-EDEILVMDDQNNKLSKERKL----LEERISD-- 3 ( 403) -LNSHETTITQQSVSDSHLAELQEKIQQTEATN-----------------------KI-- 4 ( 350) -MKAQEEMIS--ELR------QQKFYLETQAGKLEAQ-----NRK------LEEQLEK-- // 0 ( 333) -----L-EEDLREKEREIATE---KKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLS 1 ( 375) ATNKIL-QEKLNEMSYELKCA---QESSQKQDGTIQNLKETLKSRERETEELYQVIEGQN 2 ( 1023) -----L-TTNLAEEEEKAKNL---TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 3 ( 437) -----L-QEKLNEMSYELKCA---QESSQKQDGTIQNLKETLKSRERETEELYQVIEGQN 4 ( 388) -----ISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQ // 0 ( 384) AAFAKAREALQKAQTQEFQGSEDYETALSGKEA-LSAALRSQ--NLTKS-TENHRLRRSI 1 ( 431) DTMAKLREMLHQSQLGQLHSSEGTSPAQQQVAL-LD--LQSA--LFCSQ-LEIQKLQRVV 2 ( 1074) GDASDFHEQIADLQAQ----IAELKMQLAKKEEELQAALARL--DDEIA-QKNNALKK-I 3 ( 488) DTMAKLREMLHQSQLGQLHSSEG--TSPAQQQV-ALLDLQSA--LFCSQ-LEIQKLQRVV 4 ( 443) AARAALESQLRQAKTELEETTAEAEEEIQALTA-HRDEIQRKFDALRNSCTVITDLEEQL // 0 ( 440) KKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRY 1 ( 485) RQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQL---- 2 ( 1126) RELEGHISDLQE-------DLDSERAARNKAEKQKRDLGEELEALKTE-------LEDTL 3 ( 542) RQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQL---- 4 ( 502) NQLTEDNAELNNQNFYLSKQLDEA----SGANDEIVQLRSEVDHLRREITEREMQLTSQK // 0 ( 500) KSLLSESNKKLHNQEQVI---KHLTESTNQKDVLLQKFNE----KDL--E----VI---- 1 ( 541) RAWEAEKYNEIRTQEQNI---QHLNHSLSHKEQLLQEFRELLQYRDNSDK----TL---- 2 ( 1172) DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ----KHA--Q----AVEELT 3 ( 598) RAWEAEKYNEIRTQEQNI---QHLNHSLSHKEQLLQEFRE----LLQ--Y----RD---- 4 ( 558) QTMEALKTTCTMLEEQVM---D--LEALN--DELLEK--E----RQW--EAWRSVL---- // 0 ( 543) -QQNCYLMAA-----EDLELRSEGLITEKCSS--QQPPGSKTIFSKEKKQSSDYEELIQV 1 ( 590) -EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDV 2 ( 1222) EQLEQFKRAK-----ANLDKNKQTL--EKENA--DLA-GELRVLGQAKQEVEHKKKKLEA 3 ( 641) -NSDKTLEAN-----EMLLEKLRQRIHDKAVA--LERAIDEKFSALEEKEKELRQLRLAV 4 ( 599) -GDEKSQFEC-----RVRELQ-RMLDTEK-QS--RARADQRITESRQVVELAVKEHKAEI // 0 ( 595) LKKE----QDIYTHL-VKSL---QE-SDSINNLQ---AELNKIFALRKQLE-------QD 1 ( 649) LSSNEATMQSMESLLRAKGLEVEQL-STTCQNLQWLKEEMETKFS-RWQKE-------QE 2 ( 1272) QVQEL---QSKCSDG-ERAR---AELNDKVHKLQ---NEVESVTGMLNEAEGKAIKLAKD 3 ( 693) RERD----HDL-ERL-RDVL---SS-NEA--TMQ---SMESLLRAKGLEVE-------QL 4 ( 649) LALQ----QALKEQK-LKAE---SL-SDKLNDLE---KKHAMLEMNARSLQ-------QK // 0 ( 636) VLSY----Q-------------NLRKTL------------EEQI-------SEIRRREEE 1 ( 700) SIIQ----QLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELC-------QRLQRKERM 2 ( 1322) VASLSSQLQ-------------DTQELL------------QEETRQKLNVSTKLRQLEEE 3 ( 731) STTC----Q-------------NLQWLK------------EEME-------TKFSRWQKE 4 ( 690) LETE----R-------------ELKQRL------------LEEQ-------AKLQQQMDL // 0 ( 660) SFSLYSDQTSY-LSICLEENNRFQVEHFSQEELKKKVSDLI--QLVKELYTDNQHLKKTI 1 ( 749) LQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLV--QALMERNSELQALRQYL 2 ( 1357) RNSLQDQLDEE-MEAKQNLERHISTLNIQLSDSKKKLQDFA--STVEALEEGKKRFQKEI 3 ( 755) QESIIQQ-----LQTSLHDRNK-EVEDLSATLLCKLGPGQS--EIAEELCQRLQRKERML 4 ( 714) QKNHIFRLTQG-LQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTK... // 0 ( 717) FDLSCMGFQGNGFPDRLASTEQTEL-LASKEDEDTIKI-GEDDEINFLSDQHLQQS--NE 1 ( 807) GGRDSLMSQAP-ISNQQAEVTPTGR-LGKQTDQGSMQIPSRDDSTSLTAKEDVSIP--RS 2 ( 1414) ENLTQQYEEKAAAYDKL---EKTKN-RLQQELDDLV-V-DLDNQRQLVSNLEKKQRKFDQ 3 ( 807) QDL---------LSDRNKQVLEHEMEIQGLLQSVSTRE-QESQAAAEKLVQALMER--NS 4 ( -) ............................................................ // 0 ( 773) IMKDLSK--GGCKNGYLR---HTESKISDCDGAHAP-GCL-EEGAFINLLAPLFNE---K 1 ( 863) TLGDLDT--VAGLEKELS---NAKEELELMAKKERE-SQM-ELSALQSMMAVQEEELQVQ 2 ( 1468) LLAEEKN--ISSKYADERDRAEAEAREKETKALSLA-RAL-EEALEAKEELERTNKML-K 3 ( 855) ELQALRQYLGG-RDSLM-----SQAPISNQQAEVTPTGRLGKQTDQGSMQIPSRDD---S 4 ( -) ............................................................ // 0 ( 823) ATL--L------LESRPDLLKVVR------------ELL--LGQLFLTEQEVSG--EHLD 1 ( 916) AAD--MESLTRNIQIKEDLIKDLQMQLVDPEDIPAMERL--TQEVLLLREKVAS--VESQ 2 ( 1523) AEMEDL------VSSKDDVGKNVH------------EL------------EKSK--RALE 3 ( 906) TSL----------TAKEDV-SIPR------------STLGDLDTVAGLEKELSNAKEELE 4 ( -) ............................................................ // 0 ( 859) GKTEKTPKQKGELVHFVQ--TNSFSKPHDELKLSCE--AQLVKAGEVPKVGLKDASVQTV 1 ( 970) GQ-EISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAHPESSERDRTLQ-V 2 ( 1551) TQMEEMKTQLEELEDELQ--ATEDAK----LRLEVN--MQALK-GQFER-DLQARDEQNE 3 ( 943) LMAKKERESQMELSALQS--MMAVQEEELQVQAADM--ESLTRNIQIKEDLIKDLQMQLV 4 ( -) ............................................................ // 0 ( 915) ATEG--DLLRFKHEATREAWEEKPINTALSAEHRPENLHGVPGWQAALLSLPGITN---- 1 ( 1028) ELEGA-QVLRSRLEEV--------LGRSLERLNRLETLAAIGGAAAGDDTEDTSTEFTDS 2 ( 1601) EKRR--QLQRQLHEYETELEDERK-QRALAAAAK-KKLEG-DLKDLELQADSAIKG---- 3 ( 999) DPEDIPAMERLTQEVL--LLREK----VASVESQGQEISG-NRRQQLLLMLEGLVD---- 4 ( -) ............................................................ // 0 ( 969) --REAKKSRLPILIKPS--RSL-GNMYRL--------PATQEVVTQLQSQILELQGELKE 1 ( 1079) IEEEAAHHSHQQLVKVALEKSL-ATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQ 2 ( 1652) --REEA-------IKQL--R-------------------------KLQAQMKDFQRELED 3 ( 1048) -----ERSRLNEALQAE--RQLYSSLVKF--------HAHPESSERDRTLQVELEGA--- 4 ( -) ............................................................ // 0 ( 1016) FKTCNKQLHQKLI-LAEAVMEGRPTPDKTLLNAQPPVGAAYQ-----DSPGEQKGIKTTS 1 ( 1138) HLEEKRKAEEELKELKAQIEEAGFSSVSHIRNTM--LSLCLE-----NAELKEQMGEAMS 2 ( 1676) ARASRDEI---FA-TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 3 ( 1090) -----QVLRSRL----EEVL-GRSLERLNRLETLAAIGGAAA-----GDDTEDTSTEFTD 4 ( -) ............................................................ // 0 ( 1070) SVWRDKEMDSDQQRSYEIDSEICP----PDDLASLPS-----------CKENPED-VLSP 1 ( 1191) DGW---EIEEDKEKG-ELDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQD-LQEK 2 ( 1732) SL-SGRNALQDEKRRLE--ARIAQL---EEELEEEQG-----------NMEAMSDRVRKA 3 ( 1135) SIEEEAAHHSHQQ............................................... 4 ( -) ............................................................ // 0 ( 1114) T--SVATYLSSKSQPSAKVSVMGTDQSESINTSNETEYLKQKIHDL--------ETELEG 1 ( 1246) LLLSEATVFA-QANELEKYRVMLT--GESL-VKQDSKQIQVDLQDLGYETCGRSENEAER 2 ( 1775) T--QQAEQLSN--ELATERSTAQKNESARQQLERQNKELRSKLHEM--------EGAVKS 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1164) -YQNFIFQLQ-KHSQCSEAIITV-LCGTEG------AQDGLSKPKNGSDGEEMTFSSLHQ 1 ( 1302) -EETTSPECE-EHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQEEFRVYGK 2 ( 1823) KFKSTIAALEAKIAQLEEQV-------EQE------AREKQAATKSLKQKDKKLKEILLQ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1215) VRYVKHV-KILGPLAPEMIDS-RVLENLKQQL---------------------------- 1 ( 1360) SENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLERPRKLRAVGTLEGS 2 ( 1870) VEDERKM-AEQYKEQAEKGNA-RV-KQLKRQL---------------------------- 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1245) ------EEQE----------YK--LQKEQNL----N--MQLFSEIH----------NLQN 1 ( 1420) SPHSVPDEDEGWLSDGTGAFYSPGLQAKKDL----ESLIQRVSQLEAQLPKNGLEEKLAE 2 ( 1899) ------EEAEEESQRINANRRK--LQRELDEATESN--EAMGREVN----------ALKS 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1271) KFRDLS-PPRYDSLVQSQARELSLQRQQIKDGHGICVISRQHMNTMIKAFEELLQASDVD 1 ( 1476) ELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLLRSNDID 2 ( 1939) KLR......................................................... 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1330) YCVAEGFQEQLNQCAELLEKLE-KLFL-NGKS----VGVE---MNTQNELMERIEEDNLT 1 ( 1536) YYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLSRELQEKEKVIEVL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1381) YQHLLPESPEPSASHALSD-----------------------------YE---------- 1 ( 1596) QAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHYEEKKASPSHSD 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1402) ---------------------------------------------------------TSE 1 ( 1656) SIHHSSHSAVLSSKPSSTSASQGAKAESNSNPISLPTPQNTPKEANQAHSGASTVPPAST 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1405) KSFFSRDQKQDN-------------------------------------ETEKTSV---- 1 ( 1716) ATLLSNDLEADSSYYLNSAQPHSPPRGTIELGRILEPGYLGSSGKWDVMRPQKGSVSGDL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1424) -------MVNS--FSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQG--S 1 ( 1776) SSGSSVYQLNSKPTGADLLEEHLGEIRNLRQRLEESICINDRLREQLEHRLTSTARGRGS 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1473) TSIFAS-GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEH 1 ( 1836) TSNFYSQGLESIPQLCNENRVLREDNRRLQAQLSHVSREHSQETESLREALLSSRSHLQE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1532) LQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQEL-SRVQEELKLRQQLLSQNDK 1 ( 1896) LEKELEHQKVERQQLLEDLREKQQEVLHF-REERLSLQENDSRLQHKLVLLQQQCEEKQQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1591) LLQSLRVELKAYE-------------KLDEEH---------------RRLRDGDKYPMES 1 ( 1955) LFESLQSELQIYEALYGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRALRGQLEQSIQG 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1623) DNSFDLFDSSQ--------AVTPKSVSE--------------------TPPLS--GNDTD 1 ( 2015) NNCLRLQLQQQLESGAGKASLSPSSINQNFPASTDPGNKQLLLQDSAVSPPVRDVGMNSP 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1653) SLSCDSGSSATS---TPCVSR-----------LVTGHHL--------WASKNGRHVLGLI 1 ( 2075) ALVFPSSASSTPGSETPIINRANGLGLDTSPVMKTPPKLEGDATDGSFANKHGRHVIGHI 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1691) EDYEALLKQISQGQRLLAEMDIQTQEAPSSTSQE------LGTKGPHPAPLSKFVSSVST 1 ( 2135) DDYSALRQQIAEGKLLVKKIVSLVRSACSFPGLEAQGTEVLGSKGIH-----ELRSSTSA 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1745) AKLTLEEAYRRLKLLWRVSLPEDGQCPLHCEQIGE-MKAEVTKLHKKLFEQEKKLQNTMK 1 ( 2190) LHHALEESASLLTMFWRAALP-STHIPVLPGKVGESTERELLELRTKVSKQERLLQSTTE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1804) LLQLSKRQ----EKVIFDQLVVTHKILRKARGNLELRPGGAHPGTCSPSRPGS 1 ( 2249) HLKNANQQKESMEQFIVSQLTRTHDVLKKARTNLEVKSLRALP--CTPA.... 2 ( -) ..................................................... 3 ( -) ..................................................... 4 ( -) ..................................................... //