hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-00513704/chunk_1/iprscan-20080502-00513704.nocrc
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Query sequence: KIAA0362
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00621.11.fs RhoGEF domain                                  163.9    2.8e-48   1
PF00621.11.ls RhoGEF domain                                  165.7    1.1e-46   1
PF00169.19.fs PH domain                                       52.7    1.4e-15   1
PF00169.19.ls PH domain                                       54.7    2.8e-13   1
PF00435.11.fs Spectrin repeat                                 31.4    8.1e-09   1
PF00435.11.ls Spectrin repeat                                 33.3    7.8e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00435.11.fs   1/1     366   471 ..     1   111 []    31.4  8.1e-09
PF00435.11.ls   1/1     366   471 ..     1   111 []    33.3  7.8e-07
PF00621.11.ls   1/1     650   825 ..     1   207 []   165.7  1.1e-46
PF00621.11.fs   1/1     650   825 ..     1   207 []   163.9  2.8e-48
PF00169.19.fs   1/1     845   960 ..     1    92 []    52.7  1.4e-15
PF00169.19.ls   1/1     845   960 ..     1    92 []    54.7  2.8e-13

Alignments of top-scoring domains:
PF00435.11.fs: domain 1 of 1, from 366 to 471: score 31.4, E = 8.1e-09
                   *->lllqqFqrdaddlesWieek.ealLssedyegkdleevqaLlkqlkH
                      l+l+ F +  +++++ ++ ++ ++++ +d+ g++l++v+ Ll+   +
    KIAA0362   366    LQLRHFEQGFREVKAILDAAsQKIATFTDI-GNSLAHVEHLLR--DL 409  

                   kaleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWe
                     +e+   +  +r +al     +e+L i ++hya + i+ +++eL+++ +
    KIAA0362   410 ASFEEKSGVAVERARALS--LDGEQL-IGNKHYAVDSIRPKCQELRHLCD 456  

                   qLlelaaeRkqkLee<-*
                   q  + +a+R+  L     
    KIAA0362   457 QFSAEIARRRGLLSK    471  

PF00435.11.ls: domain 1 of 1, from 366 to 471: score 33.3, E = 7.8e-07
                   *->lllqqFqrdaddlesWieek.ealLssedyegkdleevqaLlkqlkH
                      l+l+ F +  +++++ ++ ++ ++++ +d+ g++l++v+ Ll+   +
    KIAA0362   366    LQLRHFEQGFREVKAILDAAsQKIATFTDI-GNSLAHVEHLLR--DL 409  

                   kaleaelaahqdrvealninelaekLiideghyaseeiqerleeLnerWe
                     +e+   +  +r +al     +e+L i ++hya + i+ +++eL+++ +
    KIAA0362   410 ASFEEKSGVAVERARALS--LDGEQL-IGNKHYAVDSIRPKCQELRHLCD 456  

                   qLlelaaeRkqkLee<-*
                   q  + +a+R+  L     
    KIAA0362   457 QFSAEIARRRGLLSK    471  

PF00621.11.ls: domain 1 of 1, from 650 to 825: score 165.7, E = 1.1e-46
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLt...pddie
                      v +Ell TE++Yv++L  ++ +y+++++++ +    lL+++ +++++
    KIAA0362   650    VMSELLDTERAYVEELLCVLEGYAAEMDNPLMAH--LLStglHNKKD 694  

                   tiFsNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFl
                    +F+N+e+iy fh+++++ +Le+                  ++ +G +Fl
    KIAA0362   695 VLFGNMEEIYHFHNRIFLRELENYTDC--------------PELVGRCFL 730  

                   elkaeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntg
                   e+ ++f q+Y++Yc+nkp+++ l+++     s + F+++++++  +    
    KIAA0362   731 ERMEDF-QIYEKYCQNKPRSESLWRQ----CSDCPFFQECQRKLDH---- 771  

                   AkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkka
                         kl+L+s+LlkPvqRi++Y+LLLke Lk++     +++ edL++a
    KIAA0362   772 ------KLSLDSYLLKPVQRITKYQLLLKEMLKYSR---NCEGAEDLQEA 812  

                   ldalqdlaksiNe<-*
                   l+ + +++k +N+   
    KIAA0362   813 LSSILGILKAVND    825  

PF00621.11.fs: domain 1 of 1, from 650 to 825: score 163.9, E = 2.8e-48
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLt...pddie
                      v +Ell TE++Yv++L  ++ +y+++++++ +    lL+++ +++++
    KIAA0362   650    VMSELLDTERAYVEELLCVLEGYAAEMDNPLMAH--LLStglHNKKD 694  

                   tiFsNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFl
                    +F+N+e+iy fh+++++ +Le+                  ++ +G +Fl
    KIAA0362   695 VLFGNMEEIYHFHNRIFLRELENYTDC--------------PELVGRCFL 730  

                   elkaeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntg
                   e+ ++f q+Y++Yc+nkp+++ l+++     s + F+++++++  +    
    KIAA0362   731 ERMEDF-QIYEKYCQNKPRSESLWRQ----CSDCPFFQECQRKLDH---- 771  

                   AkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkka
                         kl+L+s+LlkPvqRi++Y+LLLke Lk++     +++ edL++a
    KIAA0362   772 ------KLSLDSYLLKPVQRITKYQLLLKEMLKYSR---NCEGAEDLQEA 812  

                   ldalqdlaksiNe<-*
                   l+ + +++k +N+   
    KIAA0362   813 LSSILGILKAVND    825  

PF00169.19.fs: domain 1 of 1, from 845 to 960: score 52.7, E = 1.4e-15
                   *->vikeGwLlkkg............gkkswkkRyfvLfddvLlyykdkk
                      + ++G +++++++++++++ ++ ++ ++ +R+++L+++  l++k++ 
    KIAA0362   845    LLMQGSFSVWTdhkrghtkvkelARFKPMQRHLFLHEKAVLFCKKRE 891  

                   ...........kkpkgsipLsgiqvtkvpdnkrkncFeirt.dr.etlll
                   +++++ ++ +++++k s+++  + +t+ +++ +   Fei+ + r+e++++
    KIAA0362   892 engegyekapsYSYKQSLNMAAVGITENVKG-DAKKFEIWYnAReEVYIV 940  

                   qaeseeerkeWvkaiqsair<-*
                   qa+++e +  Wv+ i++++    
    KIAA0362   941 QAPTPEIKAAWVNEIRKVLT    960  

PF00169.19.ls: domain 1 of 1, from 845 to 960: score 54.7, E = 2.8e-13
                   *->vikeGwLlkkg............gkkswkkRyfvLfddvLlyykdkk
                      + ++G +++++++++++++ ++ ++ ++ +R+++L+++  l++k++ 
    KIAA0362   845    LLMQGSFSVWTdhkrghtkvkelARFKPMQRHLFLHEKAVLFCKKRE 891  

                   ...........kkpkgsipLsgiqvtkvpdnkrkncFeirt.dr.etlll
                   +++++ ++ +++++k s+++  + +t+ +++ +   Fei+ + r+e++++
    KIAA0362   892 engegyekapsYSYKQSLNMAAVGITENVKG-DAKKFEIWYnAReEVYIV 940  

                   qaeseeerkeWvkaiqsair<-*
                   qa+++e +  Wv+ i++++    
    KIAA0362   941 QAPTPEIKAAWVNEIRKVLT    960  

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