# 0 KIAA1251, 1483 aa # 1 KIAA0465 (4433 aa) # 2 KIAA0728 (1637 aa) # 3 KIAA0866 (1984 aa) # 4 KIAA0796 (1876 aa) // exp sw-scr id% from to 1 0 9431 100.0 1 1475 2 1.5e-05 537 20.4 11 1147 3 0.00015 506 20.8 850 1948 4 0.00019 418 19.2 147 1584 // 0 ( 1) KNTISVKAVCDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNK 1 ( 1) KNTISVKAVCDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 147) ...........................................................E // 0 ( 61) DAIEMASR-VEQSYQKVMALWHQLHVNTKSLISWNYLRKDLDLVQTW-NLEKLRSSAPGE 1 ( 61) DAIEMASR-VEQSYQKVMALWHQLHVNTKSLISWNYLRKDLDLVQTW-NLEKLRSSAPGE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 148) DLIKAKEKEVEKIEQNGLALIQNKKEDVSSIV-MSTLR---ELGQTWANLDHMVGQLKIL // 0 ( 119) CHQIMKNLQAHYEDFLQDSRDSVL----FSVADRLRLEE-EVEACKARFQHLMKSMENED 1 ( 119) CHQIMKNLQAHYEDFLQDSRDSVL----FSVADRLRLEE-EVEACKARFQHLMKSMENED 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 204) LKSVLDQWSSHKVAF--DKINSYLMEARYSLS-RFRLLTGSLEAVQVQVDNLQNLQDDLE // 0 ( 174) KEETVAKMYISELKNIRLRLEEYEQRVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQ-- 1 ( 174) KEETVAKMYISELKNIRLRLEEYEQRVVKRIQSLASSRTDRDAWQDNALRIAEQEHTQ-- 2 ( 11) ...............................QSIIS-QLPAPALEYETLRQQQEEHRQLR 3 ( -) ............................................................ 4 ( 261) KQERSLQKFGSITNQL---LKECHPPVTETLTNTLKEVNMR--WNNLLEEIAEQLQSS-- // 0 ( 232) EDLQQLRSDLDAVSMKCDSFLHQSPSSS--------SVPTLRSELNLLV----------E 1 ( 232) EDLQQLRSDLDAVSMKCDSFLHQSPSSS--------SVPTLRSELNLLV----------E 2 ( 39) ELIAEHKPHIDKMNKTGPQLLELSPGEGFSIQEKYVAADTLYSQIKEDV----------K 3 ( -) ............................................................ 4 ( 314) KALLQLWQRYKDYSKQCASTVQQQEDRT--------N-ELLKAATNKDIADDEVATWIQD // 0 ( 274) K----MDHVYGLSTVY--LNKLKTVDVIVRSIQDAELL--VKGYEIKLSQEEVVLAD--L 1 ( 274) K----MDHVYGLSTVY--LNKLKTVDVIVRSIQDAELL--VKGYEIKLSQEEVVLAD--L 2 ( 89) KRAVALDEAISQSTQF--HDK---IDQILESL---ERI--VE----RLRQPPSISAE--V 3 ( 850) ..................FTKVKPLLQVTR--QEEEMQ--AKEDELQKTKERQQKAENEL 4 ( 365) C----NDLLKGLGTVKDSLFVLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQ--- // 0 ( 324) SALEAHWSTL---RHWLSD-VKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERNLDLERYQ 1 ( 324) SALEAHWSTL---RHWLSD-VKDKNSVFSVLDEEIAKAKVVAEQMSRLTPERNLDLERYQ 2 ( 133) EKIKEQISEN---KNVSVD-MEKLQPLYETLKQR--GEEMIARSGGT---DKDISAKAVQ 3 ( 888) KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEE 4 ( 418) -ALCKQQTSL---QAGVLD-YETFAKSLEALEAWIVEAE---EILQGQDPSHSSDLSTIQ // 0 ( 380) EKGSQLQERWHRVIAQ---LEIRQSELESIQEVLGDYRACHGTLIKWIEETTA-QQEMMK 