# 0 KIAA1498, 1731 aa # 1 KIAA0309 (3053 aa) # 2 KIAA1259 (1561 aa) # 3 KIAA1122 (1048 aa) # 4 KIAA1564 (2432 aa) # 5 KIAA0308 (2759 aa) // exp sw-scr id% from to 1 6e-33 2126 35.0 10 1192 2 1.6e-08 766 27.3 270 836 3 9.4e-07 602 26.8 288 809 4 4.1e-06 599 23.9 91 952 5 0.00061 487 30.3 737 1028 // 0 ( 1) IMHHGTGPQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) QLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 121) YIQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 181) ISLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGP 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 241) QSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPG 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 301) VLLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASP 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 361) EMAQMRKQCLDYHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLR 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 421) QNDLDIEEEEEEEEEEEEKSEVINDEQQALAGSLVAGAGSTVETDLFKRQQAMPSTGMAE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 481) QSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 91) QPSRPVKQLVLQPVKGSAPAGNPGATGPPLKPAVT--LTSTP--TQGESKRITLVLQQPQ 5 ( -) ............................................................ // 0 ( 541) TGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQP-QVVEAQTQLQIPVKTQQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 147) SGGP---QGHRHVVLGSLPGKIVLQGNQLAALTQAKNAQGQPAKVVTIQLQVQQP---QQ 5 ( -) ............................................................ // 0 ( 600) PNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 201) KIQIVPQPPSSQ-P----QPQQ-----------------------------------PPS 5 ( -) ............................................................ // 0 ( 660) PRPLPTSSTSSLAPVSGSGPGPSP---ARSSPVN---RPSSATNKALSPVTSRTPGVVAS 1 ( 10) ....PVSPASSSSPASSGAGGISPQHIAQDSSLD---GPPGPPDGATVPLEGFS--LSQA 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 221) TQPVTLSSVQQ-AQIMGPGQSPGQ---RLSVPVKVVLQPQAGSSQGASSGLSVVKVLSAS 5 ( -) ............................................................ // 0 ( 714) APTKPQSPAQNATSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPRP 1 ( 61) ADLANKGP------KWEKSHAEIAEQAKHEAEIETRIAELRKEGFWSLKRLPKVPEPPRP 2 ( 270) ...............................................KKHLSIEQLNARR 3 ( -) ............................................................ 4 ( 277) EVAALSSPASSAPHS--GGKTGMEENRRLEHQKKQEKANRIVAEAIARARARGEQNIPRV 5 ( -) ............................................................ // 0 ( 774) KSHWDYLLE-EMQWM-ATDFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKK--EEQS 1 ( 115) KGHWDYLCE-EMQWL-SADFAQERRWKRGVARKVVRMVIRHHEEQRQKEERARR--EEQA 2 ( 283) RKVWLSIVKKELPKA-NKQKASARNLFLTNSRKLAHQCMKEVRRAALQAQKNCK--ETLP 3 ( 288) ...............................KQELREVLKEHEWMYTEALESLKVFAEDQ 4 ( 335) LNE-----D-ELPSVRPEEEGEKKRRKKSAGERLKEEKPKKSKTSGASKTKGKS--KLNT 5 ( -) ............................................................ // 0 ( 830) RLRRIAAS---TAREIECFWSNIEQ-VV-EIKLRVELE--EKRKKALNLQ---------- 1 ( 171) KLRRIAST---MAKDVRQFWSNVEK-VV-QFKQQSRLE--EKRKKALDLHLDFIVGQTEK 2 ( 340) RARRLT-------KEMLLYWKKYEK-VEKEHRKRAEKEALEQRKLDEEMR---------- 3 ( 317) DMQYVSQSEVPNGKEVSSRSQNYPKNAT-KTKLKQKFS--MKAQNGFNKK---------- 4 ( 387) ITPVVGKK---RKRNTSSDNSDVEV-MP-AQSPREDEE--SSIQKRRSNR---------- 5 ( -) ............................................................ // 0 ( -) ------------------------------------------------------------ 1 ( 224) YSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEET 2 ( -) ------------------------------------------------------------ 3 ( -) ------------------------------------------------------------ 4 ( -) ------------------------------------------------------------ 5 ( -) ............................................................ // 0 ( 873) ------------KVSRRG--KEL-RPKGFDALQE--------------------SSLDS- 1 ( 284) IEVEEQQEGNDAEAQRRE--IELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSD 2 ( 382) ------------EAKRQQ--RKL----NF-LITQ--------------------TELYA- 3 ( 364) ---------------RKK--NVF-NPK--RVVED--------------------SEYDS- 4 ( 430) ------------QVKRKKYTEDL-DIKITDDEEE--------------------EEVD-- 5 ( -) ............................................................ // 0 ( 897) ------------------------GMSGRKRKA--------SISLTDDEVDDEEETI--- 1 ( 342) TRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTI--- 2 ( 402) ------------------------HFMSRKR------------DMGHDGIQEEILRK--- 3 ( 383) ------------------------G-----SDV--------GSSL-DEDYSSGEEVM--- 4 ( 455) -------------------------VTGPIKPE--------PI-LPEPVQEPDGETLPSM 5 ( -) ............................................................ // 0 ( 922) -----EEEEANEGVVD-HQTELSNLAKEAELPLLD-------LMKLYEGAFL-PSS---- 1 ( 399) -----AAEEQLEGEVD-HAMELSELAREGELSMEE-------LLQQYAGAYA-PGSGSSE 2 ( 423) -----LEDSSTQRQIDIGGGVVVNITQED----YD--------SNHFKAQAL-KNA---- 3 ( 402) -----ED--GYKGKIL-HFLQDASIGELTLIPQCS-------QKKAQKITELRPFN---- 4 ( 481) QFFVENPSEEDAAIVD-KVLSMRIVKK--ELPSGQYTEAEEFFVKYKNYSYL--HC---- 5 ( -) ............................................................ // 0 ( 964) ----------------QWP--RPKPDGEDTSGE--------EDADD-------------- 1 ( 445) DEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSAS 2 ( 461) ----------------ENA--YHIHQARTRSFD--------EDA---------------- 3 ( 443) ----------------SWE--ALFTKMSKTNGL--------SE----------------- 4 ( 532) ----------------EWA--TISQLEKDKRIH--------QKLKR-------------- 5 ( -) ............................................................ // 0 ( 984) --------------CPG-----------DRES-RKDLVLIDSLFIMDQFKAAERMNIGKP 1 ( 505) EESESEESEDAQSQSQA-----------DEEE-EDDDFGVEYLLARDEEQSEADAGSGPP 2 ( 479) -----------------------------KES-RAA-----------ALRAANKSGTGFG 3 ( 460) -----------------------------------DLIWHCKTLIQERDVVIRLMN---- 4 ( 552) --------------FKTKMAQMRHFFHEDEEPFNPDYVEVDR--ILDESHSIDKDN-GEP 5 ( -) ............................................................ // 0 ( 1018) NA--------KDIA--------DVTAVAEAILPKGSARVTTSVKFNAPSLLY-------- 1 ( 553) TPGPTTLGPKKEIT--------DIAAAAESLQPKGYTLATTQVKTPIPLLLR-------- 2 ( 498) ES--------YSLA--------NPSIRAGEDIPQ-------------PTIFN-------- 3 ( 481) KC--------EDIS--------NKLTKQVTMLTGNGG----GWNIEQPSILN-------- 4 ( 595) VI--------YYLVKWCSLPYEDSTWELKEDVDEGKIREFKRIQSRHPELKRVNRPQASA 5 ( -) ............................................................ // 0 ( 1054) -------------GAL--RDYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHL 1 ( 597) -------------GQL--REYQHIGLDWLVTMYEKKLNGILADEMGLGKTIQTISLLAHL 2 ( 521) -------------GKL--KGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHL 3 ( 513) -------------QSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYL 4 ( 647) WKKLELSHEYKNRNQL--REYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIAFLQEV 5 ( 737) ...............L--REYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLYEI // 0 ( 1099) ACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILSYIGS--HRELKAKRQEW-AE--- 1 ( 642) ACEKGNWGPHLIIVPTSVMLNWEMELKRWCPSFKILTYYGA--QKERKLKRQGW-TK--- 2 ( 566) AERENIWGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWGN--PHDRKVIRRFW-SQ--- 