# 0 KIAA0389, 1296 aa # 1 KIAA1119 (1854 aa) # 2 KIAA0727 (1010 aa) # 3 KIAA1000 (1956 aa) # 4 KIAA0866 (1984 aa) # 5 KIAA0865 (1900 aa) // exp sw-scr id% from to 1 1.6e-19 1711 30.5 18 1094 2 2.3e-15 1305 31.0 6 817 3 7.3e-12 1478 30.8 59 1064 4 4.5e-08 1649 30.9 30 1165 5 4.7e-08 966 28.9 420 1198 // 0 ( 1) WKQEIVDPPSKMED---GKP-VWAPHPTDGFQMGNIV-DI--GPD-SLTIEPLNQKGKTF 1 ( 18) .....................VWIPDPDEVWRSAELTKDYKEGDK-SLQLRLEDETILEY 2 ( -) ............................................................ 3 ( 59) .............D---GKKKCWIPDGENAYIEAEVK-GS--EDDGTVIVETADGESLSI 4 ( 30) ..KNFINSPVAQADWAAKRL-VWVPSEKQGFEAASIK-EE--KGD-EVVVE-LVENGKKV 5 ( 420) ............................................D-SIPENPM-MSGSTK // 0 ( 53) LA-LI--NQV-FPAEEDSKKDVEDNCSLM-YLNEATLLHNIKVRY-SKDRIYTYVANILI 1 ( 56) PI-DVQRNQLPFLRNPDILVGENDLTALS-YLHEPAVLHNLKVRFLESNHIYTYCGIVLV 2 ( 6) .............AEQESLEFGKADFVLMDTVSMPEFMANLRLRF-EKGRIYTFIGEVVV 3 ( 100) KEDKI--QQM-NPPEFEM---IEDMAMLT-HLNEASVLHTLKRRY-GQWMIYTYSGLFCV 4 ( 82) TV-GK--DDI-QKMNPPKFSKVEDMAELT-CLNEASVLHNLRERY-FSGLIYTYSGLFCV 5 ( 434) PE-QV--KLM-PPAPND------DLATLS-ELNDGSLLYEIQKRF-GNNQIYTFIGDILL // 0 ( 107) AVNPYFDIPKIYSSEAIKSY---QGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGE 1 ( 114) AINPYEQLP-IYGQDVIYAY---SGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGE 2 ( 52) SVNPY-KLLNIYGRDTIEQY---KGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGE 3 ( 152) TINPYKWLP-VYQKEVMAAY---KGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGE 4 ( 136) VVNPYKHLP-IYSEKIVDMY---KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGE 5 ( 482) LVNPYKELP-IYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGE // 0 ( 164) SGAGKTENTKFVLRY------LT--ESYGTGQ-------D-----IDDRIVEANPLLEAF 1 ( 170) SGAGKTVSAKYAMRY------FA--TVGGSAS-------ETN---IEEKVLASSPIMEAI 2 ( 108) SGAGKTEASKYIMQY------IA--AITNPSQ-------RAEVERVKNMLLKSNCVLEAF 3 ( 208) SGAGKTVNSKHIIQYFATIAAMI--ESRKKQG-------A-----LEDQIMQANTILEAF 4 ( 192) SGAGKTENTKKVIQY------LAVVASSHKGKKDTSITGE-----LEKQLLQANPILEAF 5 ( 541) RGSGKSEASKQIIRH------LT--CRAGASRA------T-----LDSRFKHVVCILEAF // 0 ( 204) GNAKTVRNNNSSRFGKFVEIHFNE-KSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRL 1 ( 212) GNAKTTRNDNSSRFGKYIQIGFDK-RYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQL 2 ( 153) GNAKTNRNDNSSRFGKYMDINFDF-KGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQL 3 ( 254) GNAKTLRNDNSSRFGKFIRMHFGA-RGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQI 4 ( 241) GNAKTVKNDNSSRFGKFIRINFDV-TGYIVGANIETYLLEKSRAIRQARDERTFHIFYYM 5 ( 582) GHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLL // 0 ( 263) CAGASEDIREKLHLSS-PDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPL 1 ( 271) CAAAGLPEFKELALTS-AEDFFYTSQG--------------------------GDTSIEG 2 ( 212) LQGGSEQMLRSLHLQ---------------------------KSLSSYNYIHVGAQLKSS 