# 0 KIAA1618, 1415 aa # 1 sp:Q9HCF4 (1550 aa) # 2 ref:NP_066005 (1063 aa) # 3 emb:CAH10615 (1061 aa) # 4 ref:XP_590465 (5169 aa) # 5 gb:EDL34702 (5229 aa) // exp sw-scr id% from to 1 0 9413 100.0 136 1550 2 0 5898 100.0 136 1008 3 0 5813 99.1 136 1006 4 1.4e-202 4903 55.0 50 1489 5 2.8e-196 4170 48.6 165 1560 // 0 ( 1) SQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQ 1 ( 136) SQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQ 2 ( 136) SQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQ 3 ( 136) SQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQ 4 ( 50) SPAQQCRPTHQSGKPPSVGKIPLEAMG---------HPLQGEAAGEAEAAMGAESLSSPA 5 ( 165) ...............PMRKNMPME-DGF-VHTEGSGSPLQGQA------AERTDAQSNLA // 0 ( 61) FQDHT------EGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGG 1 ( 196) FQDHT------EGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGG 2 ( 196) FQDHT------EGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGG 3 ( 196) FQDHT------EGEDQDASIPLGQRPVPG-GTGPPTSAGEGHSRTEDAAQELLLPESKGG 4 ( 101) PQDQTLAGALPEGNDHHSLSPFKGEDL-------PTSASEGSPREKDTAQELLLPEPKVD 5 ( 202) PSDLA------EVKDLNTSKPSVDKGLPLDG-GPALSAFKGHPKMTDASQKAPLPESKGE // 0 ( 115) SS---------------------EPGTELQTTE--------QQAGASAS----------- 1 ( 250) SS---------------------EPGTELQTTE--------QQAGASAS----------- 2 ( 250) SS---------------------EPGTELQTTE--------QQAGASAS----------- 3 ( 249) SS---------------------EPGTELQTTE--------QQA-ASAS----------- 4 ( 154) TS---------------------KPRKDLQTIR--------QLARAPASGVNLMPRIGLP 5 ( 255) TSGQEKKVPPIDAAASPVKTAGKETGEDVRKPKPSPVSPVASKHGDQPS----------- // 0 ( -) ------------------------------------------------------------ 1 ( -) ------------------------------------------------------------ 2 ( -) ------------------------------------------------------------ 3 ( -) ------------------------------------------------------------ 4 ( 185) CLNTLLCSAVLTTLHCLGRESTGTRFLGGGLWEGLSLYPELLTPVPGLVAEADPYAIEFK 5 ( -) ------------------------------------------------------------ // 0 ( 135) ------------------MAVDAV--AEPANAV----KGAG-KEMKEKT--QRMKQPPAT 1 ( 270) ------------------MAVDAV--AEPANAV----KGAG-KEMKEKT--QRMKQPPAT 2 ( 270) ------------------MAVDAV--AEPANAV----KGAG-KEMKEKT--QRMKQPPAT 3 ( 268) ------------------MAVDAV--AEPANAV----KGAG-KEMKEKT--QRMKQPPAT 4 ( 245) FPCAFCHFGPDVLGLYFFQASDAA--AESAVSV----KGVG-KDVKDKT--EEMKEPPTS 5 ( 304) ------------------VYEDVMCKAEPVSMELPCQREAGRKKFSEETWDQSWEGPGGM // 0 ( 168) T-------PPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKP-EGKN-RSAAAVK 1 ( 303) T-------PPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKP-EGKN-RSAAAVK 2 ( 303) T-------PPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKP-EGKN-RSAAAVK 3 ( 301) T-------PPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKP-EGKN-RSAAAVK 4 ( 296) V-------PASRNHRQEIATK--DQTALPGGKTGENEKAKPKDLKRP-EGNNGNNAAPVK 5 ( 346) LVGVLRGGSSLGFGGWEAELKGKLATPVRKSNEGGNTQ--PEDQRKPGEGRN-F-AAAVK // 0 ( 219) NEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKW 1 ( 354) NEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKW 2 ( 354) NEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKW 3 ( 352) NEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKW 4 ( 346) NEKEQRNQ--STQRAKESLLSSMEGIMVYFHAIISKHFEFNPHQHKVFVRGGKEFGEPAW 5 ( 402) TQQAAAPQQAAAPE-PTSAFNPRDTVTVYFHAIVSRHFGFNPEEHKVYVRGGEGLGQKGW // 0 ( 279) DSNICELHYTRDLGHDR-VLVEGIVCISKKHLDKYIPYKYVIYNG----E-SFEYEFIYK 1 ( 414) DSNICELHYTRDLGHDR-VLVEGIVCISKKHLDKYIPYKYVIYNG----E-SFEYEFIYK 2 ( 414) DSNICELHYTRDLGHDR-VLVEGIVCISKKHLDKYIPYKYVIYNG----E-SFEYEFIYK 3 ( 412) DSNICELHYTRDLGHDR-VLVEGIVCISKKHLDKYIPYKYVIYNG----E-SFEYEFIYK 4 ( 404) SHNVCEMHYSKDLHENG-SLIEGSTTISKQHVDKPIPYKYIICKG----KNSEEYEFIYT 5 ( 461) -TDACEMYCTQDL-HDLGSLVEGKMDIPRQSLDKPIPYKYVIHRGGSSKD-TVEYEFIYE // 0 ( 333) HQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQ 1 ( 468) HQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQ 2 ( 468) HQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQ 3 ( 466) HQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQ 4 ( 459) SQQKKGEYVNRCLRVKSSLLDSGDWHQYDDIICMKPPGTLKKLMNYITDGTRKDLMKGKQ 5 ( 518) QAQKKGEHVNRCLRVVSTSLGNGDWHQYDDIICMRSTGFFQQAKNRILDSTRKELLKGKK // 0 ( 393) IAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVK 1 ( 528) IAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVK 2 ( 528) IAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVK 3 ( 526) IAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVK 4 ( 519) IAAAVMLDSIFSILETWNAINLKNFFTQFQQFYSVIHVPMTYEGEEQPWSALRYKE-EVR 5 ( 578) QAAVVMLDRIFSVLQPWSDINLQSFMTQFLQFYSVVREPMIHDGRARKWTSLQYEEKEVW // 0 ( 453) RYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIE-LLL-EGSLDWLC 1 ( 588) RYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIE-LLL-EGSLDWLC 2 ( 588) RYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIE-LLL-EGSLDWLC 3 ( 586) RYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIE-LLL-EGSLDWLC 4 ( 578) KHLWECVTKKMAPFLE-TSGDPLPEDYPVKSKLGMGMIVLFLVEKFDFLLL-ENDLASLC 5 ( 638) TNLWEHVKKQMAPFLEGKSGESLPADCPVRSKLTLGLSILFMVEAAE-FTVPKKDLDSLC // 0 ( 511) HLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELA 1 ( 646) HLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELA 2 ( 646) HLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELA 3 ( 644) HLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELA 4 ( 636) HLLRLDTNSLGTFPKDLKDILETSQSWRVSLVNLCQMCMDKKVDFWVCALPVLHHCMDLS 5 ( 697) YLLIPSAGSPEALHSDLSPVLRIRQRWRIYLTNLCLRCIDERCDRWLGILPLLHTCMQKS // 0 ( 571) PRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLL 1 ( 706) PRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLL 2 ( 706) PRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLL 3 ( 704) PRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLL 4 ( 696) PPAQGSVTQPEDTWAALEGISFSEFRETRPDQKELLELMRKNRHLLNVDEFLFRSWFSLL 5 ( 757) PPKKNSKSQPEDTWAGLEGISFSEFRDKAPTRSQPLQFMQSKMALLRVDEYLFRSWLSVV // 0 ( 631) PLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLL 1 ( 766) PLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLL 2 ( 766) PLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLL 3 ( 764) PLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLL 4 ( 756) PLSNLAPYMEHFIDYLSQSPPHVLDCLLGTWYRLKGLEKISN----RNLQNIKNTFKMLL 5 ( 817) PLESLSSYLENSIDYLSDVPVRVLDCLQGISYRLPGLRKISN-QNMK--KDVENVFKMLM // 0 ( 691) RLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLV 1 ( 826) RLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLV 2 ( 826) RLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLV 3 ( 824) RLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLV 4 ( 812) HLLDIYQEKILEEPLIQPYLIVCLKLHETTCRISKAHTFYEMPALSAEIVRRIIILKPLV 5 ( 874) HLVDIYQHRIFGENLLQIYLTECLTLHETVCNITANHQFFEIPALSAELICKLLEL---- // 0 ( 751) DSAG-QRDE-----TGN-NSVQTVFQGTLAATKRWLREVFTKNMLTS-----SGA--SFT 1 ( 886) DSAG-QRDE-----TGN-NSVQTVFQGTLAATKRWLREVFTKNMLTS-----SGA--SFT 2 ( 886) DSAG-QRDE-----TGN-NSVQTVFQGTLAATKRWLREVFTKNMLTS-----SGA--SFT 3 ( 884) DSAG-QRDE-----TGN-NSVQTVFQGTLAATKRWLREVFTKNMLTS-----SGA--SFT 4 ( 872) DSAGGPGNE-----TGKKNSVKTVFQGTLAATRSWLRKNFKKSMFQAGYFYFSPV--TFA 5 ( 930) SPPG-HTDEGLPEKSYE-DLVTSTLQEALATTRNWLRSLFKSRMLSI-----SSAYVRLT // 0 ( 797) YVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNS-CWDTKGLEDS 1 ( 932) YVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNS-CWDTKGLEDS 2 ( 932) YVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNS-CWDTKGLEDS 3 ( 930) YVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNS-CWDTKGLEDS 4 ( 925) YSEEIEVWRRLVEIRFPVEHGWKESLLRDLEGRFKQEMPFFQICAFCNS-NWDATGAEDS 5 ( 983) YSEEMAVWRRLVEIGFPEKHGWKGSLLGDMEGRLKQEPPRLQISFFCSSQCRDG-GLHDS // 0 ( 856) VAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSAVITKSWP----RTA----D 1 ( 991) VAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSAVITKSWP----RTA----D 2 ( 991) VAKTFEKCIIEAVSSACQ.......................................... 