# 0 KIAA0465, 4433 aa # 1 KIAA1251 (1483 aa) # 2 KIAA0728 (1637 aa) # 3 KIAA1011 (3541 aa) # 4 KIAA1262 (1362 aa) # 5 KIAA0336 (1635 aa) // exp sw-scr id% from to 1 0 9431 100.0 1 1475 2 5.2e-172 7328 67.1 1 1637 3 1.1e-10 1045 19.6 77 3378 4 1.7e-06 661 19.4 13 1329 5 0.0002 555 20.7 1 1559 // 0 ( 1) KNTISVKAVCDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNK 1 ( 1) KNTISVKAVCDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) DAIEMASRVEQSYQKVMALWHQLHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECH 1 ( 61) DAIEMASRVEQSYQKVMALWHQLHVNTKSLISWNYLRKDLDLVQTWNLEKLRSSAPGECH 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 121) QIMKNLQAHYEDFLQDSRDSVLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAK 1 ( 121) QIMKNLQAHYEDFLQDSRDSVLFSVADRLRLEEEVEACKARFQHLMKSMENEDKEETVAK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 181) MYISELKNIRLRLEEYEQRVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSD 1 ( 181) MYISELKNIRLRLEEYEQRVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQEDLQQLRSD 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 241) LDAVSMKCDSFLHQSPSSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQ 1 ( 241) LDAVSMKCDSFLHQSPSSSSVPTLRSELNLLVEKMDHVYGLSTVYLNKLKTVDVIVRSIQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 301) DAELLVKGYEIKLSQEEVVLADLSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVV 1 ( 301) DAELLVKGYEIKLSQEEVVLADLSALEAHWSTLRHWLSDVKDKNSVFSVLDEEIAKAKVV 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 361) AEQMSRLTPERNLDLERYQEKGSQLQERWHRVIAQLEIRQSELESIQEVLGDYRACHGTL 1 ( 361) AEQMSRLTPERNLDLERYQEKGSQLQERWHRVIAQLEIRQSELESIQEVLGDYRACHGTL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 421) IKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIV 1 ( 421) IKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIV 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 481) KDYELQLMTYKAFVESQQKSPGKRRRMLSSSDAITQEFMDLRTRYTALVTLTTQHVKYIS 1 ( 481) KDYELQLMTYKAFVESQQKSPGKRRRMLSSSDAITQEFMDLRTRYTALVTLTTQHVKYIS 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 541) DALRRLEEEEKVVEEEKQEHVEKVKELLGWVSTLARNTQGKATSSETKESTDIEKAILEQ 1 ( 541) DALRRLEEEEKVVEEEKQEHVEKVKELLGWVSTLARNTQGKATSSETKESTDIEKAILEQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 601) QVLSEELTTKKEQVSEAIKTSQIFLAKHGHKLSEKEKKQISEQLNALNKAYHDLCDGSAN 1 ( 601) QVLSEELTTKKEQVSEAIKTSQIFLAKHGHKLSEKEKKQISEQLNALNKAYHDLCDGSAN 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 661) QLQQLQSQLAHQTEQKTLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQK 1 ( 661) QLQQLQSQLAHQTEQKTLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 721) NQSDLKDLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREK----LHQAKEQY 1 ( 721) NQSDLKDLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREK----LHQAKEQY 2 ( -) ............................................................ 3 ( 77) .........................................VSALWEKWLSLLEAAKEWE 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 777) ---EALQEETRVAQKELE-EAVT-SALQQETEKSKAAKELAENKKKIDALLDWVTSVGSS 1 ( 777) ---EALQEETRVAQKELE-EAVT-SALQQETEKSKAAKELAENKKKIDALLDWVTSVGSS 2 ( -) ............................................................ 3 ( 96) MWCEELKQEWKFVSEEIEREAIILDNLQEELPEISKTKE-AATTEELSELLDCLCQYGEN 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 832) --GGQLLTNL--PGMEQLSGASLEKGALDTTDGYMGV-------NQAPEKLDKQCEMMKA 1 ( 832) --GGQLLTNL--PGMEQLSGASLEKGALDTTDGYMGV-------NQAPEKLDKQCEMMKA 2 ( -) ............................................................ 