# 0 KIAA0715, 1498 aa # 1 KIAA0566 (1163 aa) # 2 KIAA1487 (650 aa) # 3 KIAA1939 (1082 aa) # 4 KIAA1137 (933 aa) # 5 KIAA1021 (1102 aa) // exp sw-scr id% from to 1 7.3e-128 3205 50.3 1 1046 2 9e-122 2347 57.7 1 575 3 4.8e-59 1921 31.4 17 1082 4 4.6e-58 1552 31.9 1 853 5 5.8e-54 1816 32.1 9 1057 // 0 ( 1) HSPVTSWTNFLGKNLSHLFYLSLSFEIPATDLRLLLEMALSVDSSWHRWQWRVRDGFPHC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) PSETTPLLSPEKGRQSYNLTQQRVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLP 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 9) ......................................IPQRYPDNRIVSSKYTFWNFIP // 0 ( 121) RNLFEQFHRWANLYFLFLVILNWM---PSMEVFHREITMLPLAIVLFVIMIKDGMEDFKR 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 31) KNLFEQFRRVANFYFLIIFLVQLIIDTPTSPV----TSGLPLFFVITVTAIKQGYEDWLR // 0 ( 178) HRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGIC 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 17) ..........................WMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLC 4 ( -) ............................................................ 5 ( 87) HKADNAMNQCPVHFIQHGK--LVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTC // 0 ( 238) HLETASLDGETNLKQRRVV---KGFSQQEVQFEPEL-FHNTIVCEKPNNHLNKFKG---- 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 51) YVETAELDGETNLKVRHAL---SVTSELGADISRLAGFDGIVVCEVPNNKLDKFMG---- 4 ( -) ............................................................ 5 ( 145) HVTTASLDGESSHKTHYAVQDTKGFHTEE---DIGG-LHATIECEQPQPDLYKFVGRINV // 0 ( 290) YMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSG-PRYKRSKIER 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( 104) ILSWKD-SKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK-TKFKRTSIDR 4 ( 1) ..............................................NSGRTKFKRTSIDR 5 ( 201) YSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQS-KSQKRSAVEK // 0 ( 349) RMN--IDIFFCIGILILMCLIGAVGHSIWNG-T----FEEHPPFDVPDANGSFLPSALGG 1 ( 1) ......................................EKKSLFYVPKSDGSSLSPVTAA 2 ( -) ............................................................ 3 ( 162) LMN--TLVLWIFGFLICLGIILAIGNSIWESQT----GDQFRTFLF--WNEGEKSSVFSG 4 ( 15) LMN--TLVLWIFGFLVCMGVILAIGNAIWEH-EVGMRFQVYLPWD-EAVDSAFF----SG 5 ( 260) SMNAFLIVYLCI--LISKALINTVLKYVWQS-EP---FRDEPWYNQKTESERQRNLFLKA // 0 ( 402) FYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDL 1 ( 23) VYSFLTMIIVLQVLIPISLYVSIEIVKACRVYFINQDMQLYDEETDSQLQCRALNITEDL 2 ( -) ............................................................ 3 ( 214) FLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEEL 4 ( 67) FLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEEL 5 ( 314) FTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEEL // 0 ( 462) GQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLS 1 ( 83) GQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVP-RGGS 2 ( -) ............................................................ 3 ( 274) GQIEYIFSDKTGTLTQNIMTFKRCSINGRIYG--------EVHDDLDQKTEITQEKEPVD 4 ( 127) GQVEYIFSDKTGTLTQNIMVFNKCSINGHSY------------------GDVFD------ 5 ( 374) GQVEYIFTDKTGTLTENNMEFKECCIEGHVY----------VPHVI-----------C-- // 0 ( 522) FSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYR--QRSMGHRESS-QPPVAFSSSIE 1 ( 142) VSQR-----GSIGSHQSVRVVHRTQSTK----SHRRTGSRAEAKRASMLSKHTAFSSPME 2 ( -) ............................................................ 3 ( 326) FSVK-------------------SQADR-----------------------EFQFF---- 4 ( 163) ------------------------------VLGH----KAELGERP----EPVDFSF--- 5 ( 411) ----------------NGQVL-----------------------------PE---SSGID // 0 ( 579) KDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTT-SSIADFFLALTICNSVMVSTTTE 1 ( 193) KDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQ 2 ( -) ............................................................ 