# 0 KIAA0380, 1539 aa # 1 KIAA0382 (1443 aa) # 2 KIAA0651 (1114 aa) # 3 KIAA0521 (1050 aa) # 4 KIAA1256 (1676 aa) # 5 KIAA0720 (1091 aa) // exp sw-scr id% from to 1 7.5e-44 2115 32.5 1 1432 2 4.4e-11 672 24.9 235 1098 3 1.8e-10 648 26.8 11 670 4 2.1e-07 412 26.9 1164 1521 5 2.3e-07 462 24.1 235 1063 // 0 ( 1) SRHQSYRILEPWRHRETMSVRLPQSIDRLSSLSSLGDSAPERKSPSHHRQPSDASETTGL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) VQRCVIIQKDQHGFGFTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHL 1 ( 1) .................................AAMRAGVQTGDRIIKVNGTLVTHSNHL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 121) EVVKLIKSGAYVALTLLGSSPSSMGISGLQQDPSPAGAPRITSVIPSPPPPPPLPPPQRI 1 ( 28) EVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERI 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 181) TGPKPLQDPE--VQKHATQILRNMLRQEEKELQDILPLYGDT-SQR----PSEGRLSLD- 1 ( 88) TSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 233) -----SQEGDSGLDSG--TERFP-----SLSESLMNRNSVL-------------SDPGLD 1 ( 148) LQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNAD 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 268) SPRTSPVIMARVAQHHRRQGSDAAVPSTGDQGVDQSPK----PLIIGPEEDYDPGYFNNE 1 ( 208) SPKSGP--KERIYLEENPEKSET-IQDTDTQSLVGSPSTRIAPHIIGAEDD-DFGTEHEQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 324) SD---IIFQDLEKLKSRPAHLGVFLRYIFSQADPSPLLFYLCAEVYQQASPKDSRSLGKD 1 ( 264) INGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 381) IWNIFLEKNAPLRVKIPEMLQAEIDSRLRN--SEDA-RGVLCEAQEAAMPEIQEQIHDYR 1 ( 324) FHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFR 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 438) TKRTLGLGSLYGENDLLDLDGDPLR-----ERQVAEKQLAALGDIL---SKYEEDRSAPM 1 ( 384) QKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTM 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 490) DFALNTYMSHAGIRLREARPSNTAEKAQSAPDKDKWLPFFPKTKKSSNSKKEKDALEDKK 1 ( 444) QYVILMYMKHLGVKVKE--PRNLEHK------RGR-IGFLPKIKQSM--KKDKEGEEKGK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 550) RNPILKYIGKPKSSSQSTFHIPLSPVEVKPGNVRNIIQHFENNQQYDAP--------EP- 1 ( 493) RRGFPSILGPPRRPSRHDNSAIGRAMELQ--KARHP-KHLSTPSSV-SP--------EPQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 235) ............................KPGDEGKVEQGMKDSKSLSLPILRPAGTGPP- // 0 ( 601) GTQRLSTGSFPE--DLLESD----SSRSEIR--LGRSESLKGREEMKRSRKAENVPRSRS 1 ( 541) DSAKLRQSGLAN--EGTDAGYLPANSMSSVA--SGASFSQEGGKE--------------N 2 ( 235) ...................................QSVSLRSKTTIRERPSSAIYP---S 3 ( 11) ...RASLKEHPR--GTLLSD----GSPALSRN-VGMTVSQKGGPQPTPSPAGPGTQLGPI 4 ( -) ............................................................ 