3 ( 155) VEKQQLLLTLLLQRIRSIQNVPESSGAVETVPAFQEITSMKERCNKLLQKVQKNKELVQT 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 881) ----RH---QELLSQQQNFILATQSAQ--AFLDQHGHNLTPEEQQMLQQK--------LG 1 ( 881) ----RH---QELLSQQQNFILATQSAQ--AFLDQHGHNLTPEEQQMLQQK--------LG 2 ( -) ............................................................ 3 ( 215) EIQERHSFTKEIIALKNFFQQTTTSFQNMAFQDHPEKSEQFEELQSILKKGKLTFENIME 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 924) ELKEQYSTSLAQSEAELK-QVQTLQDELQKFLQDHKEFESWLERS-----EKELENMHKG 1 ( 924) ELKEQYSTSLAQSEAELK-QVQTLQDELQKFLQDHKEFESWLERS-----EKELENMHKG 2 ( -) ............................................................ 3 ( 275) KLRIKYSEMYTIVPAEIESQVEECRKALEDI--DEKISNEVLKSSPSYAMRRKIEEINNG 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 978) GSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVLDMENSFKEGKEPSEIGNLVKD 1 ( 978) GSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVLDMENSFKEGKEPSEIGNLVKD 2 ( -) ............................................................ 3 ( 333) LHNVEKMLQQKSKNIEKAQEIQKKMWDELDLWHSKLNELDSEVQDIVEQDPGQAQEWM-D 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1038) KLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLSDTVA 1 ( 1038) KLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSADSLQAWMQACEANVEKLLSDTVA 2 ( -) ............................................................ 3 ( 392) NLMIPFQQYQQVSQRAECRTSQLNKATVKMEEYSDLLKSTEAWIE----NTSHLLANPAD 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1098) SDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDH--RHVQETTDSI 1 ( 1098) SDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDIMEIEGEPAPDH--RHVQETTDSI 2 ( -) ............................................................ 3 ( 448) YDSLRTLSHHASTVQMALEDSEQKHNL--LHSIFMDLEDLSIIFETDELTQSIQELSNQV 4 ( -) ............................................................ 5 ( 1) ...............................ELEKEIEELRSKP--------VTEGTGDI // 0 ( 1156) LSHFQSLSYSLAER--SSLLQKAIAQSQSVQESLESLLQSIGEVEQNLEGKQVSSLSSGV 1 ( 1156) LSHFQSLSYSLAER--SSLLQKAIAQSQSVQESLESLLQSIGEVEQNLEGKQVSSLSSGV 2 ( -) ............................................................ 3 ( 506) TALQQKIMESLPQ------IQRMADDVVAIESEVKSMEKRVSKIKTILLSKEIFDFSP-- 4 ( -) ............................................................ 5 ( 22) IK-------ALTERLDALLLEKAETEQQCLSLKKENI-----KMKQEVEDS-VTKMGDAH // 0 ( 1214) IQEALATNMKLKQDIARQKSSL-EATREMVTRFMETADSTTAAVLQGKLAEVSQRFEQLC 1 ( 1214) IQEALATNMKLKQDIARQKSSL-EATREMVTRFMETADSTTAAVLQGKLAEVSQRFEQLC 2 ( -) ............................................................ 3 ( 558) -EEHLKHGEVILENIRPMKKTIAEIVSYQVELRLPQTGMKPLPVFQ-RTNQLLQDIKLLE 4 ( -) ............................................................ 5 ( 69) -KELEQSHINYVKEIENLKNEL-MAVR---SKYSEDK-----ANLQKQLEEAMNTQLELS // 0 ( 1273) LQ---QQEKESSLKKLLPQAEMFEHLSGKLQQFMENKSRMLASGNQ-PDQDITHFFQQIQ 1 ( 1273) LQ---QQEKESSLKKLLPQAEMFEHLSGKLQQFMENKSRMLASGNQ-PDQDITHFFQQIQ 2 ( -) ............................................................ 3 ( 616) NV---TQEQNELLKVVIKQTNEWDEEIENLKQILNNYSAQFSLEHMSPDQ--ADKLPQLQ 4 ( -) ............................................................ 5 ( 119) EQLKFQNNSEDNVKKL--QEEIEKIRPGFEEQILYLQKQLDATTDE-KKETVTQL-QNII // 0 ( 1329) ELNLEMEDQQENLDTL-EHLVTELSSCGFALDLCQHQDRVQN-LRKDFTELQKTVKER-- 1 ( 1329) ELNLEMEDQQENLDTL-EHLVTELSSCGFALDLCQHQDRVQN-LRKDFTELQKTVKER-- 2 ( -) ............................................................ 