# 0 KIAA1964, 757 aa # 1 KIAA1092 (1154 aa) # 2 KIAA0450 (1182 aa) # 3 KIAA1069 (787 aa) # 4 KIAA1516 (2304 aa) # 5 KIAA0581 (1218 aa) // exp sw-scr id% from to 1 3.8e-60 1622 37.2 158 907 2 9.1e-42 1601 35.6 51 907 3 3.7e-28 1229 35.0 1 640 4 1.1e-20 877 30.5 1330 1992 5 5.2e-17 1066 30.6 118 798 // 0 ( 1) PSPPTPSDGGTKRPGLRALKKMGLTEDEDVR---AMLRGSRLRKIRSRTWHKERLYRLQE 1 ( 158) ...................KKISSASDC-IN---SMVEGSELKKVRSNSRIYHRYFLLDA 2 ( 51) ..PPAMEEPGP--PG-------GLSQDQVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDE 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 58) DGLSV-WFQRRIPRAPSQHIFFVQHIEAVREGHQSEGLRRF-GGAFAPAR-C-LTIAFKG 1 ( 195) DMQSLRWEPSK--KDSEKAKIDIKSIKEVRTGKNTDIFRSN-GISDQISEDCAFSVIYGE 2 ( 100) HRSCIRW---RPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNC-C-FSIYHGS 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 114) RRKNLDLAAPTAEEAQRWVRGLTKL----RARL---DAM--SQRERL-DHWIHSYLHRAD 1 ( 252) NYESLDLVANSADVANIWVTGLRYLISYGKHTL---DMLESSQDNMR-TSWVSQMFSEID 2 ( 155) HRESLDLVSTSSEVARTWVTGLRYL----MAGISDEDSL--ARRQRTRDQWLKQTFDEAD 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 118) ...HLNLVAFQEEVAKEWTNEVFSL----ATNL-----L--AQNMSR-D----AFLEKAY // 0 ( 164) SNQDSKMSFK---EIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEG-AEI--EE---- 1 ( 308) VDNLGHITLC---NAVQCIRNLNPGLKTSKIELKFKEL-HKSKDK-AG-TEVTKEE---- 2 ( 209) KNGDGSLSIG---EVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEF--CA---- 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( 159) TKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQ-EDF--TPEVYR // 0 ( 214) -FLR---RLLKRPELEEIFHQYSGEDR-VLSAPELLEFLE-D-QGEEGAT---------L 1 ( 358) -FIEVFHELCTRPEIYFLLVQFSSNKE-FLDTKDLMMFLEAE-QGVAHIN---------E 2 ( 260) -FYK---MMSTRRDLYLLMLTYSNHKD-HLDAASLQRFLQVE-QKMAGVT---------L 3 ( 1) .............DLYLLLLSYSDKKD-HLTVEELAQFLKVE-QKMNNVT---------T 4 ( 1330) .................................QLNDFLV-NCQGEH-CT---------Y 5 ( 216) VFLN---NLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFIN-L-KQRDPRLNEILYPPLKQ // 0 ( 258) ARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCV-FQDMNQPLAHYFI 1 ( 406) EISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKV-CQDMKQPLSHYFI 2 ( 305) ESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHV-HQDMTQPLSHYFI 3 ( 37) DYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEV-YQDMDQPLCNYYI 4 ( 1346) DEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYI 5 ( 271) EQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDL-NEDMSQPLSHYFI // 0 ( 317) SSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGE--PVIYHGHTLTSKIL 1 ( 465) NSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNE--PVIYTGHTMTSQIV 2 ( 364) TSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGE--PIVHHGYTLTSKIL 3 ( 96) ASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGE--PVVHHGYTLTSKIL 4 ( 1406) ESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGM--PIIYHGHTLTTKIP 5 ( 330) NSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEIS // 0 ( 375) FRDVVQAVRDHAFTLSPYPVILSLENHCGL-EQQAAMARHLCTILGDMLVTQAL---DSP 1 ( 523) FRSVIDIINKYAFFASEYPLILCLENHCSI-KQQKVMVQHMKKLLGDKLYTT------SP 2 ( 422) FKDVIETINKYAFIKNEYPVILSIENHCSV-IQQKKMAQYLTDILGDKLDLSSV---SSE 3 ( 154) FRDVVETINKHAFVKNEFPVILSIENHCSI-QQQRKIAQYLKGIFGDKLDLSSV---DTG 4 ( 1464) FKEVVEAIDRSAFINSDLPIIISIENHCSL-PQQRKMAEIFKTVFGEKLVTKFLFETDFS 5 ( 390) FKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPL---EK- // 0 ( 431) NPEE----LPSPEQLKGRVLVKGKKLPAARSE-------------------DG-----RA 1 ( 576) NVEESY--LPSPDVLKGKILIKAKKLSSNCSGV------------------EG-----DV 2 ( 478) DATT----LPSPQMLKGKILVKGKKLPANISE-------------------DA-----EE 3 ( 210) ECKQ----LPSPQSLKGKILVKGKKLPYHLGD-------------------DA-----EE 4 ( 1523) DDPM----LPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRP 5 ( 446) YPLESGVPLPSPMDLMYKILVKNKKKSHKSSE-------------------GSGK---KK // 0 ( 463) --LSDR----------------------EEEEE-DDE----------------------- 1 ( 611) --TDED----------------------EGAEM-SQR----------------------- 2 ( 510) GEVSDE----------------------DSADEIDDDCKLLNGDASTNRKRVENTAKRKL 3 ( 242) GEVSDE----------------------DSADE-IED----------------------- 4 ( 1579) --ANNE----------------------EEEDE-EDEYDYDYESLSDDNILEDRPENKSC 5 ( 484) --LSEQASNTYSDSSSMFEPSSPGAGEADTESD-DDD----------------------- // 0 ( 475) ---------------------------------E-----------EEEEVE----AAAQR 1 ( 623) ---------------------------------M-----------GKENME----QPNNV 2 ( 548) DSLIKESKIRDCEDPNNFSVSTLSPSGKLGRKSK-----------AEEDVESGEDAGASR 3 ( 256) ---------------------------------ECKFKLHYSNGTTEHQVE----SFIRK 4 ( 1614) NDKLQF---------------------------E-----------YNEEIP----KRIKK 5 ( 518) ---------------------------------D-----------DDDCKK----SSMDE // 0 ( 487) --------------------------R------------------LA---K--------- 1 ( 635) --------------------------P------------------VK---RF-------- 2 ( 597) --------------------------RNGRLVVGSFSRRKKKGSKLK---KAASVEEGDE 3 ( 279) --------------------------K------------------LE---SLLKES---- 4 ( 1632) ADNSACNKGKVYDMELGEEFYLDQNKK------------------ES---R--------- 5 ( 530) --------------------------G------------------TAGSEA--------- // 0 ( 491) -QI----------------------------SP--------------ELS-ALAVYCHA- 1 ( 640) -QL----------------------------CK--------------ELS-ELVSICKS- 2 ( 628) GQD----------------------------SPGGQSRGATRQKKTMKLSRALSDLVKY- 3 ( 288) -QIRDKEDPDSFTVRALLKATHEGLNAHLKQSP--------------DVK-ESGKKSHGR 4 ( 1662) -QI----------------------------AP--------------ELS-DLVIYCQA- 5 ( 537) -MA----------------------------TE--------------EMS-NLVNYIQP- // 0 ( 506) ------------TR---LRTLHPA------------------P-NAPQP----------- 1 ( 655) ------------VQ---FKEFQVS------------------F-QVQKY----------- 2 ( 659) ------------TK---SVATHDI------------------EMEAASS----------- 3 ( 332) SLMTNFGKHKKTTK---SRSKSYS------------------T-DDEED----------- 4 ( 1677) ------------VKFPGLSTLNASGSSRGKERKSRKSIFGNNP-GRMSPGETASFNKTSG 5 ( 552) ------------VK---FESFEIS------------------K-KRNKS----------- // 0 ( 521) ---CQ------------------------------VS----------------------- 1 ( 670) ---WE------------------------------VC----------------------- 2 ( 675) ---WQ------------------------------VS----------------------- 3 ( 359) ---TQ------------------------------QSTGKEGGQLYRLGRRRKTMKLCRE 4 ( 1724) KSSCEGIRQTWEESSSPLNPTTSLSAIIRTPKCYHIS----------------------- 5 ( 567) ---FE------------------------------MS----------------------- // 0 ( 525) --------------------------SLSERKAKKLIREAGNSFVRHNARQLTRVYPLGL 1 ( 674) --------------------------SFNEVLASKYANENPGDFVNYNKRFLARVFPSPM 2 ( 679) --------------------------SFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSY 3 ( 386) LSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAY 4 ( 1761) --------------------------SLNENAAKRLCRRYSQKLTQHTACQLLRTYPAAT 5 ( 571) --------------------------SFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGT // 0 ( 559) RMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQ----P 1 ( 708) RIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMRE----E 2 ( 713) RVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNP 3 ( 446) RIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCGYVLKPQQMCK----- 4 ( 1795) RIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWD----K 5 ( 605) RVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRR----P // 0 ( 615) DSTFDP----E----YPGPPRTTLSIQ--VLTAQQLPK----LNAEKPHS-IVDPLVRIE 1 ( 764) VSFFSA----NTKDSVPGVSPQLLHIK--IISGQNFPK----PKGSGAKGDVVDPYVYVE 2 ( 773) NSE-DP---------LPGQLKKQLVLR--IISGQQLPKPRDSMLGDRGE--IIDPFVEVE 3 ( 501) -GTFNPFSGDP----LPANPKKQLILK--VISGQQLPKPPDSMFGDRGE--IIDPFVEVE 4 ( 1851) NCPMYQ----K----FSPLERDLDSMDPAVYSLTIVSG----QNVCPSNS-MGSPCIEVD 5 ( 661) DKHFDP----FTEGIVDGIVANTLSVK--IISGQFL--------SDKK----VGTYVEVD // 0 ( 660) IHGVPADCARQ--ETDYVLNNGFNPRWGQT-LQFQ-LRAPELALVRFVVEDYDATSPNDF 1 ( 814) IHGIPADCAEQ--RTKTVHQNGDAPIFDES-FEFQ-INLPELAMVRFVVLDDDYIG-DEF 2 ( 819) IIGLPVDCSRE--QTRVVDDNGFNPTWEET-LVFM-VHMPEIALVRFLVWDHDPIG-RDF 3 ( 552) IIGLPVDCCKD--QTRVVDDNGFNPVWEET-LTFT-VHMPEIALVRFLVWDHDPIG-RDF 4 ( 1898) VLGMPLDSCHF--RTKPIHRNTLNPMWNEQ-FLFR-VHFEDLVFLRFAVVENNSSA---V 5 ( 703) MFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGK----F // 0 ( 716) VGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFIQIRIQRS 1 ( 869) IGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAI... 2 ( 874) IGQRTLAFSSMMPGYRHVYL---EG--MEEASIFVHVAV... 3 ( 607) VGQRTVTFSSLVPGYRHVYL---EG--LTEASIFVHITI... 4 ( 1951) TAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRMEE 5 ( 759) IGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVK.. //