hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/smart.HMMs.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-22205650/chunk_1/iprscan-20080501-22205650.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0279 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- SM00112 841.2 2.1e-248 9 SM00282 211.0 1.1e-58 2 SM00181 169.5 3.3e-46 6 SM00179 116.7 2.7e-30 5 SM00303 103.1 3.2e-26 1 SM00008 88.2 9.6e-22 1 SM00180 54.6 1.2e-11 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- SM00112 1/9 134 218 .. 1 121 [] 102.8 4e-26 SM00112 2/9 242 328 .. 1 121 [] 112.1 6.1e-29 SM00112 3/9 352 434 .. 1 121 [] 105.7 5.4e-27 SM00112 4/9 458 539 .. 1 121 [] 116.2 3.6e-30 SM00112 5/9 563 641 .. 1 121 [] 75.4 7.1e-18 SM00112 6/9 665 744 .. 1 121 [] 114.2 1.5e-29 SM00112 7/9 768 850 .. 1 121 [] 111.3 1.1e-28 SM00112 8/9 874 952 .. 1 121 [] 95.6 6e-24 SM00112 9/9 980 1056 .. 1 121 [] 7.9 0.4 SM00181 1/6 1162 1217 .. 1 32 [] 27.1 0.0024 SM00179 1/5 1219 1255 .. 1 34 [] 43.4 3e-08 SM00181 2/6 1222 1255 .. 1 32 [] 32.3 6.5e-05 SM00181 3/6 1262 1297 .. 1 32 [] 22.3 0.069 SM00179 2/5 1263 1297 .. 1 34 [] 21.1 0.0041 SM00282 1/2 1318 1485 .. 1 137 [] 115.1 7.6e-30 SM00179 3/5 1505 1541 .. 1 34 [] 28.3 0.00052 SM00181 4/6 1508 1541 .. 1 32 [] 30.9 0.00018 SM00282 2/2 1567 1701 .. 1 137 [] 95.9 4.8e-24 SM00179 4/5 1726 1760 .. 1 34 [] 17.7 0.011 SM00181 5/6 1727 1760 .. 1 32 [] 28.1 0.0012 SM00181 6/6 1762 1798 .. 1 32 [] 28.8 0.00074 SM00179 5/5 1764 1798 .. 1 34 [] 6.2 0.28 SM00180 1/1 1855 1900 .. 1 42 [] 54.6 1.2e-11 SM00008 1/1 1903 1965 .. 1 89 [] 88.2 9.6e-22 SM00303 1/1 2246 2299 .. 1 51 [] 103.1 3.2e-26 Alignments of top-scoring domains: SM00112: domain 1 of 9, from 134 to 218: score 102.8, E = 4e-26 *->vsAtDaDsgsngeNgkpgdaevvtYsils........lFsIdpetGt ++A+D+D+g e g+ ++Y++ +++++++Fs+dp tG KIAA0279 134 LRAIDPDEG---EAGR------LEYTMDAlfdsrsnqFFSLDPVTG- 170 ngpsLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppg +tt+++LDRE++ s++ ++v+A+D+G+p+ KIAA0279 171 ----------AVTTAEELDRETK---------STHVFRVTAQDHGMPR-- 199 dssptrksqqtpplsstatvtvtVlDvNDNaP<-* +s+ at+t+ V+D ND+ P KIAA0279 200 -------------RSALATLTILVTDTNDHDP 218 SM00112: domain 2 of 9, from 242 to 328: score 112.1, E = 6.1e-29 *->vsAtDaDsgsngeNgkpgdaevvtYsils........lFsIdpetGt v+AtD D++ +N++ + Y++l+++++++++ F+Idp++G KIAA0279 242 VRATDGDAP---PNAN------ILYRLLEgsggspseVFEIDPRSG- 278 ngpsLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppg +i+t++p DREe ++Y+LtveA+D+G p++ KIAA0279 279 ----------VIRTRGPVDREEV---------ESYQLTVEASDQGRDPGP 309 dssptrksqqtpplsstatvtvtVlDvNDNaP<-* +s+ta v V+D NDNaP KIAA0279 310 -------------RSTTAAVFLSVEDDNDNAP 