# 0 KIAA0337, 1609 aa # 1 KIAA1626 (1284 aa) # 2 KIAA0294 (1405 aa) # 3 KIAA1066 (1346 aa) # 4 KIAA0516 (1382 aa) # 5 KIAA1415 (1621 aa) // exp sw-scr id% from to 1 7e-13 790 23.5 6 1280 2 4.8e-12 765 23.8 436 1340 3 8e-09 533 24.0 448 1341 4 1.3e-08 608 23.9 490 1377 5 3.8e-07 374 30.9 5 276 // 0 ( 1) KSRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) GQLEPIPIPAPASPGTRPTLKDLTATLRRAKSFTCSEKPMARRLPRTSALKSSSSELLLT 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 121) GPGAEEDPLPLIVQDQYVQEARQVFEKIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 181) ELSGPESSLTDEGIGADPEPPVAAFCGLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWAL 1 ( 6) ...........................................................M 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 241) VSPETPPTPGALRRRRKVPPSGSGGSEFSNGEAGEAYRSLSDPIPQRHRAATSEEPT--- 1 ( 7) ASSNPPPQPAI---GDQLVPGVPGPSSEAEDDPGEAFE-FDDSDDEEDTSAALGVPSLAP 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 298) GFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHSDW-SVGSEESKGYQEVIQSIVQGPGTL 1 ( 63) ERDTDPPLIHLDSIPVTDPDPAAAPPG--TGVPAWVSNGDAADAAFSGARHSSWKRKSS- 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 357) GRVVDDRIAGKAPKKKSLSDPSRRGELAGPGFEGPGGEPIREVEPMLPPSSSEPILVEQR 1 ( 120) -RRID-RFTFPALEEDVIYDDV---PCESPDAHQPGAE--RNLLYEDAHRAGAPRQAEDL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 417) AEPEEPGATRSRAQSERALPEALPPPATAHRNFHLDPKLADILSPRLIRRGSKKRPARSS 1 ( 173) GWSSSEFESYSEDSGEEAKPEVEVEPAK-HR-VSFQPKL----SPDLTRL--KERYARTK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 477) HQELRRDEGSQDQTGSLSRARPSSRHVRHASVPATFMPIVVPEPPTSVG---PPVAVPEP 1 ( 225) RDILALRVGGRDM-----------QELKHKYDCKMTQLMKAAKSGTKDGLEKTRMAVMRK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 534) IGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVPAPVPVDMPCLPLAAPPSAEAKPPEAAR 1 ( 274) VSFLHR----------KDV-------LGDSE-----EEDMGLLEVSV---SDIKPPA--- 2 ( 436) ...................................................DCKHPEAIL 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 594) PADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQP-ENSVLCD 1 ( 306) PELGPMPEGL---SPQQVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEM-EPKAL-S 2 ( 445) -----TPMPEGLSQQQV-VRRYILGSVVDSEKNYVDALKRILEQYEKPLSEM-EPKVLSE 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 5) ............SERQLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSV--E // 0 ( 653) PSLVDE----IFDQIPELLEHHEQFLEQVRHCMQTW-HAQQKVGALLVQSFSKDVLVNIY 1 ( 361) ARKCQV----VFFRVKEILHCHSMFQIALSSRVAEW-DSTEKIGDLFVASFSKSMVLDVY 2 ( 498) RKL-KT----VFYRVKEILQCHSLFQIALASRVSEW-DSVEMIGDVFVASFSKSMVLDAY 3 ( 448) .....................................................NVVKNDL 4 ( -) ............................................................ 