1 ( 380) EKGSQLQERWHRVIAQ---LEIRQSELESIQEVLGDYRACHGTLIKWIEETTA-QQEMMK 2 ( 184) DKLDQMVFIWENIHTL---VEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLED 3 ( 948) DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEIL-VMDDQN 4 ( 470) ERMEELKGQ----MLK---FSSMAPDLDRLNE-LGYRLPLNDKEIKRMQNLNR-HWSLIS // 0 ( 436) PGQAED-SRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFV 1 ( 436) PGQAED-SRVLSEQLSQQTALFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFV 2 ( 241) PGI--D-PSVVKQQQEAAETIREEIDGLQEELD-----------IVINLGSELIA--ACG 3 ( 1007) NKLSKE-RKLLEERISDLTTNLAEEEEKAKNLT---KLKNKHESMISELEVRL---KKEE 4 ( 521) SQTTERFSKLQSFLLQHQTFL----EKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAH // 0 ( 495) ESQQKSPGKRRRMLSS-----SDAITQEFMD-LRTRYTALVTLTTQHVKYISDALRRLEE 1 ( 495) ESQQKSPGKRRRMLSS-----SDAITQEFMD-LRTRYTALVTLTTQHVKYISDALRRLEE 2 ( 285) E-----PDK--------------PIVKKSIDELNSAWDSLN-------KAWKDRIDKLEE 3 ( 1060) KSRQELEKLKRKLEGD-----ASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDD 4 ( 577) ELFQAEMFSRQQILHSIIIDGQRLLEQGQVD-DRDEFNLKLTLLSNQWQGV---IRRAQQ // 0 ( 549) EEKVVEEE-KQ-----EHVEKVKELLGWVSTLARNTQGKATSSETKESTDI------EKA 1 ( 549) EEKVVEEE-KQ-----EHVEKVKELLGWVSTLARNTQGKATSSETKESTDI------EKA 2 ( 319) AMQAAVQY-Q---------DGLQAVFDWV-----DIAGGKLASMSPIGTDL------E-- 3 ( 1114) EIA----Q-KN-----NALKKIRELEGHISDLQEDLDSERAARNKAEK---------QKR 4 ( 633) RRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKV // 0 ( 597) ILEQQ---VLSEE----LTTKKEQVSEAIKTSQIFLAKHGHKLS----EKEKKQISEQLN 1 ( 597) ILEQQ---VLSEE----LTTKKEQVSEAIKTSQIFLAKHGHKLS----EKEKKQISEQLN 2 ( 356) TVKQQ---I--EE----L---KQFKSEAYQ-QQIEMERLNHQ-A----ELLLKKVTEESD 3 ( 1155) DLGEE---L--EA----LKTELEDTLDSTATQQELRAKREQEVT----VL-KKALDEETR 4 ( 693) FLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLK // 0 ( 646) ALNKAYHDLCDGSA--NQLQQLQSQLAH-QT--EQKTLQKQQNTCHQQLEDLCSWV---G 1 ( 646) ALNKAYHDLCDGSA--NQLQQLQSQLAH-QT--EQKTLQKQQNTCHQQLEDLCSWV---G 2 ( 398) K-HTVQDPLMELKLIWDSLEERIINRQH-KL--EGALLALGQ--FQHALDELLAWL---T 3 ( 1201) SHEAQVQEMRQKHA--QAVEELTEQLEQFKR--AKANLDKNKQTLEKENADLAGELRVLG 4 ( 753) DWEKCEKGIAD-SL--EKLRTFKKKLSQ-SLPDHHEELHAEQMRCKELENAVGSWT---D // 0 ( 698) Q-AERALAGH--QGRTTQQDLSALQK-------------NQSDLKDLQ-DDIQNRATSFA 1 ( 698) Q-AERALAGH--QGRTTQQDLSALQK-------------NQSDLKDLQ-DDIQNRATSFA 2 ( 449) H-TEGLLS----EQKPVGGDPKAIEI-------------ELAKHHVLQ-NDVLAHQSTVE 3 ( 1257) Q-AKQEVE-H--KKKKLEAQVQELQS-------------KCSDGERAR-AELNDKVHKLQ 4 ( 806) DLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFS // 0 ( 