# 0 KIAA1223, 1089 aa # 1 KIAA0379 (1059 aa) # 2 KIAA1728 (1644 aa) # 3 KIAA1250 (1777 aa) # 4 KIAA0697 (2486 aa) # 5 KIAA1636 (1864 aa) // exp sw-scr id% from to 1 3.9e-16 1022 32.8 59 730 2 1.2e-15 799 25.0 528 1618 3 1.4e-15 705 34.7 1 399 4 1.4e-14 901 32.7 112 745 5 4.1e-12 805 25.6 572 1555 // 0 ( 1) LFVRKQFAKVQPILNVILAACRPLTITELYHAVWTKNMS--LTLE--DFQRKLDILSKLL 1 ( -) ............................................................ 2 ( 528) FMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWE--DFQQRMDALSCFL 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 572) ...QSSFDRVMPLLNVAVASLHPLTDEHIFQAINAGSIE--GTLEWEDFQQRMENLSMFL // 0 ( 57) VDGLGNTKILFHYSFAEWLL-DVKHCTQ-KYLCNAAEGHRMLAMSYTCQAKNLTPLEAQE 1 ( -) ............................................................ 2 ( 586) IKRRDKTRMFCHPSFREWLVWRADGENT-AFLCEPRNGHALLAFMFSRQEGKLNRQQTME 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 627) IKRRDMTRMFVHPSFREWLI-WREEGEKTKFLCDPRSGHTLLAFWFSRQEGKLNRQQTIE // 0 ( 115) FALHLINSNL--------QLETAEL-ALWMIWNG---TPVRDSLSTLIPKEQEVLQLLVK 1 ( 59) ..................................................DAEIIELLIL 2 ( 645) LGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLIL 3 ( 1) ......................................................LQLSVK 4 ( -) ............................................................ 5 ( 686) LGHHILKAHI--------FKGLSK-----KVGVS---SSILQGL--WISYSTEGLSMALA // 0 ( 163) AGAHVNSEDDRTS-----CIVRQALER--EDSIRTLLDNGASVNQCDS--NGRTLLANAA 1 ( 69) SGARVNAKDSKWL-----TPLHRAVASCSEEAVQVLLKHSADVNARDK--NWQTPLHIAA 2 ( 705) GGANVNYRTEVLNNAPILC-VQSHLGH--EEVVTLLLEFGACLDGTSE--NGMTALCYAA 3 ( 7) MSVLISQ-----S-----VINYVEEEN--IPALKALLEKCKDVDERNE--CGQTPLMIAA 4 ( -) ............................................................ 5 ( 728) SLRNLYTPNIKVS--------------------RLLILGGANINYRTEVLNNAPILCVQS // 0 ( 214) YSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG-- 1 ( 122) ANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKD-- 2 ( 760) AAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPG-PPQPGTL 3 ( 53) EQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGG-- 4 ( 112) ................................................ANAGQSDN---- 5 ( 768) HLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNG-- // 0 ( 272) ------WTALRSAAWGGHTEVVSALLYAG----VKVDCADAD-SRTVLRAAAWGGHEDIV 1 ( 180) ------RRAIHWAAYMGHIEVVKLLVSHG----AEVTCKDKK-SYTPLHAAASSGMISVV 2 ( 819) RKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVC 3 ( 111) ------WTALMWACYKGRTDVVELLLSHG----ANPSVTGLY-SVYPIIWAAGRGHADIV 4 ( 120) -------RSLAEACSEGDVNAVRKLLIEG----RSVNEHTEE-GESLLCLACSAGYYELA 5 ( 826) ------QCALVHAALRGHLEVVKFL----------IQC-------------------DWT // 0 ( 321) LNLLQHGAEVNKADNEGR-TALIAAAYMGHREIVEHLLD----HGAEVNHEDVDGRTAL- 1 ( 229) KYLLDLGVDMNEPNAYGN-TPLHVACYNGQDVVVNELID----CGAIVNQKNEKGFTPL- 2 ( 879) ELLLGHGAAVSRTNRRGV-PPLFCAARQGHWQIVRLLLE----RGCDVNLSDKQGRTPL- 3 ( 160) HLLLQNGAKVNCSDKYGT-TPLVWAARKGHLECVKHLLA----MGADVDQEGANSMTAL- 4 ( 168) QVLLAMHANVEDRGIKGDITSLMAAANGGHVKIVKLLLA----HKADVNAQSSTGNTAL- 5 ( 851) MAGQQQG--VFKKSHAIQ-QALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLW // 0 ( 375) SVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADV 1 ( 283) HFAA----ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVI 2 ( 933) MVAA-C----EGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAI 3 ( 214) IVAV-----KGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYV 4 ( 223) TYA--C---AGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGI 5 ( 908) GETALTAAAGRGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADV // 0 ( 435) D-HTDNNGRTPLLAAASMGHASVVNTLLFWGAA--------------------------- 1 ( 339) D-CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKL 2 ( 988) D-QTDKNGRTPLDLAAFYGDAETVLYLVEKGAV--------------------------- 3 ( 269) N-IPDRSGDTVLIGAVRGGHVEIVRALLQKYAD--------------------------- 4 ( 278) NTHSNEFKESALTLACYKGHLEMVRFLLEAGAD--------------------------- 5 ( 968) N-MADKQGRTPLMMAASEGHLGTVDFLLAQGAS--------------------------- // 0 ( 467) ------VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHR 1 ( 398) LSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNY 2 ( 1020) ------IEHVDHSGMRPLDRAIGCRNTSVVVALLRKG---AKLGNAAWA---MATSKPDI 3 ( 301) ------IDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNI 4 ( 311) ------QEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHV 5 ( 1000) ------IALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDA // 0 ( 521) LIC--EALIEQGARTNEIDNDGRIPF-ILASQEGHYDCVQILLENKSNID-QRGYDG-RN 1 ( 458) QCL--FALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPG-IRDKQG-YN 2 ( 1068) LIILLQKLMEEG---NVMYKKGKMKE---AAQRYQYALRKFPREGFGE-D-MRPFNELRV 3 ( 355) EVV--ELLLDKGAKVSAVDKKGDTPL-HIAIRGRSRKLAELLLRNPKD............ 4 ( 365) ELA--ALLIERGASLEEVNDEGYTPL-MEAAREGHEEMVALLLGQGANINAQTEETQ-ET 5 ( 1054) EVV--QFLVDHGAMIEHVDYSGMRPL-------------------------DRAVGC-RN // 0 ( 576) ALRVAALEGHRDIVELLFSH----------GADVN--CKD---ADGRPT---LY------ 1 ( 514) AVHYSAAYGHRLCLQLIASETPLDVLMETSGTDM---LSD---SDNRATISPLH------ 2 ( 1120) SLYLNLSRCRRKTND--FGM----------AEEFA--SKA---LELKPK---SYEAFYAR 3 ( -) ............................................................ 4 ( 421) ALTLACCGGFLEVADFLIKA----------GADIELGCST-------PL---ME------ 5 ( 1086) T----------SVVVTLLKK----------GAKIG--PATWAMATSKPD---IM------ // 0 ( 612) ILALEN--QLTMAEYFLENGANVEASDAEGRTAL---HVSCWQGHMEMVQVLIA-YHADV 1 ( 562) LAAYHG--HHQALEVLVQSLLDLDVRNSSGRTPL---DLAAFKGHVECVDVLIN-QGASI 2 ( 1160) ARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPL 3 ( -) ............................................................ 4 ( 455) A-AQEG--HLELVKYLLAAGANVHATTATGDTAL---TYACENGHTDVADVLLQ-AGADL 5 ( 1115) IILLSK--LMEEGDMFYKKGKVKEAAQ-RYQYAL---KKFPREGFGEDLKTFRE-LKVSL // 0 ( 666) --NAADN-EKRSALQSAAWQGHVKVVQLLI---E-HGAVVDHTC-NQGATAL-CIAAQEG 1 ( 616) --LVKDYILKRTPIHAAATNGHSECLRLLIGNAE-PQNAVDIQD-GNGQTPL-MLSVLNG 2 ( 1220) --NDSEN-EEDTP--TPGLSDHFHSEETEE---E-ETSPQEESV-SPTPRSQPSSSVPSS 3 ( -) ............................................................ 4 ( 508) --EHESE-GGRTPLMKAARAGHVCTVQFLI---S-KGANVNRTTANNDHTVL-SLACAGG 5 ( 1168) LLNLSRC-RRKMNDFGMAEEFATKALELKP---KSYEAYYARAR-AKRSSRQ-FAAALED // 0 ( 717) HIDVVQVLLE-HG--ADPNHADQFGRTAMRVAAKNG-------HSQIIKLLEKYGASSL- 1 ( 671) HTDCVYSLLN-KG--ANVDAKDKWGRTALHRGAVTG-------HEECVDALLQHGAKCLL 2 ( 1270) YIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSA 3 ( -) ............................................................ 