5 ( 266) ALERVDAQSRRESLDILAPG----RRRKNMSEFLGEA-SIPGQEPPTPSSCSLPSGSSGS // 0 ( 653) DVDMDAAAE--A-TRLHQSASSSTSSLSTRSLENP--TPPF---------TPKMGRRSIE 1 ( 583) DTGSKQVGE--T-SAPGDTLDGTPRTLNT-VFDFP--PPPLDQVQEEECEVERVTEHGTP 2 ( 257) D-SFRQSLL--G-SRRGRSSLSLAKSVSTTNIAGH--FNDE---------SP-LGLRRIL 3 ( 61) TGEMDEADS--AFLKFKQTADDSLS-LTSPNTESIFVEDPY---------TASL-RSEIE 4 ( -) ............................................................ 5 ( 321) TNSGDSWKNRAA-SRFSGFFSSGPSTSAFGREVDK--MEQL---------EGKLHTYSLF // 0 ( 699) S-PS---LG----FCTDTL-LPHLLEDDLGQ---LSDLE-PEPD--AQNWQHTVGKDVVA 1 ( 637) K-PF---RK----FDSVAF-GESQSEDEQFE----NDLE-TDPP----NWQQLVSREVLL 2 ( 301) S-QSTDSLN----MRNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQ 3 ( 108) S-DG------------------HEFE--------------------AESWSLAVDA-AYA 4 ( 1164) ...................................TDSD-P-----SQQW--CADLQTLD 5 ( 369) GLPR---LPRGLRFDHDSW-EEEYDEDEDED---NACLR-LE-----DSWRELI--DGHE // 0 ( 744) GLTQREI-DRQEVINELFVTEASHLRTLRVLDLIFY---QRMKKENLMPREELARLFPNL 1 ( 679) GLKPCEI-KRQEVINELFYTERAHVRTLKVLDQVFY---QRVSREGILSPSELRKIFSNL 2 ( 356) QHKKEVM-KQQDVIYELIQTELHHVRTLKIMTRLFR---TGMLEELHLEPGVVQGLFPCV 3 ( 128) KKQKREVVKRQDVLYELMQTEVHHVRTLKIMLKVYS---RALQEELQFSSKAIGRLFPCA 4 ( 1181) TMQPIER-KRQGYIHELIQTEERYMADLQLVVEVFQ---KRMAESGFLTEGEMALIFVNW 5 ( 414) KLTRRQC-HQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNI // 0 ( 800) PELIEIHNS-WCEAM----KKLR----E--EG----P------IIKEISDLMLARFDGPA 1 ( 735) EDILQLHIG-LNEQM----KAVR----KRNET----S------VIDQIGEDLLTWFSGPG 2 ( 412) DELSDIHTR-FLSQL----LERR----R--QALC--PGSTRNFVIHRLGDLLISQFSGPS 3 ( 185) DDLLETHSH-FLARL----KERRQESLE--EG----SDRNY--VIQKIGDLLVQQFSGEN 4 ( 1237) KELIMSNTK-LLKAL----RVRK----K--TGGEKMP------V-QMIGDILAAELSH-- 5 ( 473) PEIAQLHRRLWASVMAPVLEKAR----R--TR----A------LLQPGDFLKGFKMFGS- // 0 ( 839) REELQQVAAQFCSYQSIALELIKTKQRKESRFQLFMQEAESHPQCRRLQLRDLIISEMQR 1 ( 776) EEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQR 2 ( 459) AEQMCKTYSEFCSRHSKALKLYKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVTQR 3 ( 232) GERMKEKYGVFCSGHNEAVSHYKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQR 4 ( 1277) ----MQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQR 5 ( 516) ---LFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQR // 0 ( 899) LTKYPLLLESIIKHTEGGTSEHEKLCRARDQCREILKYVNEAVKQTENRHRLEGYQKRLD 1 ( 836) LTKYPLLLDNIAKYTEWPT-EREKVKKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLD 2 ( 519) ITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMD 3 ( 292) ITKYPVLVERIIQNTEAGTEDYEDLTQALNLIKDIISQVDAKVSECEKGQRLREIAGKMD 4 ( 1333) ITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQ 5 ( 573) LTKYPLLLKSVLRKTEEPRAK-EAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRID // 0 ( 959) ATALERAS----NPLAAE--FKSLD--LT----------TRKMIHEGPLTWRISKDKTLD 1 ( 895) TSSLKLSE----YPNVEE--LRNLD--LT----------KRKMIHEGPLVWKVNRDKTID 2 ( 579) P----RAQ----TPVPGKGPFGREE--LL----------RRKLIHDGCLLWKTATGRFKD 3 ( 352) LKSSSKLK----NGLT----FRKED--ML----------QRQLHLEGMLCWKTTSGRLKD 4 ( 1393) CEGL---A----EQLI----FNSLTNCLG----------PRKLLHSGKL-YKTKSNK--E 5 ( 632) AYEVVESSSDEVDKLLKE--FLHLD--LTAPIPGASPEETRQLLLEGSLRMKEGKDSKMD // 0 ( 1001) LHVLLLEDLLVLLQKQDEKLLLKCHSKTAVGSSDSKQTF----SPVLKLNAVLIR---SV 1 ( 937) LYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTF----SPVIKLSTVLVR---QV 2 ( 619) VLVLLMTDVLVFLQEKDQKYIFPTLDKPSV----------------VSLQNLIVR---DI 3 ( 392) ILAILLTDVLLLLQEKDQKYVF--------ASVDSK-------PPVISLQKLIVR---EV 4 ( 1429) LHGFLFNDFL-LLTYMVKQFAVSSGSEK-LFSSKSNAQFKMYKTPIF-LNEVLVKLPTDP 5 ( 688) VYCFLFTDLLLVTK--------------AVKKAERTRVI----RPPLLVDKIVCR---EL // 0 ( 1054) ATDKRAFFIICTSKLGPP-QIYELVALTSSDKNTWMELLEEAVRNATRHPGAAPMPVHPP 1 ( 990) ATDNKALFVISMSDNGA--QIYELVAQTVSEKTVWQDLICR-MAASVKEQSTKPIPLPQS 2 ( 660) ANQEKGMFLISAA---PP-EMYEVHTASRDDRSTWIRVIQQSVRTC---PSREDFPLIET 3 ( 434) ANEEKAMFLISASLQGP--EMYEIYTSSKEDRNAWMAHIQRAVESC---PDEEEGPFSLP 4 ( 1486) SSDEPVFHI---SHI--D-RVYTLRTDNINERTAWVQKIKAA.................. 5 ( 727) -RDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNA-QNQLQQLRA------QE // 0 ( 1113) PPGP--REPAQQGPTPSR--VEL--DDSDVF----HGEPEPE--------ELPGGTGSQQ 1 ( 1047) TPGE--GDNDEEDPSKLK--EEQ--HGISVT-----GLQSPD--------RDLGLESTL- 2 ( 713) EDEAYLRRIKMELQQKDRALVELLREKVGLFAEMTHFQAEEDGGSGMALPTLPRGLFRSE 3 ( 489) -------EEERKVVEARA--TRL--RD---F----Q---ERL--------SMKDQLIAQS 4 ( -) ............................................................ 5 ( 779) PPGS--QQPLQS--------LEE--EEDEQE----EEEEEEE--------EEEEGEDSGT // 0 ( 1155) RVQG-KHQVLLED---P--EQE-----GSAEEE-----ELGVL-P---C----------- 1 ( 1087) -ISS-KPQS--HS---L--STS-----GKSEVR-----DLFVA-ERQFA----------- 2 ( 773) SLESPRGERLLQD---AIREVE-----GLKDLLVGPGVELLLT-PR--E----------- 3 ( 520) LLE--KQQIYLEM---A--EM------GGLED----------L-P---Q----------- 4 ( -) ............................................................ 5 ( 815) SAAS-SPTIMRKSSGSP--DSQHCASDGSTETL-----AMVVVEP---GDTLSSPEFDSG // 0 ( 1184) PSTSLDGE---NRGI-R----TRNPIHLAFP-G---PLFM-EGLADSALEDV-------- 1 ( 1116) KEQHTDGT---LKEV-G------EDYQIAIP-DSHLPVSE-ERWALDALRNL-------- 2 ( 811) PALPLEPD---SGGN-TSPGVTANGEARTFN-G---SIELCRADSDSSQRDRNGNQLRSP 3 ( 542) P-----------RGLFR----GGDPSE-TLQ-G---ELIL-K----SAMSEI-------- 4 ( -) ............................................................ 