# 0 KIAA0577, 1043 aa # 1 KIAA0224 (1256 aa) # 2 KIAA1488 (852 aa) # 3 KIAA0134 (587 aa) # 4 KIAA0890 (1210 aa) # 5 KIAA1517 (998 aa) // exp sw-scr id% from to 1 2.7e-66 2353 40.7 255 1182 2 2e-15 1071 32.4 44 755 3 2.2e-14 935 31.9 15 546 4 3.3e-11 1003 29.1 203 1090 5 3.4e-10 1201 32.6 56 852 // 0 ( 1) VAMATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGP 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) ARDFALRLWNKVPRKAVVEKPA-----RAAEREAR-ALLEKNRSYRLLEDSEESSEETVS 1 ( 255) .............RRSQWESPSPTPSYRDSERSHRLSTRDRDRSVR----GKYSDDTPLP 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 115) RAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERL 1 ( 298) TPSYKYNEWADDRRHLGST-----PRLSRGRGRREEGEEGISFDTEEERQQWEDDQRQAD 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 203) ..................REEEEDEEEELEEGTIDVTDFLSMTQQDSHAPL--RDSRGSS 5 ( -) ............................................................ // 0 ( 175) QDLEERDAFAERVRQRD--KDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRK-K 1 ( 353) RDWYMMDEGYDEFHNPL--AYSSEDYVRRREQHLHKQKQKRI--SAQRRQINEDNERW-E 2 ( -) ............................................................ 3 ( 15) .....................................................PRTREGR 4 ( 243) FEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLW-P 5 ( -) ............................................................ // 0 ( 232) SRREYL-AK--REREKLEDLEAELADE----------EFLFGDVELSRHERQELKYKRRV 1 ( 408) TNRMLT-SGVVHRLEVDEDFEEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDAT 2 ( -) ............................................................ 3 ( 22) DRRDHHRAP--SEEEALEKWDWNCPET----------RRLLEDAFF----REE-DYIRQG 4 ( 302) CPMTFV-AKG-RRKAEAENKAAALACK----------KL----KSLGLVDRNNEPLTHAM 5 ( -) ............................................................ // 0 ( 279) RDLAREYRAAGEQ-EKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLG 1 ( 467) SDLAIIARK-GSQ------TVRKHREQKERKKA----------------QHKHWE----- 2 ( -) ............................................................ 3 ( 65) SEECQKFWTFFERLQRFQNLKTSRKEEKDPGQPKHSIPALADLPRTY-DPRYRINLSVLG 4 ( 346) YNLAS-LRELGET-QRRPCT--IQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILP 5 ( -) ............................................................ // 0 ( 338) AASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV 1 ( 499) LAGTKLGDIMGVKKEEEPDKAVTEDGKVDY-RTEQKFADHMKRKSEASSEFAKKKSILEQ 2 ( 44) ........................................................MQHF 3 ( 124) PATR--GSQGLGRHLPA-------ERVAEFRRALLHYLDFGQKQAFGRLAKLQRE----- 4 ( 402) LGKDSGPLSDPITGKP-YVPLLEAEE----VRLSQSLLELWRRRGPVWQEAPQ------- 5 ( 56) ............................................PAVFIPVNRSPEMQEE // 0 ( 398) RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGM----KIAC- 1 ( 558) RQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGM-----IGC- 2 ( 48) REKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDN-YIERGKGSACRIVC- 3 ( 170) RAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH--------VAC- 4 ( 450) ---LPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGR----GARCN 5 ( 72) RLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQVPQFLYEAGFSSEDS----IIGV- // 0 ( 453) ---TQPRRVAAMSVAARVA--REMGVKLGNEVGYSIRFEDCTSER--T-VLRYMTDGMLL 1 ( 612) ---TQPRRVAAMSVAKRVS--EEMGGNLGEEVGYAIRFEDCTSEN--T-LIKYMTDGILL 