4 ( 560) HLAVVELLLA-HG--ADPTHRLKDGSTMLIEAAKGG-------HTSVVCYLLDYPNNLL- 5 ( 1222) LNEAIKLC---------PNNRE-IQRLLLRVEEECR-------QMQQPQQPPPPPQPQQ- // 0 ( 766) --N---GC----------SPS------PVH-TMEQKP---LQSLSSKVQSL-------TI 1 ( 721) R-D---SR----------GRT------PIH.............................. 2 ( 1330) VRN---GSMKVQISSQNPPPS------PMPGRIAAAP---AGSRTQHLEGT-------GT 3 ( -) ............................................................ 4 ( 609) --S---AP----------PPDVTQLTPPSH-DLNRAPRVPVQALPMVVPPQEPDKPPANV 5 ( 1264) --QLPEEA----------EPE------PQH-----ED---IYSVQDIFEEE-------YL // 0 ( 794) KSNSSGSTGG--GD-MQPS----LRGLP-NGPTHAFSSPSESPDS-------TVD----- 1 ( -) ............................................................ 2 ( 1371) FTTRAGCGHF--GDRLGPSQNVRLQCGE-NGPAHPLPSKTKTTERLLSHSSVAVDAAPPN 3 ( -) ............................................................ 4 ( 653) ATTLPIRNKA--AS-KQKS----SSHLPANSQDVQGYITNQSPES-------IVE----- 5 ( 1291) EQDVENVSIGLQTE-ARPS-----QGLP------VIQSPPSSPPH--------------- // 0 ( 834) ----------RQKSSLSN--NSLKSS--KNSSLRTTSS--TATAQTVPIDSFHNLSFT-- 1 ( -) ............................................................ 2 ( 1428) QGGLATCSDVRHPASLTS--SGSSGS--PSSSIKMSSS--TSSLTS-------SSSFS-- 3 ( -) ............................................................ 4 ( 694) ----------EAQGKLTELEQRIKEAIEKNAQLQSLE---LAHADQLTKEKIEELNKTRE 5 ( 1324) ----------RDSAYISS--SPLGSH--QVFDFRSSSSVGSPTRQTYQSTS-PALSPT-- // 0 ( 876) EQIQQHSLPRSRSRQSIVSPSSTTQSLGQSHN-SP-------SSEFEWSQVKPSLKSTKA 1 ( -) ............................................................ 2 ( 1473) DGFKVQG-PDTRIKDKVVTHVQSGTAEHRPRN-TPFMGIMDKTARFQQQSNPPSRSWHCP 3 ( -) ............................................................ 4 ( 741) EQIQK....................................................... 5 ( 1367) HQ-NSHYRPSP--------PHTSPAHQGGSYRFSP-------PPVGGQGKEYPSPPPSPL // 0 ( 928) SKGGKSENSAKSGSAGKKAKQSNSSQPKVLEYEMTQFDRRGPIAKSGT-------AAPPK 1 ( -) ............................................................ 2 ( 1531) APEGLLTNT--SSAAG--LQSANTEKPSLM--QVGGYNNQAKTCSVSTLSASVHNGAQVK 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 1411) RRGPQYRASPPAESMSVYRSQSGSPVRYQQETSVSQLPGRPKSPLSKM-------AQRPY // 0 ( 981) QMP----AESQCKIMIPSAQQEIGRSQQQF-LIHQQSGEQKKRNG-IMTNPNYHLQSNQV 1 ( -) ............................................................ 2 ( 1585) ELE-----ESKCQIPVHSQENRITKTVSHL-YQESISKQQ.................... 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 1464) QMPQLPVAVPQQGLRLQPAKAQIVRSNQPSPAVHSSTVIPTGAYGQVAHSMASKYQSSQG // 0 ( 1035) FLGRVSVPRTM-QDRGHQEVLEGYPSSETELSLKQALKLQIEGSDPSFNYKKETPL 1 ( -) ........................................................ 2 ( -) ........................................................ 3 ( -) ........................................................ 4 ( -) ........................................................ 5 ( 1524) DIG-VSQSRLVYQGSIGGIVGDGRPVQHVQASL....................... //