HUGE

Gene/Protein Characteristic Table for KIAA0102

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00409
Accession No. :	D14658
Description :	Signal peptidase complex subunit 2.
HUGO Gene Name :	signal peptidase complex subunit 2 homolog (S. cerevisiae) (SPCS2)
Clone Name :	ha00791 [Vector Info]
Flexi ORF Clone :	pF1KSDA0102
Source :	Myeloblast cell line (KG-1)

Features of the cloned DNA sequence	Description

Length: 1370 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 691 bp

Genome contig ID gi51511727f_74237981
PolyA signal sequence
(AATAAA,-21)
+----*----+----*----+----*----+----
CTAAAATTTTTTTCAATAAAAGGAAGGAAGATGTG
Flanking genome sequence
(128448 - 128497)
----+----*----+----*----+----*----+----*----+----*
AAAAAAATGGAGTCATAGTTTTGATGGAGAGAACAGAGAAACAAGTGTTA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 11 f 74337981 74366427 5 100.0 Perfect prediction

ContigView(URL based/DAS) 1 r 28294148 28295518 1 99.0 Perfect prediction

Features of the protein sequence	Description

Length: 225 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
Q15005	7.7e-90	100.0	Signal peptidas...	Homo sapiens
BAG56680	1.4e-89	99.6	unnamed protein...	Homo sapiens
AAH64957	1.6e-89	99.6	SPCS2 protein [...	Homo sapiens
XP_001174940	1.9e-89	99.6	hypothetical pr...	Pan troglodytes
EAX07712	1.8e-88	99.1	hCG18930 [Homo ...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR009582 42 223 PF06703 Microsomal signal peptidase 25 kDa subunit

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR009582	42	223	PF06703	Microsomal signal peptidase 25 kDa subunit

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 82 GRLTICTISCFFAIVALIWDYMH 104 PRIMARY 23

2 112 VLALCVISYFVMMGILTIYTSY 133 SECONDARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	82	GRLTICTISCFFAIVALIWDYMH	104	PRIMARY	23
2	112	VLALCVISYFVMMGILTIYTSY	133	SECONDARY	22

Expression profile	Description

: Northern blot Description

Northern blot	Description

RH mapping information	Description

Chromosome No.

: 11

Experimental conditions

Panel name	: Genebridge 4
Primer_f	: AGTGGGAGAACAAAGCAGCAG
Primer_r	: TTTTTATCTCCCCCACCCCCC
PCR product length	: 223 bp
PCR conditions	: 95 °C15 sec70 °C60 sec32 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	691 bp
Genome contig ID	gi51511727f_74237981
PolyA signal sequence (AATAAA,-21)	+--------+--------+----*----+---- CTAAAATTTTTTTCAATAAAAGGAAGGAAGATGTG
Flanking genome sequence (128448 - 128497)	----+--------+--------+--------+--------+----* AAAAAAATGGAGTCATAGTTTTGATGGAGAGAACAGAGAAACAAGTGTTA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	11	f	74337981	74366427	5	100.0	Perfect prediction
ContigView(URL based/DAS)	1	r	28294148	28295518	1	99.0	Perfect prediction

Gene/Protein Characteristic Table for KIAA0102

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information