3 ( 340) -----DHHLMESIK--------MGDPK------------VHEFLRLLALCHTVM------ 4 ( 182) -NPLADKKFL--FWDPSL-LEAVKIGDP----------HTHEFFRLLSLCHTVM------ 5 ( 423) ----------------------MIDSSP---SVNGR-EREELFFRALCLCHTVQV----- // 0 ( 638) PRQRVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDS 1 ( 253) PRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSS--HKLGSSFPSTPS 2 ( -) ............................................................ 3 ( 369) -----------------------------------------------------------S 4 ( 222) -----------------------------------------------------------S 5 ( -) ------------------------------------------------------------ // 0 ( 698) DE----RDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFC 1 ( 311) SDGMLLRLEERLGQPTSAIASNGYSS----QADNWAS------ELAQEQE----SERELR 2 ( -) ............................................................ 3 ( 370) EE----N------SAG-----------------------------------------ELI 4 ( 223) EE----KNEG-----------------------------------------------ELY 5 ( 452) ------KDDDSV-DGPRKSPDGG-KSCV-------------------------------- // 0 ( 754) YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 1 ( 357) YEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRMSVV 2 ( 1) ......................................................KRMSVV 3 ( 379) YQVQSPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRMSVI 4 ( 232) YKAQSPDEGALVTAARNFGFVFRSRTPKTITVH-EMGTAITYQLLAILDFNNIRKRMSVI 5 ( 472) YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVI // 0 ( 814) VRHPLTGEIVVYTKGADSVIMDLLEDPACVPD-INMEKKLRKIRARTQKHLDLYARDGLR 1 ( 417) IRHPLTDEINVYTKGADSVVMDLLQ-PCSSVD-ARGRHQ-KKIRSKTQNYLNVYAAEGLR 2 ( 7) VRHPLSNQVVVYTKGADSVIMELLS--VASPDGASLEKQQMIVREKTQKHLDDYAKQGLR 3 ( 438) VRNP-EGQIKLYSKGADTILFEKLH-----PS-NEVLLSL------TSDHLSEFAGEGLR 4 ( 291) VRNP-EGKIRLYCKGADTILLDRLH------------HSTQELLNTTMDHLNEYAGEGLR 5 ( 532) VKSA-TGEIYLFCKGADSSIF---------PR-V-IEGKVDQIRARVERN----AVEGLR // 0 ( 873) TLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQE 1 ( 474) TLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQD 2 ( 65) TLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQE 3 ( 485) TLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAELYEEIERDLMLLGATAVEDKLQE 4 ( 338) TLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQ 5 ( 576) TLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQE // 0 ( 933) GVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLL-NQTDT-VYTINTENQETCESIL 1 ( 534) GVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLL-DHDEE-VITLNATSQEACAALL 2 ( 125) GVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLL-EPDDK-LFILNTQSKDACGMLM 3 ( 545) GVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMND-VFVIAGNNAVEVREEL 4 ( 398) GVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKML-TDDMTEVFIV------TGHTVL 5 ( 636) KAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLF-RRNTQ-LLELTTKRIE--EQSL // 0 ( 991) NCALEEL-KQFRE-LQKPDRKLF-G---FRLPSKTPS--ITS--EAVVPEAGLVIDGKTL 1 ( 592) DQCLCYV--QSRG-LQRAPEKTK-GKVSMRFSSLCPP--STS--TASGRRPSLVIDGRSL 2 ( 183) STILKEL-QK-KT-QALPEQVSL-S---EDLLQ--PP--VPR--DSGL-RAGLIITGKTL 3 ( 604) RKAKQNLFGQNRN-FSN-GHVVC-E---KKQQLELDS--IVE--ETITGDYALIINGHSL 4 ( 451) E-VREEL-RKAREKMMDSSRSVGNG---FTYQDKLSSSKLTSVLEAVAGEYALVINGHSL 5 ( 692) HDVL------F-E-LSKTVLRHS-G---SLTRDNLSG--LSA--D--MQDYGLIIDGAAL // 0 ( 1041) NAIFQ-------GKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVR-DKLRVMTLSIGD 1 ( 