3 ( 560) Y-QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGS--QEERKQIRFNIHSR--- 4 ( 705) Y-NVGIHGPFLVIAPLSTITNWEREFNTWTE-MNTIVYHGSLASRQMIQQYEMY-CKDSR 5 ( 780) LLT-GIRGPFLIIAPLSTIANWEREFRTWTD-INVVVYHGSLISRQMIQQYEMY-FR--- // 0 ( 1153) ----PN------S---------FHVCITSYTQFFRGL---TAFTRVRWKCLVIDEMQRVK 1 ( 696) ----PN------A---------FHVCITSYKLVLQDH---QAFRRKNWRYLILDEAQNIK 2 ( 620) ----KTLYTQDAP---------FHVVITSYQLVVQDV---KYFQRVKWQYMVLDEAQALK 3 ( 614) ----YE------D---------YNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLK 4 ( 762) GRLIPG------AYK-------FDALITTFEMILSDC---PELREIEWRCVIIDEAHRLK 5 ( 834) ----DS------QGRIIRGAYRFQAIITTFEMILGGC---GELNAIEWRCVIIDEAHRLK // 0 ( 1191) GMTERHWEAVFTLQSQQRLLLIDSPLHNTFLELWTMVHFLVPGIS-------RPYLSSPL 1 ( 734) NFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHVFQSHREF-KEWFSNPL 2 ( 664) SSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEF-NEWFSKDI 3 ( 655) NMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKT 4 ( 806) NRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPS-Q-------FPSESEFL 5 ( 881) NKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEELFSLLHFL-----------------EPL // 0 ( 1244) RAPSEES--QDY----YHKVVIRLHRVTQPFILRRTKRDVEKQLTKKYEHVLKCRLSNRQ 1 ( 793) TGMIEGS--QEY----NEGLVKRLHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQ 2 ( 723) ESHAENK--SAI----DENQLSRLHMILKPFMLRRIKKDVENELSDKIEILMYCQLTSRQ 3 ( 715) KSADEQS--I-Y----EKERIAHAKQIIKPFILRRVKEEVLKQLPPKKDRIELCAMSEKQ 4 ( 858) KDFGDLK--TE-------EQVQKLQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQ 5 ( 924) RFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKKLAPKEETIIEVELTNIQ // 0 ( 1298) KALYEDV--------ILQ-PG---TQEALKSGH--FVNVLSILVRLQRICNHPGLVEPRH 1 ( 847) RCLYDDF--------MAQ-TT---TKETLATGH--FMSVINILMQLRKVCNHPNLFDPRP 2 ( 777) KLLYQALKNKISIEDLLQ-SSMGSTQQAQNTTS----SLMNLVMQFRKVCNHPELFERQE 3 ( 768) EQLYLGL--------FNRLKK---SINNLVTEK--NTEMCNVMMQLRKMANHPLL..... 4 ( 909) KKYYRAI--------LEK-NF---SFLSKGAGHTNMPNLLNTMMELRKCCNHPYLI.... 5 ( 984) KKYYRAI--------LEK-NF---SFLSKGAGQTNVPNLVNTMMELRKCCNHPYLIK... // 0 ( 1344) PGSSYVAGPLEYPSASLILKALERDFWKEADLSMFDLIGLENKITRHEAE-LLSKKKIPR 1 ( 893) VTSPFITPGICFSTASLVLRATDVHPLQRIDMGRFDLIGLEGRVSRYEADTFLPRHRLSR 2 ( 832) TWSPF....................................................... 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1403) KLMEEISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAF-----------PSTHPP 1 ( 953) RVLLEVATAPDPPPRPKPVKMKVNRMLQPVP---KQEGRTVVVVNNPRAPLGPVPVRPPP 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1452) R---TAAPTTA------------SAAPQGPL---RGRPP--IATFSANPEA----KGGEV 1 ( 1010) GPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQAGEV 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1488) VKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSA 1 ( 1070) VSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQ--------M 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1548) PGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPGRVAVNALAVGE 1 ( 1122) P--PTMVNNTGVVKIVVRQAP--RDGLTPVPPL---APAPRPPSSGLP--AVLNPRPTLT 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1608) PGTASKPA-----SPIGGPTQEEKTRLLKERLDQIYLVNERRCSQAPVYGRDLLRICALP 1 ( 1173) PGRLPTPTLGTARAPMPTPT........................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1663) SHGRVQWRGSLDGRRGKEAGPAHSYTSSSESPSELMLTLCRCGESLQDVIDRVAFVIPPV 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1723) VAAPPSLRV 1 ( -) ......... 2 ( -) ......... 3 ( -) ......... 4 ( -) ......... 5 ( -) ......... //