# 0 KIAA1074, 1715 aa # 1 KIAA0565 (641 aa) # 2 KIAA1641 (718 aa) # 3 KIAA2015 (996 aa) # 4 KIAA1561 (1416 aa) # 5 KIAA1334 (989 aa) // exp sw-scr id% from to 1 1.2e-37 2107 50.5 6 625 2 7.2e-13 1647 46.3 119 706 3 8.4e-13 1855 42.5 255 993 4 4.5e-07 634 22.2 6 1398 5 1.9e-06 464 21.8 39 977 // 0 ( 1) SPVAWAMKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDL-GK--IH 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 6) ......................SRLRRQDVPGPASSGAAAASAHAADWNKYD--DR--LM 5 ( 39) ...............................GDAEKVASLLGKKGASATKHDSEGKTAFH // 0 ( 58) KAASAGNVAKVQQILLLRKNGLNDR--DKMNRTALHLACANGHPEVVTLLVDRKCQLNVC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 40) KAAERGDVEKVTSILA--KKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTS 5 ( 68) LAAAKGHV-ECLRVMITHGVDVTAQ--DTTGHSALHLAAKNSHHECIRKLLQSKCPAESV // 0 ( 116) DNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYD 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 98) DTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHG 5 ( 125) DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG // 0 ( 176) ANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLIS-EYKEERIPK 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 158) ASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVE 5 ( 185) ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYS-KLSE----- // 0 ( 235) HSSQNSNSVDESSEDSLSRLSGKPGVDDSWPTSDDEDLNFDTK-NVPKPSLAKLMTASQQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 218) --VLIKNGADISLLDAL-------GHDSSYYARIGDNLDI----------LTLLKTASEN 5 ( 239) NAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVS // 0 ( 294) SRKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKP 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 259) TNKGRELWKKGPSLQQRNL-----THMQDEVNVKSHQREHQNIQ----------DL---- 5 ( 299) SPRSITST---PLSGKESVFF---AEPPFKAEISSIRENKDRL---SDSTTGADSLLDIS // 0 ( 354) SHKSLANP-GLMKEEPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 300) ---EIENE-DL-KERLRK---IQQEQRILLDKVNGLQLQLNEEVMVADDL-ESEREKLKS 5 ( 350) SEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEA--DLSF-DSYH-STQTDLGP // 0 ( 413) ALGLGQEEDIESPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGS 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 351) LLAAKEKQHEESLRTIEALKNRFKYFESDHL-----GSGSHFSNRK-EDMLLKQGQMY-- 5 ( 406) SLGKPGET---SPPDSKSS----PSVLIHSLGKSTTDNDVRI--QQLQEIL-----QDLQ // 0 ( 473) RNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSK----AA 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 403) ----MADSQCT-SPGIP-AHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESA 5 ( 452) KRLESSEAERKQ---LQV-ELQSRRAELVCLNNTEISENSSDLSQKLKETQ-SK----YE // 0 ( 529) EHDLEVASEEEQEREGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLI 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 457) KQD-RLKLQNELAHKVAECKALALECERVKEDSDEQ--IKQLEDALKDVQKRMYESEG-- 5 ( 503) EAMKEVLSVQKQMKLGLVSPE-SMDNYSHFHELRVTEEEINVLKQDLQNALEESERN--- // 0 ( 589) QKRKSGETDHQQFPRKENKEYASGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGG 1 ( -) ............................................................ 2 ( 119) ............................................TLKATIENKNSVLNTA 3 ( -) ............................................................ 4 ( 512) -KVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEV-GK---LRNQ 5 ( 559) -KEKVRELE-EKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEE // 0 ( 649) LLQVDDD--SSLSEID-----EDEGRPTKKTSN----EKNKVKNQIQSM-----DDVDDL 1 ( -) ............................................................ 2 ( 135) TKMKDVQ--TSTPEQDLEMASEGEQKRLEEYEN----NQPQVKNQIHSR-----DDLDDI 3 ( -) ............................................................ 4 ( 567) IKQ--NE--MIVEEFK-----RDEG----KLIE----ENKRLQKEL-SM----------- 5 ( 617) IMKLKDTLKSQMTQEA-----SDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDY // 0 ( 693) TQSSETASEDCELPHSS-YKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKK--- 1 ( -) ............................................................ 