644) AYALE-------KNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVR-SKLKAMTLAIGD 2 ( 229) EFALQ-------ESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVR-SHLQVMTLAIGD 3 ( 654) AHALE-------SDVKNDLLELACMCKTVICCRVTPLQKAQVVELVK-KYRNAVTLAIGD 4 ( 506) AHALE-------ADMELEFLETACACKAVICCRVTPLQKAQVVELVK-KYKKAVTLAIGD 5 ( 734) SLIMKPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGD // 0 ( 1093) GANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVY 1 ( 696) GANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLY 2 ( 281) GANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILY 3 ( 706) GANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCY 4 ( 558) EANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCY 5 ( 794) GANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQY // 0 ( 1153) YLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLL 1 ( 756) FFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLL 2 ( 341) FFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLM 3 ( 766) FFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSV 4 ( 618) FFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSM 5 ( 854) FFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLK // 0 ( 1213) ALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAY---K------GSD----I 1 ( 816) TNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAY---Y------DSN----V 2 ( 401) QLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTY---Q------GSD----T 3 ( 826) DCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVA------GEDGQHIA 4 ( 678) EYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVF---ADATRDDGTQ----L 5 ( 914) RDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVF---E------NTT----V // 0 ( 1260) ----DVF---TFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNAT 1 ( 863) ----DLF---TWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNAS 2 ( 448) ----DIF---AFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAM 3 ( 880) ----DYQ---SFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSN 4 ( 731) A---DYQ---SFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSN 5 ( 961) TSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGV // 0 ( 1313) CVICNSPTNPYWVMEGQ--LSNPTFYLVCFLTPVVALLP----RYFFLSLQGTCGKS--- 1 ( 916) CATCYPPSNPYWTMQAL--LGDPVFYLTCLMTPVAALLP----RLFFRSLQGRVFPT--- 2 ( 501) CVTCNPPSNPYWIMQEH--MLDPVFYLVCILTTSIALLP----RFVYRVLQGSLFPS--- 3 ( 933) GIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQ--- 4 ( 785) GLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRY 5 ( 1021) IWPFLNYQRMYYVFIQM--LSSGPAWLAIVLLVTISLLP..................... // 0 ( 1364) --L--ISKAQKIDK-----------------LPPDKRNLEIQSWRSRQRPAPVPEVARPT 1 ( 967) --Q--LQLARQLTRKSPRRCSAPKETFAQGRLPKDS-GTEHSSGRTVKTSVPLSQPSWHT 2 ( 552) --P--ILRAKHFDR-----------------LTPEERTKALKKWR............... 3 ( 990) --IRRWQKAQKKAR------------------PPSSR--RPRTRRSSSRRSGYAFAHQEG 4 ( 845) TQL--VRKKQK................................................. 5 ( -) ............................................................ // 0 ( 1403) HHPVSSITGQDFSASTPKSSNPPKRKHVEESVLHEQRCGTECMRDDSCSGDSSAQLSSGE 1 ( 1022) QQPVCSLEASGEPSTVDMSM--PVREH................................. 2 ( -) ............................................................ 3 ( 1028) YGELIT-SGKNMRAKNPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL.... 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1463) HLLGPNRIMAYSRGQTDMCRCSKRSSHRRSQSSLTI 1 ( -) .................................... 2 ( -) .................................... 3 ( -) .................................... 4 ( -) .................................... 5 ( -) .................................... //