3 ( 671) GEIERMEKQILSLNQRKEDLLVDLKAT--VLNLHQHLKQEQEGVERD--RLPAVTSEEGG 4 ( -) ............................................................ 5 ( 175) EAN--SQHYQKNINSL-QEELLQLKAI--------HQEEVKE-L---MCQIEASAKEH-- // 0 ( 1385) --EKDASSCQEQLDEFRKLVRTFQKWL-KET--EGSIPPTETSMSAKELEKQI----EHL 1 ( 1385) --EKDASSCQEQLDEFRKLVRTFQKWL-KET--EGSIPPTETSMSAKELEKQI----EHL 2 ( -) ............................................................ 3 ( 727) VAERDAS--ERKLN--RRGSMSYLAAV-EEEVEESSVKSDNGDEKAEPSPQSWSSLWKHD 4 ( -) ............................................................ 5 ( 218) --EAEINKLNELKENLVKQCEASEKNIQKKY--ECELENLRKATSNANQDNQI----CSI // 0 ( 1436) KSLLDDWASK--GTLVEEI-NCKGTSLENLIMEITAPDSQGKTDLT-----EIQCDMSDV 1 ( 1436) KSLLDDWASK--GTLVEEI-NCKGTSLENLIMEITAPDSQGKT................. 2 ( -) ............................................................ 3 ( 782) KDMEEDRASSSSGTIVQEA-YGKISTSDNSMAQILTPDSLNTEQGP-----E--CSLRPN 4 ( -) ............................................................ 5 ( 270) --LLQE------NTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQ // 0 ( 1488) NLKYEKLGGVLHERQESLQA---ILNRMEEVHKEANSVLQ-----------WLESKEEVL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 834) QTEEGTTPPIEADTLDSSDAQGGLEPRVEKTRPEPTEVLHACKTQVAELELWLQQANVAV 4 ( -) ............................................................ 5 ( 322) HIKDE----FFHER-EDLEF---KINELLLAKEEQGCVIE-----------KLKSELAGL // 0 ( 1534) K--SMDA-MSSPTKTETVKAQA-----ESNKAFLAELEQN-----SPKIQKVKEALAGLL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 894) EPETLNADMQQVLEQQLVGCQAMLTEIEHKVAFLLETCKDQGLGDNGATQHEAEALSLKL 4 ( -) ............................................................ 5 ( 363) N--KQFC-YTVEQHNREVQSLK-----EQHQKEISELNET-----FLS-DSEKEKLTLMF // 0 ( 1581) VTYPNSQEAENWKKIQEELNSRWERATEVTVARQRQLEESASHLACFQAAESQL----RP 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 954) KTVKC-----NLEKVQMMLQEKHSEDQHPTILKKSSEPEHQEALQPVNLSELESIVTERP 4 ( -) ............................................................ 5 ( 409) EIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKIS--QEFESMK----QQ // 0 ( 1637) WLM-EKELMMGVLGPLSIDPNMLNAQKQQVQFMLKEFEARRQ-----QHE----QLNEAA 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1009) QFSRQKDFQQQQV--LELKPM---EQKDFIKFI--EFNAKKMWPQYCQHDNDTTQESSAS 4 ( -) ............................................................ 5 ( 463) QAS-DVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQE-----LVP----ELENTI // 0 ( 1687) QGILTGPGDVSLSTSQ---VQKELQ----SINQKWVELTDKLNSR---------SSQI-- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1062) NQASSPENDVPDSILS---PQGQ-------NGDKWQYLHHELSSKIKLPLPQLVEPQVST 4 ( -) ............................................................ 5 ( 513) KNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNS---------HEEM-- // 0 ( 1729) DQAIVKSTQYQELLQDLSEKVRAVGQRLS--VQSAISTQPEAVKQQLEETSEIRSDLEQL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1112) NMGILPSVTMYNFRYPTTEELKTYTTQLEDLRQEASNLQ---TQENMTEEAYINLDKKLF 4 ( -) ............................................................ 5 ( 562) DNFHKKCEREERLILELGKKVEQTIQYNSE-LEQKVNELTGGLEETLKEKDQNDQKLEKL // 0 ( 1787) DHEVK----EAQTLCDELSVL-IGEQY-LKDELKKRL--ETVALPLQGLEDLA-ADRINR 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1169) ELFLT----LSQCLSSVEEMLEMPRLY-REDGSGQQVHYETLALELKKLYLAL-SDKKGD 4 ( -) ............................................................ 