741) TVVKDIEGFMEENQTKLSP--RELTALREKLHQAKEQYE---ALQEETR----VAQK--E 1 ( 741) TVVKDIEGFMEENQTKLSP--RELTALREKLHQAKEQYE---ALQEETR----VAQK--E 2 ( 490) AVNKAGNDLIESS----AG--EEASNLQNKLEVLNQRWQ---NVLEKTE----QRKQ--Q 3 ( 1299) NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL------LQEETRQKLNVSTKLRQ 4 ( 866) EKNKELCEWLTQMESKVSQ--NGDILIEEMIEKLKKDYQEEIAIAQENK----IQLQ--Q // 0 ( 790) LEEAVTSALQQETEKSKAAKELAENKKKIDALLDWVTSVGSSGGQLLTNLPGMEQLSGAS 1 ( 790) LEEAVTSALQQETEKSKAAKELAENKKKIDALLDWVTSVGSSGGQLLTNLPGMEQLSGAS 2 ( 535) LD----GALRQ-------AKGF---HGEIEDLQQWLTDTER---HLLASKP----LGG-- 3 ( 1353) LEEERNSLQDQLDEEMEAKQNL---ERHISTLNIQLSDSKKKLQDFASTVEALEE-GKKR 4 ( 918) MGERLAKA-SHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDK-NMSS // 0 ( 850) LE------KGALDTTDGYMGVN--QAPEKLDKQCEMMK--ARHQEL---LSQQQNFILAT 1 ( 850) LE------KGALDTTDGYMGVN--QAPEKLDKQCEMMK--ARHQEL---LSQQQNFILAT 2 ( 572) LP------ETAKEQLNVHMEVC--AAFEAKEETYKSLM--QKGQQM---LAR------CP 3 ( 1409) FQ------KEIENLTQQYEEKA--AAYDKLEKTKNRLQ--QELDDLVVDLDNQRQLVSNL 4 ( 976) LRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTG---VASVLNL---- // 0 ( 897) QSAQAFLDQHGHNLTPEEQQMLQQKLGELKEQYSTSLAQSEAELKQVQTLQDELQKFLQD 1 ( 897) QSAQAFLDQHGHNLTPEEQQMLQQKLGELKEQYSTSLAQSEAELKQVQTLQDELQKFLQD 2 ( 613) KSAETNIDQDINNLK-EKWESVETKLNERKTK-----------LEEALNLAMEFHNSLQD 3 ( 1459) EKKQRKFDQ----LLAEEKNI-SSKYADERDR-----AEAEAREKETKALS--LARALEE 4 ( 1029) --CEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDD // 0 ( 957) HKEFESWLERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVL 1 ( 957) HKEFESWLERSEKELENMHKGGSSPETLPSLLKRQGSFSEDVISHKGDLRFVTISGQKVL 2 ( 661) ---FINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHR----------EQII 3 ( 1507) ALEAKEELERTNK-----------------MLKAE---MEDLVSSKDDV------GKNVH 4 ( 1087) YSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQV--HECLTQLELINKQ--- // 0 ( 1017) DMENSFKEGKEPSEIGN--LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSA 1 ( 1017) DMENSFKEGKEPSEIGN--LVKDKLKDATERYTALHSKCTRLGSHLNMLLGQYHQFQNSA 2 ( 708) ELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAW 3 ( 1541) ELEKS-KRALE-TQMEE--M-KTQLEELEDELQATEDAKLRLEVNMQALKGQFER----- 4 ( 1142) -YRRLARENRTDSACS----LKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETAR // 0 ( 1075) DSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEEL-AEHQVPVEKLQKVARD 1 ( 1075) DSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEEL-AEHQVPVEKLQKVARD 2 ( 768) SKLMEWLEESEKSLDSEL--EIANDPDKIKTQLAQHKEFQKSLGAKHSV-YDTTNRTGRS 3 ( 1591) -DLQA---RDEQNEEK-------------------RRQLQRQL-HEYETELEDERKQRAL 