# 0 KIAA1488, 852 aa # 1 KIAA0890 (1210 aa) # 2 KIAA0577 (1043 aa) # 3 KIAA0224 (1256 aa) # 4 KIAA0134 (587 aa) # 5 KIAA1517 (998 aa) // exp sw-scr id% from to 1 8.8e-55 1679 36.3 429 1171 2 5.2e-34 1071 32.4 394 1011 3 3.4e-32 1031 29.9 512 1165 4 1.3e-30 801 31.7 153 544 5 1.8e-22 841 28.1 64 822 // 0 ( 1) IRNRSYIDRDSEYLLQENEPD------GTLD----QKLLEDLQKKKN-DLRYIEMQHF-- 1 ( 429) .............................LS----QSLLE-LWRRRG-PV-----WQE-- 2 ( 394) ......................................................IQAV-- 3 ( 512) ...............KEEEPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFAKKKSILE 4 ( 153) ........................................DFGQKQA-FGRLAKLQRE-- 5 ( 64) ..................................................RSPEMQEE-- // 0 ( 48) -REKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFIL-DN-YIERGKGSACRIV 1 ( 447) -APQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLL-ER-YVTEGRGARCNVI 2 ( 398) -RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLF-EEGYTNKGM----KIA 3 ( 557) QRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDG-YTDYGM-----IG 4 ( 170) -RAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL---------AAGFSHVA 5 ( 72) -RLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLY------EAGFSSEDSII // 0 ( 105) -CTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGS-IL-YCTTGIILQ 1 ( 504) -ITQPRRISAVSVAQRVSHELGPSLRR--NVGFQVRLESKPPSRGGA-LL-FCTVGILLR 2 ( 452) -CTQPRRVAAMSVAARVA--REMGVKLGNEVGYSIRFEDCTSER--T-VLRYMTDGMLLR 3 ( 611) -CTQPRRVAAMSVAKRVSEEMGGNLG--EEVGYAIRFED-CTSENTL-IK-YMTDGILLR 4 ( 220) -CTQPRRIACISLAKRVGFESLSQYGS--QVGYQIRFES--TRSAATKIV-FLTVGLLLR 5 ( 125) GVTEPRRVAAVAMSQRVAKEMNLS---QRVVSYQIRYEGNVT-EETR-IK-FMTDGVLLK // 0 ( 162) WLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD----LKVILMSATLNAEK 1 ( 559) KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPA----LRLVLMSATGDNER 2 ( 506) EFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPE----LKVLVASATMDTAR 3 ( 665) ESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSD----LKLIVTSATMDAEK 4 ( 274) QIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPD----LKVILMSATINISL 5 ( 179) EIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVED // 0 ( 218) FSE---YFGNCP-MIHIPGFTFPVVEYL-----LEDV-------IEKI-RYVPE------ 1 ( 615) FSR---YFGGCP-VIKVPGFMYPVKEHY-----LEDI-------LAKL-G---------- 2 ( 562) FST---FFDDAP-VFRIPGRRFPV-----------DI-------F--Y-TKAPE------ 3 ( 721) FAA---FFGNVP-IFHIPGRTFPV-----------DI-------L--F-SKTPQ------ 4 ( 330) FSS---YFSNAP-VVQVPGRLFPIT----------------------------------- 5 ( 239) FTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIHRMLPAGGILVF // 0 ( 255) ---QKEHRS---QFKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEM 1 ( 648) --------------KHQYLHRH-RHHESEDECAL-------------------------- 2 ( 591) ---A------------------------------------DYLE-------ACVVSVLQI 3 ( 750) ---E------------------------------------DYV----------------- 4 ( -) ------------------------------------------------------------ 5 ( 299) LTGQAEVHALCRRLRKAFPPSRARPQEKDDDQKDSVEEMRKF-KKSRARAKKARAEVLPQ // 0 ( 309) MEDDKVDLNLIVALI---RYIVLEEEDGAI-----LVFLPGWDNISTLHDLLMSQV--MF 1 ( 667) ------DLDLVTDLV---LHIDARGEPGGI-----LCFLPGWQEIKGVQQRLQEAL--GM 2 ( 605) H---------------------VTQPPGDI-----LVFLTGQEEIEAACEMLQDRC--RR 3 ( 754) --EAAVKQSLQVHL---------SGAPGDI-----LIFMPGQEDIEVTSDQIVEHLEELE 4 ( -) ------------------------------------------------------------ 5 ( 358) INLDHYSV-LPAGEGDEDREAEVDEEEGALDSDLDLDLGDGGQDGGEQPD---------- // 0 ( 359) KSDK---FLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGK 1 ( 711) HESK---YLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGL 2 ( 637) LGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGF 3 ( 