HUGE

Gene/Protein Characteristic Table for KIAA0319

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00504
Accession No. :	AB002317
Description :
HUGO Gene Name :
Clone Name :	hg00378 [Vector Info]
Flexi ORF Clone :	pF1KSDA0319
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 6791 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 3061 bp

Genome contig ID gi89161210r_24552469
PolyA signal sequence
(AATAAA,-25)
+----*----+----*----+----*----+----
TGTGTTCATAAATAAAGTTTTATTGGAACATATCC
Flanking genome sequence
(99842 - 99793)
----+----*----+----*----+----*----+----*----+----*
ACATTCACTGATTTATGTATTATCTATGGCTGTTCTTATGTTACAACAAA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 6 r 24652311 24754362 21 99.1 Perfect prediction

Features of the protein sequence	Description

Length: 1109 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
BAG59087	0	99.7	unnamed protein...	Homo sapiens
BAG58068	0	99.8	unnamed protein...	Homo sapiens
AAI44629	0	94.0	Unknown (protei...	Homo sapiens
BAE28638	0	75.3	unnamed protein...	Mus musculus
EDL30274	3.5e-162	48.1	expressed seque...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB058740	1.1e-82	62.0	KIAA1837

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMSmart IPR011106 57 139 SM00765 Seven cysteines

IPR003961 342 455 SM00060 Fibronectin

IPR000601 378 464 SM00089 PKD

IPR003961 471 549 SM00060 Fibronectin

IPR000601 472 561 SM00089 PKD

IPR000601 567 657 SM00089 PKD

IPR003961 630 739 SM00060 Fibronectin

IPR000601 658 751 SM00089 PKD

IPR003961 756 836 SM00060 Fibronectin

IPR000601 757 848 SM00089 PKD

ProfileScan IPR013980 50 136 PS50986 Seven cysteines

IPR000601 582 655 PS50093 PKD

Search method	interpro_ID	From	To	Entry	Definition
HMMSmart	IPR011106	57	139	SM00765	Seven cysteines
IPR003961	342	455	SM00060	Fibronectin
IPR000601	378	464	SM00089	PKD
IPR003961	471	549	SM00060	Fibronectin
IPR000601	472	561	SM00089	PKD
IPR000601	567	657	SM00089	PKD
IPR003961	630	739	SM00060	Fibronectin
IPR000601	658	751	SM00089	PKD
IPR003961	756	836	SM00060	Fibronectin
IPR000601	757	848	SM00089	PKD
ProfileScan	IPR013980	50	136	PS50986	Seven cysteines
IPR000601	582	655	PS50093	PKD

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 37 TMAPPTGVLSSLLLLVTIAGCA 58 PRIMARY 22

2 994 FYVTVLAFTLIVLTGGFTWLCIC 1016 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	37	TMAPPTGVLSSLLLLVTIAGCA	58	PRIMARY	22
2	994	FYVTVLAFTLIVLTGGFTWLCIC	1016	PRIMARY	23

Expression profile	Description

: RT-PCR Description

Experimental conditions

Primer_f
: AGACCCACTTTTCGGCTCATG

Primer_r
: TTTATGCTTCAGGGTAGAGGG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR	Description

RH mapping information	Description

Chromosome No.

: 6

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: AGACCCACTTTTCGGCTCATG
Primer_r	: TTTATGCTTCAGGGTAGAGGG
PCR product length	: 97 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	3061 bp
Genome contig ID	gi89161210r_24552469
PolyA signal sequence (AATAAA,-25)	+--------+--------+----*----+---- TGTGTTCATAAATAAAGTTTTATTGGAACATATCC
Flanking genome sequence (99842 - 99793)	----+--------+--------+--------+--------+----* ACATTCACTGATTTATGTATTATCTATGGCTGTTCTTATGTTACAACAAA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	6	r	24652311	24754362	21	99.1	Perfect prediction

Gene/Protein Characteristic Table for KIAA0319

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information