# 0 KIAA1361, 1005 aa # 1 KIAA0881 (1064 aa) # 2 KIAA0204 (1164 aa) # 3 KIAA0551 (1385 aa) # 4 KIAA0687 (1175 aa) # 5 KIAA1142 (467 aa) // exp sw-scr id% from to 1 2.5e-57 4769 70.4 16 1064 2 3.3e-13 764 25.2 23 932 3 1.8e-12 861 30.9 26 564 4 6.4e-12 749 30.3 2 519 5 6.7e-11 588 36.7 192 465 // 0 ( 1) LLSRMPSTNRAGSLKDPEIAELFFKE-DPEKLFTDLREIGHGSFGAVYFARDVRTNEVVA 1 ( 16) ....MPAGGRAGSLKDPDVAELFFKD-DPEKLFSDLREIGHGSFGAVYFARDVRNSEVVA 2 ( 23) .........KLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAA 3 ( 26) ....MASDSPARSLDEIDLSAL---R-DPAGIFELVELVGNGTYGQVYKGRHVKTGQLAA 4 ( 2) ..............................................VYKGRHVKTGQLAA 5 ( 192) ...........................DPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVA // 0 ( 60) IKKMSYSGKQSTEKWQDIIK-EVKFLQRIKHPNSIE-YKGCYLREHTA------WLVMEY 1 ( 71) IKKMSYSGKQSNEKWQDIIK-EVRFLQKLRHPNTIQ-YRGCYLREHTA------WLVMEY 2 ( 74) AKVID---TKSEEELEDYMV-EIDILASCDHPNIVK-LLDAFYYENNL------WILIEF 3 ( 78) IKVMDVTGDEEEE----IKQ-EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEF 4 ( 16) IKVMDV-----TEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEF 5 ( 225) VKKMDLRKQQRREL---LFN-EVVIMRDYQHENVVE-MYNSYLVGDEL------WVVMEF // 0 ( 112) C-LGSASD--LLEVHK-KPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPG 1 ( 123) C-LGSASD--LLEVHK-KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPG 2 ( 123) C-AGGAVDAVMLEL-E-RPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDG 3 ( 133) CGAGSVTD--LIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENA 4 ( 71) CGAGSITD--LVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENA 5 ( 274) L-EGGALT--DIVTHT-R-MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDG // 0 ( 168) QVKLADFG-SASMASPA----NSFVGTPYWMAPEVIL--AMDEGQ---YDGKVDVWSLGI 1 ( 179) LVKLGDFG-SASIMAPA----NSFVGTPYWMAPEVIL--AMDEGQ---YDGKVDVWSLGI 2 ( 180) DIKLADFG-VSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRP---YDYKADVWSLGI 3 ( 191) EVKLVDFGVSAQLDRTVGRR-NTFIGTPYWMAPEVI---ACDENPDATYDFKSDLWSLGI 4 ( 129) EVKLVDFGVSAQLDRTVGRR-NTFIGTPYWMAPEVI---ACDENPDATYDYRSDLWSCGI 5 ( 329) RVKLSDFG-FCAQVSKEVPRRKSLVGTPYWMAPELIS--RLP------YGPEVDIWSLGI // 0 ( 218) TCIELAERKPPLFNMNAMSALYHIAQNESPTL-QS-NEWSDYFRNFVDSCLQKIPQDRPT 1 ( 229) TCIELAERKPPLFNMNAMSALYHIAQNESPVL-QS-GHWSEYFRNFVDSCLQKIPQDRPT 2 ( 236) TLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQP-SRWSSNFKDFLKKCLEKNVDARWT 3 ( 247) TAIEMAEGAPPLCDMHPMRALFLIPRNPAPRL-KS-KKWSKKFQSFIESCLVKNHSQRPA 4 ( 185) TAIEMAEGAPPLCDMHPMRALFLIPRNPPPRL-KS-KKWSKKFFSFIEGCLVKNYMQRPS 5 ( 380) MVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL-KNLHKVSPSLKGFLDRLLVRDPAQRAT // 0 ( 276) SEELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEE 1 ( 287) SEVLLKHRFVLRERPPTVIMDLIQRTKDAVRELDNLQYRKMKKILFQEAPNGPGAEAPEE 2 ( 295) TSQLLQHPFVT--------VD----SNKPIREL----IAEAKAEVTEEVEDG---KEEDE 3 ( 305) TEQLMKHPFI-RDQPNERQVRI--QLKDHI---DRTKKKRGEKDETEYEYSG----SEEE 4 ( 243) TEQLLKHPFI-RDQPNERQVRI--QLKD---HIDRTRKKRGEKDETEYEYSG----SEEE 5 ( 439) AAELLKHPFLAKAGPPASIVPLMRQNR................................. // 0 ( 336) EEEQDHGVGRTGTVNSVGSNQSIPSMSISASSQSSSVNSLPDVSDDKSELD--------- 1 ( 347) EEEAEPYMHRAGTLTSLESSHSVPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEE 2 ( 336) EEETENSLPIPAS-KRASSDLSIASSEEDKLSQNACI--LESVSE-KTERS--------- 3 ( 355) EEENDSG-------------------------EPSSILNLPGESTLRR--D--------- 4 ( 293) EEE-------------VPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERS--------- 5 ( -) ............................................................ // 0 ( 387) ----------MMEGDHTVMSNSSVIHLKPE-EEN-YREEGDPRTRASDPQSPPQV----- 1 ( 407) EGPEAREMAMMQEGEHTVTSHSSIIHRLPG-SDNLYDDPYQPEITPS-PLQPPAAPAPTS 2 ( 383) ----------NSE-DKL---NSKILNEKPTTDEP-EKAVEDINEHITDAQLEAMT----- 3 ( 379) ----------FLRLQLANKERSEALRRQQL-EQQ-QRENEEHK-RQLLAERQKRI----- 4 ( 331) ----------EALRRQQLLQEQ---QLREQ-EEY-KRQLLAERQKRIEQQKEQRR----- 5 ( -) ............................................................ // 0 ( 430) ----SRHKSHYRNREHFATIRTASLVTRQMQEHEQDSELREQMSGYKRMRRQHQKQLMTL 1 ( 465) TTSSARRRAYCRNRDHFATIRTASLVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLAL 2 ( 423) ----ELH-------DRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITL 3 ( 421) ----EEQKEQRR---------------RLEEQQRREKELRKQQE--REQRRHYEEQMRRE 4 ( 371) ----RLEEQQRRERE-----------ARRQQEREQRRREQEEKRRLEELERRRKEE---- 5 ( -) ............................................................ // 0 ( 486) ENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMSNEEKK--FQQH 1 ( 525) ESRLRGEREEHSARLQRELEAQRAGFGAEAEKLARRHQAIGEKEARAAQAEERK--FQQH 2 ( 472) ETNI-----EHNLK-------------SEEEKDQEKQQMF---ENKLIKSEEIKDTILQT 3 ( 460) EERRRAEHEQEYIR--RQLEEEQRQLEILQQQLL--HEQALLLEYKRKQLEEQR--QAER 4 ( 412) EERRRAE--EEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRP--HPQH 5 ( -) ............................................................ // 0 ( 544) IQ--A----QQKKELNSFLESQKR---EYKLRKEQLKEELNE-NQSTPKKEKQEWLSKQK 1 ( 583) IL--G----QQKKELAALLEAQKR---TYKLRKEQLKEELQE-NPSTPKREKAEWLLRQK 2 ( 511) VDLVS----QETGEKEANIQAVDS---EVGLTKEDTQEKLGE-DDKTQK----DVISNTS 3 ( 514) LQ--R----QLKQERDYLVSLQHQ---RQEQRPVEKKPLYHY-KEGMSPSEKPAWAKEVE 4 ( 468) SQ--QPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQ...... 5 ( -) ............................................................ // 0 ( 594) ENIQHFQAEEEANLLRRQ----------RQYLELECRRFKRRML---LG-------RHNL 1 ( 633) EQLQQCQAEEEAGLLRRQ----------RQYFELQCRQYKRKML---LA-------RHSL 2 ( 559) DVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIV 3 ( 564) E........................................................... 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 634) EQDLVREELNKRQTQKDLEHAMLLRQHE------------SMQELEFRHLNTIQKMRCEL 1 ( 673) DQDLLREDLNKKQTQKDLECALLLRQHE------------ATRELELRQLQAVQRTRAEL 2 ( 619) EMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALG 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 682) IRLQHQTELTNQLEYNKRR-ERELRRKHVMEVRQQPK----------SLKSKELQIKKQF 1 ( 721) TRLQHQTELGNQLEYNKRR-EQELRQKHAAQVRQQPK----------SLKSKELQIKKQF 2 ( 679) SEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKEEI 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 731) QDTCKIQTRQYKALRN-----------HLLETTPKSEHKAV---LKRLKE-------EQT 1 ( 770) QETCKIQTRQYKALRA-----------HLLETTPKAQHKSL---LKRLKE-------EQT 2 ( 739) GSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQETR 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 770) RKLAILAEQYDHSINEM---LSTQALRLD-EAQEAECQVLKMQLQQELELLNAYQSKIKM 1 ( 809) RKLAILAEQYDQSISEM---LSSQALRLD-ETQEAEFQALRQQLQQELELLNAYQSKIKI 2 ( 799) RQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 826) Q--AEAQHDRE--LRELEQRVSLRRALLEQKIE-------EEMLALQNERTERIRSLLER 1 ( 865) R--TESQHERE--LRELEQRVALRRALLEQRVE-------EELLALQTGRSERIRSLLER 2 ( 859) QLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKR 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 875) ----QAREIEAFDSESMRLGFSNMVLSNLSPEAFSHSYPG---ASGWSHNPTGGPGPHWG 1 ( 914) ----QAREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWS 2 ( 919) IKGEQEKELSKFQN.............................................. 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 928) H---PMGGPPQAWGHP---MQGGPQPWGHPSGPMQ-GVPRGSSMGV-RNSPQALRRTASG 1 ( 970) HGPPPPGMPPPAWRQPSLLAPPGPPNWLGP--PTQSGTPRGGALLLLRNSPQPLRRAASG 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 980) GRTEQG-----------MSRSTSVTSQISNGSHMSYT 1 ( 1028) GSGSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS 2 ( -) ..................................... 3 ( -) ..................................... 4 ( -) ..................................... 5 ( -) ..................................... //