5 ( 621) MVQMKVLSEDKEVLSAEVKSL-YEENNKLSSEKKQLS--RDLEVFLSQKEDVILKEHITQ // 0 ( 1838) LQAALA----STQQFQQMFDELRTWLDDKQSQQA-KNCPISAKLERLQSQLQENEEFQKS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1223) LLKAMTWPGENTNLLLECFDNLQVCLE--HTQAA-AVC----RSKSLKAGLDYNRSYQ-- 4 ( -) ............................................................ 5 ( 678) LEKKL-------QLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDV // 0 ( 1893) LNQHSGSYEVIVAEGESLLLSVPP------GEEKRTLQNQ----LVELKNHWEELSKKTA 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1274) -NEIKRLYHQLIKSKTSLQQSLNEISGQSVAEQLQKADAY----TVELENA-ESRVAKLR 4 ( -) ............................................................ 5 ( 731) VN-------VLQAVGESL---AKI------NEEKCNLAFQRDEKVLELEKEIKCLQEESV // 0 ( 1943) ----DRQSRLKDCMQKAQKYQWHVEDLVP--WIEDCKAKMSELRVTLDPVQLESSLLRSK 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1328) ----DEGERLHLPYALLQEV-YKLEDVLDSMWGM-LRARYTELSSPFVTESQQDALLQGM 4 ( -) ............................................................ 5 ( 775) VQCEELKSLLRDYEQEKVLLRKELEEIQS--EKEALQSDLLEMKNANEKTRLENQNL--L // 0 ( 1997) AMLNEVEKRRSLLEILNSAADILINSSEA-----DEDGIRDEKAGINQNMDAVTEELQAK 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1382) VELVKIGKEK-----LAHGHLKQTKSKVA-----LQAQIENHKVFF-QKLVADMLLIQAY 4 ( -) ............................................................ 5 ( 831) IQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVK // 0 ( 2052) TGSLEEMTQRLREFQESFKNIEKKVEGAKHQ---LEIFDALGSQACSNKNLEKLRAQ--- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1431) SAKILPSLLQNRETFWAEQVTEVKILEEKSRQCGMKLQSLLQKWEEFDENYASLEKD--- 4 ( -) ............................................................ 5 ( 891) NDPL----SSVKELEEKIENLEKECKEKEEK---INKIKLVAVKA--KKELDSSRKETQT // 0 ( 2106) -QEVLQALEPQVDYLRNFTQGLVEDAPDGSDASQLLHQAEVAQQEFL-EV-KQRVNS-GC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1488) -LEILISTLPSVSLVEETEERLVERISFYQQIKRNIGGKHARLYQTLNEG-KQLVASVSC 4 ( -) ............................................................ 5 ( 942) VKEELESLRSEKDQLSASMRDLIQGAESYKN---LLLEYE-KQSEQL-DVEKERANN--- // 0 ( 2162) VMMENKLEGIG-QFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLN--K 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1546) PELEGQIAKLEEQWLSLNKKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWK 4 ( -) ............................................................ 5 ( 994) -------------FEHRIEDLTRQLRNSTLQCE---TINSDNEDLLARIETLQSNAK--L // 0 ( 2219) IHVLKL--DIEASEAECRHMLEEEGTLDLLG-LKRELEALNKQCGKLTERG----KARQE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1606) EQSLNVSQDLDTIRSNINNFFEFSKEVDEKSSLKTAVISIGNQLLHLKETDTATLRASLA 4 ( -) ............................................................ 5 ( 1036) LEVQIL--EVQRAKA----MVDKE----------LEAEKLQKE-QKIKEHA----TTVNE // 0 ( 2272) QLE----LTLGRVEDFYRKLKGLNDATTAAEEA--EALQWVVGTEVEIINQQ-------L 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1666) QFEQKWTMLITQLPDIQEKLHQLQMEKLPSRKAITEMISWMNNVEHQTSDEDSVHSPSSA 4 ( -) ............................................................ 5 ( 1075) LEE----LQVQLQKEKKQLQKTMQELELVKKDA--Q--------QTTLMNME-------I // 0 ( 2319) ADFK-MFQKEQVDPLQMKLQQ--VNGLGQGL-IQSAGKDC---DVQGLE---HD------ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1726) SQVKHLLQKHKEFRMEMDYKQWIVDFVNQSL-LQLS--TC---DVESKR---YERTEFAE 4 ( -) ............................................................ 5 ( 1114) ADYE-RLMKELNQKLTNKNNK--IEDLEQEIKIQKQKQETLQEEITSLQSSVQQ------ // 0 ( 2363) -MEEINARWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLADTEELIANQKPPSAE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1777) HLGEMNRQWHRVHGMLNRKIQHLEQLLESITESENKIQILNNWLEAQEERLKTLQKPESV 4 ( -) ............................................................ 