5 ( 51) KGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLK-F-KDKFC-VY // 0 ( 708) SAYIDNFLNAKDAVRVAKEA-R--PAFLKFLEQSMRENKE--KQA---LSDLMIKPVQRI 1 ( 416) SDYVNNFTSAMSIIKKACLT-K--PAFLEFLKRRQVCSPD--RVT---LYGLMVKPIQRF 2 ( 552) SEYVNNFSTAVAVLKKTCAT-K--PAFLEFLKQEQEASPD--RTT---LYSLMMKPIQRF 3 ( 455) IAKVDQLSGEQEVLRGELEAAK--QAKVK-LENRIKELEEELKRV---KSEAII--ARRE 4 ( -) ............................................................ 5 ( 108) EEYCSNH---EKALRLLVEL-NKIPTVRAFLLSCMLLGGR--KTTDIPLEGYLLSPIQRI // 0 ( 760) PRYELLVK-DLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQE-I 1 ( 468) PQFILLLQ-DMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTKS-V 2 ( 604) PQFILLLQ-DMLKNTSKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEVKQIAKA-I 3 ( 507) PKEE--AE-DVSSYLCTESDKIPM---AQR-------------RRFTRVE-MARVLME-R 4 ( 490) .....IVKNDLIAKVDELTCEKDVLQGELEAVKQAKLKLEEKNRELEEELRKARAEAEDA 5 ( 162) CKYPLLLK-ELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQMEKLE----ALEQ-L // 0 ( 818) -EAHIEGME--DLQAPL---RRFLRQEMVIE-V-----KAIGGK----KDRSLFL----- 1 ( 526) -SDRSSLNK--LLTSGQ---RQLLLCETLTETV-----YGDRGQLIKSKERRVFL----- 2 ( 662) NERYLNKL----LSSGS---RYLIRSDDMIE-TVYNDRGEIVKT----KERRVFM----- 3 ( 546) -NQYKERLM--ELQEAV---RWTEMIRASRE-H-----PSVQEK----KKSTIWQ----- 4 ( 545) -RQKAKDDD--DSDIPTAQRKRFTRVEMARV-L-----MERNQY----KERLMELQEAVR 5 ( 216) -QSHIEGWEGSNLTDIC---TQLLLQGTLLK-I-----SA-GNI----QERAFFL----- // 0 ( 857) FTDLIV-CTTLKRKSGSLRRSSMSL-YTAASVIDTASKYKMLW------KLPLE---DAD 1 ( 570) LNDMLV-CANINFKPAN-HRGQLEI----SSLVPLGPKYVVKW------NTALP---QVQ 2 ( 705) LNDVLM-CATVSSRPSHDSR------------VMSSQRYLLKW------SVPLG---HVD 3 ( 585) FFSRLF-SSSSSPPPAKRPYPSVNIHYKSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDD 4 ( 592) WTEMIR-ASRENPAMQEKKRSSIWQ-FFS-RLFSSSSNTT---------KKPEP---PVN 5 ( 256) FDNLLVYCKRKSRVTGSKKST....................................... // 0 ( 906) IIK-GASQAT-NRENIQK---AISRLDEDLT-TLGQMSKLSE-SLGFPH--QSL------ 1 ( 615) VVEVGQDGGTYDKDNV-----LIQHSGAKKA-SASGQAQNKV-YLGPPRLFQEL------ 2 ( 743) AIE-YGSSAG-TGEHSRH---LAVHPPESLA-VVANAKPNKV-YMG-PG--Q-------- 3 ( 644) CTS-SARREQ-KREQYRQ---VREHVRNDD----GRLQACGW-SLPAKY--KQLSPNGGQ 4 ( 637) LKY-NAPTSH-VTPSVKKRSSTLSQLPGDKSKAFDFLSEETEASLASRR--EQK------ 5 ( -) ............................................................ // 0 ( 951) -DDALRDLSAAMH-RDLSEKQALCYALSFPPTKLELCATRPEGTDS--------YIFEFP 1 ( 662) -QDLQKDLAVV--------------------EQITLLISTLHGTYQ--------NLNMTV 2 ( 785) -----------LY-QDL---QNLLHDLNVIGQITQLIGNL-KGNYQ--------NLNQSV 3 ( 692) EDTRMKNVPVPVYCRPLVEKD--------PTMKL-WCAA---GVNL--------SGWRPN 4 ( 687) -REQYRQVKAHVQ-KEDGRVQAFGWSL---PQKYKQ-VTNGQGENKMKNLPVPVYLRPLD 5 ( -) ............................................................ // 0 ( 1001) HPDARLGFEQAF--DEAKRKLASSKSCL-DPE-FLKAIPIMKTRSGMQFSCAAPTLNSCP 1 ( 693) AQDWCLALQRLM--RVKEEEIHSANKCR-LRL-LLPGKP---DKSGRPISFMVVFIT--P 2 ( 821) AHDWTSGLQRLI--LKKEDEIRAADCC----R-IQLQLPGKQDKSGRPTFFTA-VFNTFT 3 ( 732) EDDAGNGVKPA----PGRDPLTCDREGDGEPK-SAHTSPEKKKAKEL------PEMDAT- 4 ( 741) EKDTSMKLWCAVGVNLSGGKTRDGGSVV-GASVFYKDVAGLDTEGSKQRSASQSSLDKLD 5 ( -) ............................................................ // 0 ( 1057) EPSPE--------------V-WVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGA 1 ( 744) NPLSK--------------ISWV--NRLHLAKI---GLREENQ----------------- 2 ( 873) PAIKE--------------S-WV-NSL----QMAKLALEEENHMGW---------FCVED 3 ( 780) --SSR--------------V-WILTSTLTTSKVVIIDANQPGTVVDQFTVCNAHVLCISS 4 ( 800) QELKEQQKELKNQEELSSLV-WICTSTHSATKVLIIDAVQPGNILDSFTVCNSHVLCIAS 5 ( -) ............................................................ // 0 ( 1102) VPGLQPRCHREPPPSLRSPPETAPEPAG--PELDVEAAADEEAATLAEPGPQPCLHISIA 1 ( 768) -PGWL--CPDEDKKS--KAPFWCPILACCIPAFSSRALSLQLGALVHSPVNCPLLGFSAV 2 ( 904) -DGNHIKKEKHPLLVGHMPVMVAKQQ-----EFKIECAAYN---------PEPYLNNESQ 3 ( 823) IPAASDSDY--PPGEMFLDSDVNPEDPG--ADGVLAGITLVGCATRCNVPRSNC---SSR 4 ( 859) VPGA-----RE-----------TDYPAG--EDLSESGQVDKASLCGSMTSNSSAETDSLL 5 ( -) ............................................................ // 0 ( 1160) GSGLEMTPG-LGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSS 1 ( 823) STSL------------------------------PQGYLWVGGGQEGAG---GQVEIFSL 2 ( 949) PDSFSTAHGFLWIGSCTHQMGQIAIVSFQNSTPK-------------VIECFNVE---SR 3 ( 876) GD----TPV-LDKGQGEVATI-----ANGKVNPSQS---TEEATEATEVPDPGPSE-PET 4 ( 901) G-GITVVGC-SAEGVTGAATSP----STNGASPVMDKPPEMEAENSEV-----DENVPTA 5 ( -) ............................................................ // 0 ( 1219) KEATAETTSSEEEQEPGF-LPLSGSFGPG---GPCGTS-PMDGRALRRSSHGSFTRGSLE 1 ( 850) NRPSPRTVKSFPLAAP----VLCMEYIP-----------ELEEEAESRD----------E 2 ( 993) ILCMLYVPVEEKRREPG---------APP---DP--ET-P----AVRAS----------- 3 ( 922) ATLRPGPLTEHVFTDPAP-TPSSGP-QPG---SENGPE-P----------DSSSTRPEPE 4 ( 950) EEATEATEGNAGSAEDTVDISQTGVYTEHVFTDPLGVQIPEDLSPVYQSSNDS---DAYK 5 ( -) ............................................................ // 0 ( 1274) DLLSVDP--------EA-YQSS-----VWLGTEDGCVHVYQSSDSIRDRRNSMKLQH--- 1 ( 885) SPTVADP--------SATVHPT-----ICLGLQDGSILLYSSVDTGTQCLVSCRSPG--- 2 ( 1023) DV----P--------------T-----ICVGTEEGSISIYKSSQGSK----KVRLQHFFT 3 ( 966) P--SGDP--------TG-AGSSAAPT-MWLGAQNGWLYVHSAVANWKKCLHSIKLKD--- 4 ( 1007) DQISVLPNEQDLVREEA-QKMSSLLPTMWLGAQNGCLYVHSSVAQWRKCLHSIKLKD--- 5 ( -) ............................................................ // 0 ( 1317) --AASVTCILYLNNQVFVSLANGELVVYQREAGH-FWDPQNFKSVTLGTQGSPITKMVSV 1 ( 929) --LQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLES-PPVCLTVGPGPVRTLLSL 2 ( 1056) PEKSTVMSLACTSQSLYAGLVNGAVASYARAPDG-SWDSEPQKVIKLGVL--PVRSLLMM 3 ( 1011) ----SVLSLVHVKGRVLVALADGTLAIFHRGEDG-QWDLSNYHLMDLGHPHHSIRCMAVV 4 ( 1063) ----SILSIVHVKGIVLVALADGTLAIFHRGVDG-QWDLSNYHLLDLGRPHHSIRCMTVV 5 ( -) ............................................................ // 0 ( 1374) GGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYH 1 ( 986) EDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGTSIRLFH 2 ( 1113) EDTLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGVGIWIAFTSGSTLRLFH 3 ( 1066) YDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYH 4 ( 1118) HDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRKESQVRQLAWVGDGVWVSIRLDSTLRLYH 5 ( -) ............................................................ // 0 ( 1434) PDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMP 1 ( 1046) TETLEHLQEINIATRTTFLLPG-------QKHLC--VTSLLICQGLLWVGTDQGVIVLLP 2 ( 1173) TETLKHLQDINIATPVHNMLPG-------HQR--LSVTSLLVCHGLLMVGTSLGVLVALP 3 ( 1126) AHTHQHLQDVDIEPYVSKML-GTGKL----GFSFVRITALLVAGSRLWVGTGNGVVISIP 4 ( 1178) AHTYQHLQDVDIEPYVSKML-GTGKL----GFSFVRITALMVSCNRLWVGTGNGVIISIP 5 ( -) ............................................................ // 0 ( 1494) TS------------P----------GTVS----------------CPRAPLSPTGLG--- 1 ( 1097) V-------------P----------RLEG----------------IPKI----TGKG--- 2 ( 1224) V-------------P----------RLQG----------------IPKV----TGRGMVS 3 ( 1181) LT------------ETVVLHRGQLLGLRA----------------NKTSPTSGEGAR--- 4 ( 1233) LTETNKTSGVPGNRP----------GSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCF-- 5 ( -) ............................................................ // 0 ( 1513) -Q----GHTGHVR-----------F-----LA---AVQL-----PD----------GFNL 1 ( 1111) -MVSLNGHCGPVA-----------F-----LAVATSILA-----PDILRSDQEEAEGPRA 2 ( 1241) YH----AHNSPVK-----------F-----IVLATALHE-----KDKDK-------SRDS 3 ( 1210) -P----GGIIHVYGDDSSDRAASSFIPYCSMA---QAQLCFHGHRD----------AVKF 4 ( 1281) -H----GHRDAVK-----------F-----FV---AV-------PG------------QV 5 ( -) ............................................................ // 0 ( 1534) LCP-TPP-----PPPD-T--GPE-----------KLPSLEHR--DSPW--HRGPAPA--- 1 ( 1149) EED-KPDGQAHEPMPD-SHVGRELTRKKGILLQYRLRSTAHL--PGPLLSMREPAPADGA 2 ( 1269) LAP-GPE-----PQDE-D--QKD-----------ALPS-GGA--GSSL--SQGD-PD--- 3 ( 1252) FVS-VP--------------G-N-----------VLATLNGSVLDSP---AEGPGPA--- 4 ( 1298) ISPQSSS-----SGTDLT--GDK-----------AGPSAQE-----PG--SQTPLKS--- 5 ( -) ............................................................ // 0 ( 1567) ------------------------RP-----------KMLVISGGDGYEDFRLSSGGGSS 1 ( 1205) ALEHSEEDGSIYEMADDPDVWVRSRPCARDAHRKEICSVAIISGGQGYRNFGSALGSSGR 2 ( 1300) ------------------------AA-----------IWLGDSLGSMTQKSDLSSSSGSL 3 ( 1279) ------------------------APASEVEGQKLR-NVLVLSGGEGYIDFRIGDGEDDE 4 ( 1330) --------------------------------------MLVISGGEGYIDFRMGDEGGES 5 ( -) ............................................................ // 0 ( 1592) SETVGRD---------DST----------NHLLLWRV 1 ( 1265) QAPCGET---------DST------------LLIWQV 2 ( 1325) SLSHG-S---------SSL----------EHRSEDS. 3 ( 1314) TEEGAGD---------MSQVKPVLSKAERSHIIVWQV 4 ( 1352) -ELLGEDLPLEPSVTKAER----------SHLIVWQV 5 ( -) ..................................... //