# 0 KIAA1590, 1393 aa # 1 KIAA0042 (1652 aa) # 2 KIAA0639 (1835 aa) # 3 KIAA0591 (1849 aa) # 4 KIAA1448 (1179 aa) # 5 KIAA0706 (1123 aa) // exp sw-scr id% from to 1 7.2e-35 1650 40.9 361 1079 2 7.5e-31 1643 39.5 13 816 3 9.5e-30 1731 39.5 37 923 4 1.6e-27 1791 35.7 30 1152 5 1.4e-26 1630 42.5 22 741 // 0 ( 1) AMASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYD 1 ( 361) ..SQVTVAVRVRPFTKREKIEKASQVVFMSGKEITVEH---PD-------TKQVYNFIYD 2 ( 13) ..SKVKVAVRIRPMNRRETDLHTKCVVDVDANKV-ILNPVNTNLSKGDA-RGQPKVFAYD 3 ( 37) ..ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP--------KEAPKSFSFD 4 ( 30) ..ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP--------KEAPKSFSFD 5 ( 22) AGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPK--------QSKDAPKSFTFD // 0 ( 61) FSFYS-ADT-KSPD-YVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNS 1 ( 409) VSFWS-FDE-CHPH-YASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFS 2 ( 69) HCFWS-MDE-SVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTA 3 ( 87) YSYWS-HTSPEDPC-FASQNRVYNDIGKEMLLHAFGGYNVCIFAYGQTGAGKSYTMMGKQ 4 ( 80) YSYWS-HTSPEDPC-FASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQ 5 ( 74) YSYWSHTST-EDPQ-FASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQ // 0 ( 118) --GDS--GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKS---SKT 1 ( 466) --EEP--GIIPRFCEDLFSQVARK-QTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRK 2 ( 127) --DQP--GLIPRLCSGLFERTQKEEN-EEQSFKVEVSYMEIYNEKVRDLLDPKG---SRQ 3 ( 145) --EESQAGIIPQLCEELFEKINDNCN-EEMSYSVEVSYMEIYCERVRDLLNPKN---KG- 4 ( 138) --EESQAGIIPQLCEELFEKINDNCN-EEMSYSVEVSYMEIYCERVRDLLNPKN---KG- 5 ( 132) EPGQQ--GIVPQLCEDLFSRVSENQS-AQLSYSVEVSYMEIYCERVRDLLNPKS---RGS // 0 ( 171) FNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTI 1 ( 521) QPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTL 2 ( 179) -TLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKI 3 ( 198) -NLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTI 4 ( 191) -NLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTI 5 ( 186) --LRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTI // 0 ( 231) KFTQAKFD----SE--MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLG 1 ( 581) VMTQTKTEFVEGEE--HDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLG 2 ( 238) TLTHTLYDVK--SG--TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLG 3 ( 257) VFTQKKHD----NETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLG 4 ( 250) VFTQKKHD----NETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLG 5 ( 244) VFTQRCHDQL--TG--LDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLG // 0 ( 285) NVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYG 1 ( 639) KVISALSEQ--------ANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIE 2 ( 294) LVISALAD--QSA----GKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYD 3 ( 313) KVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYD 4 ( 306) KVISALAEVSKK------KKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYD 5 ( 300) KVISALADMQSK------KRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYE // 0 ( 345) ETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLL-AQG------------ 1 ( 691) ETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKA---AQR------------ 2 ( 348) ETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQL-TKA------------ 3 ( 373) ETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDIDPLID 4 ( 360) ETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDT----- 5 ( 354) ETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQG------------ // 0 ( 392) -------------------------NQI----------AL------LD------------ 1 ( 736) -------------------------NSR----------NIDPERYRLC------------ 2 ( 395) -------------------------EA-------------------MK------------ 3 ( 433) DYSGSGSKYLKDFQNNKHRYLLASENQRPGHFSTASMGSL------TS------------ 4 ( 415) -------------------------SMG----------SL------TS------------ 5 ( 402) -------------------------LSA----------SA------LEGLKTEEGSVRGA // 0 ( 399) --------------SPTALSME-------------------------EKLQQNEARVQEL 1 ( 749) --------------RQEITSLR-------------------------MKLHQQERDMAEM 2 ( 399) --------------SPE---LK-------------------------DRLEESEKLIQEM 3 ( 475) --------------SPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAEL 4 ( 422) --------------SPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAEL 5 ( 421) LPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAM------ERLQETEKIIAEL // 0 ( 420) TKEWTNKWNETQNI-------LKEQTLALRKEG--I-----GVVLDSELPHLIGIDDDLL 1 ( 770) QRVWKEKFEQAEKR-------KLQETKELQKAG--I-----MFQMDNHLPNLVNLNEDPQ 2 ( 417) TVTWEEKLRKTEEI-------AQERQKQLESLG--ISLQSSGIKVGDDKCFLVNLNADPA 3 ( 521) NETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTL-----GVFSPKKTPHLVNLNEDPL 4 ( 468) NETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTL-----GVFSPKKTPHLVNLNEDPL 5 ( 475) NETWEEKLRKTEALRMEREALLAEMGVAVREDGGTV-----GVFSPKKTPHLVNLNEDPL // 0 ( 466) STGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFE----NI---G-G--T-VT 1 ( 816) LSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK----NF---G-G--T-VS 2 ( 468) LNELLVYYLKE-HTLIG---SANSQDIQLCGMGILPEHCIID----IT---SEG--Q-VM 3 ( 576) MSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNS---G-E--VIVT 4 ( 523) MSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNS---G-E--VIVT 5 ( 530) MSECLLYHIKDGVTRVGQVD----MDIKLTGQFIREQHCLFR----SIPQPD-GEVV-VT // 0 ( 515) LIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLR---EKRKSGLLS 1 ( 865) IIPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQK-----GKRPSGRDT 2 ( 514) LTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDQDPSMKN 3 ( 630) LEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAER---EKTPSAETP 4 ( 577) LEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAER---EKTPSAETP 5 ( 580) LEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHP-EQARLE---RERGVPPPP // 0 ( 572) SFSLSMTDLS-KSRENLSAVMLYNPGLEFE----------RQQREELEK-------LESK 1 ( 920) PISEGPKDFE-FAKNEL--LM--------------------AQRSQLEA--------EIK 2 ( 574) ENSSEQLDVDGDSSSEVSSEVNFN----YE----------YAQMEVTMKALGSNDPMQSI 3 ( 687) SEPVDWT--F-AQRE-----LLEKQGID--------------MKQEMEK----------- 4 ( 634) SEPVDWT--F-AQRE-----LLEKQGID--------------MKQEMEK-------R--- 5 ( 636) GPPSEPVDWN-FAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADL-------LLEQ // 0 ( 614) RKLIEEMEEKQKSDKAELERMQQEVETQRK--ETE--IVQLQIRK--QE-ESLKRRSFH- 1 ( 949) EAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESK--IKALEAEL--RE-ESQRKKMQE- 2 ( 620) LNSLEQQHEEEKRSALERQRLMYEHELEQL--RR-----RLSPEK--QNCRSMDRFSFHS 3 ( 714) --RLQEMEILYKKEKEEADLL---LEQQRL--DYE--SKLQALQK--QV-ET---RSLA- 4 ( 662) ---LQEMEILYKKEKEEADLL---LEQQRL--DAD--S-----DS--GD-DSDKRSC--- 5 ( 688) QRLYADSDSGDDSDKRSCEESWRLISSLRE--QLPPTTVQTIVKRCGLP-SSGKRRA... // 0 ( 666) --IENKLKDLLAEKEKFEEE---RLREQ--------QEIELQK---KRQEEETFLRVQEE 1 ( 1003) --INNQKAN--HKIEELEKA---KQHLE--------QEIYVNK---KRLEMET-LATKQA 2 ( 671) PSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREANYIA---EELDKRTEYKVTLQ 3 ( 758) --AET------TEEEEEEEE---VPWTQ--------HEFELAQWAFRKWKSHQFTSLRDL 4 ( 701) ---EESWKLITSLREKLPPS---KLQTIV-------KKCGLPS---SGKKREP-IKMYQI 5 ( -) ............................................................ // 0 ( 710) LQ----RLKELNNN----EKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVM 1 ( 1044) LEDHSIRHARILEA----LETEKQKIAKEVQILQQNRNNR.................... 2 ( 728) IP----A-SSLDAN----RKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRD---- 3 ( 799) LWGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPLPPELLPTEMEKTHEDRPFPRTVV 4 ( 744) PQ----R-RRLS-------KDSKWVTISDL-KIQAVKEICY-EVALNDFRHSRQEIEALA 5 ( -) ............................................................ // 0 ( 762) LVAHLEE-QLREKQEMIQLLRRGEVQ-W-VEEEKRDLEGIRESLLRVKEARAGGDEDGEE 1 ( -) ............................................................ 2 ( 775) LYQEWKE-CEEDNPVIRSYFKRADPF-Y-DEQENHSLIGVANVFL............... 3 ( 859) AVE-------------VQDLKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQDESET 4 ( 790) IVKMKELCAMYGKKDPNE---RDSWR-A-VARDVWDTVGVGDEKIEDVMATGKGSTDVDD 5 ( -) ............................................................ // 0 ( 819) LEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEK 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 906) TVTGSDPFYD--RFHWFKLV........................................ 4 ( 845) L-KVHIDKLE-DILQEVKKQNNMKD--EEIKVLRNKMLKMEKVLPLIGSQEQK-SPGSHK 5 ( -) ............................................................ // 0 ( 879) HDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTL-------LEEKQRAFEI 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 900) AKEPVGAGVSSTSENNVSKGDNGELAKEERVSQ--LMNGDPAFRRGRLRWMRQEQIRFKN 5 ( -) ............................................................ // 0 ( 932) LDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKV---- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 958) LQQQEITKQLRRQNVPHRFIPPENRKPRFPFKSNP--KHRNSWSPGTHIIITEDEVIELR 5 ( -) ............................................................ // 0 ( 988) -------RKKEKEILESREKQQREALERAL----ARLERRHSALQ---RHSTLGTEIEEQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1016) IPKDDEARKGNKE--ESQEKGGKGAFKDPQFPWGSQGMRSQDHIQVSKQHINNQQQPPQL 5 ( -) ............................................................ // 0 ( 1034) RQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHH--G 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1074) RWRSNSLNNGQPKSTRCQASASAESLNSHSGHPTADVQTFQAKRHIHQHRQSYCNYNTGG 5 ( -) ............................................................ // 0 ( 1092) TLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKD 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1134) QLEGNAATSYQKQTDKPSH......................................... 5 ( -) ............................................................ // 0 ( 1152) NEKLHNGTIQRKLKYELCRDLLCVLMPEPDAAACANHPLLQQDLVQLSLDWKTEIPDLVL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1212) PNGVQVSSKFQTTLVDMIYFLHGNMEVNVPSLAEVQLLLYTTVKVMGDSGHDQCQSLVLL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1272) NTHIALVKEDCVFYPRIRSRNIPPPGAQFDVIKCHALSEFRCVVVPEKKNVSTVELVFLQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1332) KLKPSVGSRNSPPEHLQEAPNVQLFTTPLYLQGSQNVAPEVWKLTFNSQDEALWLISHLT 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1392) RL 1 ( -) .. 2 ( -) .. 3 ( -) .. 4 ( -) .. 5 ( -) .. //