5 ( 1165) -YEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLK---GELEASQQQVEVYKIQLAE // 0 ( 2422) YKVVKAQIQEQ-----KLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1837) ISVQKLLLDCQ-----DIENQLAIKSKA-LDELK-QSYLTLESGAVPLLEDTASRIDELF 4 ( -) ............................................................ 5 ( 1221) ITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEEC-RAAK----AEQATVTSEFESYK // 0 ( 2477) SRWTELLSKAAAR---QKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPVGT---Q 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1890) QKRSSVLTQVNQL---KTSMQSVLQEWKIYDQLYDEVNMMTIRFWYCMEHSKPVVL---S 4 ( 13) ..................QREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDA---E 5 ( 1276) VRVHNVLKQQKNKSMSQAETEG----AKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQ // 0 ( 2531) TAKIQQQII--RHKALNEEIVNRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRY 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 1944) LETLRCQVE--NLQSLQDEAESSEGSWEK-LQEVIGKLKGLCPSVAEIIEEKCQNTHKRW 4 ( 52) STAVHLEAL--KKLALALQ--ERKYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRW 5 ( 1332) TLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQS-------ENMMMKSEH-----TQT // 0 ( 2589) ADIT-VTSSKALRTL--EQARQLATKFQSTYEELTGWLREVEEELATSGGQSPTG----E 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2001) TQVN-QAIADQLQKA--QSLLQLWKAYSNAHGEAAARLKQQEAKFQQLANISMSGNNLAE 4 ( 108) FQLEDLIKRKIQVSV--TNLEELNV-VQSRFQELMEWAEEQQPNIAEALKQSPPP----D 5 ( 1380) VSQL-TSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNE-PTT----R // 0 ( 2642) QIPQFQQRQKELKKEVMEHRLVLDT-VNEVSRALLELVPWRAREGLDKLVSDANEQYKLV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2058) ILPPALQDIKELQHDVQKTKEAFLQ-----NSSVLDRLPQPAESSTHMLLP--GPLHSL- 4 ( 161) MAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADL-GLNERQVIQKALSDAQSHVNCL 5 ( 1434) SPVSSQQSLKNLRERRNTDLPLLD--MHTVTR--------EEGEGMETTDTESVSSASTY // 0 ( 2701) SDTIGQRVDEIDAAIQ-RSQQYEQAADAELAW-VAETKRKLMALGPIRLEQDQTTAQLQV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2110) -----QRAAYLEKMLLVKANEFEFV----LSQ-FKDFGVRLESLKGLIMHEEENLDRLHQ 4 ( 220) SDLVGQRRKYLNKALS-EKTQFLMAVFQATSQ-IQQHERKIMFREHICLLPDDVSKQVKT 5 ( 1484) TQSLEQLLNSPETKLE-PPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILME // 0 ( 2759) QKAFSID-IIRHKDSMDEL---FSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLNS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 2160) QEKENPDSFLNHVLALTAQSPDIEHLNEV--SLKLPLSDVAVKTLQNMNRQWIRATATAL 4 ( 278) CKSAQAS-LKTYQNEVTGL---WAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCS 5 ( 1543) QIKLLKS-EIRRLERNQE.......................................... // 0 ( 2815) ERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDH-E--QLRQQQEEMRQL 1 ( -) ............................................................ 2 ( 1) ....................EELWPWLTETQSIISQLPAPALEY-E--TLRQQQEEHRQL 3 ( 2218) ERCSELQGIG-LNEKFLYCCEK---WIQLLEKIEEALKVDVANSLP--ELLEQQKTYKML 4 ( 334) HRLQELEKNLVSRKHFKEDFDKACHWLKQ--ADIVTFPEINLMN-ESTELHTQLAKYQNI 5 ( -) ............................................................ // 0 ( 2872) RESIAEHKPHIDKLLKIGPQ-LKELNPEEG--EMVEEKYQKAENMYAQIKEEVRQRALAL 1 ( -) ............................................................ 