# 0 KIAA0666, 1085 aa # 1 KIAA0381 (1114 aa) # 2 KIAA2014 (1032 aa) # 3 KIAA1902 (1112 aa) # 4 KIAA1727 (1130 aa) // exp sw-scr id% from to 1 1.3e-66 4857 67.7 47 1114 2 4.8e-14 1148 26.8 31 1005 3 1.3e-12 1259 27.1 31 1111 4 3e-09 664 26.9 8 472 // 0 ( 1) EIEQNSAMAPRKRGGRGISFIFCCFRNNDHPEITYRLRNDSNFALQTMEPALPMPPVEEL 1 ( 47) .......MAPRKRSHHGLGFL-CCFGGSDIPEINLR----DNHPLQFMEFSSPIPNAEEL 2 ( 31) ...................................................MPMPEPCEL 3 ( 31) ........................................TDFRAHNVPLKLPMPEPGEL 4 ( -) ............................................................ // 0 ( 61) DVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEE-NKGATSWPEFYIDQLNS 1 ( 95) NIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINS 2 ( 40) EERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVK-NP-----PHTYIQKLQS 3 ( 51) EERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVK-NP-----PHTYIQKLKG 4 ( -) ............................................................ // 0 ( 120) MAARKSLLALEKEEEEERSKTIESLKTALRTKPMRFVTRFIDLD--GLSCILNFLK---- 1 ( 155) MAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIELE--GLTCLLNFLR---- 2 ( 94) FLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQC 3 ( 105) YLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQY 4 ( -) ............................................................ // 0 ( 174) --TMDYETSES-------RI----------------------------------HTSL-- 1 ( 209) --SMDHATCES-------RI----------------------------------HTSL-- 2 ( 154) SVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTL-- 3 ( 165) AVTFDFESVES-------TV----------------------------------ESSVDK 4 ( -) ............................................................ // 0 ( 189) --------------------IG-------------------------------------- 1 ( 224) --------------------IG-------------------------------------- 2 ( 212) --------------------PGRRALKNSRLVSQKDDVHVCIL----------------- 3 ( 184) SKPWSRSIEDLHRGSNLPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVC 4 ( -) ............................................................ // 0 ( 191) --CIKALMNNSQGRAHVLAHSESINVIAQSLSTENIKTKVAVLEILGAVCLVPGGHKKVL 1 ( 226) --CIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVL 2 ( 235) --CLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL 3 ( 244) IMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL 4 ( -) ............................................................ // 0 ( 249) QAMLHYQKYASERTRFQTLINDLDKSTGRYRD-E-VSLKTAIMSFINAVLSQGAGVESLD 1 ( 284) QAMLHYQVYAAERTRFQTLLNELDRSLGRYRD-E-VNLKTAIMSFINAVLNAGAGEDNLE 2 ( 293) AAFDNFKEVCKELHRFEKLMEYF-----RNEDSN-IDFMVACMQFINIVVH---SVEDMN 3 ( 304) SAFDNFKEVCGEKQRFEKLMEHF-----RNED-NNIDFMVASMQFINIVVH---SVEDMN 4 ( -) ............................................................ // 0 ( 307) FRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDELEFAKRFELVHIDTKS 1 ( 342) FRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKS 2 ( 344) FRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ-------------------AYLD--N 3 ( 355) FRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAY--LDNV----FDVGALLEDAETKN 4 ( -) ............................................................ // 0 ( 367) ATQMFELTRKRLTHSEAYPHFMSILHHCLQMPYKRSGNTVQYWLLLDRIIQQIVIQNDKG 1 ( 402) ASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERG 2 ( 383) VFDVGGLLEDAETKNVALEKVEELEEHVSHLTEK----------LLD------------- 3 ( 409) AA---------LERVEELEENISHLSEKLQDTENEAMSKIVE-------LEKQLMQRNKE 4 ( -) ............................................................ // 0 ( 427) QDPDSTPLENFNIK-NVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQ 1 ( 462) VDPDLAPLENFNVK-NIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTL 2 ( 420) -------LENENMM-RVAEL---EKQLLQREKELESIKETYENTSHQVHTLRRL----IK 3 ( 453) LDVVREIYKDANTQVHTLRKMV--------KEKEEAIQRQ-STLEKKIHELEKQGTIKIQ 4 ( -) ............................................................ // 0 ( 486) EKEE----MMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLHELSRRAVCASIPGGPSPG 1 ( 521) EKEE----MMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPV-------SSPP 2 ( 465) EKEE----AFQRRCHLEPNVRGLESVDSEALARVG--PAELSE-------GMPPSDLDLL 3 ( 504) KKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMG-----------AASSGPLPPPPPPL 4 ( 8) .........................................................APG // 0 ( 542) APGGPFP--SSVP-GSLLPP-PPPPPLPGGML-----PPPPPP-LPPGGPPPP-PGP--- 1 ( 570) PPGGPLTLSSSMT-TNDLPP-PPPP-LPFACC-----PPPPPPPLPPGGPPTP-PGA--- 2 ( 512) APAPPPE--EVLP----LPP-PPAPPLP----------PPPPP-LPDKCPPAP-PLP--- 3 ( 553) PPSSDTP--ETVQNGPVTPPMPPPPPPP---------PPPPPP-PPPPPPPPPLPGPASE 4 ( 11) FMIGQTP--PPAP-PP--PP-PPPPPSPPCSCSREECPSSPPP--PP--PPPL-PGE--- // 0 ( 588) ----PP-LGAIMP--PP----GAPM-----GLALKKKSIPQPTN-A---LKSFNWSKLPE 1 ( 618) ----PPCLGMGLP--LP----QDPYPSS--DVPLRKKRVPQPSH-P---LKSFNWVKLNE 2 ( 550) --------GA-----AP----SVVL-----TVGLSAIRIKKPIK-TKFRLPVFNWTALKP 3 ( 601) TVPAPP-LAPPLPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFR---MPVFNWVALKP 4 ( 57) ----PP-IPP--P--PP----GLPP-----TTHMNGYSHLGKKK-R---MRSFFWKTIPE // 0 ( 628) NKLEG--TVWTEIDDTKVFKILDLEDLERTFS--AYQRQQDFFVN-SNSKQKEADAIDDT 1 ( 662) ERVPG--TVWNEIDDMQVFRILDLEDFEKMFS--AYQRHQ-----------KELGSTEDI 2 ( 587) NQISG--TVFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICS-KNKTAQKA------ 3 ( 657) NQING--TVFNEIDDERILEDLNVDEFEEIFK--T--KAQGPAIDLSSSKQK----IPQK 4 ( 95) EQVRGKTNIWTLAARQEHHYQIDTKTIEELFG-----QQED--TT-KSSLPRRGRTLNSS // 0 ( 683) LSSKLKVKELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFV 1 ( 707) YLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFI 2 ( 638) -ASKV-----TLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT-LPVDFVECLMRFL 3 ( 707) GSNKV-----TLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKT-LPVDFVECLMRFL 4 ( 147) F--REAREEITILDAKRSMNIGIFLKQFKKSPRSIVEDI-HQGKSEHYGSETLREFLKFL // 0 ( 743) PEKSDIDLL---EEHKHE---LDRMAKADRFLFEMSRINHYQQRLQSLYFKKKFAERVAE 1 ( 767) PEKSDIDLL---EEHKHE---IERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAE 2 ( 691) PTEAEVKLL---RQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQM 3 ( 761) PTENEVKVLRLYERERKP---LENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQM 4 ( 204) PESEEVKKL---KAFSGD---VSKLSLADSFLYGLIQVPNYSLRIEAMVLKKEFLPSCSS // 0 ( 797) VKPKVEAIRSGSEEVFRSGALKQLLEVVLAFGNYMNKGQR-GNAYGFKISSLNKIADTKS 1 ( 821) AKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQR-GGAYGFRVASLNKIADTKS 2 ( 748) LTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKR-GAVYGFKLQSLDLLLDTKS 3 ( 818) LTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKR-GAVYGFKLQSLDLLLDTKS 4 ( 258) LYTDITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGYAGNAVGFKLSSLLKLADTKA // 0 ( 856) SIDKNITLLHYLITIVENKYPSVLNLNEELRDIPQAAKVNMTELDKEISTLRSGLKAVET 1 ( 880) SIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEV 2 ( 807) T-DRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRR 3 ( 877) T-DRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKR 4 ( 318) N-KPGMNLLHFVAQEAQKKDTILLNFSEKLHHVQKTARLSLENTEAELHLLFVRTKSLKE // 0 ( 916) ELEYQKSQPPQPGDKFVSVVSQFITVASFSFSDVEDLLAEAKDLFTKAVKHFGEEAGKIQ 1 ( 940) ELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQ 2 ( 866) ECSIHDN----------SVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTP 3 ( 936) EYTMHDHN---------TLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTP 4 ( 377) NI--------QRDGELCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFFCEDKKTMK // 0 ( 976) PDEFFGIFDQFLQAVSEAKQENENMRKKKEEE------ERRA-------RMEAQ------ 1 ( 1000) PDEFFGIFDTFLQAFSEARQDLEAMRRRKEEE------ERRA-------RMEAM------ 2 ( 916) PSVFFPVFVRFIRSYKEAEQENEA-RKKQEEV------MREKQLAQEAKKLDAK------ 3 ( 987) PSVFFPVFVRFVKAYKQAEEENE-LRKKQEQALMEKLLEQEA-------LMEQQDPKSPS 4 ( 429) LDECFQIFRDFCTKFNKAVKDNHD------RE------AQEL-------RQLQR------ // 0 ( 1017) LKEQRER--------ERKMRKAK-----ENSE----ESGEFDDLVSALRSGEVFDKDLSK 1 ( 1041) LKEQRER--------ERWQRQRKVLAAGSSLE----EGGEFDDLVSALRSGEVFDKDLCK 2 ( 963) TPSQRNKWQQQELIAELRRRQAK-----EHRPVYEGKDGTIEDIITGL............ 3 ( 1039) HKSKRQQQELIA---ELRRRQVK-----DNRHVYEGKDGAIEDIITDLRNQPYRRADAVR 4 ( 464) LKEQEQK--------QR---------.................................. // 0 ( 1060) LKRNRKRITNQMTDSSRERPITKLNF 1 ( 1089) LKRSRKRSGSQALEVTRERAINRLNY 2 ( -) .......................... 3 ( 1091) -RSVRRRFDDQNLRSVNGAEIT.... 4 ( -) .......................... //