# 0 KIAA0581, 1218 aa # 1 KIAA1516 (2304 aa) # 2 KIAA0450 (1182 aa) # 3 KIAA1092 (1154 aa) # 4 KIAA1069 (787 aa) # 5 KIAA1964 (757 aa) // exp sw-scr id% from to 1 3.6e-14 939 27.7 1346 2289 2 6.4e-14 1095 30.5 82 909 3 2e-12 1151 31.0 166 909 4 5.4e-11 930 30.5 13 673 5 7e-11 1066 30.9 117 755 // 0 ( 1) AQMAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIV-TPIILRTDPQGFF-FYWTD 1 ( -) ............................................................ 2 ( 82) ...........................................VKLRGGSKGLVRFYYLD 3 ( 166) ..................CI-NSMVEGSELKKVRSNSRIYHRYFLLDADMQSLR-WEPSK 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 59) QNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPD----LV 1 ( -) ............................................................ 2 ( 99) EHRSCIRW-----RPSRKNEKAKISID-SIQEVSE-GRQSEVFQRYPDGSFDPNCCFSIY 3 ( 206) KDSEKAKIDIKSIKEVRTGKNTDIFRSNGISDQIS-------EDCAFSVIYGE------- 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 115) NISH---LNLVAFQEEVAKEWTNEVFSLAT------NL-----L--AQNM-SRD----AF 1 ( -) ............................................................ 2 ( 152) HGSHRESLDLVSTSSEVARTWVTGLRYLMA------GISDEDSL--ARRQRTRD----QW 3 ( 252) NYES---LDLVANSADVANIWVTGLRYLISYGKHTLDM-----LESSQDN-MRT----SW 4 ( -) ............................................................ 5 ( 117) ...N---LDLAAPTAEEAQRWVRGLTKLRA------RLDA---M--SQRE-RLDHWIHSY // 0 ( 154) LEKAYTKLKLQVTPEGRIPLKNIY---RLF-----SADRKRVETALEACSLPSSRNDSIP 1 ( -) ............................................................ 2 ( 200) LKQTFDE--ADKNGDGSLSIGEVL---QLLHKLNVNLPRQRVKQMFRE----ADTDDH-- 3 ( 299) VSQMFSE--IDVDNLGHITLCNAVQCIRNL-----NPGLKTSKIELKFKELHKSK-DKAG 4 ( -) ............................................................ 5 ( 159) LHRADSN---QDSKMSFKEIKSLL---RMV-----NVDMNDMYAYLLFKECDHSNNDRLE // 0 ( 206) QEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILY 1 ( -) ............................................................ 2 ( 249) QGTLGFEEFCAFYKMMSTRRDLYLLMLTY-SNHKDHLDAASLQRFLQVEQK--------M 3 ( 351) TEVTKEEFIEVF-HELCTRPEIYFLLVQF-SSNKEFLDTKDLMMFLEAEQGVAHINE--- 4 ( 13) .................................KDHLTVEELAQFLKVEQK---MNNVT- 5 ( 208) GAEIEE-----FLRRLLKRPELEEIFHQYSGEDR-VLSAPELLEFLEDQGEE---GATL- // 0 ( 266) PPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLN-EDMSQPL 1 ( 1346) .....DEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPL 2 ( 300) AGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVH-QDMTQPL 3 ( 406) -----EISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVC-QDMKQPL 4 ( 36) ----TDYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVY-QDMDQPL 5 ( 258) -----ARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCVF-QDMNQPL // 0 ( 325) SHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTM 1 ( 1401) SYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGM--PIIYHGHTL 2 ( 359) SHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDG--PDGEPIVHHGYTL 3 ( 460) SHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDG--PDNEPVIYTGHTM 4 ( 91) CNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDG--PDGEPVVHHGYTL 5 ( 312) AHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGG--EPVIYHGHTL // 0 ( 385) TTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLE 1 ( 1459) TTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLP-QQRKMAEIFKTVFGEKLVTKFLF 2 ( 417) TSKILFKDVIETINKYAFIKNEYPVILSIENHC-SVIQQKKMAQYLTDILGDKL---DLS 3 ( 518) TSQIVFRSVIDIINKYAFFASEYPLILCLENHC-SIKQQKVMVQHMKKLLGDKLYTTS-- 4 ( 