3 ( 313) LSGQKE-LHDLLLVSANPSDFHF----CS-----------------------CGAVTVES 4 ( 300) IAGAKEKMRSDLLLEG-FNNYTFLSNG----------------------FVPIPAAQDDE 5 ( 642) MDGLSAEEKYGLHLNN-LCAHRYLNQTIQ---DDASTGERSL-NREKLAVLK-------- // 0 ( 322) LDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAQ 1 ( 304) VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQ-AERDGDSCSISPQDVY 2 ( 245) INDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTP---LIENGKVV 3 ( 345) LDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREE---QLEADGTE 4 ( 337) M-----FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQ 5 ( 689) -----------RALNVVGFSSLEVENLFVILAAILHLGDIRFT---ALNEGNSAFVSDLQ // 0 ( 382) SLEYCAELLGLDQDDL-RVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYS 1 ( 363) LSNFC-RLLGVEHSQM-EHWLCHRKLVTTSE----TYVKT-MSLQQVINARNALAKHIYA 2 ( 302) SI--IAELLSTKTDMV-EKALLYR---TVATGRD--IIDKQHTEQEASYGRDAFAKAIYE 3 ( 402) NADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTI------EQVTCAVGALSKSMYE 4 ( 392) KV--C-HLMGINVTDFTRSILTPRIKV----G-RDVVQKAQTK-EQADFAVEALAKATYE 5 ( 735) LLEQVAGMLQVSTDEL-ASALTTDIQYF-----KGDMIIRRHTIQIAEFFRDLLAKSLYS // 0 ( 441) HLFDHVVNRVNQCFP---FET-----S-SY----FIGVLDIAGFEYFEHNSFEQFCINYC 1 ( 416) QLFGWIVEHINKALH---TSL-----K-QHS---FIGVLDIYGFETFEVNSFEQFCINYA 2 ( 354) RLFCWIVTRINDIIEVKNYDT-----T-IHGKNTVIGVLDIYGFEIFDNNSFEQFCINYC 3 ( 456) RMFKWLVARINRALD---AKL-----SRQF----FIGILDITGFEILEYNSLEQLCINFT 4 ( 443) RLFRWILTRVNKALDKT-HRQ-----G-AS----FLGILDIAGFEIFEVNSFEQLCINYT 5 ( 789) RLFSFLVNTMNSCLH---SQDEQKSMQ-TL----DIGILDIFGFEEFQKNEFEQLCVNMT // 0 ( 488) NEKLQQFFNERILKEEQELYQKEGLGVNEVHY-VDNQDCI-DLIE--AKLVGILDILDEE 1 ( 464) NEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDF-YDNQPCI-DLIE--AKL-GILDLLDEE 2 ( 408) NEKLQQLFIQLVLKQEQEEYQREGIPWKHIDY-FNNQIIV-DLVE--QQHKGIIAILDDA 3 ( 504) NEKLQQFFNWYMFVLEQEEYKKESIEWVSIGFGLDLQACI-DLIE---KPMGILSILEEE 4 ( 492) NEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI-ELIERPNNPPGVLALLDEE 5 ( 841) NEKMHHYINEVLFLHEQVECVQEGVTMETAYS-AGNQNGVLDFFF--QKPSGFLTLLDEE // 0 ( 544) N-RLPQPSDQHFTSAVHQKH--KD-HFRLTIPRKSKLAVHRNIRDDEG--FIIRHFAGAV 1 ( 519) C-KVPKGTDQNWAQKLYDRH--SS-SQHFQKPRMSNTA------------FIIVHFADKV 2 ( 464) CMNVGKVTDEMFLEALNSKL--GK-HAHFS-SRKL-CASDKILEFDRD--FRIRHYAGDV 3 ( 560) C-MFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAH----------FELVHYAGVV 4 ( 551) C-WFPKATDKSFVEKLCTEQ--GS-HPKFQKPKQ--------LKDKTE--FSIIHYAGKV 5 ( 898) S-QMIWSVESNFPKKLQSLL--ES-SNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRV // 0 ( 598) CYETTQFVEKNNDALHMSLESLICESRDKFIRELF-ESS------------TNN------ 1 ( 563) EYLSDGFLEKNRDTVYEEQINILKASKFPLVADLF-HDD------------KDP------ 2 ( 517) VYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGK------------LSI------ 3 ( 609) PYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF-ENY------------MST------ 