# 0 KIAA0422, 1160 aa # 1 KIAA0511 (933 aa) # 2 KIAA1060 (887 aa) # 3 KIAA0037 (1088 aa) # 4 KIAA0520 (1364 aa) // exp sw-scr id% from to 1 7.7e-46 2014 40.4 11 914 2 2.7e-37 2154 42.4 9 873 3 5.3e-37 2181 39.1 7 1075 4 5.3e-28 1300 28.9 64 1259 // 0 ( 1) GRRTAGGTARTRGLGGPRDGRPAGRSPRGRRGGGPGQARSRAGSNMSWFSGLLVPKVDER 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 61) KTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGPPRCPWQDDAFIRRGG 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 121) PGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGR-SCWRRLVQ--VFQ----- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 7) ............................................WRMPAKGRYFL----- 4 ( 64) .....................SCSSSGDSGGVPRRVGGGGRLRRQKKLPQ--LFERASSR // 0 ( 173) --SKQFRSAKLERLYQRYFFQMNQSSLT---L---LMAVLVLLTAVLLAF-HAAP---AR 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 18) --NEGEEGPDQDALYEKYQLTSQHGPLL---LTLLLVAATACVALIIIAFSQGDP---SR 4 ( 101) WWDPKFDSVNLEEACLERCFPQTQRRFRYALF---YIGFACLLWSIYFAV-HMRSRLIVM // 0 ( 221) PQPAY-VALLACA--AALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQ------VGG 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 70) HQAILGMAFLVLAVFAALSVLMYVEC---LLRR---WLRALALLTWACLVA------LGY 4 ( 157) VAPAL-CFLLVCV--GFFLFTFTKLYARH-YAWTSL-ALTLLVFALTLAAQFQVLTPVSG // 0 ( 272) -----ALAADPRSPSAGL-------WCPV----FFVYIAYTLLPIRMRAAVLSGLGLSTL 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 118) -----VLVFDAWTKAACA-------WEQVPFFLFIVFVVYTLLPFSMRGAVAVGAVSTAS 4 ( 212) RGDSSNLTATARPTDTCLSQVGSFSMC-I----EVLFLLYTVMHLPLYLSLCLGVAYSVL // 0 ( 316) HLILAWQLNR--------G----DAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAF 1 ( 11) ..........................LLREILANVFLYLCAIAVGIMSYYMADRKHRKAF 2 ( 9) ....................................................ELALQQTY 3 ( 166) HLLVLGSLMG--------GFTTPSVRVGLQLLANAVIFLCGNLTGAFHKHQMQDASRDLF 4 ( 267) FETFGYHFRDEACFPSPGA----GALHWELLSRG-LLHGCIHAIGVHLFVMSQVRSRSTF // 0 ( 364) QETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEM-----------------------K 1 ( 45) LEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEM-----------------------L 2 ( 17) QDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEM-----------------------K 3 ( 218) TYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGM-----------------------K 4 ( 322) LKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRK // 0 ( 401) EDIN---TK----KE--------DMM-----FHKIYIQKHDNVSILFADIEGFTSLASQC 1 ( 82) KDMKKDESQ----KD--------QQQ-----FNTMYMYRHENVSILFADIVGFTQLSSAC 2 ( 54) AEII---QRLQGPKA--------GQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDC 3 ( 255) LAII---ERL---KEHGDRRCMPDNN-----FHSLYVKRHQNVSILYADIVGFTQLASDC 4 ( 382) KKSS---IQ----KA--------PIA-----FRPFKMQQIEEVSILFADIVGFTKMSANK // 0 ( 441) TAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMI 1 ( 125) SAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMV 2 ( 103) SPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMC 3 ( 304) SPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDMC 4 ( 422) SAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMI // 0 ( 501) EAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIH 1 ( 185) EAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVH 2 ( 163) EAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVH 3 ( 364) QAIKQVREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVH 4 ( 482) KAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVH // 0 ( 561) ITRATLQYLNGDYEVEPGRGGER--NAYLKEQ--HIETFLILG--------A-SQKRKEE 1 ( 245) ISQSTMDCLKGEFDVEPGDGGSR--CDYLEEK--GIETYLIIASKPEVKKTA-TQNGLNG 2 ( 223) ISSVTLEHLNGAYKVEEGDGDIR--DPYLKQH--LVKTYFVIN--------P-KGERRSP 3 ( 424) ITEATLKHLDKAYEVEDGHGQQR--DPYLKEM--NIRTYLVID--------PRSQQPPPP 4 ( 542) ISEATAKYLDDRYEMEDGKVIERLGQSVVADQLKGLKTYLISG-----------QRAKES // 0 ( 608) KAMLAKLQ-----RTRAN-SMEGLM----PRW--------VPD-----RAFSR--T--KD 1 ( 300) SALPNGAP-----ASSKS-SSPALI----ETK--------EPNG----SAHSSGST--SE 2 ( 270) QHLFRPRHTLDGAKMRASVRMTRYL----ESW--------GAA-----KPFAH--LHHRD 3 ( 472) SQHLPRPKGDAALKMRASVRMTRYL----ESW--------GAA-----RPFAH--LNHRE 4 ( 591) RCSCAEAL-----LSGFE-VIDGSQVSSGPRGQGTASSGNVSDLAQTVKTFDN--L--KT // 0 ( 641) SKA----FR------------Q---------MGIDD-SSKD--------NRGTQ------ 1 ( 336) KPE----EQ------------D---------AQADN-PSFP--------NPRRRLRLQDL 2 ( 311) SMT----TE------------NGKISTTDVPMGQHNFQNRT--------LRTKS------ 3 ( 513) SVS----SG------------E---------THVPN-GRRPKSVPQR--HRRTP------ 4 ( 641) CPSCGITFAPKSEAGAEGGAPQ---------NGCQD-EHKNSTKASGGPNPKTQ------ // 0 ( 661) -----D-AL--NP-----EDE-----------------------VDE-------F--LSR 1 ( 362) ADRVVD-AS--ED-----EHE-----------------------LNQ-------L--LNE 2 ( 341) -----Q-KK--RF-----EEE-----------------------LNE-------R--MIQ 3 ( 539) -----DRSM--SPKGRSEDDS-----------------------YDD-------E--MLS 4 ( 685) -----N-GLLSPP-----QEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIRE // 0 ( 676) AIDARSIDQ---LRKDH----------VRRFLLT--FQREDLEKKYSRK----------- 1 ( 382) ALLERESAQ---VVKKR-----------NTFLLSMRFMDPEMETRYSVE----------- 2 ( 356) AIDGINAQKQW-LKSED----------IQRISLL--FYNKVLEKEYRAT----------- 3 ( 560) AIEGLSSTRPCCSKSDD----------FYTFGSI--FLEKGFEREYRLA----------- 4 ( 734) KTDAHFVDV---IKEDSLMKDYFFKPPINQFSLN--FLDQELERSYRTSYQEEVIKNSPV // 0 ( 710) ---VDPRFGAYVACALLVFCFI-----CFIQL--LIFP-----HSTLM---LGI-YASIF 1 ( 417) ---KEKQSGAAFSCSCVVLLCT-----ALVEI--LIDPWLMTNYVTFM---VG----EIL 2 ( 392) ---ALPAFKYYVTCACLIFFCI-----FIVQI--LVLP-----KTSV----LGISFGAAF 3 ( 597) ---PIPRARHDFACASLIFVCI-----LLVHV--LLMP-----RTAALGVSFGL-VACVL 4 ( 789) KTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVP-----PPPAA---LAV-FSAAL // 0 ( 751) LLLLITVLIC---A--------VYSC----GS-LFP-------KALQRLSRS--IVRSR- 1 ( 460) LLILTICSLA---A--------IFP------R-AFP-------KKLVAFSTW--IDRTRW 2 ( 433) LLLAFILFVCFAGQ--------LLQC----SK-KAS-------PLLMWLLKSSGIIANR- 3 ( 641) GLVLGLCFAT---K--------FSRCCPARGT-LCTISERVETQPLLRLTLA--VLTIG- 4 ( 840) LLEVLSLAVS---IRMVFFLEDVMAC----TKRLLE-------WIAGWLPRH--CIGAI- // 0 ( 785) A-HST-------------A----------------VGIFS-VLLVFT---SAIANM---- 1 ( 493) A-RNTWAMLAIFILVMANV----------------VDMLS-CLQYYTGPSNATAGM---- 2 ( 472) PWPRI-------------S----------------LTIIT-TAIILM---MAVFNM---- 3 ( 686) S-LLT-------------VAIINLPLMPFQVPELPVGNET-GLLAAS---SKTRALCEPL 4 ( 883) L-VSLP------------A----------------LAVYSHVTSEYE---TNIHFP---- // 0 ( 807) -YFIGNM-L-----------LSLLASSVFLHIS---SIGKLA-MIFVLGLIYL------- 1 ( 531) -ETEGSC-LENPKYYNYVAVLSLIATIMLVQVS---HMVKLTLMLLVAGAVAT------- 2 ( 495) -FFLSDS-E-----------ETIPPTANTTNTSFSASNNQVA-ILRAQNLFFLPYFIYSC 3 ( 728) PYYTCSC-V-----------LGFIACSVFLRMS---LEPKVV-LLTVALVAYL------- 4 ( 907) -VFTGSAAL-----------IAVVHYCNFCQLS---SWMRSS-LATVVGAGPL------- // 0 ( 843) VLLL--LGPPATIFDNYDL---------------LLGVHGLASSNETFDGLD-CPAAGRV 1 ( 579) INLY--AWRP--VFDEYDHKRFREHDLP------MVALEQMQGFNPGLNGTDRLPL---V 2 ( 541) ILGL--ISCSVFLRVNYELKMLIMMVALVGYNTILLHTHAHVLGDYSQVLFE-RPGIWK- 3 ( 765) VLFN--LSP-CWQWDCCGQ---------------GLG--NLTKPNGTTSGT---PSCSWK 4 ( 944) LLLYVSLCPDSSVLTSP-----------------LDAVQNFSSERNPCNS-S-VPRDLRR // 0 ( 885) ALKYMTPVILLVFALALYL---HAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLH 1 ( 626) PSKYSMTVMVFLMMLSFYY---FSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVT 2 ( 597) DLKTMGSVSLSIFFITLLV---LGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLE 3 ( 802) DLKTMTNFYLVLFYITLLT---LSRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLE 4 ( 985) PASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLR // 0 ( 942) NILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEG-VECLRLL 1 ( 683) NMLPEHVARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGG-IECLRFL 2 ( 654) NVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEG-LECLRLL 3 ( 859) NVLPAHVAAHFIG-DKLNEDWYHQSYDCVCVMFASVPDFKVFYTECDVNKEG-LECLRLL 4 ( 1045) NIIPYHVAEQL-----KVSQTYSKNHDSGGVIFASIVNFSEFY---EENYEGGKECYRVL // 0 ( 1001) NEIIADFDEIISEERFRQLEKIKTIGSTYMAASGL----N-A------STY------D-- 1 ( 742) NEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVN-T------NGFASSNKED-- 2 ( 713) NEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGL----S-AVPSQEHSQE------P-- 3 ( 917) NEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGL----SVA------SGH------ENQ 4 ( 1097) NELIGDFDELLSKPDYSSIEKIKTIGATYMAASGL----N--------TAQ------A-- // 0 ( 1042) QVG---R---SHITALADYAMRLMEQMKHINEHSFN-NFQMKIGLNMGPVVAGVIGARKP 1 ( 793) KSE---RERWQHLADLADFALAMKDTLTNINNQSFN-NFMLRIGMNKGGVLAGVIGARKP 2 ( 760) ERQ---Y---MHIGTMVEFAFALVGKLDAINKHSFN-DFKLRVGINHGPVIAGVIGAQKP 3 ( 961) ELE---RQH-AHIGVMVEFSIALMSKLDGINRHSFN-SFRLRVGINHGPVIAGVIGARKP 4 ( 1137) QDGSHPQ---EHLQILFEFAKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKL // 0 ( 1095) QYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFL 1 ( 849) HYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFL 2 ( 813) QYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFV 3 ( 1016) QYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKGELRTYFV 4 ( 1194) LYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLY // 0 ( 1155) NGGPSS 1 ( 909) KGRDKL 2 ( 873) N..... 3 ( -) ...... 4 ( 1254) PKCTDH //