5 ( 864) PFSSQSDETSLSTTA-S----SATPTSELLPLG---P--V-DGRSCSMDSAY-------- // 0 ( 1223) --ENLRHLI-LWSL--LPGHTMETQAAQEP---ED--------DLTPTP----S------ 1 ( 1156) --GLLKQLL-VQQL------GLTEKSVQE--------------DWQHFP----R------ 2 ( 863) QEEALQRLVNLYGL--L--HGLQAAVAQQDTLMEA--------RFPEGPERREK------ 3 ( 569) --EGIQSLI-CRRLGSANGQAEDGGSSTGP---PRRAETFAGYDCTNSP----TKNGSFK 4 ( -) ............................................................ 5 ( 905) --GTLSPTS-LQDF--VAPGPMAELVPRAP---ES--------PRVPSP----P------ // 0 ( 1257) --VISVTSHPWDPGSPGQAPPG-----GEGDNTQL---AGLEGE--RPE-Q-EDMGLCSL 1 ( 1183) --YRTASQGP----QTDSVIQN-----SENIKAYH---SG-EGH--MPF-R-TGTGDIAT 2 ( 905) --LCRANSRDGEAGRAGAAPVA-----PEKQATEL---ALLQRQ--HALLQ-EELRRCR- 3 ( 619) KKVSSTDPRPRDWRGPPNSPDL-----KLSD-SDI---PGSSEE--SPQ-VVEAPGTESD 4 ( -) ............................................................ 5 ( 939) --P-SPRLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPS-R-SLSELCLA // 0 ( 1303) EHLPP-RTRNSGIWESPELDRNLA-EDASSTEAAGGYKVVRKAEVAGS--KVVPALPESG 1 ( 1224) CY-SP-RTSTESF--APRDSVGLAPQDSQASNILVMDHMIMTPEMPTM--EPEGGLDDSG 2 ( 951) ------RLGEERATEAGSLEARLR-E----SEQARAL-LEREAEEA-R--RQLAAL---G 3 ( 667) PRLP........................................................ 4 ( -) ............................................................ 5 ( 994) VPAPGIRTQGSPQEAGPSWD---C-RGAPSPGSGPGLVGCLAGEPAGSHRKRCGDLP-SG // 0 ( 1359) Q---------SEPGPPEVEGGT---------KAT---------GNCFYVSMPSGPP--DS 1 ( 1278) EHFFDAREAHSDENPSEGDGAVNKEEKDVNLRIS---------GN--YLILDGYDPVQES 2 ( 993) Q---------TEPLPAEAPWAR---------RPVDPRRRSLPAGDALYLSFNPPQP--SR 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 1049) A---------SPRVQPEPPPGV---------SA........................... // 0 ( 1390) STDHSEA------PMSP-PQPDSLPAGQTEPQPQLQGGNDDPRRPS-------------- 1 ( 1327) STDEEVASSLTLQPMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSC 2 ( 1033) GTDRLDL------PVTT-RSVHR----NFEDRERQELGSPEERLQD-------------- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1429) ---RSPPSLALRDVGMIFHTIEQLTLKLNRLKDMELAHRELLKSLGGESSGGTTPVGSFH 1 ( 1387) FEIQSPSSCA-DSQSQIMEYIHKIEADLEHLKKVEESYTILCQRLAG............. 2 ( 1068) ---SSDPDTGSEEEGSSRLSPPHSPRDFTRMQDI.......................... 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1486) TEAARWTDGSLSPPAKEPLASDSRNSHELGPCPEDGSDAPLEDSTADAAASPGP 1 ( -) ...................................................... 2 ( -) ...................................................... 3 ( -) ...................................................... 4 ( -) ...................................................... 5 ( -) ...................................................... //