2 ( 184) IQSSQTVSEDGDSLCCN-CKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKD--- 3 ( -) ............................................................ 4 ( 598) ----------CEMEREK-KGRKVTEMEGQAKELSAKLAL------SIPAEKFENMKS--- 5 ( 672) RKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNE-LTQLKQLVD // 0 ( 749) ----------NHCELLTV---KIKKMEDKVNVLQRELSETKEIK-SQLEHQKVEWERELC 1 ( -) ............................................................ 2 ( 240) ----------NHCEQLRV---KIRKLKNKASVLQKRISEKEEIK-SQLKHEILELEKELC 3 ( -) ............................................................ 4 ( 638) ----------SLSNEVNE---KAKKLVEMEREHEKSLSEIRQLK-RELENVKAKLAQHV- 5 ( 731) AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLA-SKEVEVAKLEKQLLEEKAAMT // 0 ( 795) SLRFSLNQEEEKRRNADT----LYEKIREQLRRKEE------QYRKEV-EVKQQLELSLQ 1 ( 6) ..RLALKQENEEKRNADM----LYNKDSEQLRIKEE------ECGKVV-ETKQQLKWNLR 2 ( 286) SLRFAIQQEKKKRRNVEE----LHQKVREKLRITEE------QYRIEA-DVTKPIKPALK 3 ( 255) ...........................................................Q 4 ( 683) -------KPEE------------HEQVKSRLEQKSG------ELGKKI-T---ELTLKNQ 5 ( 790) DAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKE-NIQ // 0 ( 844) TLEMELRTVKSNLNQVVQERNDAQ-RQLSR-----EQNARMLQD-GILTNHLSKQKEIEM 1 ( 53) RLVKELRTVRNNLDLVVQERNDAQ-KQLSE-----EQDARILQD-QILT---SKQKELEM 2 ( 335) SAEVELKTGGNNSNQV-------------------------------------------- 3 ( 256) ILEHKNKMLKNHLRNDNQETAAMKPANLKK-----RKERAKAEH-NLKVASEEKQERLQR 4 ( 714) TLQKEIEKVYLD-NKLLKEQA----HNLTI-----E-----------MKNHYVPLKVSED 5 ( 849) TL---LKSKEQEVNELLQKFQQAQ-EELAEMKRYSESSSKLEEDKDKKINEMS--KEVTK // 0 ( 897) AQKKMNSEN--SHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQE--KEKKCFEDLK 1 ( 103) ARKKMNSEI--SHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQ--KEKKYFEDIE 2 ( 351) ------SET------DEKEDLLHENRLMQDEIARLRLEKDTIKNQNLE--K--KYLKDFE 3 ( 310) SENKQ-PQD--SQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLR--KEKKYIQEIK 4 ( 753) MKKSHDAII--DDLNRKLLDVTQKYTEKKLEMEKLLLENDSLS-------KDVSRLETVF 5 ( 903) LKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA // 0 ( 953) IVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVE 1 ( 159) AVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEME 2 ( 395) IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 3 ( 365) SITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVE 4 ( 804) VPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVK 5 ( 963) VQGQMDEDVQKVLKQ............................................. // 0 ( 1013) SYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLF 1 ( 219) SYRCRLAAAVRDCDQSQTA-RDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLS 2 ( 455) SYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQLS 3 ( 425) SLHSSLATAINEYNEI-VERKDLELVLWRA-DDVSR-HEKMGSNISQLTDKNELLTEQVH 4 ( 864) T-HEEVKMTLND--TLAKTNRELL-------DVKKKFED-INQEFVKIKDKNEILKRNLE 5 ( -) ............................................................ // 0 ( 1073) KTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIG 1 ( 278) NAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIA 2 ( 508) KAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIE 3 ( 482) KARVKFNTLKGKLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIG 4 ( 913) NTQNQIKAEYI-------SLAEH----EAKMSSLSQS---MRKVQDS--NAEILANYRKG 5 ( -) ............................................................ // 0 ( 1133) KQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQA-ESEKQS 1 ( 338) KQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQA-ESEKQI 2 ( 568) KQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQA-ECRKHR 3 ( 542) KQNSLEERIRQQELENLLLERQLEDARKEGDNKE-IVINIHRDC--------L-ENGKED 4 ( 957) QEEIVT-----LHAEIKAQKKELDTIQECIKVKYAPIVS----FEECERKFKATEKELKD 5 ( -) ............................................................ // 0 ( 1192) LLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVT- 1 ( 397) LSLQEKNKELMDEYNHLKERMDQCEKEKAGRKI--------------------------- 2 ( 623) LLLEEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDAS- 3 ( 592) LL-EERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISESPLEGT- 4 ( 1008) QLSEQTQKYSVSEEEVKKNKQ---ENDKLKKEIFT--LQKDLRD---KTVLIEKSHEMER 5 ( -) ............................................................ // 0 ( 1251) --SRYRINLEDETQDLKKKLGQIRN---QLQEAQDRHTEAVRCAEKM-QDHKQKLEKDNA 1 ( -) ------------------------------------------------------------ 2 ( 682) --SRHCTYLENGMQDSRKKLDQMRS---QV.............................. 3 ( 650) --SHCHINL-NETWTSKKKLFQV------------------------------------- 4 ( 1060) ALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEA 5 ( -) ............................................................ // 0 ( 1305) KLKVTVKKQMDKIEELQKNLLNANLSEDEK-EQLKKLMELKQSLECNLDQEMKKNVELER 1 ( -) ------------------------------------------------------------ 2 ( -) ............................................................ 3 ( 670) --------------EIQP--------EEKH-EEFRKLFELISLLNYTADQIRKKNRELEE 4 ( 1120) -LKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEK 5 ( -) ............................................................ // 0 ( 1364) EITGFKNLLKM----TRKKLNEYENGEFSFHGD---LKTSQFEMDIQINKLKHKIDDLTA 1 ( 430) --------------------------------------------------------DLTE 2 ( -) ............................................................ 3 ( 707) EATGYKKCLEM----TINMLNAFANEDFNCHGD---LNTDQLKMDILFKKLKQKFNDLVA 4 ( 1179) EVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLET 5 ( -) ............................................................ // 0 ( 1417) ELETAGSKCLHLDTKNQILQ--EELLSMKTVQKKCEKLQKNKKKL-----EQEVINLRSH 1 ( 434) AQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQL-----KQEVVNLKSY 2 ( -) ............................................................ 3 ( 760) EKEAVSSECVNLAKDNEVLH--QELLSMRNVQEKCEKLEKDKKML-----EEEVLNLKTH 4 ( 1239) QISSLNEKLANLNRKYEEVC--EEVLHA----KKKEISAKDEKELLHFSIEQEI---KDQ 5 ( -) ............................................................ // 0 ( 1470) IERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAA-SQ--ENLEQFRENNFAS 1 ( 489) MERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSH--EQLVQLREDNTTS 2 ( -) ............................................................ 3 ( 813) MEKDMVELGKLQEYKSELDERAVQEI-EKLEEIHL--QKQAE-YE--KQLEQLNKDNTAS 4 ( 1290) KERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERL-KQALNGLSQLTYTSGNP 5 ( -) ............................................................ // 0 ( 1527) MKSQMEL------RIKDLESELSKIKTSQED---FNKTELEKYKQLYLEELKVRKSLSSK 1 ( 547) IKTQMEL------TIKDLESEISRIKTSQAD---FNKTELERYKELYLEEVKVRESLSNE 2 ( -) ............................................................ 3 ( 867) LKKK-EL------TLKDVECKFSKMKTAYEE---VT-TELEEFKEVFAAAVKANNSMSKK 4 ( 1349) TKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDE.......... 5 ( -) ............................................................ // 0 ( 1578) LTKTNERLAEVNTKLLVEKQQ--SRSLFTTLTTRPVMEPPCVGNLNNSLDLNRKLIPREN 1 ( 598) LSRTNEMIAEVSTQLTVEKEQTRSRSLF................................ 2 ( -) ............................................................ 3 ( 916) LMKSDKKIAVISTKLFTEKQR--MKYFLSTLPTRPEPELPCVENLN-SIELNRKYIPKTA 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1636) LVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASPLGSTDESNLNQ 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 973) IRIPTSNPQTSNNC-KNFLTEV...................................... 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1696) DLVWKASREYVQVLKKNYMI 1 ( -) .................... 2 ( -) .................... 3 ( -) .................... 4 ( -) .................... 5 ( -) .................... //