328 SM00112: domain 3 of 9, from 352 to 434: score 105.7, E = 5.4e-27 *->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp v+A+D+D g +N+ v+Ysi s++ +++F +d++tG KIAA0279 352 VTASDRDKG---SNAV------VHYSIMSgnargQFYLDAQTG---- 385 sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss + ++ pLD+E++ +eYtL+v+A+DgG pp KIAA0279 386 -------ALDVVSPLDYETT---------KEYTLRVRAQDGGRPPL---- 415 ptrksqqtpplsstatvtvtVlDvNDNaP<-* + vtv+VlD+NDNaP KIAA0279 416 ----------SNVSGLVTVQVLDINDNAP 434 SM00112: domain 4 of 9, from 458 to 539: score 116.2, E = 3.6e-30 *->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp v+A+DaD+g +N++ ++Y++ + +++ +F+I+ tG KIAA0279 458 VQAIDADAG---DNAR------LEYRLAGvghdfPFTINNGTG---- 491 sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss +i+++++LDREe + Y++ veA+D+G+p KIAA0279 492 -------WISVAAELDREEV---------DFYSFGVEARDHGTPA----- 520 ptrksqqtpplsstatvtvtVlDvNDNaP<-* l+++a+v vtVlDvNDN P KIAA0279 521 ----------LTASASVSVTVLDVNDNNP 539 SM00112: domain 5 of 9, from 563 to 641: score 75.4, E = 7.1e-18 *->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp vsA+D+D+ + +tY+i+s+++++ FsI +++G KIAA0279 563 VSAVDRDA-----HSV------ITYQITSgntrnRFSITSQSG---- 594 sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss + ++++ pLD+ +Y L v+A+Dg KIAA0279 595 -----GGLVSLALPLDYKLE---------RQYVLAVTASDGT-------- 622 ptrksqqtpplsstatvtvtVlDvNDNaP<-* +++ta+++v+V+D N ++P KIAA0279 623 ----------RQDTAQIVVNVTDANTHRP 641 SM00112: domain 6 of 9, from 665 to 744: score 114.2, E = 1.5e-29 *->vsAtDaDsgsngeNgkpgdaevvtYsils...lFsIdpetGtngpsL +sAtD+D+g eN++ +tY ++++ ++F+Id++tG KIAA0279 665 ISATDEDTG---ENAR------ITYFMEDsipQFRIDADTG------ 696 vkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdsspt +tt+++LD+E+q +YtL ++A+D+G p+ KIAA0279 697 -----AVTTQAELDYEDQ---------VSYTLAITARDNGIPQ------- 725 rksqqtpplsstatvtvtVlDvNDNaP<-* +s+t+ + + V DvNDNaP KIAA0279 726 --------KSDTTYLEILVNDVNDNAP 744 SM00112: domain 7 of 9, from 768 to 850: score 111.3, E = 1.1e-28 *->vsAtDaDsgsngeNgkpgdaevvtYsils......lFsIdpetGtng +sAtD+Dsg Ng+ v Y++ +++++++ F +++++G KIAA0279 768 ISATDRDSG---LNGR------VFYTFQGgddgdgDFIVESTSG--- 802 psLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgds i++t+++LDRE+ ++Y L+ A+D+G+pp KIAA0279 803 --------IVRTLRRLDRENV---------AQYVLRAYAVDKGMPP---- 831 sptrksqqtpplsstatvtvtVlDvNDNaP<-* ++ +vtvtVlDvNDN+P KIAA0279 832 -----------ARTPMEVTVTVLDVNDNPP 850 SM00112: domain 8 of 9, from 874 to 952: score 95.6, E = 6e-24 *->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp v+AtD+D+g +N++ + Y+i++++ ++ F++d +G KIAA0279 874 VTATDPDEG---TNAQ------IMYQIVEgnipeVFQLDIFSG---- 907 sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss ++t++ LD+E++ +eY L+++At + KIAA0279 908 -------ELTALVDLDYEDR---------PEYVLVIQATSAP-------- 933 ptrksqqtpplsstatvtvtVlDvNDNaP<-* l s atv+v++lD NDN+P KIAA0279 934 ----------LVSRATVHVRLLDRNDNPP 952 SM00112: domain 9 of 9, from 980 to 1056: score 7.9, E = 0.4 *->vsAtDaDsgsngeNgkpgdaevvtYsils.....lFsIdpetGtngp v A+D+D + +tYs++++++ +l ++++tG KIAA0279 980 VPAHDPDI-----SDS------LTYSFERgnelsLVLLNASTG---- 1011 sLvkleiiitttkpLDREeqflkreqtdeseYtLtveAtDgGgpppgdss +++++++LD e + v ++Dg KIAA0279 1012 -------ELKLSRALDNNRP---------LEAIMSVLVSDGV-------- 1037 ptrksqqtpplsstatvtvtVlDvNDNaP<-* +s ta+ +V+ + D KIAA0279 1038 ----------HSVTAQCALRVTIITDEML 1056 SM00181: domain 1 of 6, from 1162 to 1217: score 27.1, E = 0.0024 *->eCa..pCsnGgtEqnGtCi..........................sy C+++pC+n +C++ + +++ + +++ ++ ++ ++ KIAA0279 1162 ICLrePCENY-----MRCVsvlrfdssapfiasssvlfrpihpvgGL 1203 tC.CpgpGytg.rCe<-* +C+Cp pG+tg++Ce KIAA0279 1204 RCrCP-PGFTGdYCE 1217 SM00179: domain 1 of 5, from 1219 to 1255: score 43.4, E = 3e-08 *->DiDEC...pCqnGGptgtCiN.vGSYrC.CppGyt.rnCe<-* +D C ++pC+++G +C+ ++G+Y+C C++Gyt+ +Ce KIAA0279 1219 EVDLCysrPCGPHG---RCRSrEGGYTClCRDGYTgEHCE 1255 SM00181: domain 2 of 6, from 1222 to 1255: score 32.3, E = 6.5e-05 *->eCa..pCsnGgtEqnGtCi....sytC.CpgpGytg.rCe<-* C ++pC+++ G+C++++++ytC C+ +Gytg++Ce KIAA0279 1222 LCYsrPCGPH-----GRCRsregGYTClCR-DGYTGeHCE 1255 SM00181: domain 3 of 6, from 1262 to 1297: score 22.3, E = 0.069 *->eCa..pCsnGgtEqnGtCi.....sytC.CpgpGytg.rCe<-* C ++ C nG GtC++ ++++C+Cp+ ++ ++C+ KIAA0279 1262 RCTpgVCKNG-----GTCVnllvgGFKCdCPSGDFEKpYCQ 1297 SM00179: domain 2 of 5, from 1263 to 1297: score 21.1, E = 0.0041 *->DiDEC...pCqnGGptgtCiN..vGSYrC.Cpp.Gyt.rnCe<-* C++++C nGG tC+N vG+++C+Cp + ++++ C+ KIAA0279 1263 ----CtpgVCKNGG---TCVNllVGGFKCdCPSgDFEkPYCQ 1297 SM00282: domain 1 of 2, from 1318 to 1485: score 115.1, E = 7.6e-30 *->t.lsisfsFrTtspnGlLlyag....ggdflaleLvlEDsdgdGrlv ++++ +sF T + +GlLly+g+ ++++df+ale++ + +++ KIAA0279 1318 FhFTLALSFATKERDGLLLYNGrfneKHDFVALEVI------QEQVQ 1358 lrydlGssttggparltsdsdrptplnDGqWHrVsvern........... l+++ G+ +++++++ p ++DGqWH+V++ +++++ ++++ + KIAA0279 1359 LTFSAGE----STTTVSPFV--PGGVSDGQWHTVQLKYYnkpllgqtglp 1402 .....grsvtLsVDg....gnpvsges................t.Ldldk +++++++ ++++VDg +++ + g+ ++ + ++++++++++Ldl+ KIAA0279 1403 qgpseQKVAVVTVDGcdtgVALRFGSVlgnyscaaqgtqggskKsLDLT- 1451 eesgplylGGlPe.....lpvspgFrGCirnlrvngk<-* gpl lGG+P+ +++ + F+GC+rnl+v+++ KIAA0279 1452 ---GPLLLGGVPDlpesfPVRMRQFVGCMRNLQVDSR 1485 SM00179: domain 3 of 5, from 1505 to 1541: score 28.3, E = 0.00052 *->DiDEC...pCqnGGptgtCiN.vGSYrC.CppGyt.rnCe<-* + C+++ C+nGG