798) NAPA---LAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGY 4 ( 351) ------------------------VFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGK 5 ( 407) ASLP---LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGK // 0 ( 416) IKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLY--NGL-RASLLDDYQL 1 ( 768) HKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLF--PRS-RLEKMVPFQV 2 ( 697) CKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLY--TAWAYQHELEETTV 3 ( 855) CKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQSAY-KNELLTT-TV 4 ( 387) VKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLY--AES-DYDAFAPYPV 5 ( 464) VKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLY--SSA-VFGDFEQFPP // 0 ( 473) PEILRTPLEELCLQIKI-LRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDK----- 1 ( 825) PEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQ----- 2 ( 755) PEIQRTSLGNVVLLLKS-LGIHDLMHF--DFLDPPPYETLLLALEQLYALGALNH----- 3 ( 913) PEIQRTNLANVVLLLKS-LGVQDLLQF--HFMDPPPEDNMLNSMYQLWILGALDN----- 4 ( 444) PEIRRVALDSLVLQMKS-MSVGDPRTF--PFIEPPPPASLETAILYLRDQGALDS----- 5 ( 521) PEITRRPVEDLILQMKA-LNVEKVINF--PFPTPPSVEALLAAEELLIALGALQPPQKAE // 0 ( 527) -----QEE-----LTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP-F 1 ( 880) -----REY-----LTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDP-F 2 ( 807) -----LGE-----LTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIF 3 ( 965) -----TGG-----LTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAI-F 4 ( 496) -----SEA-----LTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSVQSP-F 5 ( 578) RVKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVREL-F // 0 ( 576) VIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRY---------EKD-YC 1 ( 928) SSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRS---------SRENYL 2 ( 857) YRPKDKVVHADNARVNFFLPG-GDHLVLLNVYTQWAES---G--Y---------SSQ-WC 3 ( 1014) YRPKGREEESDQIREKFAVP-ESDHLTYLNVYLQWKNNN-----Y---------STI-WC 4 ( -) ............................................................ 5 ( 637) E-ELDRPAASDEELTRL-KSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYA-SC // 0 ( 626) WEYFLSSNTLQM-----LHNMKGQFAEHLLGAGFVSSRNPKD-----PESNINSDNE-KI 1 ( 979) EENLLYAPSLRF-----IHGLIKQFSENIYEAFLVG--KPSDCTLASAQCNEYSEEE-EL 2 ( 901) YENFVQFRSMRR-----ARDVREQL-EGLLERVEVGL------------SSCQGDYI-RV 3 ( 1058) NDHFIHAKAMRK-----VREVRAQLKDIM-----VQQRM--------SLASCGTDWD--I 4 ( -) ............................................................ 5 ( 694) TPQFCEANGLRYKAMMEIRRLRGQLTTSV-NAVCPEAELFVD-----PKMQPPTESQVTY // 0 ( 675) IKAVICAGLYPKVAK-IRLN----LGKKRKMVKVYTKT---DGLVAVHPKSVNVEQTDFH 1 ( 1031) VKGVLMAGLYPNLIQ-VRQGKVTRQGKFKPNSVTYRTK---SGNILLHKSTINREATRLR 2 ( 942) RKA-ITAGYFYHTA---RLT----RSGYRTV-----KQ---QQTVFIHPNSSLFEQ---Q 3 ( 1098) VRKCICAAYFHQAAK-LK-G----IGEY-----VNIRT---GMPCHLHPTS-SLFGMGYT 4 ( -) ............................................................ 5 ( 748) LRQIVTAGLGDHLARRVQSE----EMLEDKWRNAY-KTPLLDDPVFIHPSSVLFKELP-- // 0 ( 727) YNWLIYHLKMRTS-SIYLYDCTEVSPYC-LLFFGGDISIQKDNDQETIAVDE--WIVFQS 1 ( 1087) SRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEG 2 ( 983) PRWLLYHELVLTT-KEFMRQVLEIESSW-LL............................. 3 ( 1143) PDYIVYHELVMTT-KEYMQCVTAV.................................... 4 ( -) ............................................................ 5 ( 801) -EFVVYQEIVETT-KMYMKGVSSV.................................... // 0 ( 783) PARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNF 1 ( 1147) DSRTVRLLKELRRALGRMVERSLRS................................... 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 843) PPRFQDGYYS 1 ( -) .......... 2 ( -) .......... 3 ( -) .......... 4 ( -) .......... 5 ( -) .......... //