# 0 KIAA1749, 1047 aa # 1 KIAA1319 (1208 aa) # 2 KIAA0866 (1984 aa) # 3 KIAA2034 (1571 aa) # 4 KIAA1000 (1956 aa) # 5 KIAA1512 (2010 aa) // exp sw-scr id% from to 1 2.2e-32 1671 33.2 153 1182 2 3.8e-14 875 26.0 1032 1941 3 1.2e-10 728 24.6 636 1522 4 3.6e-09 600 24.7 1225 1956 5 4.1e-08 557 24.0 1233 2002 // 0 ( 1) PLTAHSPHAHPETKKTRPDVLPFRRQDSAGPVLDGARSRRSSSSSTTPTSANSLYRFLLD 1 ( -) ............................................................ 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 61) DQECAIHADNVNRHENR-RYIPFLPGTGRDIDTGSIPGVDQLIEKFDQKPGLQRRGRSGK 1 ( 153) ........DPSNRSNSMLELAPKVASPGSTIDTAPLSSVDSLINKFDSQLGGQARGRTGR 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 120) RNRI-NPDDRKRSRSVDSAFPFGL------QGNSEYL--IEFSRNLGK-SSEHLLRPSQV 1 ( 205) RTRMLPPEQRKRSKSLDSRLPRDTFEERERQSTNHWTSSTKYDNHVGT-SKQ----PAQS 2 ( 1032) ........................................EKAKNLTKLKNKHESMISEL 3 ( -) ............................................................ 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 170) CPQRPLSQERRGKQS---VGRTFAKLQGAAHG--ASCAH--SRP----------PQ--PN 1 ( 260) QNLSPLSGFSRSRQTQDWVLQSFEEPRRSAQD--PTMLQFKSTPDLLRDQQEAAPP--GS 2 ( 1052) --EVRLKKEEKSRQE---LEKLKRKLEGDASDFHEQIAD--LQA----------QI--AE 3 ( 636) .....LRKEEKGRQE---LEKLKRRLDGESSE--LQEQM--VEQ----------QQRAEE 4 ( -) ............................................................ 5 ( -) ............................................................ // 0 ( 211) ID-------GKVLETEGSQESTVIRAPSL----------------------GA------Q 1 ( 316) VDHMKATIYGILREGSSESETSVRRKVSLVLEKMQPLVMVSSGSTKAVAGQGE------L 2 ( 1093) LK-------MQLAKKEEELQAALARLDDE----------------------IA------Q 3 ( 674) LR-------AQLGRKEEELQAALARAEDE----------------------GGARAQLLK 4 ( -) ............................................................ 5 ( 1233) ..............SAGQREGCRKREAEL----------------------GR------L // 0 ( 236) S----KKEEE--VKTATATL---MLQN-RAAATSPDSGAKKISVKTFPSA---------- 1 ( 370) T----RKVEE--LQRKLDEE---VKKR-QKLEPSQVGLERQLEEKTEECSRLQELLERRK 2 ( 1118) KNNALKKIRE--LEGHISDLQEDLDSE-RAARNKAEKQKRDLGEELEALK---------- 3 ( 705) S----LREAQ--AALAEAQE---DLESERVARTKAEKQRRDLGEELEALR---------- 4 ( -) ............................................................ 5 ( 1251) R----RELEEAALRHEATVA---ALRR-KQAEGAAELGEQVDSLQ--------------- // 0 ( 276) SNTQATPDLLKGQQELTQQTNE-----ETA--KQILYNYLK--EGSTDNDDA-------T 1 ( 420) GEAQQSNKELQNMKRLLDQGEDLRHGLETQ--VMELQNKLKHVQGPEPAKEVLLKDLLET 2 ( 1165) TELEDTLDSTATQQELRAKREQ-----EVTVLKKALDEETR--SHEAQVQEM-------R 3 ( 746) GELEDTLDSTNAQQELRSKREQ-----EVTELKKTLEEETR--IHEAAVQEL-------R 4 ( 1225) .........LEGQVENLQQVKQKL---EKD--KSDLQLEVD--DLLTRVEQM-------T 5 ( 1288) ---RVRQKLEKEKSELRMEVDDLAANVETL--TRAKASAEK--LCRTYEDQL-------S // 0 ( 320) KRKVNLVFEKIQT------LKS--RAAGSAQG--NNQACNS-TSEVKDLLEQKSKLTIEV 1 ( 478) RELLEEVLEGKQRVEEQLRLRE--RELTALKGALKEEVASR-DQEVEHVRQQYQR---DT 2 ( 1211) QKHAQAVEELTEQ------LEQFKRAKANLDK--NKQTLEKENADLAGELRVLGQAKQEV 3 ( 792) QRHGQALGELAEQ------LEQ--ARRGKGAW--EKTRLAL-EAEVSELRAELSSLQTAR 4 ( 1262) RAKANA--EKLCT------LYE--ERLHEATA--KLD--KV-TQLANDLAAQKTKLWSES 5 ( 1334) EAKI-----KVEE------LQR--QLADASTQ--RGRLQTE-SGELSRLLEEKECLISQL // 0 ( 369) A-----------E-LQRQLQLEVKNQQ-------------NIKEERERMRANLEELRSQH 1 ( 532) E-----------Q-LRRSMQDATQDHA-------------VLEAERQKMSALVRGLQREL 2 ( 1263) E-----------H-KKKKLEAQVQELQ-------------SKCSDGERARAELNDKVHKL 3 ( 841) Q-----------EGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGAL 4 ( 1307) G-----------E-FLRRLEEKEALIN-------------QLSREKSNFTRQIEDLRGQL 5 ( 1378) SRGKALAAQSLEE-LRRQLEEESKAKS-------------ALAHAVQALRHDCDLLREQH // 0 ( 404) NEKVEENSTLQQRLEESEGE---LRKNLEEL------FQVKMEREQHQ-----TEIRDLQ 1 ( 567) EETSEETGHWQSMFQKNKED---LRATKQEL------LQLRMEKEEME-----EE---LG 2 ( 1298) QNEVESVTGM---LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 3 ( 890) NEAESKTIRLSKELSSTEAQ---LHDAQELL------QEETRAKLALG-----SRVRAME 4 ( 1342) EKETKSQSALAHALQKAQRDCDLLREQYEEE------QEVKAELHRTL-----SKVNAEM 5 ( 1424) EEEAEAQAELQRLLSKANAE-------------------VAQWRSKYE-----ADAIQRT // 0 ( 450) DQLSEMHDELD---S---AKRS--EDREKG-----ALIEELLQAKQDLQDLLIAKEEQED 1 ( 610) EKIEVLQRELE---Q---ARASAGDTRQVE-----VLKKELLRTQEELKELQAERQSQEV 2 ( 1355) EERNSLQDQLD---EEMEAKQN--LERHIS-----TLNIQLSDSKKKLQDFASTVEALEE 3 ( 936) AEAAGLREQLEEEAA---ARER--AGRELQ-----TAQAQLSEWRRRQEEEAGALEAGEE 4 ( 1391) VQW-RMKYENN---V---IQRT--EDLED------AKKELAIRLQEAAEAMGVANARNAS 5 ( 1460) EELEEAKKKL--------ALRL--QEAEEGVEAANAKCSSLEKAKLRLQT------ESED // 0 ( 497) LLRKRERELTALKGALKE--EVSSHD----------QEMDKLKEQYDAELQALRESVEEA 1 ( 659) AGRHRDRELEKQLAVLRV--E-ADRG----------RELEEQNLQLQKTLQQLRQDCEEA 2 ( 1405) GKKRFQKEIENLTQQYEE--KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 3 ( 986) ARRRAAREAEALTQRLAE--KTETVD----------R-LERGRRRLQQELDDATMDLEQQ 4 ( 1436) LERARHQLQLELGDALSDLGKVRSAA----------ARLDQKQLQSGKALADWKQKHEES 5 ( 1504) VTLELERATSA-AAALDK--KQRHLE----------RALEERRRQ-EEEMQRELEAAQRE // 0 ( 545) T-------KNV--EVLASR----SNTS-----EQDQAGTE-MRV--K------LLQEENE 1 ( 706) S-------KAK--MVAEAE----ATVL-----GQRRAAVE-TTL--R------ETQEEND 2 ( 1463) R-------KFD--QLLAEE----KNISSKYADERDRAEAE-ARE--KETKALSLARALEE 3 ( 1033) R-------QLV--STLEKK----QRKF-----DQLLAEEK-AAV--L------RAVEERE 4 ( 1486) QALLDASQKEV--QALSTELLKLKNTY-----EESIVGQETLRRENK------NLQEEIS 5 ( 1550) S-------RGLGTELFRLR----HGHE-----EALEALET-LKRENK------NLQEEIS // 0 ( 578) KLQGRSEELERRVAQLQRQIEDL---KGDEAKAKETLKK----YEGEIRQLEEAL----- 1 ( 739) EFRRRILGLEQQLKETRGLVDGG---EAVEARLRDKLQR----LEAEKQQLEEAL----- 2 ( 1507) ALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL----- 3 ( 1066) RAEAEGREREARALSLTRALEE-------EQEAREELER----QNRALRAELEALLSSKD 4 ( 1533) NLTNQVREGTKNLTEMEKVKKLI---EEEKTEVQVTLEE----TEGALERNESKI----- 5 ( 1587) DLTDQVSLSGKSIQELEKTKKAL---EGEKSEIQAALEE----AEGAL-ELEETK----- // 0 ( 626) -----VH----ARKEEKEAVSA---RRA----LENELEAAQGN---LSQTTQEQ-K---- 1 ( 787) -----NA----SQEEEGSLAAA---KRA----LEARLEEAQRG---LARLGQEQ-Q---- 2 ( 1561) -----EE----LEDELQATEDA---KLR----LEVNMQALKGQ---FERDLQAR-D---- 3 ( 1115) DVGKSVHELERACRVAEQAAND---LRAQVTELEDELTAAEDAKLRLEVTVQAL-K---- 4 ( 1581) -----LH----FQLELLE---A---KAE----LERKLSEKDEE---IENFRRKQ-QCTID 5 ( 1634) -----TL----RIQLELSQVKAEVDRKL----AEKDEECA--N---LRRNHQRAVE---- // 0 ( 662) QLSEK-LKEESEQKEQLRR-LKNEMENERWH---LGKTIEKLQKEMADIVEASRTSTLE- 1 ( 