# 0 KIAA1395, 2051 aa # 1 KIAA1771 (1302 aa) # 2 KIAA1058 (2095 aa) # 3 KIAA0716 (1388 aa) # 4 KIAA0209 (1842 aa) // exp sw-scr id% from to 1 0 5661 66.3 1 1302 2 9.8e-32 2674 30.6 311 2094 3 3.1e-07 249 22.4 723 1069 4 1.1e-05 226 24.7 1292 1584 // 0 ( 1) DARTMAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDF 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 61) EDVLLSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQVRAAVEMY 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 121) IEDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGS 1 ( -) ............................................................ 2 ( 311) ..................................................EAAMQEKRNG 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 181) GSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALLTLYP 1 ( -) ............................................................ 2 ( 321) DSHEDDEQSKLEGSGSGL-----DSYLPELAKSAREAEIKLKSESRVK--------LFYL 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 241) APDEDEAVERCSRPEPP--REHFGQRILVKCLSLKFEIE-------------IEPIFGIL 1 ( -) ............................................................ 2 ( 368) DPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTL 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 286) ALYDVREKKKISENFYFDLNSDSMKGLLRA------HGT-----------HPAISTLARS 1 ( -) ............................................................ 2 ( 428) SLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQ 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 329) AIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLEKLRLAAEQFC 1 ( -) ............................................................ 2 ( 488) GIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPYM--KSSDSSKVAQKVLK---NAKQAC 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 389) TRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQDRASSGDDAC 1 ( -) ............................................................ 2 ( 542) QRLGQYRMPFAWAARTLFK--DASGNLDKNA----------------------------- 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 449) SFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAP 1 ( -) ............................................................ 2 ( 571) RFSAI----------YRQDSNKLSNDDMLKLLADFRKPEKMAK-LPVILGNLDITIDNVS 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 509) EN-PHFCLSPELLHIKPYPDPRGRP-TKEILEF-PAREVYA-PHTSYRNLLYVYPHSLNF 1 ( -) ............................................................ 2 ( 620) SDFPNY-VNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKY 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 565) SSRQG--SVRNLAVRVQYM-TGEDPSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYE 1 ( -) ............................................................ 2 ( 679) DSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYD 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 622) EFKLHLPACVTENHHLLFTFYHVSCQ-PRPGTA-----LETPVGFTWIPLLQHRRLRTGP 1 ( -) ............................................................ 2 ( 739) EIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSE 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 676) FCLPVSVDQPPP--SYSVLTPDVAL-PGMRWVDGHKGVFSVELTAVSSVHPQDPYLDKFF 1 ( -) ............................................................ 2 ( 799) QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFF 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 733) TLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVI 1 ( -) ............................................................ 2 ( 859) QYCQKTESGAQAL---------GN---ELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLT 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 793) RPPIISGQI-VNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAFRLPGTEP 1 ( 1) .............................KNLEGNHDQHGRNSLLASYIHYVFRLPNTYP 2 ( 907) RA--TQEEVAVNVTR----VIIHVVAQCHE--------EGLESHLRSYVKYAYK---AEP 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 852) SLPDGAPPV---TVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEVSRILA 1 ( 32) NSSSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIG 2 ( 950) YV------------------------ASEY------------------KTVHEELTKSMT 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 909) SK---------------------------------------------------------- 1 ( 92) SKGLDRSNSWVNTGGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLP 2 ( 968) TI---------------------------------------------------------- 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 911) ---LLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRFPGR 1 ( 152) TKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPER 2 ( 970) ---L---KPSADFLTSNK-----LLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPAS 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 968) FLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAHYKQ 1 ( 212) FMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQ 2 ( 1019) YHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISC 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1028) VATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSST 1 ( 272) VSSKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSG 2 ( 1079) FAP-----GDPKTLFEYKFEFLRVVCNHEHYIPLNLPM-PFGK------------GRIQR 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1088) FSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVHSLL 1 ( 332) FSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLL 2 ( 1121) YQDLQLD------YSLTDEFCRNHFLVGLLLREVGTALQEFREVRLI----AISVLKNLL 