4 ( 1197) DSILVWL--TEMDLQ--LTNIEHFSECDVQAKIKQLKAFQQEI-SLNHNKIEQIIAQGEQ // 0 ( 1134) IMEIEGEPAPDHRHVQETTDSILSHFQSLSYSLAER--SSLLQKAIAQSQ-SVQESLESL 1 ( 1134) IMEIEGEPAPDHRHVQETTDSILSHFQSLSYSLAER--SSLLQKAIAQSQ-SVQESLESL 2 ( 825) LKE-KTSLADDNLKLDDMLSELRDKWDTICGKSVER--QNKLEEALLFSG-QFTDALQAL 3 ( 1627) AAAAKKKLEGDLKDLELQADSAIKGRE-------EA--IKQLRKLQAQMK-DFQRELEDA 4 ( 1252) LIE-KSEPL-DAAIIEEELDELRRYCQEV-FGRVERYHKKLIRLPLPDDEHDLSDRELEL // 0 ( 1191) LQSIGEVEQNLEG--KQVSSLSSGVIQ--EALATNMKLKQDIARQKSS-----------L 1 ( 1191) LQSIGEVEQNLEG--KQVSSLSSGVIQ--EALATNMKLKQDIARQKSS-----------L 2 ( 881) IDWLYRVEPQLAE--DQPVHGDIDLVM--NLIDNHKAFQKELGKRTSS-----------V 3 ( 1677) RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER-----ARKQAD-----------L 4 ( 1309) EDSAALSDLHWHD--RSADSLLSP--Q--PSSNLSLSLAQPLRSERSGRDTPASVDSIPL // 0 ( 1236) EATREM-VTRFMETADSTTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQ-AEMFE 1 ( 1236) EATREM-VTRFMETADSTTAAVLQGKLAEVSQRFEQLCLQQQEKESSLKKLLPQ-AEMFE 2 ( 926) QALKRS-ARELIEGSRDDSSWV-KVQMQELSTRWETVCALSISKQTRLEAALRQ-AEEFH 3 ( 1721) E--KEE-LAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEA-------MSD 4 ( 1363) EWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVALSGDHSALESQIRQLGKALD // 0 ( 1294) HLSGKLQQFM-ENKSRMLASGNQPDQD--ITHFFQQIQELNLEMEDQQENLDTLEHLV-T 1 ( 1294) HLSGKLQQFM-ENKSRMLASGNQPDQD--ITHFFQQIQELNLEMEDQQENLDTLEHLV-T 2 ( 983) SVVHALLEWLAEAEQTLRFHGVLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDT 3 ( 1770) RVRKATQQ-A-EQLSNELATERSTAQK--NESARQQLERQNKELRSK---LHEMEGAVKS 4 ( 1423) DSRFQIQQ-T-ENIIRS-KTPTGPELD--TS--YKGYMKLLGECSSSIDSVKRLEHKL-K // 0 ( 1350) EL--SSCGF-ALD--LCQHQDRVQNLRKDFTELQKTVKEREKDASSCQEQLDEFRKLVRT 1 ( 1350) EL--SSCGF-ALD--LCQHQDRVQNLRKDFTELQKTVKEREKDASSCQEQLDEFRKLVRT 2 ( 1043) VL--AICHPDSIT--TIKHW--ITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEA 3 ( 1823) KF--KSTIA-ALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 4 ( 1475) EEEESLPGF--VN--LHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNS // 0 ( 1405) FQKWLKETEGSIPPT---ETSMSAKELEKQIEHLKSLLDDWASKGTLVEEIN-CKGTSLE 1 ( 1405) FQKWLKETEGSIPPT---ETSMSAKELEKQIEHLKSLLDDWASKGTLVEEIN-CKGTSLE 2 ( 1097) LLAWLQWAETTL-------TDKDKEVIPQEIEEVKALI---AEHQTFMEEMT-RKQPDVD 3 ( 1880) YKEQAEKGNARVKQL---KRQLEEAEEESQRIN--------ANRRKLQRELD-EATESNE 4 ( 1531) IWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLC...... // 0 ( 1461) NLIMEITAPDSQGKTGEYRLFKI 1 ( 1461) NLIMEITAPDSQGKT........ 2 ( 1146) KV..................... 3 ( 1928) AMGREVNALKSKLRRGNETSF.. 4 ( -) ....................... //