2 ( 38) RELIAEHKPHIDKMNKTGPQ-LLELSPGEG--FSIQEKYVAADTLYSQIKEDVKKRAVAL 3 ( 2272) EAEVSINQTIADSYVTQSLQ-LLDTTEIENRPEFITE-FSKLTDRWQNAVQGVRQRKGDV 4 ( 391) LEQSPEYENLLLTLQRTGQTILPSLNEVDH--SYLSEKLNALPRQFNVIVALAKDKFYKV 5 ( -) ............................................................ // 0 ( 2929) DEAVSQSTQITEFHDKIEPMLETLENLSSR-LR-MPPLIPAEVDKIRECISDNKSATVEL 1 ( -) ............................................................ 2 ( 95) DEAISQSTQ---FHDKIDQILESLERIVER-LR-QPPSISAEVEKIKEQISENKNVSVDM 3 ( 2330) DGLVR---QWQDFTTSVENLFRFLTDTSHL-LSAVKGQERFSLYQTRSLIHELKNKEIHF 4 ( 449) QEAILARK---EYASLIELTTQSLSELEAQFLR-MSK-VPTDL-AVEEALSLQDGCRAIL 5 ( -) ............................................................ // 0 ( 2987) EKLQPSFEALKRRGEELIGRSQGADKDLAAKE-IQDKLDQMVFFWEDIKARAEEREIKFL 1 ( -) ............................................................ 2 ( 150) EKLQPLYETLKQRGEEMIARSGGTDKDISAKA-VQDKLDQMVFIWENIHTLVEEREAKLL 3 ( 2386) QRRRTTCALTLEAGEKLLLTT-----DLKTKESVGRRISQLQDSWKDMEPQLAEMIKQFQ 4 ( 503) DEVAGLGEAV----DELNQKKEGF-RSTGQPW-QPDKMLHLVTLYHRLKRQTEQR-VSLL 5 ( -) ............................................................ // 0 ( 3046) DVLELA----EKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDG 1 ( -) ............................................................ 2 ( 209) DVMELA----EKFWCDHMSLIVTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDG 3 ( 2441) STVET--------WDQCEKKIKELKSRLQVLKA-QSEDPLPELHEDLHNEKELIKELEQS 4 ( 556) EDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEK--LKMYHSLAGSLQD--SG 5 ( -) ............................................................ // 0 ( 3102) LH---EELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKLEDAMQ 1 ( -) ............................................................ 2 ( 265) LQ---EELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQ 3 ( 2492) LASWTQNLKELQTMKADLTRHVLVEDVMVLKEQIEHLHRQWEDLCLRVAIRKQEIEDRLN 4 ( 612) I-----VLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMV 5 ( -) ............................................................ // 0 ( 3159) AAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIE---- 1 ( -) ............................................................ 2 ( 322) AAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIE---- 3 ( 2552) TWVVFNEKNKELCAWLVQMENKVLQTADISIEEMIEKLQKDCMEEINL-FSENKLQ---- 4 ( 667) QSIDFQTEMSRSLDWLRR--VKAELSGPVYLDLN-LQDIQEEIR--KIQIHQEEVQSSLR 5 ( -) ............................................................ // 0 ( 3215) -MEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQF 1 ( -) ............................................................ 2 ( 378) -MERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQF 3 ( 2607) -LKQMGDQ----LIKASNKSRAAEIDDKLNKINDRWQHLFDVIGSRVKKLKETFAFIQQL 4 ( 722) IMNALSHKEKEKFTKAKELISADL-EHSLAELSELDGDIQEALRTRQATLTEIYSQCQRY 5 ( -) ............................................................ // 0 ( 3274) QHALEELMSWLTHTEELLDAQRPISG-D---PKVIEVELAKHHVLKNDVLAHQATVETVN 1 ( -) ............................................................ 2 ( 437) QHALDELLAWLTHTEGLLSEQKPVGG-D---PKAIEIELAKHHVLQNDVLAHQSTVEAVN 3 ( 2662) DKNMSNLRTWLARIESELS--KPVVY-DVCDDQEIQKRLAEQQDLQRDIEQHSAGVESVF 4 ( 781) YQVFQAANDWLEDAQEML--QLAGNGLD---VESAEENLKSHMEFFSTEDQFHSNLEELH 5 ( -) ............................................................ // 0 ( 3330) K---AGNELLESS---AGD-DASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGF 1 ( -) ............................................................ 