# 0 KIAA1728, 1644 aa # 1 KIAA1636 (1864 aa) # 2 KIAA1223 (1089 aa) # 3 KIAA1250 (1777 aa) # 4 KIAA0379 (1059 aa) # 5 KIAA1334 (989 aa) // exp sw-scr id% from to 1 9.4e-172 5574 52.4 47 1864 2 5e-15 799 25.9 1 1015 3 2.2e-08 508 30.0 23 411 4 9.8e-07 453 33.0 56 385 5 5.5e-06 322 29.7 32 249 // 0 ( 1) TLESKDSGIIATITSSSENDDRSGSSLEWNKDGSLRLGVQKGVLHDRRADNCSPVAEEET 1 ( 47) TLESRDSGIIATLTSYSENVERTKYAGESSKELGSGGNIKPWQSQKSSMDSCLYRVDENM 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) TGSAESTLPKAESSAGDGPVPYSQGSSSL-IMPRPNSVAATSSTKLEDLSYLDGQRNAPL 1 ( 107) TASTYS-LNKIPERNLETVLSQSVQSIPLYLMPRPNSVAATSSAHLEDLAYLDEQRHTPL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 120) RTSIRLPWHNTAGGRAQE-VKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQI 1 ( 166) RTSLRMPRQSMGGARTQQDLRVRFAPYRPPDISLKPLLFEVPSITTESVFVGRDWVFHEI 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 179) EENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPT 1 ( 226) DAQLQSSNASVNQGVVIVGNIGFGKTAIISRLVALSCHGTRMRQIASDSPHASPKHVDAN 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 239) QDLHFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYT 1 ( 286) REL---PLTQPPSAHSSITSGSCP-GT--PEMRRRQEEAMRRLASQVVAYHYCQADNAYT 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 299) CLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTN 1 ( 340) CLVPEFVHNVAALLCRSPQLTAYREQLLREPHLQSMLSLRSCVQDPMASFRRGVLEPLEN 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 359) LRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQE 1 ( 400) LHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTVRTSLQE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 419) IISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADATLIGKVSSH 1 ( 460) ITKLLPFHRIFLDRLEENEAIDQDLQAYILHRIHSSSEIQNNISLNGKMDNTTFGKLSSH 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 479) LVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERAL 1 ( 520) LKTLSQGSYLYLKLTFDLIEKGYLVLKSSSYKVVPVSLSEVYLLQCNMKFPTQSSFDRVM 2 ( 1) .................................................LFVRKQFAKVQ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 539) PILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHP 1 ( 580) PLLNVAVASLHPLTDEHIFQAINAGSIEGTLEWEDFQQRMENLSMFLIKRRDMTRMFVHP 2 ( 12) PILNVILAACRPLTITELYHAVWTKNMS--LTLEDFQRKLDILSKLLVDGLGNTKILFHY 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 599) SFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGL 1 ( 640) SFREWLIWREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIELGHHILKAHIFKGL 2 ( 70) SFAEWLL-DVKHCTQKYLCNAAEGHRMLAMSYTCQAKNLTPLEAQEFALHLINSNL---- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 659) SKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEV--- 1 ( 700) SKKVGVSSSILQGLWISYSTEGLSMALASLRNLYTPNIKVSRLLILGGANINYRTEV--- 2 ( 125) ----QLETAEL-ALWMIWN--G-TPVRDSLSTLIPKEQEVLQLLVKAGAHVNSEDDR--- 3 ( 23) ....................................NIPALKALLEKCKDVDERNEC--- 4 ( 56) .................................YLGDAEIIELLILSGARVNAKDSKWLT 5 ( -) ............................................................ // 0 ( 716) -LNNAPILC-VQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKK 1 ( 757) -LNNAPILC-VQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKK 2 ( 174) -TS-----CIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSR 3 ( 44) --GQTPLM--IAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKC 4 ( 83) PLHRAVASC-------SEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPL 5 ( -) ............................................................ // 0 ( 774) GVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPG-PPQPGTLRKSHALQQALTAAA 1 ( 815) RAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMA-GQQQGVFKKSHAIQQALIAAA 2 ( 228) GADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG--------WTALRSAA 3 ( 100) GVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANP-------SVTGLYSVYPIIWAAG 4 ( 136) LSNVNVSDRAGRTALHHAAFSGHGEMVKLLL----SRG-ANINAFDKKD---RRAIHWAA 5 ( 32) .......................................................LLQAV // 0 ( 833) SMGHSSVVQCLLGM-EK-EHEVE---VNGTDTLWGETALTAAAGRGKLEVCELLLGHGAA 1 ( 874) SMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETALTAAAGRGKLEVCRLLLEQGAA 2 ( 280) WGGHTEVVSALLYA------GVK---VDCADAD-SRTVLRAAAWGGHEDIVLNLLQHGAE 3 ( 153) R-GHADIVHLLL------QNGAK---VNCSDK-YGTTPLVWAARKGHLECVKHLLAMGAD 4 ( 188) YMGHIEVVKLLVS------HGAE---VTCKDKK-SYTPLHAAASSGMISVVKYLLDLGVD 5 ( 37) ENGDAEKVASLLGK-KG-ASATK---HDSE----GKTAFHLAAAKGHVECLRVMITHGVD // 0 ( 888) VSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAA-C----EGHLS 1 ( 934) VAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAA-S----EGHLG 2 ( 330) VNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHAS 3 ( 202) VDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIAS-K----EGHTE 4 ( 238) MNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAA-A----STHGA 5 ( 88) VTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAA-A----QGCLQ // 0 ( 943) T-VEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLA 1 ( 989) T-VDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLA 2 ( 390) V-VSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAA 3 ( 257) I-VQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWA 4 ( 293) LCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIA 5 ( 143) A-VQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLA // 0 ( 1002) AFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKG---AKL----- 1 ( 1048) AFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKG---AKI----- 2 ( 449) ASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHR----- 3 ( 316) VEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKG---AKVSAVDK 4 ( 353) ARYGHELLINTLITSGADTAKRGIHGMFPLHLA........................... 5 ( 202) CEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSK............ // 0 ( 1054) -GNAAWA---MAT-SKPDILIILLQKLMEEG---NVMYKKGKMKE--AAQRYQYALRKFP 1 ( 1100) -GPATWA---MAT-SKPDIMIILLSKLMEEG---DMFYKKGKVKE--AAQRYQYALKKFP 2 ( 504) -DDAGWTPLHMAA-FEGHRLIC--EALIEQGARTNEIDNDGRIPFILASQEGHYDCVQIL 3 ( 373) KGDTPLH---IAIRGRSRKLAELLLRNPKDG---RLLYRPNKAGE............... 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1104) REGFGE-DMRPFNELRVSLYLNLSRCRRKTND--FGMAEEFASKALELKPKSYEAFYARA 1 ( 1150) REGFGE-DLKTFRELKVSLLLNLSRCRRKMND--FGMAEEFATKALELKPKSYEAYYARA 2 ( 560) LENKSNIDQRGYDG-RNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLY------I 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1161) RAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLN 1 ( 1207) RAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQM----QQPQQPPPPPQPQ 2 ( 613) LALEN--QLTMAEYFLENGANVEASDAEGRTAL---HVSCWQGHMEMVQVLIA-YHADVN 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1221) DSENEEDTPTPGLSDHFHSEETEEEETSPQE-ESVS--------PT---PRSQ-PSSSVP 1 ( 1263) QQLPEEAEPEPQHEDIYSVQDIFEEEYLEQDVENVSIGLQTEARPSQGLPVIQSPPSSPP 2 ( 667) AADNEKRSALQSAAWQGHVKVVQ---LLIEH-GAVV--------DH---TCNQ-GATALC 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1268) ---SSYIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLG 1 ( 1323) HRDSAYISSSPLG---SHQVFDFRSSSSVGSPTRQTYQSTSPALSPTHQNSHYRPSPPHT 2 ( 711) ---IAA----QEG------------HIDVVQVLLEHGADPNHADQFGRTAMRVAAK---- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1325) SGQSAVRNGSMKVQ---ISSQ-----NP-PPSPM---PGRIAAAPAGSRTQHLEGTGT-- 1 ( 1380) S--PAHQGGSYRFSPPPVGGQGKEYPSP-PPSPLRRGPQYRASPPAESMSVYRSQSGSPV 2 ( 748) NGHSQIIKLLEKYG---ASSL-----NGCSPSPV---H-TMEQKPLQSLSSKVQSLTI-- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1371) -FTTRAGCGHFGDR----LG----------------PSQNVRLQCGE------NGP---- 1 ( 1437) RYQQETSVSQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSPAV 2 ( 794) -KSNSSGSTGGGD-----MQ----------------PS----LRGLP------NGP---- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1400) --------------AHPLPSKTKTTE--------RLLSHSSVA--VDAAPPNQ------- 1 ( 1497) HSSTVIPTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLS 2 ( 818) --------------THAFSSPSESPD--------S-------T--VD------------- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1429) -------GGLATCSDVRHPASL--------------------------------TSSGSS 1 ( 1557) AGAICQHGGLTKEDLPQRPSSAYRGGVRYSQTPQIGRSQSASYYPVCHSKLDLERSSSQL 2 ( 834) ----------------RQKSSL--------------------------------SNNSLK 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1450) GSPSSS-------------------------------IKMSSSTSSLTSSSSFSDGFK-- 1 ( 1617) GSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPTFRPS 2 ( 846) SSKNSS-------------------------------LRTTSSTA--TAQTVPIDSFH-- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1477) --VQGPDTRIK-------DKV--VTHVQSG--TAEHRPRNTPFMGIMDKTARFQQQSN-- 1 ( 1677) SSIQQMEIPLKPAYERSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLH 2 ( 871) --NLSFTEQIQ-------QHS--LPRSRSR--QSIVSPSST--------TQSLGQSHN-- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1522) PPSRS--WHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLS----- 1 ( 1737) QQNRT--WAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLL----- 2 ( 908) SPSSEFEWSQVKPS--LKSTKASKGGKSENSAKSG--SAGKKAKQSNSSQPKVLEYEMTQ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1575) -------A----SVH----NGAQVKELE-ESKCQIPVHSQENRITKT--VSHLYQESISK 1 ( 1790) -------EDDYYSPHGMLANGSR-GDLL-ERVSQASSYP-DVKVARTLPVAQAYQDNLYR 2 ( 964) FDRRGPIA----KSG----TAAPPKQMPAESQCKIMIPSAQQEIGRS--QQQFLIHQQSG 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 1617) QQPHISNEAHRSHLTAAKPKRSFIESNV 1 ( 1840) Q---LSRDSRQGQTSPIKPKRPFVESNV 2 ( 1014) EQ.......................... 3 ( -) ............................ 4 ( -) ............................ 5 ( -) ............................ //