tC+N+ ++C+Cp G+ +++C KIAA0279 1505 KKNVCdsnTCHNGG---TCVNqWDAFSCeCPLGFGgKSCA 1541 SM00181: domain 4 of 6, from 1508 to 1541: score 30.9, E = 0.00018 *->eCa..pCsnGgtEqnGtCi....sytC.CpgpGytg.rCe<-* C+++ C+nG GtC++ + ++C+Cp G+ g++C KIAA0279 1508 VCDsnTCHNG-----GTCVnqwdAFSCeCP-LGFGGkSCA 1541 SM00282: domain 2 of 2, from 1567 to 1701: score 95.9, E = 4.8e-24 *->t.lsisfsFrTtspnGlLlyag..ggdflaleLvlEDsdgdGrlvlr +++++s++FrT++++G+Ll+a ++g + ++l+L+ +G+++l+ KIAA0279 1567 QpWHLSLMFRTRQADGVLLQAItrGRSTITLQLR------EGHVMLS 1607 ydlGssttggparltsdsdrptplnDGqWHrVsvern....grsvtLsVD ++ + +++l+ ++ + nDG WH+ ++ +++ +++ Ls D KIAA0279 1608 VEGTG---LQASSLRLEP---GRANDGDWHHAQLALGasggPGHAILSFD 1651 ggnpvsges....t.LdldkeesgplylGGlPe..lpvspgFrGCirnlr + ++++e + +++ l+ +++ +GG+P + + v gFrGC++++r KIAA0279 1652 -YGQQRAEGnlgpRlHGLH---LSNITVGGIPGpaGGVARGFRGCLQGVR 1697 vngk<-* v KIAA0279 1698 VSDT 1701 SM00179: domain 4 of 5, from 1726 to 1760: score 17.7, E = 0.011 *->DiDEC...pCqnGGptgtCiN.vGSYrC.CppGyt.rnCe<-* D C+++pC+ ++ C N+ SY+C+C+pGy++ nC+ KIAA0279 1726 --DPCdsnPCPANS---YCSNdWDSYSCsCDPGYYgDNCT 1760 SM00181: domain 5 of 6, from 1727 to 1760: score 28.1, E = 0.0012 *->eCa..pCsnGgtEqnGtCi....sytC.CpgpGytg.rCe<-* +C+++pC + C ++ +sy+C+C pGy+g++C KIAA0279 1727 PCDsnPCPANS-----YCSndwdSYSCsCD-PGYYGdNCT 1760 SM00181: domain 6 of 6, from 1762 to 1798: score 28.8, E = 0.00074 *->eCa..pCsnGgtEqnGtCi.......sytC.CpgpGytg.rCe<-* C+ +pC++ +C+++++ +++ytC+Cp p y g++Ce KIAA0279 1762 VCDlnPCEHQS-----VCTrkpsaphGYTCeCP-PNYLGpYCE 1798 SM00179: domain 5 of 5, from 1764 to 1798: score 6.2, E = 0.28 *->DiDECpCqnGGptgtCiN.vG...SYrC.CppGyt.rnCe<-* D + pC + + +C+ ++ +++Y+C+Cpp y ++ Ce KIAA0279 1764 DLN--PCEHQS---VCTRkPSaphGYTCeCPPNYLgPYCE 1798 SM00180: domain 1 of 1, from 1855 to 1900: score 54.6, E = 1.2e-11 *->CdCnlpppvG.....Cdp.tGqClnCkpnttGGrrCdderCapGyy. CdC+ p+G+ ++ Cdp++GqC+ Ckp+++G r+Cd rC + + + KIAA0279 1855 CDCY---PTGslsrvCDPeDGQCP-CKPGVIG-RQCD--RCDNPFAe 1894 ....gC<-* +++gC KIAA0279 1895 vttnGC 1900 SM00008: domain 1 of 1, from 1903 to 1965: score 88.2, E = 9.6e-22 *->tdlgCpatwDgiiCWpsTpaGqlvavpCPeyfsgfsnktggNrtqGn ++ Cp++++ +i+Wp+T++G +a+pCP+++ g+ KIAA0279 1903 NYDSCPRAIEAGIWWPRTRFGLPAAAPCPKGSFGT------------ 1937 asRnCtedtGvGgWsepfpgaeSnrtWpnysnCtsndyeelk<-* a+R+C+e++ gW++ pn++nCts++++elk KIAA0279 1938 AVRHCDEHR---GWLP-----------PNLFNCTSITFSELK 1965 SM00303: domain 1 of 1, from 2246 to 2299: score 103.1, E = 3.2e-26 *->snpiCvfWdese....tgeWstrGCelvetnkpthttCsCnHLTsFA ++piCvfW++s ++tg+Ws+rGCe+v +n+ +h++C+CnH+TsFA KIAA0279 2246 TKPICVFWNHSIlvsgTGGWSARGCEVVFRNE-SHVSCQCNHMTSFA 2291 vLmdvspn<-* vLmdvs++ KIAA0279 2292 VLMDVSRR 2299 //