3 ( 989) VAKTFEKCIIEAVSSACQ.......................................... 4 ( 984) VAKCFEMCAIEAVGLVCQSQTSILEKISYNNSRKCDTIVSAVITKSWP----RSGGEFVD 5 ( 1042) VSRSFEKCVIEA------SQTSVLEGLSCQDLQKFGTLLSAVITKSWPVHNGEPV----F // 0 ( 908) NFDDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTIL 1 ( 1043) NFDDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTIL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1040) NMGEVLNHLLIWPDIKHLFKLCGTNEKILANITKEGKKLMATADSVFTKVTSDLINGTIL 5 ( 1092) DVDEIFKYLLKWPDVRQLFELCGTNEKIIDNITEEGRQLMATAESVFQKVAGELENGTIV // 0 ( 968) VGQLELIIKHKNQFLDIWQLREKSLSPQDEKCAVEEALDWRREELLLLKKEKRCVDSLLK 1 ( 1103) VGQLELIIKHKNQFLDIWQLREKSLSPQDEKCAVEEALDWRREELLLLKKEKRCVDSLLK 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1100) VGQLELIVKHMNQFFDLWHLKNKSLSAQ----AKEDILNLRKKELDTLEKEKTYVDSLLK 5 ( 1152) VGQLELILEHQSQFLDIWNLNRRRLPSQEKACDVRSLLKRRRDDLLFLKQEKRYVESLLR // 0 ( 1028) MCGNVKHLIQVDFGVLAVRHSQDLSSKRLNDTMTVRLSTSS-NSQRATHYHLSSQVQEMA 1 ( 1163) MCGNVKHLIQVDFGVLAVRHSQDLSSKRLNDTMTVRLSTSS-NSQRATHYHLSSQVQEMA 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1156) LCGRVKDLIKVDFGEIAERYSEDLSGKKLNQVVTVSLSATSLDSTWATCYNLSPEVQEMA 5 ( 1212) QLGRVKHLVQVDFGNIEIIHSQDLSNKKLNEAV-IKLPNSS-SYKRETHYCLSPDIREMA // 0 ( 1087) GKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELQEVYDYLYQP 1 ( 1222) GKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELQEVYDYLYQP 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1216) RNAYLLKDSHIFPIFWAKAA---------QE----LSEPEENLERKIFQPEEVYEYLYCP 5 ( 1270) SKLDSLKDSHIFQDFWQETAESLNTLDKD---------PRELK----VSLPEVLEYLYNP // 0 ( 1147) SYRKFIKLHQDLKSGEVTLAEIDVIFKDFVNKYTDLDSELKIMCTVDHQGQRDWIKDRVE 1 ( 1282) SYRKFIKLHQDLKSGEVTLAEIDVIFKDFVNKYTDLDSELKIMCTVDHQGQRDWIKDRVE 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1263) CFKRFTKLYQDLKSGEVTFGEINDIFKDFVNKYSDLTEDLQIMSALDPRDQKDWIKERVQ 5 ( 1317) CYDNFYTLYENLKSGKITFAEVDAIFKDFVDKYDELKNDLKFMCTMNPQDQKGWISERVG // 0 ( 1207) QIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFT----------------DNF 1 ( 1342) QIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFT----------------DNF 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1323) QIKEYHHLHQAVDSAKVILEVKENLGLTGDFSVLHTLLSFT----------------D-L 5 ( 1377) QIKEYHTLHQAVSSAKVILQVRRALGVTGDFSVLNPLLNFTCHGSPGQYKLNFMFQADSF // 0 ( 1251) DDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFV 1 ( 1386) DDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFV 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1366) DKICHEKLNRINQHIIHAKKLLQDVSETRCQCLKELSQRKEFIGWVREALRGITELKVFV 5 ( 1437) EDFGNEKLDQISPQFIKAKQLLQDISEPRQRCLEELARQTELVAWLHKALEDINELKVFV // 0 ( 1311) DLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYL 1 ( 1446) DLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYL 2 ( -) ............................................................ 3 ( -) ............................................................ 4 ( 1426) DLASISAGENDIDVDRVACFHDAVQGYAPLLYELDTSAGFDEFVQHLKELWKALDNDHNL 5 ( 1497) DLASISAGENDIDVDRVACFHDAVQGYASLLYKMDERTNFSDFMNHLQELWRALDNDQHL // 0 ( 1371) PRKLVSLILSLMQILLNRALLSNVRAVTVEMVAHLCGRFVHSRFQ 1 ( 1506) PRKLVSLILSLMQILLNRALLSNVRAVTVEMVAHLCGRFVHSRFQ 2 ( -) ............................................. 3 ( -) ............................................. 4 ( 1486) PTKL......................................... 5 ( 1557) PDKL......................................... //