# 0 KIAA1708, 1657 aa # 1 KIAA0449 (1628 aa) # 2 KIAA0359 (760 aa) # 3 KIAA0531 (999 aa) # 4 KIAA1405 (993 aa) # 5 KIAA1448 (1179 aa) // exp sw-scr id% from to 1 2.6e-101 6324 60.1 13 1603 2 3.9e-09 900 32.1 22 589 3 1.2e-08 963 27.7 46 876 4 4e-08 819 28.2 41 787 5 1.8e-06 784 26.3 30 975 // 0 ( 1) PDESSVRVAVRIRPQLAKE--KIEGCHI-----CTSV-TPGEPQVFLGKDKA-------- 1 ( 13) .....VKVAVRIRPQLSKE--KIEGCHI-----CTSV-TPGEPQVLLGKDKA-------- 2 ( 22) ....SVRVVVRCRPMNGKE--KAASYDK-----VVDV-DVKLGQVSVKNPKGTAHEMPKT 3 ( 46) PAECSIKVMCRFRPLNEAE--ILRGDKF-----IPKF-K-GDETVVIGQGKP-------- 4 ( -) ............................................................ 5 ( 30) ...ASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPK---EAPKS-------- // 0 ( 45) FTFDYVF-----DID---SQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-G 1 ( 52) FTYDFVF-----DLD---TWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTM-G 2 ( 70) FTFDAVY-----DWN---AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEG 3 ( 89) YVFDRVL-----PPN---TTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEG 4 ( 41) .................................QGVTEGYNGTIFAYGQTGSGKSFTM-Q 5 ( 76) FSFDYSYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTM-M // 0 ( 96) TGFDVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDL 1 ( 103) TGFDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDL 2 ( 122) IRGD----PEKRGVIPNSFDHIFTHISRSQN---------QQYLVRASYLEIYQEEIRDL 3 ( 141) KLHDPQL----MGIIPRIAHDIFDHI-----YSMDENL---EFHIKVSYFEIYLDKIRDL 4 ( 67) GLPDP---PSQRGIIPRAFEHVFESVQCAENTK---------FLVRASYLEIYNEDVRDL 5 ( 135) GKQE----ESQAGIIPQLCEELFEKIND-------NCNEEMSYSVEVSYMEIYCERVRDL // 0 ( 156) FDTTRDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQM 1 ( 163) FDSTRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQM 2 ( 169) L--SKD---QTKRLELKERPDT--GVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNM 3 ( 189) LDVS--------KTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNM 4 ( 115) LGA----DTKQK---LELKEHPEKGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLM 5 ( 184) LNP-------KNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNM // 0 ( 216) NVQSSRSHAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSE 1 ( 223) NVQSSRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSE 2 ( 222) NEHSSRSHAIFVITIE----CSEVGLDGENHIRV--------------GKLNLVDLAGSE 3 ( 241) NEHSSRSHSIFLINIKQENV--------ETEKK-------------LSGKLYLVDLAGSE 4 ( 168) NKDSSRSHSIFTISIEMS----------AVDER--------GKDHLRAGKLNLVDLAGSE 5 ( 237) NETSSRSHAVFTI------VFTQKKHDNETN--LSTEKV---------SKISLVDLAGSE // 0 ( 276) RLKRTGATGERAKEGISINCGLLALGNVISALGD---KSKRATHVPYRDSKLTRLLQDSL 1 ( 283) RLKRTGATGERAKEGISINCGLLALGNVISALGD---QSKKVVHVPYRDSKLTRLLQDSL 2 ( 264) RQAKTGAQGERLKEATKINLSLSALGNVISALVD-----GKSTHIPYRDSKLTRLLQDSL 3 ( 280) KVSKTGAEGAVLDEAKNINKSLSALGNVISALAE---GTK--THVPYRDSKMTRILQDSL 4 ( 210) RQSKTGATGERLKEATKINLSLSALGNVISALVD-----GRCKHVPYRDSKLTRLLQDSL 5 ( 280) RADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENL // 0 ( 333) GGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRL 1 ( 340) GGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARL 2 ( 319) GGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARL 3 ( 335) GGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKK------KY 4 ( 265) GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKL 5 ( 340) GGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRL // 0 ( 393) QMELMEYKTGKRIIDE---EGVESIN---DMFH-ENAMLQTE--NNNLRVRIKAMQETVD 1 ( 400) QMELMEYKAGKRVIGE---DGAEGYS---DLFR-ENAMLQKE--NGALRLRVKAMQEAID 2 ( 379) KAQLEKRSIGRRKRREKRREGGGSGGGGEEEEE-EGEEGEEE--GDDKDDYWREQQEKLE 