2 ( 493) K---AGNDLIESS---AGE-EASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGF 3 ( 2719) N---ICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRMKIEETWRLWQKF 4 ( 836) SLVATLDPLIKPT---GKE-DLEQKVASLELRSQ---RMSRDSGAQVDLLQRCTAQWHDY 5 ( -) ............................................................ // 0 ( 3383) ---HSEIEDFLLELTRMESQLSA-SKPTGG--LPETAREQLDTHMELYSQLKAKEETYNQ 1 ( -) ............................................................ 2 ( 546) ---HGEIEDLQQWLTDTERHLLA-SKPLGG--LPETAKEQLNVHMEVCAAFEAKEETYKS 3 ( 2776) LDDYSRFEDWLKSAER-----TA-ACPNSSEVLYTSAKEELKRFEAFQRQIHERL-TQLE 4 ( 889) ---QKAREEVIELMNDTEKKLSEFSLLKTS--SSHEAEEKLSEHKALVSVVNSFHEKIVA 5 ( -) ............................................................ // 0 ( 3437) LLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSL 1 ( -) ............................................................ 2 ( 600) LMQKGQQML-ARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSL 3 ( 2829) LINKQYRRLARENRTDTASRLKQMVHEGNQRWDNLQRRVTAVLRRLRHFTNQREEFEGTR 4 ( 944) LEEKASQLEKTGNDA-SKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKV 5 ( -) ............................................................ // 0 ( 3497) QEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIEL-DQTGNQLK 1 ( -) ............................................................ 2 ( 659) QDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIEL-DKTGTHLK 3 ( 2889) ESILVWLT--EMDLQLTNVEHFSESDADDKMRQLNGFQQEITLNTNKIDQL-IVFGEQLI 4 ( 1003) KKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQ 5 ( -) ............................................................ // 0 ( 3556) ---FLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWL 1 ( -) ............................................................ 2 ( 718) ---YFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWL 3 ( 2946) ---QKSEPLDAVLIEDELEELHRYCQEVFGRVSRFHRRLTSCTPGLEDEKEASENETDME 4 ( 1063) DGAAPTPGEEPPLMQEI-TAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWV 5 ( -) ............................................................ // 0 ( 3613) EDAESHL-DS-----ELEISNDPDKIKLQLSK---HKEFQKTLGGKQPVYDTTI-----R 1 ( -) ............................................................ 2 ( 775) EESEKSL-DS-----ELEIANDPDKIKTQLAQ---HKEFQKSLGAKHSVYDTTN-----R 3 ( 3003) DPREIQT-DSWRKRGESEEPSSPQSLCHLVAP---GHERS---GCETPVSVDSIPLEWDH 4 ( 1122) QETKEYLGNP-----TIEIDAQLEELQILLTEATNHRQNIEKMAEEQKE----------- 5 ( -) ............................................................ // 0 ( 3659) TGRALKEKTLLP-EDSQKLDNFLGE--VRDK-WDTVCGKSVERQHKLEEALL--FSGQFM 1 ( -) ............................................................ 2 ( 821) TGRSLKEKTSLA-DDNLKLDDMLSE--LRDK-WDTICGKSVERQNKLEEALL--FSGQFT 3 ( 3056) TGDVGGSSSHEE-DEEGPYYSALSD--VE-------IPENPEAYLKMTTKTLKASSGKSI 4 ( 1166) --KYLGLYTILPSELSLQLAEVALDLKIRDQIQDKI--KEVEQSKATSQEL----SRQIQ 5 ( -) ............................................................ // 0 ( 3713) DALQALVDWLYKVEPQLAED--QPVHGDLDLVMNLMDAHKVFQKELGKRT---GTVQVLK 1 ( -) ............................................................ 2 ( 875) DALQALIDWLYRVEPQLAED--QPVHGDIDLVMNLIDNHKAFQKELGKRT---SSVQALK 3 ( 3106) SDGHS---WHVPDSPSCPEHHYKQMEGDRNVPPVPPASSTPYKPPYGKLLLPPGT-DGGK 4 ( 1218) KLAKDLTTILTKLKAKT--D--NVVQAKTD--------QKVLGEELDGCN---SKLMELD 5 ( -) ............................................................ // 0 ( 3768) RSGRELIE-NSRDDTTWVK--GQLQELS---TRWDTVCKLSVSKQSRLEQALKQAEVFRD 1 ( -) ............................................................ 