2 ( 106) ---TQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGS-IL-YCTTGIIL 3 ( 221) ---TQPRRIACISLAKRVG--FESLSQYGSQVGYQIRFESTRSAA--T-KIVFLTVGLLL 4 ( 502) VIITQPRRISAVSVAQRVS--HELGPSLRRNVGFQVRLESKPPSR--GGALLFCTVGILL 5 ( 127) ---TEPRRVAAVAMSQRVA--KEMNLSQ-RVVSYQIRYEGNVTEE--T-RIKFMTDGVLL // 0 ( 505) REFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPE----LKVLVASATMDTA 1 ( 664) RESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSD----LKLIVTSATMDAE 2 ( 161) QWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD----LKVILMSATLNAE 3 ( 273) RQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPD----LKVILMSATINIS 4 ( 558) RKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPA----LRLVLMSATGDNE 5 ( 178) KEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKLLIMSATLRVE // 0 ( 561) RFST----FFDDAPVFRIPGRRFPV------DIF--Y-----TK-APEA----------- 1 ( 720) KFAA----FFGNVPIFHIPGRTFPV------DIL--F-----SK-TPQE----------- 2 ( 217) KFSE----YFGNCPMIHIPGFTFPVVEYLLEDVIEKI-----RY-VPEQKEHRSQFKRGF 3 ( 329) LFSS----YFSNAPVVQVPGRLFPI------TVF-------------------------- 4 ( 614) RFSR----YFGGCPVIKVPGFMYPV------KEH--YLEDILAK-LGKH----------- 5 ( 238) DFTQNPRLFAKPPPVIKVESRQFPV------TVH--F-----NKRTPLE----------- // 0 ( 592) ----------------------DYL---------E-------ACVVS-------VLQIH- 1 ( 751) ----------------------DYV---------E-------AAVKQ-------SLQVH- 2 ( 267) MQGHVNRQEKEEKEAIYKERWPDYV---------RELRRRYSASTVD-------VIEMME 3 ( -) ------------------------------------------------------------ 4 ( 650) ----------------------QYLHRHRHHESED-------ECALDLDLVTDLVLHID- 5 ( 274) ----------------------DYS---------G-------ECFRK-------VCKIH- // 0 ( 606) -----------------VTQPPGDILVFLTGQEEIEAACEMLQ----------------- 1 ( 765) -----------------LSGAPGDILIFMPGQEDIEVTSDQIV----------------- 2 ( 311) DDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLM----------------- 3 ( 353) -----------------------DV----------------------------------- 4 ( 680) -----------------ARGEPGGILCFLPGWQEIKGVQQRLQ----------------- 5 ( 288) -----------------RMLPAGGILVFLTGQAEVHALCRRLRKAFPPSRARPQEKDDDQ // 0 ( 632) ----DRCRRL------------------------------GSKIRE-------------- 1 ( 791) ----EHLEEL-------------------------------ENAPA-------------- 2 ( 354) ----SQ---V------------------------------MFKSDK-------------- 3 ( -) ------------------------------------------------------------ 4 ( 706) ----EA---L------------------------------GMHESK-------------- 5 ( 331) KDSVEEMRKFKKSRARAKKARAEVLPQINLDHYSVLPAGEGDEDREAEVDEEEGALDSDL // 0 ( 644) --------------------LLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSL 1 ( 802) --------------------LAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVATNIAETSL 2 ( 363) --------------------FLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSI 3 ( 355) -----------------------------------------APPGVRKCILSTNIAETSV 4 ( 715) --------------------YLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSI 5 ( 391) DLDLGDGGQDGGEQPDASLPLHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSL // 0 ( 684) TIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAW 1 ( 842) TVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLYTQS 2 ( 403) TIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNGL 3 ( 374) TIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYAES 4 ( 755) TINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPR- 5 ( 451) TIPGIKYVVDCGKVKKRYYDRVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSA // 0 ( 744) AYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHF--DFL----DPPPYETLLLALEQ 1 ( 902) AYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQF--HFM----DPPPEDNMLNSMYQ 2 ( 463) -RASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLM----DPPSNEAVLLSIRH 3 ( 434) DYD-AFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTF--PFI----EPPPPASLETAILY 4 ( 814) SRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAV--EFLSKAVDSPNIKAVDEAVIL 5 ( 511) VFG-DFEQFPPPEITRRPVEDLILQMKALNVEKVINF--PFP----TPPSVEALLAAEEL // 0 ( 798) LYALGAL--------------NHLG-ELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI 1 ( 956) LWILGAL--------------DNTG-GLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEI 2 ( 518) LMELNAL--------------DKQE-ELTPLGVHLARLPVEPHIGKMILFGALFCCLDPV 3 ( 487) LRDQGAL--------------DSSE-ALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPV 4 ( 871) LQEIGVL--------------DQRE-YLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPL 5 ( 564) LIALGALQPPQKAERVKQLQENRLSCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYA // 0 ( 843) LTVAAMLSVNNSIFYRPKDKVVHADN---------ARVNF-F----------LPG-GDHL 1 ( 1001) LLIVSMLSVP-AIFYRPKGREEESDQ---------IREKF-A----------VPE-SDHL 2 ( 563) LTIAASLSFKDP-FVIPLGKEKIADA---------RRKEL-A----------KDTRSDHL 3 ( 532) LTIAAALSVQ-SPFTR............................................ 4 ( 916) LVVVSCLTRDP--FSSSLQNRAEVDK---------VKALLSH----------DSG-SDHL 5 ( 624) ITIVASMTVRE--LFEELDRPAASDEELTRLKSKRARVAQ-MKRTWAGQGASLKL-GDLM // 0 ( 882) VLLNVYTQWAE----S---G--YSSQWCY--ENFVQFRSMRRARDVREQL-EGLLERV-- 1 ( 1039) TYLNVYLQWKN----N---N--YSTIWCN--DHFIHAKAMRKVREVRAQL-KDIMVQQ-- 2 ( 602) TVVNAFEGWEE----ARRRGFRYEKDYCW--EYFLSSNTLQMLHNMKGQFAEHLLGAG-- 3 ( -) ............................................................ 4 ( 954) AFVRAVAGWEEVLRWQ---D--RSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAF-- 5 ( 680) VLLGAVGACEY----A---S--CTPQFCE--ANGLRYKAMMEIRRLRGQL-TTSVNAVCP // 0 ( 928) EVG------L-------SSCQ-GDYIR----VRKA-ITAGYFYHTA--RLT--------- 1 ( 1085) RMS------L-------ASCG-TDWDI----VRKC-ICAAYFHQAA--KLK--------- 2 ( 654) FVS------SRNPKDPESNIN-SDNEK----IIKAVICAGLYPKVAKIRLN--------- 3 ( -) ............................................................ 4 ( 1007) LVGKPSDCTL-------ASAQCNEYSEEEELVKGV-LMAGLYPNLI--QV---------- 5 ( 728) EAE------LFVDPKMQPPTE-SQVTY----LRQI-VTAGLGDHLA--RRVQSEEMLEDK // 0 ( 958) -RSG-YRTV-----KQQQTVFIHPNSSLFEQ--QP---RWLLYHELVLTTKEFMRQVLEI 1 ( 1115) -GIGEYVNI-----RTGMPCHLHPTSSLFGMGYTP---DYIVYHELVMTTKEYMQCVTAV 2 ( 694) -LGK-KRKMVKVYTKTDGLVAVHPKSVNVEQ--TDFHYNWLIYHLKMRTSSIYLYDCTEV 3 ( -) ............................................................ 4 ( 1047) -RQG--KVT-----RQGK---FKPNSVTYRT--KS---GNILLHKSTIN-----REATRL 5 ( 774) WRNA-YKTP-----LLDDPVFIHPSSVLFKE--LP---EFVVYQEIVETTKMYMKGVSSV // 0 ( 1006) ESSWLLEVAPHYYK-AKELEDPHAKKMPKKIGKTREELG 1 ( 1166) DGEWLAELGPMFYS-VKQ..................... 2 ( 750) SPYCLL................................. 3 ( -) ....................................... 4 ( 1086) RSRWL-................................. 5 ( 823) EVQWIPALLPSYCQFDKPLEEPAPTYCPER......... //