4 ( 597) DYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW-KDVDRIVGLDQMAKMTES------ 5 ( 954) MYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLF-QSK------------LSQTGSLVS // 0 ( 639) ---------------------------NK-----D----TK--QKAGKLSF--------- 1 ( 604) ---------------------------VP-----A----TT--PGKGSSSK--------- 2 ( 559) ---------------------------TE-----V----TK--RP--------------- 3 ( 650) ---------------------------DSAIPFGE----KK--RKKGA-SF--------- 4 ( 650) ---------------------------SL-----P----SA--SKTKKGMF--------- 5 ( 1001) AYPSFKFRGHKSALLSKKMTASSIIGENK-----NYLELSKLLKKKGTSTFLQRLERGDP // 0 ( 652) ISV------------------GNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEG 1 ( 617) ISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDP 2 ( 566) LTA------------------ATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDD 3 ( 667) QTV------------------ASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGILDP 4 ( 663) RTV------------------GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDA 5 ( 1056) VTI------------------ASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDN // 0 ( 694) AQILSQLQCSGMVSVLDLMQGGYPSR---ASFHEL---YNMYKKYM-PDK-LAR--LDPR 1 ( 677) KRAVQQLRACGVLETIRISAAGYPSR---WAYHDF---FNRYRVLV-KKRELAN--TDKK 2 ( 608) ERCRHQVEYLGLLENVRVRRAGFAFR---QTYEKFLHRYKMISEFTWPNH-DLP--SD-K 3 ( 709) YLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQR---YCILNPRT-FPK-SKF--VSSR 4 ( 705) FLVLEQLRCNGVLEGIRICRQGFPNR---IVFQEF---RQRYEILA-ANA-IPKGFMDGK 5 ( 1098) FYVSAQLQYIGVLEMVKIFRYGYPVR---LSFSDF---LSRYKP-L-ADT-FLR--EKKE // 0 ( 744) LF----CKALFKALGLNENDYKFGLTKVFFR-PGKFAEFDQIMKSD---PDHLAELV--K 1 ( 728) AI----CRSVLENLIKDPDKFQFGRTKIFFR-AGQVAYLEK-LRAD---KFRTATIMIQK 2 ( 661) EA----VKKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQM---LIRIVLFL--Q 3 ( 762) KA----AEELLGSLEIDHTQYRFGITKVFFK-AGFLGQLEAIRD---------------E 4 ( 757) QA----CILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEE--ERDLKITDVIMAFQ--A 5 ( 1147) QSAAERCRLVLQQCKLQ--GWQMGVRKVFL----KYWHADQLN-------DLCLQLQ--R // 0 ( 794) RVNHW---LTCSRWKKVQWCSLSVIKL--KNKIKYR-AEACIKMQKTIRMWLCKRRHKPR 1 ( 779) TVRGW---LQKVKYHRLKGATLTLQRYC-RGHLARRLAEHLRRIRAAVVLQKHYRMQRAR 2 ( 711) KV--WRGTLARMRYKRTK-AALTIIRYYRRYKVKSY-IHEVARRFHGVKTMRDYGKH--- 3 ( 802) RLSKV---FTL--FQARAQGKLMRIKF--QKILEER--DALILIQWNIRAFMAVK-NWPW 4 ( 808) MCRGY---LARKAFAKRQQ-QLTAMKV-----IQRN-CAAYLKL-RNWQWWRLFTKVKP- 5 ( 1192) KI------ITCQK............................................... // 0 ( 848) IDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEIS-IDTLMAKIKSTMMTQE-- 1 ( 835) -QAYQRVRRAAVVIQAFTRAMFVRRT-----YRQVL-MEHK-ATTIQKHVRG-WMARR-- 2 ( 764) ----VKWPSPPKVLRRFEEALQTIFN-RWRASQLIKSIPASDLPQVRAKVAAVEMLKG-- 3 ( 852) MRLFFKIKPLVKS-SEVGEEVAGLKEECAQLQKALEKSEFQ-REEL--KAKQVSLTQEKN 4 ( 856) ---LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQK-HSQLTEEKN---LLQE-- 5 ( -) ............................................................ // 0 ( 905) ----QIQKEYDA--LVKSSEELLSA---LQKKKQQEEEA--ERLRRIQEE------MEKE 1 ( 884) ----HFQRLRDAAIVIQCAFRMLKARRELKALRIEARSA--EHLKRLNVG------MENK 2 ( 817) ----Q....................................................... 3 ( 908) DLILQLQAEQET--LA-NVEEQCEW---LIKSKIQLE----ARVKELSER------VEEE 4 ( 907) ----QLQAETE---LYAEAEEMRVR---LAAKKQELEEILHEMEARLEEEEDRGQQLQAE 5 ( -) ............................................................ // 0 ( 948) --RKRREE---DEKRRRKEEEE-RRMKLE-----MEAKRKQEE---EERKKREDDEKRIQ 1 ( 932) VVQLQRKI---DEQNKEFKTLS-EQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQ 2 ( -) ............................................................ 3 ( 952) --EEINSE---LTARGRKLEDECFELKKEIDD--LETMLVKSE---KEKRTTEHKVKNLT 4 ( 957) --RKKMAQQMLDLEEQLEEEEA-ARQKLQ-----LE---KVTA---EAKIKKLEDEILVM 5 ( -) ............................................................ // 0 ( 994) AEVE------AQLARQKE--EESQQQ---AVLEQERRDR-ELA-LRIAQSEAE--LISDE 1 ( 988) EEVE------SLRTELQR--AHSERK---ILEDAHSREKDELR-KRVADLEQENALLKDE 2 ( -) ............................................................ 3 ( 1002) EEVEFLNEDISKLNRAAKVVQEAHQQ---TLDDLHMEEE-KLSSLSKANLKLE--QQVDE 4 ( 1003) DDQN------NKLSKERKLLEERISDLTTNLAEEEEKAK-NLT--KLKNKHES--MISE- 5 ( -) ............................................................ // 0 ( 1039) AQA---DLALRRNDGTRPKMTP--EQ--MAKEMSEF---LSRGPAVLATKAAAGTKKYDL 1 ( 1036) KEQLNNQILCQSKDEFAQNSVK--ENLLMKKELEEE---RSRYQNLV--------KEYSQ 2 ( -) ............................................................ 3 ( 1056) LEG---ALEQER................................................ 4 ( 1051) --L---EVRLKKEEKSRQELEKLKRK--LEGDASDFHEQIADLQAQIAELKMQLAKKEEE 5 ( -) ............................................................ // 0 ( 1089) SKWKYAELRDTI----NTSCDIELLAACREEFHRRLKVYHAWKSK--NKKRNTETEQRAP 1 ( 1083) LEQRYDNLRDEM................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1104) LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 5 ( -) ............................................................ // 0 ( 1143) KSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKG 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1164) KT.......................................................... 5 ( -) ............................................................ // 0 ( 1203) WWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEE 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1263) IWERCGGIQYLQNAIESRQARPTYATAMLQSLLK 1 ( -) .................................. 2 ( -) .................................. 3 ( -) .................................. 4 ( -) .................................. 5 ( -) .................................. //