2 ( 930) RSARELIE-GSRDDSSWVK--VQMQELS---TRWETVCALSISKQTRLEAALRQAEEFHS 3 ( 3162) EGPRVLNG-NPQQEDGGLA--GITEQQSGAFDRWEMIQAQELHNKLKIKQNLQQ---LNS 4 ( 1263) AAVQKFLEQNGQLGKPLAKKIGKLTELH---QQ--TI-RQAENRLSKLNQAASHLEEYNE 5 ( -) ............................................................ // 0 ( 3822) TVHMLLEWL--SEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNSAVAMGE 1 ( -) ............................................................ 2 ( 984) VVHALLEWL--AEAEQTLRFHGVLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGD 3 ( 3216) DISAITTWLKKTEAELEMLKMAKPPSDIQEIELRVKRLQEILKAFDTYKALVVSVNVSSK 4 ( 1317) MLELILKWI--EKAK............................................. 5 ( -) ............................................................ // 0 ( 3880) VILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWI 1 ( -) ............................................................ 2 ( 1042) TVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWL 3 ( 3276) EFLQTESPES-TELQSRLRQLSLLWEAAQGAVDSWRGGLRQSLMQCQDFHQLSQNLLLWL 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 3940) QWAETTLIQRDQEPIPQNIDRVKALIAEHQTFME---EMTRKQPDVDRVTKTYKRKNIEP 1 ( -) ............................................................ 2 ( 1102) QWAETTLTDKDKEVIPQEIEEVKALIAEHQTFME---EMTRKQPDVDKVTKTYKRRAADP 3 ( 3335) ASAKN---RRQKAHVTDPKADPRALLECRRELMQLEKELVERQPQVD............. 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 3997) T----HAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQ 1 ( -) ............................................................ 2 ( 1159) SSLQSHIPVLDKGRAG-RKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERR 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4053) RKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFI 1 ( -) ............................................................ 2 ( 1218) RKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFI 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4113) DGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVT 1 ( -) ............................................................ 2 ( 1278) DGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPITDADKIEDEVT 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4173) RQVAQCKCAKRFQVEQIGENKYRF------GDSQQLRLVRILRSTVMVRVGGGWMALDEF 1 ( -) ............................................................ 2 ( 1338) RQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEF 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4227) LVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQS 1 ( -) ............................................................ 2 ( 1398) LVKNDPCRAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQA 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4287) NHSCTSMPSSPAT-----------------------------------PASGTKVIPSSG 1 ( -) ............................................................ 2 ( 1458) AQAAS--PQVPATTTPKILHPLTRNYGKPWLTNSKMSTPCKAAECSDFPVPSAEGTPIQG 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4312) SKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASS 1 ( -) ............................................................ 2 ( 1516) SKLR--LPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASS 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4372) RRGSDASDFDLLETQSACSDTS---ESSAAGGQGNSRRGLNKPSKIPTMSKKTTTASPRT 1 ( -) ............................................................ 2 ( 1574) RRGSDASDFDISEIQSVCSDVETVPQTHRPTPRAGSRPSTAKPSKIPTPQRKSP-ASKLD 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 4429) PGPKR 1 ( -) ..... 2 ( 1633) KSSKR 3 ( -) ..... 4 ( -) ..... 5 ( -) ..... //