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1148) CGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLH--DFAEGP---GQRSRLASM--- 1 ( 392) SSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLY--DFTETH---NQRGRPICI--- 2 ( 1171) IKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESLALP 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1200) ----LDSDTEG-------EGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCA 1 ( 444) ----ATDDYES-------ES--GSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTT 2 ( 1231) AVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGNS 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1249) LSAESS------------------------------RTLLACVLWVLKN-TEPALLQRWA 1 ( 491) FSAESS------------------------------RSLLICLLWVLKN-ADETVLQKWF 2 ( 1291) LPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYW- 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1278) TDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQ 1 ( 520) TDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQ 2 ( 1350) NKASTSELMDFFTISEVCLHQFQYMGKRYIARTGM--------MHARLQQ--LGSLD--- 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1338) EMVRRSR---ERSP----FGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALVEGNLAT 1 ( 580) EMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLAT 2 ( 1397) ----------------------NSLTFNHSYGH----SDA------DVLHQSLLEANIAT 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1391) EASLVVLDTLEIIV----QTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQRA 1 ( 640) EANLIILDTLEIVV----QTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRA 2 ( 1425) EVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRS 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1447) LVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIG--HNFA 1 ( 696) LVSKFPELLFEEETEQCADLCLRLLRHCSSSIGTIRSHASASLYLLMRQNFEIG--NNFA 2 ( 1485) LIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFV 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1505) RVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHM 1 ( 754) RVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHM 2 ( 1545) RTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRT 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1565) ILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCM 1 ( 814) ILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCL 2 ( 1605) VLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCY 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1625) VHAAALVAEYLALLE---------DHRHLPV-----------GCVSFQNISSNVLEESAI 1 ( 874) VHSAALVAEYLSMLE---------DRKYLPV-----------GCVTFQNISSNVLEESAV 2 ( 1665) VHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASM 3 ( -) ............................................................ 4 ( -) ............................................................ // 0 ( 1665) SDDILSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAH-RD 1 ( 914) SDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEAN-RD 2 ( 1725) MEDVGMQDV-------HFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKR-RD 3 ( 723) .................................FDRGKCWENGIILCRKIAEQYESY-YD 4 ( 1292) .........................LYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFD // 0 ( 1724) YKKLAAV---HGKLQEA--FTKIMHQSSGWERVFGTYFRVGFYG---------------A 1 ( 973) AKKLSTI---HGKLQEA--FSKIVHQSTGWERMFGTYFRVGFYG---------------T 2 ( 1777) FERLAHL---YDTLHRA--YSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEG 3 ( 749) YRNLSKM-----RMMEASLYDKIMDQ----QRLEPEFFRVGFYG---------------K 4 ( 1327) YELLSQNLIQQAKFYES--IMKIL-------RPKPDYFAVGYYG---------------Q // 0 ( 1764) HFGD-LDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKA 1 ( 1013) KFGD-LDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKA 2 ( 1832) FFED-EDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYA 3 ( 785) KFPFFLRNKEFVCRGHDYERLEAFQQRM----LNEFPHAIA--MQHANQPDETIFQAEAQ 4 ( 1363) GFPSFLRNKVFIYRGKEYERREDFQMQLMTQFP-----NAEKMNTTSAPGDDVK-NAPGQ // 0 ( 1823) YIQITYVEPYFDTYE------L------KDRVTYFDRNYGLRTFLFCTPF---TPDGR-A 1 ( 1072) YIQITYVEPYFDTYE------M------KDRITYFDKNYNLRRFMYCTPF---TLDGR-A 2 ( 1891) YIQVTHVIPFFDEKE------L------QERKTEFERSHNIRRFMFEMPF---TQTGK-R 3 ( 839) YLQIYAVTPIPESQE------VLQREGVPDNIKSFYKVNHIWKFRYDRPF---HKGTKDK 4 ( 1417) YIQCFTVQPVLDEHPRFKNKPV------PDQIINFYKSNYVQRFHYSRPVRRGTVD---P // 0 ( 1867) HGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQ 1 ( 1116) HGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQ 2 ( 1935) QGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSS 3 ( 890) ENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQ 4 ( 1468) ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQ // 0 ( 1927) ----DPPDAKM----LQMVLQGSVGPTVNQGPLEVAQVFLAE--I-----PEDPKLFRH- 1 ( 1176) ----DPADPKM----LQMVLQGSVGTTVNQGPLEVAQVFLSE--I-----PSDPKLFRH- 2 ( 1995) ----AEVDMIK----LQLKLQGSVSVQVNAGPLAYARAFL-----------DDTNTKRYP 3 ( 950) CQTRQMQNINP----LTMCLNGVIDAAVNGGVSRYQEAFFVKEYI-----LSHPEDGEK- 4 ( 1528) ----YQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTE--EYVRDHPEDQDKLTH- // 0 ( 1971) HNKLRL---CFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLP 1 ( 1220) HNKLRL---CFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIP 2 ( 2036) DNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQL- 3 ( 1000) IARLRE---LMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMKSSLG---IQEFS 4 ( 1581) LKDL-----................................................... // 0 ( 2028) QLMAPTPPGL--RNSLNRASFRKADL 1 ( 1277) QLYKAVLPVTCHRDSFSRMSLRKMDL 2 ( -) -......................... 3 ( 1054) ACMQASPVHF--PNGSPR........ 4 ( -) .......................... //