149) TSKILFRDVVETINKHAFVKNEFPVILSIENHC-SIQQQRKIAQYLKGIFGDKLDLSSVD 5 ( 370) TSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGL-EQQAAMARHLCTILGDMLVTQALD // 0 ( 445) K-YPLESGVPLPSPMDLMYKILVKNKK--------------------------------- 1 ( 1518) E-TDFSDDPMLPSPDQLRKKVLLKNKKL-------------------------------- 2 ( 473) S-VSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDDDCKLLNGD 3 ( 575) ---PNVEESYLPSPDVLKGKILIK------------------------------------ 4 ( 208) T-GECKQ---LPSPQSLKGKILVKGKK--------------------------------- 5 ( 429) SPNPEE----LPSPEQLKGRVLVKGKK--------------------------------- // 0 ( 471) --KSHKSSEGSGKKKLSEQAS---NT-YSD-------SSSMFE-PSSP----GAGEA--- 1 ( 1545) --KAHQTPVDILKQKAHQLASMQVQA-YNG-------GNANPR-PANN----EEEEDEED 2 ( 532) ASTNRKRVENTAKRKLDSLIK---ESKIRDCEDPNNFSVSTLS-PSGKLGRKSKAEE--- 3 ( 596) ------------AKKLSSNCS---GV-EGD-------VTDE-D-EGAE----MSQRM--- 4 ( 231) --LPYHLGDDAEEGEVSDEDS---AD-EIE-------DECKFKLHYSN----GTTEH--- 5 ( 452) --LPAARSEDG--RALSDR----------------------------------------- // 0 ( 510) ----DTES---------------DDD-------------------D-------------- 1 ( 1590) EYDYDYES---------------LSD-------------------DNILEDRPENKSCND 2 ( 585) ----DVES---------------GEDAGASRRNGRLVVGSFSRRKK-------------- 3 ( 624) ----GKEN---------------MEQ-------------------P-------------- 4 ( 271) ----QVESFIRKKLESLLKESQIRDK-------------------E-------------- 5 ( 467) ----EEEE---------------EDD-------------------E-------------- // 0 ( 518) -----------------DDDDCK----------------KS-S-----------MDEGTA 1 ( 1616) KLQFEYNEEIPKRIKKADNSACN----------------KG-KVYDMELGEEFYLDQNKK 2 ( 612) -----------------KGSKLK----------------KAAS-----------VEEGDE 3 ( 632) -----------------NNVPVK----------------RF-Q-----------L----- 4 ( 294) -----------------DPDSFTVRALLKATHEGLNAHLKQ-S-----------PDVKES 5 ( 475) -----------------EEEEEV----------------EA-A-----------AQRRLA // 0 ( 533) GSEAM------ATEE---------MSNLVNYIQPVKFESFEI----------SK------ 1 ( 1659) ESRQI------APE----------LSDLVIYCQAVKFPGLSTLNASGSSRGKER------ 2 ( 628) GQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEM------------------ 3 ( 642) ------------CKE---------LSELVSICKSVQFKEFQV----------SF------ 4 ( 325) GKKSH------GRSL---------MTNFGKHKKTTKSRSKSY----------STDDEEDT 5 ( 490) ---KQ------ISPE---------LSALAVYCHATRLRTLHP----------AP------ // 0 ( 562) ---------------KRNKSF-----------EMS------------------------S 1 ( 1697) ---------------KSRKSIFGNNPGRMSPGETA------------------------S 2 ( 670) ---------------EAASSW-----------QVS------------------------S 3 ( 665) ---------------QVQKYW-----------EVC------------------------S 4 ( 360) QQSTGKEGGQLYRLGRRRKTMKLCR-------ELSDLVVYTNSVAAQDIVDDGTTGNVLS 5 ( 516) ---------------NAPQPC-----------QVS------------------------S // 0 ( 572) FVET------KGLEQL---TKSPV-----------------------------------E 1 ( 1718) FNKTSGKSSCEGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQK 2 ( 680) FSET------KAHQIL---QQKPA-----------------------------------Q 3 ( 675) FNEV------LASKYA---NENPG-----------------------------------D 4 ( 413) FSET------RAHQVV---QQKSE-----------------------------------Q 5 ( 526) LSER------KAKKLI---REAGN-----------------------------------S // 0 ( 588) FVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGK 1 ( 1778) LTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGG 2 ( 696) YLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGG 3 ( 691) FVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGN 4 ( 429) FMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGN 5 ( 542) FVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQ // 0 ( 648) SGYRLKPEFMRRPD----KHFDPFTEGIVDGIVANTLSVKIISGQ--------FL----S 1 ( 1838) CGYVLKPPVLWDKNCPMYQKFSPL-ERDLDSMDPAVYSLTIVSGQ--------NV----C 2 ( 756) CGYVLKPGCMCQG------VFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSML----G 3 ( 751) CGYVLRPAIMREEV----SFFSANTKDSVPGVSPQLLHIKIISGQ--------NF----P 4 ( 489) CGYVLKPQQMCKGT------FNPFSGDPLPANPKKQLILKVISGQ--------QL----P 5 ( 602) CGYVLKPACLRQPD----STFDPE----YPGPPRTTLSIQVLTAQ--------QLPKLNA // 0 ( 692) ---DKK--------VGT-------Y-VEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEE 1 ( 1885) P--SNS--------MGS-------PCIEVDVLGMPLDSCH--FRTKPIHRNTLNPMWNEQ 2 ( 806) ---DRGEI------IDP-------F-VEVEIIGLPVDCSRE--QTRVVDDNGFNPTWEET 3 ( 795) ---KPKGSGAKGDVVDP-------Y-VYVEIHGIPADCAEQ--RTKTVHQNGDAPIFDES 4 ( 531) KPPDSM--------FGDRGEIIDPF-VEVEIIGLPVDCCKD--QTRVVDDNGFNPVWEET 5 ( 646) ---EKPHSI-----VDP-------L-VRIEIHGVPADCARQ--ETDYVLNNGFNPRWGQT // 0 ( 733) PIVFKKVVLPTLACLRIAVYEE---GGK----FI-GHRILPVQAIRPGYHYICLRNERNQ 1 ( 1926) -FLFR-VHFEDLVFLRFAVVEN---NSS----AVTAQRIIPLKALKRGYRHLQLRNLHNE 2 ( 847) -LVFM-VHMPEIALVRFLVWDHDPIGRD----FI-GQRTLAFSSMMPGYRHVYLEG---- 3 ( 842) -FEFQ-INLPELAMVRFVVLDDDYIGDE----FI-GQYTIPFECLQTGYRHVPLQSLTGE 4 ( 580) -LTFT-VHMPEIALVRFLVWDHDPIGRD----FV-GQRTVTFSSLVPGYRHVYL-----E 5 ( 688) -LQFQ-LRAPELALVRFVVEDY---DATSPNDFV-GQFTLPLSSLKQGYRHIHLLSKDGA // 0 ( 785) PLTLPAVFVYIEVKDYVPDTYADVIEALS--NPIRYVNLMEQR----------------- 1 ( 1977) VLEISSLF--INSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTI 2 ( 896) -MEEASIFVHVAVSD............................................. 3 ( 895) VLAHASLFVHVAITN............................................. 4 ( 628) GLTEASIFVHITINE-IYGKWSPLILNPS--YTILHF-LGATK----------------- 5 ( 742) SLSPATLFIQIRIQ.............................................. // 0 ( 826) -----AKQLAALTLEDEEEVKKEA------DPGETPSEAPSEARTTPAENGVNHTTTLTP 1 ( 2035) NGGTKAKQLLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIM- 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 667) -----NRQLQGL................................................ 5 ( -) ............................................................ // 0 ( 875) KPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKD 1 ( 2094) QILSSWFPEEGYMGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRT 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 935) LVKRHHKKTT-DLIKEHTTK----YNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGS 1 ( 2154) VIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKT--TTPKSSQ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 990) STIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLL--IQKLTDV 1 ( 2212) RVLLDQECVFQAQSKWK------GAGKFILKLK-EQVQASREDKKKGISFASELKKLTKS 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1048) AEECQN----NQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRS 1 ( 2265) TKQPRGLTSPSQLLTSESIQTKEEK................................... 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1104) YIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEI 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1164) LEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL 1 ( -) ....................................................... 2 ( -) ....................................................... 3 ( -) ....................................................... 4 ( -) ....................................................... 5 ( -) ....................................................... //