hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-15364448/chunk_1/iprscan-20080501-15364448.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0037 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00211.10.ls Adenylate and Guanylate cyclase catalyt 566.7 2.1e-167 2 PF00211.10.fs Adenylate and Guanylate cyclase catalyt 563.1 2.6e-166 2 PF06327.4.ls Domain of Unknown Function (DUF1053) 214.5 2.2e-61 1 PF06327.4.fs Domain of Unknown Function (DUF1053) 212.6 8.3e-61 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00211.10.ls 1/2 278 462 .. 1 223 [] 253.8 3.2e-73 PF00211.10.fs 1/2 278 462 .. 1 223 [] 252.0 1.1e-72 PF06327.4.fs 1/1 476 601 .. 1 127 [] 212.6 8.3e-61 PF06327.4.ls 1/1 476 601 .. 1 127 [] 214.5 2.2e-61 PF00211.10.fs 2/2 878 1077 .. 1 223 [] 311.1 1.9e-90 PF00211.10.ls 2/2 878 1077 .. 1 223 [] 312.9 5.3e-91 Alignments of top-scoring domains: PF00211.10.ls: domain 1 of 2, from 278 to 462: score 253.8, E = 3.2e-73 *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD +y +r++nV+il aDIvGFT+l+s +s p e+v +LN+l+++FD KIAA0037 278 LYVKRHQNVSILYADIVGFTQLASDCS----PKELVVVLNELFGKFD 320 eLldehkfgvyKvKTIGDaYMvasGlppaadqtkLakklqldsaaHaakl ++ ++ + ++K++GD+Y+++sGlp+ + Ha+ + KIAA0037 321 QIAKAN--ECMRIKILGDCYYCVSGLPVS-------------LPTHARNC 355 admALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviGlt ++m+Ldm +ai++v++ +++ + +++R+GiH+G V++GviG KIAA0037 356 VKMGLDMCQAIKQVREATGV--D-------INMRVGIHSGNVLCGVIG-- 394 akrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfefef +++++Ydvw+++V lA+RmE+ Gvpg ++h++e+t + L + +++e++ KIAA0037 395 LRKWQYDVWSHDVSLANRMEAAGVPG--RVHITEATLKHLDKAYEVEDG- 441 aleprgeveVkGkgkpGeietYfLkg<-* ++ ++ + k+ + i tY+++ KIAA0037 442 ---HGQQRDPYLKEMN--IRTYLVID 462 PF00211.10.fs: domain 1 of 2, from 278 to 462: score 252.0, E = 1.1e-72 *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD +y +r++nV+il aDIvGFT+l+s +s p e+v +LN+l+++FD KIAA0037 278 LYVKRHQNVSILYADIVGFTQLASDCS----PKELVVVLNELFGKFD 320 eLldehkfgvyKvKTIGDaYMvasGlppaadqtkLakklqldsaaHaakl ++ ++ + ++K++GD+Y+++sGlp+ + Ha+ + KIAA0037 321 QIAKAN--ECMRIKILGDCYYCVSGLPVS-------------LPTHARNC 355 admALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGpVvaGviGlt ++m+Ldm +ai++v++ +++ + +++R+GiH+G V++GviG KIAA0037 356 VKMGLDMCQAIKQVREATGV--D-------INMRVGIHSGNVLCGVIG-- 394 akrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLkeeesfefef +++++Ydvw+++V lA+RmE+ Gvpg ++h++e+t + L + +++e++ KIAA0037 395 LRKWQYDVWSHDVSLANRMEAAGVPG--RVHITEATLKHLDKAYEVEDG- 441 aleprgeveVkGkgkpGeietYfLkg<-* ++ ++ + k+ + i tY+++ KIAA0037 442 ---HGQQRDPYLKEMN--IRTYLVID 462 PF06327.4.fs: domain 1 of 1, from 476 to 601: score 212.6, E = 8.3e-61 *->kglkaelesltdrrsnsmtrylesWgPerPFaNLnsresglkaatsi +++k++ ++l++r+s++mtrylesWg++rPFa+Ln+res+++++t++ KIAA0037 476 PRPKGD-AALKMRASVRMTRYLESWGAARPFAHLNHRESVSSGETHV 521 giddkpkhrvsaqvrtnpelhskKgrdEldEiDefieqaIdirSndklCw +++++pk+++++++rt+++++s+Kgr+E+d++D+++++aI+++S++++C+ KIAA0037 522 PNGRRPKSVPQRHRRTPDRSMSPKGRSEDDSYDDEMLSAIEGLSSTRPCC 571 kRrEhlnpftLtFkdkslEkKYsqlrdprF<-* ++++++++f+++F +k++E++Y+++++pr+ KIAA0037 572 SKSDDFYTFGSIFLEKGFEREYRLAPIPRA 601 PF06327.4.ls: domain 1 of 1, from 476 to 601: score 214.5, E = 2.2e-61 *->kglkaelesltdrrsnsmtrylesWgPerPFaNLnsresglkaatsi +++k++ ++l++r+s++mtrylesWg++rPFa+Ln+res+++++t++ KIAA0037 476 PRPKGD-AALKMRASVRMTRYLESWGAARPFAHLNHRESVSSGETHV 521 giddkpkhrvsaqvrtnpelhskKgrdEldEiDefieqaIdirSndklCw +++++pk+++++++rt+++++s+Kgr+E+d++D+++++aI+++S++++C+ KIAA0037 522 PNGRRPKSVPQRHRRTPDRSMSPKGRSEDDSYDDEMLSAIEGLSSTRPCC 571 kRrEhlnpftLtFkdkslEkKYsqlrdprF<-* ++++++++f+++F +k++E++Y+++++pr+ KIAA0037 572 SKSDDFYTFGSIFLEKGFEREYRLAPIPRA 601 PF00211.10.fs: domain 2 of 2, from 878 to 1077: score 311.1, E = 1.9e-90 *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD y+q+yd+V+++Fa++++F ++++++vN++++e++rlLN+++++FD KIAA0037 878 WYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFD 924 eLldehkf.gvyKvKTIGDaYMvasGlppaadqt........kLakklql eLl ++kf+gv+K+KTIG++YM+a+Gl++a ++++++ ++ KIAA0037 925 ELLLKPKFsGVEKIKTIGSTYMAAAGLSVA---SghenqeleR------- 964 dsaaHaakladmALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGp + aH+ +++++ +++ ++ +n +++n +r+R+Gi++Gp KIAA0037 965 -QHAHIGVMVEFSIALMSKLDGINRHSFN--S-------FRLRVGINHGP 1004 VvaGviGltakrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLk V+aGviG a++p+Yd+wG+TVN+ASRmEStG+ g kI+v+eet ++L+ KIAA0037 1005 VIAGVIG--ARKPQYDIWGNTVNVASRMESTGELG--KIQVTEETCTILQ 1050 eeesfefefaleprgeveVkGkgkpGeietYfLkg<-* +++ +++e+ rg ++VkGkg+ + tYf+ KIAA0037 1051 GLG-YSCEC----RGLINVKGKGE---LRTYFVCT 1077 PF00211.10.ls: domain 2 of 2, from 878 to 1077: score 312.9, E = 5.3e-91 *->vyaqrydnVtilFaDIvGFTalssrhsvNngpeevvrlLNdlytrFD y+q+yd+V+++Fa++++F ++++++vN++++e++rlLN+++++FD KIAA0037 878 WYHQSYDCVCVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFD 924 eLldehkf.gvyKvKTIGDaYMvasGlppaadqt........kLakklql eLl ++kf+gv+K+KTIG++YM+a+Gl++a ++++++ ++ KIAA0037 925 ELLLKPKFsGVEKIKTIGSTYMAAAGLSVA---SghenqeleR------- 964 dsaaHaakladmALdmveaiqevnvehanrepPtvLyrGlrvRiGiHtGp + aH+ +++++ +++ ++ +n +++n +r+R+Gi++Gp KIAA0037 965 -QHAHIGVMVEFSIALMSKLDGINRHSFN--S-------FRLRVGINHGP 1004 VvaGviGltakrprYdvwGdTVNlASRmEStGvpgsekIhvseetyrlLk V+aGviG a++p+Yd+wG+TVN+ASRmEStG+ g kI+v+eet ++L+ KIAA0037 1005 VIAGVIG--ARKPQYDIWGNTVNVASRMESTGELG--KIQVTEETCTILQ 1050 eeesfefefaleprgeveVkGkgkpGeietYfLkg<-* +++ +++e+ rg ++VkGkg+ + tYf+ KIAA0037 1051 GLG-YSCEC----RGLINVKGKGE---LRTYFVCT 1077 //