3 ( 389) EKEKEKNKTLKNVIQH---LEME-LN---RWRN-GEAV--PE--DEQISAKDQKNLEPCD 4 ( 325) KAILTQQMSPSSLSAL---LSRQVPP---DPVQVEEKLLPQPVIQHDMEAEKQLIREEYE 5 ( 400) ----------KDLLRA---QGLGDII---DT---SMGSLTSS--PSSCSLSSQVGLTSVT // 0 ( 444) ALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLL-ESEAV------- 1 ( 451) AINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLL-ESEAM------- 2 ( 436) IEKRAIVE------DHSLV-----AEEKMRLLKEKEKKMEDLRREKD-AAEML------- 3 ( 437) N-----TPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEIN-QQSQL------- 4 ( 379) E---RLARLKADYKAEQESRA-RLEEDITAMRNSYDVRLSTLEENLRKETEAVLQVGVLY 5 ( 439) SIQERI--MSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRM-EREAL------- // 0 ( 496) -NENL-RKNLTR-----ATARAPYFSGSSTFSPTI----LSSDKETIEIIDLAKKD-LE- 1 ( 503) -NESL-RRSLSR-----ASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQD-LE- 2 ( 477) -GAKI-KAMESK-----LLVGGKNIVDHTNEQQKI----LEQKRQ--EIAEQKRRE-RE- 3 ( 484) -AEKL-KQQMLDQDELLASTRRDYEKIQEELTRLQ----IENEAAKDEVKEVLQA--LE- 4 ( 435) KAEVMSRAEFAS-----SAEYPPAFQYETVVKPKV----FSTT-DTLPSDDVSKTQ-VSS 5 ( 489) -LAEM-GVAIRE-----DGGTLGVFSPKKTPHLVN----LNEDPLMSECLLYYIKDGIT- // 0 ( 543) ---KLKRKEKRKKKSVAGKEDNTDTDQE-----KKEE--K--GV--SERENN-----ELE 1 ( 554) ---RLKKKEVRQRRKSPEKEAFKKRAKL-----QQEN---------SE-ETD-----ENE 2 ( 522) ---IQQQMESRDEETLELKETYSSLQQEVDIKTKKLK--K--LF--SKLQAV-----KAE 3 ( 535) ---ELAVNYDQKSQEV---EDKTRANEQ-----LTDELAQ--KT--TTLTTT-----QRE 4 ( 484) RFAELPKVEPSKSEISLGSSESSSLEET-----SVSE--AFPGP--EEPSNV-----EVS 5 ( 537) ---RVGQADAERRQ------DIVLSGAH-----IKEE--H--CIFRSERSNSGEVIVTLE // 0 ( 584) VEESQE--VSDHEDEEEEE-----EEEEDDIDGG--ES------------SDESDSESDE 1 ( 591) AEEEEE--ERDESGCEEEE-----GREDEDEDSGSEES------------LVDSDSDPEE 2 ( 568) IHDLQE----EHIKERQEL-----EQTQNEL............................. 3 ( 575) LSQLQE--LSNHQKKRATEILNLLLKDLGEIGGI--IG------------TNDVKTLADV 4 ( 530) MPTEES--RSRYFLDECLG-----QEAAGHLLGE--QNYL----------PQEEPQEVPL 5 ( 579) PCERSETYVNGKRVSQPVQ-----LRSGNRIIMG--KNHVFRFNHPEQARAEREKTPSAE // 0 ( 623) K-A--NYQADLANITCEIAIKQKLIDELENSQKRLQTL----KKQYEEKLMMLQHKIRDT 1 ( 632) KEV--NFQADLADLTCEIEIKQKLIDELENSQRRLQTL----KHQYEEKLILLQNKIRDT 2 ( -) ............................................................ 3 ( 619) N-G--VIEEEFTMARLYISKMKSEVKSLVNRSKQLESA----QMDSNRKMNASERELAAC 4 ( 571) Q-GLLGLQDPFAEVEAKLARLSSTVARTDAPQADVPKV----PVQVPAPTDLLEPSDARP 5 ( 632) T-P--SEPVDWTFAQRELLEKQG-IDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDA // 0 ( 676) QLERDQVLQNLGSVESYSEEKAKKVRSE-----YEK----K----LQAMNKELQRLQAAQ 1 ( 686) QLERDRVLQNLSTMECYTEEKANKIKAD-----YEK----R----LREMNRDLQKLQAAQ 2 ( -) ............................................................ 3 ( 672) QLLISQHEAKIKSLTDYMQNMEQK-RRQ-----LEE----S----QDSLSEELAKLRAQE 4 ( 626) EAEAADDFPPRPEVDLASEVALEVVRTAEPGVWLEA----QAPVALVAQPEPLPATAGVK 5 ( 688) DSDSGD-----DSDKRSCEESWKLITSL-----REKLPPSK----LQTIVKKCG-LPSSG // 0 ( 723) KEHARL-----------LKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEK--ARL 1 ( 733) KEHARL-----------LKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQR--RRL 2 ( -) ............................................................ 3 ( 718) KMHE-------------VSFQDKEKEHLTRLQ-DAEEMKKALEQQMESHREAHQKQLSRL 4 ( 682) RESVGMEVAVLTDDPLPVVDQQQVLARLQLLEQQVVGGEQAKNKDLKE--KHKRR--KRY 5 ( 733) KKREPI-----------KMYQIPQRRRLSKDSKWVT-ISDLKIQAVKEICYEVAL--NDF // 0 ( 770) T---ESRRN-----RE---IAQ-LK--------KDQRKRDHQLRLLE--------AQKRN 1 ( 780) V---ETKRN-----RE---IAQ-LK--------KEQRRQEFQIRALE--------SQKRQ 2 ( -) ............................................................ 