823) TLNRA-LEEEGKQREVLRR-GKAELEEQKRL---LDRTVDRLNKELEKIGEDSKQALQQ- 2 ( 1597) EQNEE--KRRQLQR-QLHE-YETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIK- 3 ( 1167) TQHERDLQGRDEAGEERRRQLAKQLRDA--E---VERDEERKQRTLAVAARKKLEGELEE 4 ( 1618) SLQSS-LDSEAKSRIEVTR-LKKKMEED------LNEMELQLSCANRQVSEATK-SLGQ- 5 ( 1672) SLQAS-LDAETRARNEALR-LKKKMEGD------LNDLELQLGHATRQATEAQAATRL-- // 0 ( 716) LQNQL---DEYKEKNRRELAEMQRQLK-------EKTLEAEKSRLTAMKMQDEMRLMEEE 1 ( 877) LQAQL---EDYKEKARREVADAQRQAK-------DWASEAEKTSGGLSRLQDEIQRLRQA 2 ( 1651) GREEA---IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 3 ( 1222) LKAQMASAGQGKEEAVKQLRKMQAQMK-------ELWREVEETRTSREEIFSQNRESEKR 4 ( 1668) LQIQI---KDLQMQ-LDDSTQLNSDLK-------EQVAVAERRNSLLQSELEDLRSLQEQ 5 ( 1722) MQAQL---KE-EQAGRDEEQRLAAELH-------EQ----------AQALERRASLLAAE // 0 ( 766) LRDYQ----RAQDEA-LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLV---KQMEDKVSQ 1 ( 927) LQASQ----AERDTA-RLDKELLAQRLQGLEQEAENKKRSQDDRARQL---KGLEEKVSR 2 ( 1708) LAAAE----RARKQADLEKEELAEE----LASSLSGRNALQDEKRRL-------EARIAQ 3 ( 1275) LKGLEAEVLRLQEEL-AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 4 ( 1717) TERGR----R------LSEEELLEATERINLFYTQNTSLLSQK--------KKLEADVAR 5 ( 1761) LEELR----AALEQG-ERSRRLAEQELLEATERLNLLHSQNTGLLNQK---KKLEADLAQ // 0 ( 818) LEMELEEERNNSDLLSERISRSREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSR 1 ( 979) LETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTR 2 ( 1753) LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 3 ( 1334) LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGR 4 ( 1759) MQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKR 5 ( 1813) LSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQAR // 0 ( 878) IIHLE-GSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1 ( 1039) LASSE-GFQKPSAS--LSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIE 2 ( 1813) LHEME-GAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE 3 ( 1394) LGEED-AGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVE 4 ( 1819) LAEAE-QMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAE 5 ( 1873) LEEAEQAALRGGKKQ-VQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAE // 0 ( 937) DEHLSLT---DQ-KDQL---SLRLKAMKRQVEEAEEEIDRLESSKKKLQREL---EEQMD 1 ( 1096) DERQHVN---DQ-KDQL---SLRVKALKRQVDEAEEEIERLDGLRKKAQREV---EEQHE 2 ( 1872) DERKMAE---QY-KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL---DEATE 3 ( 1453) EER-RVA---DQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL---EDVTE 4 ( 1878) EDKKNLSRMQTQ-MDKL---QLKVQNYKQQVEVAETQANQYLSKYKKQQHEL---NEVKE 5 ( 1932) EDRKNLARMQDL-VDKL---QSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERAD // 0 ( 987) MNEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGSLYEAPVSYTFSKDSTVASQ 1 ( 1146) VNEQLQARIKSLEKD-SWRKASRSAAESALKNEGLSSD...................... 2 ( 1925) SNEAMGREVNALKSKLR........................................... 3 ( 1506) SAESMNREVTTLRNRLR........................................... 4 ( 1931) RAEVAESQVNKLK--IKAREFGKKVQEE................................ 5 ( 1988) MAETQANKLRARTRD............................................. // 0 ( 1047) I 1 ( -) . 2 ( -) . 3 ( -) . 4 ( -) . 5 ( -) . //