3 ( 764) RDEIEEKQKIIDEIRD---LNQKLQ--------LEQEKLSSDYNKLK--------IEDQE 4 ( 738) A---DERRK-----QL---VAA-LQ--------NSDEDSGDWV-LLN--------VYDSI 5 ( 779) R---HSRQE-----IEALAIVK-MKELCAMYGKKDPNERDSWRAVARDVWDTVGVGDEKI // 0 ( 802) QEVVLRRK-TEEVTALRRQVRPMSDKVAGKVTRKLSS----SDAPAQD-TGSSAAAVETD 1 ( 812) QEMVLRRK-TQEVSALRRLAKPMSERVAGRAGLKPPM----LDSGAEV-SASTTSSEAES 2 ( -) ............................................................ 3 ( 805) REMKLE-K-LLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELD 4 ( 769) QEEV-RAK-SKLLEKMQRKLR....................................... 5 ( 830) EDVMATGKGSTDVDDLKVHIDKLED-ILQEVKKQNNM----KDEEIKV-LRNKMLKMEKV // 0 ( 856) ASRTG--A---QQKMRIPVARVQALPTPA-TNGNR---KKYQRKGLTGRVFISKTARMKW 1 ( 866) GARSV--SSIVRQWNRKINHFLGDHPAPT-VNGTRPARKKFQKKG-ASQSF-SKAARLKW 2 ( -) ............................................................ 3 ( 863) NDDGGGSA---AQKQKI........................................... 4 ( -) ............................................................ 5 ( 884) LPLIG--S---QEQ-KSPGSHKAKEPVGAGVSSTS---ENNVSKGDNGE--LAKEERVS- // 0 ( 907) QLLERRVTDIIMQKMTISNMEADMNRLLK-QREELTK--RREKLSKRREKIVKENGEGDK 1 ( 921) QSLERRIIDIVMQRMTIVNLEADMERLIK-KREELFL--LQEALRRKRERLQAESPEEEK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 932) QLMN---GDPAFRRGRLRWMRQEQIRFKNLQQQEITKQLRRQNVPHR............. // 0 ( 964) NVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYL 1 ( 978) GLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1024) LDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDAL 1 ( 1038) LDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQAL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1084) LGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKP---KNKARRRT 1 ( 1098) IYNVQQ-------ENGYASTDEEI---SEFSEGSFSQSFTMK--GSTSHDDFKFKSEPKL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1141) TTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGL 1 ( 1146) SAQMKAVSAECLGPPLDISTKN--ITKSLASLVEIKEDGVGFSVRDPYYRDR-VSRTVSL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1201) PSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPP 1 ( 1203) PTRGSTFPRQS-----RATETSPLTRRKSYDRGQPIRS-----TDVG-----FTPPSSPP 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1261) SRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPL 1 ( 1248) TRPRNDRNVFSRLTSNQSQGSAL-DK-----------------GIISPVGGAKGARTAPL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1321) QCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCN 1 ( 1290) QCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCS 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1381) YTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQI 1 ( 1350) HSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQGEHQINQI 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1441) ALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDH 1 ( 1410) ALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDLVVTGSKDH 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1501) YIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQ 1 ( 1470) YVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELIQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1561) QVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNST 1 ( 1530) QIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICTNAK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1621) HIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN 1 ( 1590) HIFTASSDCRVKLW....................... 2 ( -) ..................................... 3 ( -) ..................................... 4 ( -) ..................................... 5 ( -) ..................................... //